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PROSITE entry PS00512


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00512
Entry name [info] ALPHA_GALACTOSIDASE
Accession [info] PS00512
Entry type [info] PATTERN
Date [info] 01-JUN-1991 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00443

Name and characterization of the entry

Description [info] Alpha-galactosidase signature.
Pattern [info] 
G-[LIVMFY]-x(2)-[LIVMFY]-x-[LIVM]-D-[DF]-x(1,2)-W-x(3,7)-[RV]-[DNSF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 51 in 51 different sequences
Number of true positive hits 49 in 49 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 22
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 96.08 %
Recall (true positives / (true positives + false negatives)) 69.01 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 49 sequences 

AGAA_GEOSE  (Q9ALJ4), AGAL1_ARATH (Q9FT97), AGAL1_PEDPE (P43467), 

AGAL2_ARATH (Q8RX86), AGAL2_HYPJE (Q92457), AGAL2_PEDPE (P43469), 
AGAL3_ARATH (Q8VXZ7), AGALA_ASPNC (A2QL72), AGALA_ASPNG (P28351), 
AGALB_ASPCL (A1C5D3), AGALB_ASPFC (B0Y224), AGALB_ASPFN (B8N306), 
AGALB_ASPFU (Q4WE86), AGALB_ASPNC (A2QEJ9), AGALB_ASPNG (Q9Y865), 
AGALB_ASPOR (Q2UJ97), AGALB_EMENI (Q5AVQ6), AGALB_NEOFI (A1D0A3), 
AGALB_PENSI (O94221), AGALB_TALEM (A7XZT2), AGALC_ASPFN (B8NWY6), 
AGALC_ASPNG (Q9UUZ4), AGALC_ASPOR (Q2TW69), AGAL_CELJU  (B3PGJ1), 
AGAL_COFAR  (Q42656), AGAL_CYATE  (P14749), AGAL_HUMAN  (P06280), 
AGAL_MOUSE  (P51569), AGAL_ORYSJ  (Q9FXT4), AGAL_SCHPO  (Q9URZ0), 
AGAL_STRMU  (P27756), AGASK_MEDGN (G4T4R7), IMD_ARTGO   (Q44052), 
MEL1_YEASX  (P04824), MEL2_YEASX  (P41945), MEL5_YEASX  (P41946), 
MEL6_YEASX  (P41947), MELA_LACAC  (G1UB44), MEL_LACCI   (Q99172), 
MEL_SACMI   (Q11129), MEL_SACPA   (Q09187), MEL_TORDE   (Q9UVD6), 
MEL_ZYGMR   (Q9P4V4), NAGAB_BOVIN (Q58DH9), NAGAB_CHICK (Q90744), 
NAGAB_HUMAN (P17050), NAGAB_MOUSE (Q9QWR8), NAGAB_RAT   (Q66H12), 
RAFA_ECOLX  (P16551)
» more

UniProtKB/Swiss-Prot
False negative sequences		 22 sequences 

AGAL3_HYPJE (Q92451), AGAL8_EMENI (C8VJZ7), AGALA_ASPCL (A1CBW8), 

AGALA_ASPFN (B8MWJ5), AGALA_ASPFU (Q4WVZ3), AGALA_ASPOR (Q2UT06), 
AGALA_ASPTN (Q0CPK2), AGALA_NEOFI (A1DDD8), AGALC_ASPTN (Q0CVH2), 
AGALC_EMENI (Q5AU92), AGALD_ASPFC (B0YEK2), AGALD_ASPFN (B8N7Z0), 
AGALD_ASPFU (A4DA70), AGALD_ASPNC (A2R2S6), AGALD_ASPOR (Q2UI87), 
AGALD_ASPTN (Q0CVX4), AGALD_EMENI (Q5AX28), AGALD_NEOFI (A1D9S3), 
AGALG_ASPTN (Q0CEF5), AGALG_EMENI (Q5ARP5), AGAL_THEMA  (G4FEF4), 
MEL_SACCA   (Q03647)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 2 sequences 

AGAL_CAPAA  (P86073), NAGAB_BOSIN (P83127)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			2 sequences
			


			
POXI_PENO1  (S8B3I4), POXI_PENOX  (A0A1W5T323)


				
	

	

		PDB
[Detailed view]		
		
			54 PDB
			


			1KTB; 1KTC; 1R46; 1R47; 1UAS; 2XN0; 2XN1; 2XN2; 2YFN; 2YFO; 3GXN; 3GXP; 
			
				3GXT; 3H53; 3H54; 3H55; 3HG2; 3HG3; 3HG4; 3HG5; 3IGU; 3LRK; 3LRL; 3LRM; 
				3LX9; 3LXA; 3LXB; 3LXC; 3S5Y; 3S5Z; 3TV8; 4DO4; 4DO5; 4DO6; 4FNP; 4FNR; 
				4FNS; 4FNT; 4FNU; 4NXS; 6IBK; 6IBM; 6IBR; 6IBT; 8K7D; 8K7E; 8K7F; 8K7G; 
				8K7H; 8K7I; 8K7J; 8K7K; 8K7L; 9AVS
			
			

			» more