PROSITE entry PS00502

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PURL: https://purl.expasy.org/prosite/signature/PS00502

Direct ScanProsite submission

General information about the entry

Entry name [info]	POLYGALACTURONASE
Accession [info]	PS00502
Entry type [info]	PATTERN
Date [info]	01-MAY-1991 CREATED; 01-NOV-1997 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00415
Associated ProRule [info]	PRU10052

Name and characterization of the entry

Description [info]	Polygalacturonase active site.
Pattern [info]	[GSDENKRH]-x(2)-[VMFC]-x(2)-[GS]-H-G-[LIVMAG]-x(1,2)-[LIVM]-G-S.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.

Total number of hits	108 in 108 different sequences
Number of true positive hits	108 in 108 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	54
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	66.67 %

Comments [info]

Taxonomic range [info]	Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Site [info]	active_site at position 6
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

108 sequences

ADPG1_ARATH (O23147), ADPG2_ARATH (Q8RY29), PEHX_DICCH  (P15922),

PGLR1_ARATH (P49062), PGLR1_ASPAC (O74213), PGLR1_ASPCL (A1CIV8), 
PGLR1_ASPFN (B8N8M2), PGLR1_ASPNC (A2QAH3), PGLR1_ASPNG (P26213), 
PGLR1_ASPOR (Q2UHL4), PGLR1_ASPTN (Q0CMU3), PGLR1_COLLN (Q00446), 
PGLR1_MAIZE (P26216), PGLR1_PECCC (P18192), PGLR1_PENOL (Q9Y834), 
PGLR1_SCLSC (Q12708), PGLR2_ARATH (P49063), PGLR2_ASPAC (Q70HJ4), 
PGLR2_ASPAW (Q9P359), PGLR2_ASPKW (Q8NK98), PGLR2_ASPNA (P26214), 
PGLR2_ASPNC (A2R5S4), PGLR2_ASPNG (P0CU55), PGLR2_ASPTU (P0CU54), 
PGLR2_CHAOB (Q7M1E7), PGLR2_CRYJA (P43212), PGLR2_JUNAS (Q9FY19), 
PGLR2_MAIZE (P35338), PGLR2_PECPM (P26509), PGLR2_PENOL (Q9Y833), 
PGLR3_ARATH (Q9LW07), PGLR3_MAIZE (P35339), PGLR4_ARATH (Q949Z1), 
PGLR5_ARATH (Q94AJ5), PGLRA_ASPAW (Q9P358), PGLRA_ASPFA (P41749), 
PGLRA_ASPFC (B0Y4Z4), PGLRA_ASPFU (Q4WQT2), PGLRA_ASPKW (Q8NK99), 
PGLRA_ASPNC (A2R8F8), PGLRA_ASPNG (Q9P4W4), PGLRA_ASPPA (P49575), 
PGLRA_NEOFI (A1CVV8), PGLRB_ASPFA (P41750), PGLRB_ASPFC (B0YAH0), 
PGLRB_ASPFN (B8N7Z8), PGLRB_ASPFU (Q4WBE1), PGLRB_ASPKA (Q1HAY5), 
PGLRB_ASPNC (A2QCV8), PGLRB_ASPNG (Q9P4W3), PGLRB_ASPOR (P35335), 
PGLRB_EMENI (Q5B508), PGLRB_NEOFI (A1DAQ2), PGLRD_ASPFN (B8MW78), 
PGLRD_ASPNC (A2QTU0), PGLRD_ASPNG (Q9P4W2), PGLRD_ASPOR (Q2UT29), 
PGLRD_EMENI (Q5AYH4), PGLRD_NEOFI (A1DBR6), PGLRE_ASPNC (A2QBB6), 
PGLRE_ASPNG (O42809), PGLRX_ASPFC (B0YDE8), PGLRX_ASPFN (B8NG16), 
PGLRX_ASPFU (Q4WCZ8), PGLRX_ASPNC (A2R060), PGLRX_ASPNG (Q27UB3), 
PGLRX_ASPTN (Q0CGP0), PGLRX_ASPTU (Q00293), PGLRX_COCCA (Q00359), 
PGLRX_NEOFI (A1DLC1), PGLR_ACTDE  (P35336), PGLR_ASPFC  (B0XPA1), 
PGLR_ASPFU  (Q4WR80), PGLR_BRANA  (P35337), PGLR_COCCA  (P26215), 
PGLR_CUPSE  (C0HKB1), PGLR_EMENI  (Q5ATQ3), PGLR_FUSFU  (Q07181), 
PGLR_GOSBA  (Q39766), PGLR_GOSHI  (Q39786), PGLR_MALDO  (P48978), 
PGLR_MEDSA  (Q40312), PGLR_NEOFI  (A1D145), PGLR_OENOR  (P24548), 
PGLR_PENDI  (Q9Y718), PGLR_PENEN  (O59925), PGLR_PENGR  (O93883), 
PGLR_PENJA  (O42824), PGLR_PERAE  (Q02096), PGLR_PRUPE  (P48979), 
PGLR_RALN1  (P58598), PGLR_RALSL  (P20041), PGLR_RHIRD  (P27644), 
PGLR_SOLLC  (P05117), PGLR_TOBAC  (Q05967), PGLR_YEAST  (P47180), 
PGLX1_EMENI (Q5ASG9), PGLX2_EMENI (Q5ARN5), PGXA_ASPNC  (A2QW66), 
PGXA_ASPNG  (Q27UB2), QRT2_ARATH  (Q9SFB7), SALK6_KALTU (W8P8Q3), 
XGHA_ASPFC  (B0Y9F8), XGHA_ASPFN  (B8NPS8), XGHA_ASPFU  (Q4WBT4), 
XGHA_ASPOR  (Q2UBD8), XGHA_EMENI  (Q5B7U1), XGHA_NEOFI  (A1DBT5)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

