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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS00522


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PURL: https://purl.expasy.org/prosite/signature/PS00522

Direct ScanProsite submission
General information about the entry

Entry name [info] DNA_POLYMERASE_X
Accession [info] PS00522
Entry type [info] PATTERN
Date [info] 01-DEC-1991 CREATED;
01-NOV-1995 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00452

Name and characterization of the entry

Description [info] DNA polymerase family X signature.
Pattern [info] 
G-[SG]-[LFY]-x-R-[GE]-x(3)-[SGCL]-x-D-[LIVM]-D-[LIVMFY](3)-x(2)-[SAP].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 31 in 31 different sequences
Number of true positive hits 31 in 31 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 1
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 96.88 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] primer_binding at position 5
Site [info] primer_binding at position 10
Site [info] primer_binding at position 12
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 31 sequences 

DPO4_SCHPO  (Q09693), DPO4_YEAST  (P25615), DPOLB_BOVIN (Q27958), 

DPOLB_DANRE (Q6DRD3), DPOLB_HUMAN (P06746), DPOLB_MOUSE (Q8K409), 
DPOLB_RAT   (P06766), DPOLB_XENLA (O57383), DPOLL_ARATH (Q9FNY4), 
DPOLL_HUMAN (Q9UGP5), DPOLL_MACFA (Q4R380), DPOLL_MOUSE (Q9QXE2), 
DPOLL_ORYSJ (Q67VC8), DPOLL_RAT   (Q5RKI3), DPOLM_HUMAN (Q9NP87), 
DPOLM_MOUSE (Q9JIW4), DPOLX_ASFB7 (P42494), DPOLX_ASFK5 (P0C986), 
DPOLX_ASFM2 (P0C984), DPOLX_ASFP4 (P0C983), DPOLX_ASFWA (P0C985), 
DPOLX_MIMIV (Q7T6Y4), TDT_AMBME   (O57486), TDT_BOVIN   (P06526), 
TDT_CHICK   (P36195), TDT_EULMA   (A4PCD4), TDT_HUMAN   (P04053), 
TDT_MONDO   (O02789), TDT_MOUSE   (P09838), TDT_ONCMY   (Q92089), 
TDT_XENLA   (P42118)
» more

UniProtKB/Swiss-Prot
False negative sequences		 1 sequence 

POLX_BACSU  (P94544)


				
	

	

		PDB
[Detailed view]		
		
			714 PDB
			


			pdb_00001bpb; pdb_00001bpd; pdb_00001bpe; pdb_00001bpx; pdb_00001bpy; pdb_00001bpz; pdb_00001huo; pdb_00001huz; pdb_00001jaj; pdb_00001jms; pdb_00001jn3; pdb_00001jqr; 
			
