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Entry: PS00498

General information about the entry

Entry name [info] TYROSINASE_2
Accession [info] PS00498
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED;
01-MAY-1991 DATA UPDATE;
22-APR-2020 INFO UPDATE.
PROSITE Doc. [info] PDOC00398

Name and characterization of the entry

Description [info] Tyrosinase and hemocyanins CuB-binding region signature.
Pattern [info]
D-P-x-F-[LIVMFYW]-x(2)-H-x(3)-D.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2020_02 which contains 562'253 sequence entries.


Total number of hits 110 in 103 different sequences
Number of true positive hits 105 in 98 different sequences
Number of 'unknown' hits 0
Number of false positive hits 5 in 5 different sequences
Number of false negative sequences 1
Number of 'partial' sequences 35
Precision (true positives / (true positives + false positives)) 95.45 %
Recall (true positives / (true positives + false negatives)) 99.06 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 6
Site [info] copper at position 7
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
98 sequences

AS1_ANTMA   (Q9FRX6    ), GRIF_STRGG  (B1VTI5    ), HC2C_MEGCR  (P81732    ), 
HCY2A_RAPVE (P80960    ), HCY2E_RAPVE (P83040    ), HCY2_CARAE  (P84293    ), 
HCY2_LIMPO  (P04253    ), HCY6_ANDAU  (P80476    ), HCYA_APHSP  (P14750    ), 
HCYA_ENTDO  (P12659    ), HCYA_PANIN  (P04254    ), HCYA_SCUCO  (Q95P08    ), 
HCYB_APHSP  (Q9NFH9    ), HCYB_ASTLP  (P83180    ), HCYB_HELPO  (P12031    ), 
HCYB_PANIN  (P10787    ), HCYB_SCUCO  (Q8IFJ8    ), HCYC_APHSP  (Q9NFL6    ), 
HCYC_PANIN  (P80096    ), HCYC_SCUCO  (Q8T115    ), HCYD_APHSP  (P02241    ), 
HCYD_SCUCO  (Q95P07    ), HCYE_APHSP  (P02242    ), HCYF_APHSP  (Q9NFL5    ), 
HCYG_APHSP  (Q9NFL4    ), HCYG_ENTDO  (O61363    ), HCYG_HELPO  (P56823    ), 
HCYG_SEPOF  (P56826    ), HCYX_SCUCO  (Q8T116    ), HCY_PALVU   (P80888    ), 
IVOB_EMENI  (Q5BGU9    ), LAHY_LARTR  (Q6UIL3    ), ORSC_EMENI  (Q5AUW8    ), 
PHCY1_HOMAM (Q6KF82    ), PHCY2_HOMAM (Q6KF81    ), PPO1_AGABI  (Q00024    ), 
PPO1_HOLDI  (Q8I6K1    ), PPO2_AGABI  (O42713    ), PPO2_DROME  (Q9V521    ), 
PPO2_HOLDI  (Q8I6K2    ), PPO3_AGABI  (C7FF04    ), PPO3_DROER  (Q8I1F6    ), 
PPO3_DROME  (Q9W1V6    ), PPO4_AGABI  (C7FF05    ), PPOA_SOLLC  (Q08303    ), 
PPOB_SOLLC  (Q08304    ), PPOB_SOLTU  (Q06355    ), PPOC_SOLLC  (Q08305    ), 
PPOD_SOLLC  (Q08306    ), PPOE_SOLLC  (Q08307    ), PPOF_SOLLC  (Q08296    ), 
PPO_MALDO   (P43309    ), PPO_PRUAR   (O81103    ), PPO_SPIOL   (P43310    ), 
PPO_VICFA   (Q06215    ), PPO_VITVI   (P43311    ), PRP1_BOMMO  (Q27451    ), 
PRP1_MANSE  (O44249    ), PRP1_SIMDA  (P85046    ), PRP2_BOMMO  (Q27452    ), 
PRP2_MANSE  (Q25519    ), TYR1_CAEEL  (P34269    ), TYR3_CAEEL  (Q19673    ), 
TYRO1_PINMG (H2A0L0    ), TYRO2_PINMG (H2A0L1    ), TYRO_ASPFU  (Q8J130    ), 
TYRO_ASPOR  (Q00234    ), TYRO_BOVIN  (Q8MIU0    ), TYRO_CANLF  (P54834    ), 
TYRO_CHICK  (P55024    ), TYRO_GORGO  (Q9BDE0    ), TYRO_HUMAN  (P14679    ), 
TYRO_MOUSE  (P11344    ), TYRO_NEUCR  (P00440    ), TYRO_ORYLA  (P55025    ), 
TYRO_PELES  (Q0MVP0    ), TYRO_PELNI  (Q04604    ), TYRO_PHONA  (A7BHQ9    ), 
TYRO_PINMA  (P86952    ), TYRO_PODAS  (Q92396    ), TYRO_RHIML  (P33180    ), 
TYRO_STRAT  (P07524    ), TYRO_STRGA  (P06845    ), TYRO_STRLN  (P55023    ), 
TYRP1_AMBME (P55027    ), TYRP1_BOVIN (Q8WN57    ), TYRP1_CARAU (P55028    ), 
TYRP1_CHICK (O57405    ), TYRP1_HUMAN (P17643    ), TYRP1_MOUSE (P07147    ), 
TYRP2_BOVIN (Q95119    ), TYRP2_CHICK (O93505    ), TYRP2_HUMAN (P40126    ), 
TYRP2_MOUSE (P29812    ), TYRP2_PIG   (Q4R1H1    ), TYRP_ASPTE  (A0A336U966), 
TYRP_ASPTN  (Q0CRX0    ), USTQ_ASPFN  (B8NM74    )
» more