54 sequences

PGLR2_PLAAC (Q6H9K0), PGLR6_ARATH (O22818), PGLRC_ASPAC (Q70HJ3),

PGLRC_ASPNC (A2QL39), PGLRC_ASPNG (Q12554), PGLR_PHACE  (O97400), 
PGLR_VITVI  (A7PZL3), PGXB_ASPFC  (B0YAA4), PGXB_ASPFN  (B8NX60), 
PGXB_ASPFU  (Q4WBK6), PGXB_ASPNC  (A2QHG0), PGXB_ASPNG  (Q27UB1), 
PGXB_ASPOR  (Q2TW03), PGXB_ASPTN  (Q0C7H7), PGXB_EMENI  (Q873X6), 
PGXB_NEOFI  (A1DAX2), PGXC_ASPFC  (B0XYC4), PGXC_ASPFN  (B8MZZ6), 
PGXC_ASPFU  (Q4WX94), PGXC_ASPNC  (A2QEW2), PGXC_ASPNG  (Q27UB0), 
PGXC_ASPOR  (Q2UQ40), PGXC_ASPTN  (Q0CXI3), PGXC_NEOFI  (A1D7I1), 
RGXA_ASPFN  (B8NJB0), RGXA_ASPNC  (A2QBB4), RGXA_ASPNG  (Q2EQQ2), 
RGXA_ASPOR  (Q2UP32), RGXB_ASPNC  (A2QG68), RGXC_ASPNC  (A2RAY7), 
RGXC_NEOFI  (A1D415), RHGA_ASPAC  (Q00001), RHGA_ASPFN  (B8NK45), 
RHGA_ASPNC  (A2QYE5), RHGA_ASPNG  (P87160), RHGA_ASPOR  (Q2U293), 
RHGA_EMENI  (Q5ARE6), RHGB_ASPFC  (B0Y0Q3), RHGB_ASPFU  (Q4WV23), 
RHGB_ASPNC  (A2R3G4), RHGB_ASPNG  (P87161), RHGB_ASPOR  (Q2TWN8), 
RHGB_ASPTN  (Q0CFC7), RHGB_NEOFI  (A1DED1), RHGC_ASPFN  (B8NGP8), 
RHGC_ASPNC  (A2QLQ5), RHGC_ASPOR  (Q2UFD2), RHGD_ASPNC  (A2QWT2), 
RHGE_ASPFN  (B8NKB9), RHGE_ASPNC  (A2QXE8), RHGE_ASPNG  (Q1ZZM3), 
RHGE_ASPOR  (Q2U7A4), XGHA_ASPNC  (A2QK83), XGHA_ASPTU  (Q9UUZ2)

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PDB
[Detailed view]

7 PDB

1BHE; 1CZF; 1HG8; 1IA5; 1IB4; 1NHC; 7B8B