				pdb_00001kdh; pdb_00001kej; pdb_00001mq2; pdb_00001mq3; pdb_00001nom; pdb_00001rpl; pdb_00001rzt; pdb_00001tv9; pdb_00001tva; pdb_00001xsl; pdb_00001xsn; pdb_00001xsp; 
				pdb_00001zjm; pdb_00001zjn; pdb_00001zqa; pdb_00001zqb; pdb_00001zqc; pdb_00001zqd; pdb_00001zqe; pdb_00001zqf; pdb_00001zqg; pdb_00001zqh; pdb_00001zqi; pdb_00001zqj; 
				pdb_00001zqk; pdb_00001zql; pdb_00001zqm; pdb_00001zqn; pdb_00001zqo; pdb_00001zqp; pdb_00001zqq; pdb_00001zqr; pdb_00001zqs; pdb_00001zqt; pdb_00001zqu; pdb_00001zqv; 
				pdb_00001zqw; pdb_00001zqx; pdb_00001zqy; pdb_00001zqz; pdb_00002bcq; pdb_00002bcr; pdb_00002bcs; pdb_00002bcu; pdb_00002bcv; pdb_00002bpc; pdb_00002bpf; pdb_00002bpg; 
				pdb_00002fmp; pdb_00002fmq; pdb_00002fms; pdb_00002gws; pdb_00002i9g; pdb_00002ihm; pdb_00002iso; pdb_00002isp; pdb_00002m2t; pdb_00002m2u; pdb_00002m2v; pdb_00002m2w; 
				pdb_00002p66; pdb_00002pfn; pdb_00002pfo; pdb_00002pfp; pdb_00002pfq; pdb_00002pxi; pdb_00002van; pdb_00003c2k; pdb_00003c2l; pdb_00003c2m; pdb_00003c5f; pdb_00003c5g; 
				pdb_00003gdx; pdb_00003hw8; pdb_00003hwt; pdb_00003hx0; pdb_00003isb; pdb_00003isc; pdb_00003isd; pdb_00003jpn; pdb_00003jpo; pdb_00003jpp; pdb_00003jpq; pdb_00003jpr; 
				pdb_00003jps; pdb_00003jpt; pdb_00003k75; pdb_00003lk9; pdb_00003lqc; pdb_00003mby; pdb_00003mda; pdb_00003mdc; pdb_00003mgh; pdb_00003mgi; pdb_00003ogu; pdb_00003pml; 
				pdb_00003pmn; pdb_00003pnc; pdb_00003rh4; pdb_00003rh5; pdb_00003rh6; pdb_00003rje; pdb_00003rjf; pdb_00003rjg; pdb_00003rjh; pdb_00003rji; pdb_00003rjj; pdb_00003rjk; 
				pdb_00003tfr; pdb_00003tfs; pdb_00003upq; pdb_00003uq0; pdb_00003uq2; pdb_00003uxn; pdb_00003uxo; pdb_00003uxp; pdb_00003v72; pdb_00003v7j; pdb_00003v7k; pdb_00003v7l; 
				pdb_00004do9; pdb_00004doa; pdb_00004dob; pdb_00004doc; pdb_00004f5n; pdb_00004f5o; pdb_00004f5p; pdb_00004f5q; pdb_00004f5r; pdb_00004fo6; pdb_00004gxi; pdb_00004gxj; 
				pdb_00004gxk; pdb_00004i27; pdb_00004i28; pdb_00004i29; pdb_00004i2a; pdb_00004i2b; pdb_00004i2c; pdb_00004i2d; pdb_00004i2e; pdb_00004i2f; pdb_00004i2g; pdb_00004i2h; 
				pdb_00004i2i; pdb_00004i2j; pdb_00004iqt; pdb_00004iqu; pdb_00004iqv; pdb_00004iqw; pdb_00004jwm; pdb_00004jwn; pdb_00004k4g; pdb_00004k4h; pdb_00004k4i; pdb_00004kld; 
				pdb_00004kle; pdb_00004klf; pdb_00004klg; pdb_00004klh; pdb_00004kli; pdb_00004klj; pdb_00004kll; pdb_00004klm; pdb_00004klo; pdb_00004klq; pdb_00004kls; pdb_00004klt; 
				pdb_00004klu; pdb_00004lvs; pdb_00004lzd; pdb_00004lzg; pdb_00004m04; pdb_00004m0a; pdb_00004m2y; pdb_00004m47; pdb_00004m9g; pdb_00004m9h; pdb_00004m9j; pdb_00004m9l; 
				pdb_00004m9n; pdb_00004mf2; pdb_00004mf8; pdb_00004mfa; pdb_00004mfc; pdb_00004mff; pdb_00004nlk; pdb_00004nln; pdb_00004nlz; pdb_00004nm1; pdb_00004nm2; pdb_00004nxz; 