UniProtKB/Swiss-Prot
False negative sequences
1 sequence

TYRO_STRGB  (P55022    )

		
UniProtKB/Swiss-Prot
'Partial' sequences
35 sequences

HCY1_HOMAM  (P82296    ), HCY1_LIODE  (P84461    ), HCY1_MAJSQ  (P82302    ), 
HCY1_NECPU  (P84846    ), HCY2_HOMAM  (P82297    ), HCY2_LIODE  (P84462    ), 
HCY2_MAJSQ  (P82303    ), HCY2_PANJA  (P82312    ), HCY3_HOMAM  (P82298    ), 
HCY3_MAJSQ  (P82304    ), HCY3_PANJA  (P82313    ), HCY4E_MAJSQ (P82306    ), 
HCY4_CARMA  (P82309    ), HCY4_HOMAM  (P82299    ), HCY4_MAJSQ  (P82305    ), 
HCY5_HOMAM  (P82300    ), HCY5_MAJSQ  (P82307    ), HCY6_HOMAM  (P82301    ), 
HCY6_MAJSQ  (P82308    ), HCYA_CONCC  (P84619    ), HCYB_CONCC  (P84620    ), 
HCYC_SEPOF  (P56824    ), HCYE_SEPOF  (P56825    ), HCYIA_PANJA (P82310    ), 
HCYIB_PANJA (P82311    ), LEC_PENST   (P84821    ), PHCY_LIODE  (P84460    ), 
PHCY_LIOHO  (P84768    ), PHCY_LIOMA  (P84769    ), PHCY_NECPU  (P84847    ), 
PPO3_SARAR  (C0HJM0    ), PPO_ZINOF   (P85026    ), TYRO_COTJA  (Q08410    ), 
TYRO_FELCA  (P55033    ), TYRO_PELSI  (P55026    )
» more

UniProtKB/Swiss-Prot
False positive sequences
5 sequences

3HID1_ARATH (Q9SZE1    ), 5053R_ASFB7 (Q89642    ), 5053R_ASFM2 (Q65129    ), 
5053R_ASFP4 (P0C9T0    ), 5053R_ASFWA (P0C9T1    )
» more

PDB
[Detailed view]
27 PDB

1HC1; 1HCY; 1JS8; 1LL1; 1LLA; 1LNL; 1NOL; 1OXY; 2P3X; 2Y9W; 2Y9X; 3HHS; 3IXV; 3IXW; 5M6B; 5M8L; 5M8M; 5M8N; 5M8O; 5M8P; 5M8Q; 5M8R; 5M8S; 5M8T; 6ELS; 6HQI; 6HQJ
» more

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