				pdb_00004ny8; pdb_00004o5c; pdb_00004o5e; pdb_00004o5k; pdb_00004o9m; pdb_00004p2h; pdb_00004pgq; pdb_00004pgx; pdb_00004pgy; pdb_00004ph5; pdb_00004pha; pdb_00004phd; 
				pdb_00004phe; pdb_00004php; pdb_00004ppx; pdb_00004qz8; pdb_00004qz9; pdb_00004qza; pdb_00004qzb; pdb_00004qzc; pdb_00004qzd; pdb_00004qze; pdb_00004qzf; pdb_00004qzg; 
				pdb_00004qzh; pdb_00004qzi; pdb_00004r63; pdb_00004r64; pdb_00004r65; pdb_00004r66; pdb_00004rpx; pdb_00004rpy; pdb_00004rpz; pdb_00004rq0; pdb_00004rq1; pdb_00004rq2; 
				pdb_00004rq3; pdb_00004rq4; pdb_00004rq5; pdb_00004rq6; pdb_00004rq7; pdb_00004rq8; pdb_00004rt2; pdb_00004rt3; pdb_00004tup; pdb_00004tuq; pdb_00004tur; pdb_00004tus; 
				pdb_00004uaw; pdb_00004uay; pdb_00004uaz; pdb_00004ub1; pdb_00004ub2; pdb_00004ub3; pdb_00004ub4; pdb_00004ub5; pdb_00004ubb; pdb_00004ubc; pdb_00004x5v; pdb_00004xa5; 
				pdb_00004xq8; pdb_00004xrh; pdb_00004xus; pdb_00004ycx; pdb_00004yd1; pdb_00004yd2; pdb_00004ymm; pdb_00004ymn; pdb_00004ymo; pdb_00004yn4; pdb_00004z6c; pdb_00004z6d; 
				pdb_00004z6e; pdb_00004z6f; pdb_00005bol; pdb_00005bom; pdb_00005bpc; pdb_00005ca7; pdb_00005cb1; pdb_00005d46; pdb_00005d49; pdb_00005d4b; pdb_00005db6; pdb_00005db7; 
				pdb_00005db8; pdb_00005db9; pdb_00005dba; pdb_00005dbb; pdb_00005dbc; pdb_00005ddm; pdb_00005ddy; pdb_00005dkw; pdb_00005eoz; pdb_00005hhh; pdb_00005hhi; pdb_00005hr9; 
				pdb_00005hrb; pdb_00005hrd; pdb_00005hre; pdb_00005hrf; pdb_00005hrh; pdb_00005hri; pdb_00005hrk; pdb_00005hrl; pdb_00005iii; pdb_00005iij; pdb_00005iik; pdb_00005iil; 
				pdb_00005iim; pdb_00005iin; pdb_00005iio; pdb_00005j0o; pdb_00005j0p; pdb_00005j0q; pdb_00005j0r; pdb_00005j0s; pdb_00005j0t; pdb_00005j0u; pdb_00005j0w; pdb_00005j0x; 
				pdb_00005j0y; pdb_00005j29; pdb_00005j2a; pdb_00005j2b; pdb_00005j2c; pdb_00005j2d; pdb_00005j2e; pdb_00005j2f; pdb_00005j2g; pdb_00005j2h; pdb_00005j2i; pdb_00005j2j; 
				pdb_00005j2k; pdb_00005tb8; pdb_00005tb9; pdb_00005tba; pdb_00005tbb; pdb_00005tbc; pdb_00005twp; pdb_00005twq; pdb_00005twr; pdb_00005tws; pdb_00005txx; pdb_00005txz; 
				pdb_00005tyb; pdb_00005tyc; pdb_00005tyd; pdb_00005tye; pdb_00005tyf; pdb_00005tyg; pdb_00005tyu; pdb_00005tyv; pdb_00005tyw; pdb_00005tyx; pdb_00005tyy; pdb_00005tyz; 
				pdb_00005tzv; pdb_00005u2r; pdb_00005u2s; pdb_00005u2t; pdb_00005u8g; pdb_00005u8h; pdb_00005u8i; pdb_00005u9h; pdb_00005ugn; pdb_00005ugo; pdb_00005ugp; pdb_00005v1f; 
				pdb_00005v1g; pdb_00005v1h; pdb_00005v1i; pdb_00005v1j; pdb_00005v1n; pdb_00005v1o; pdb_00005v1p; pdb_00005v1r; pdb_00005vez; pdb_00005vrw; pdb_00005vrx; pdb_00005vry; 
				pdb_00005vrz; pdb_00005vs0; pdb_00005vs1; pdb_00005vs2; pdb_00005vs3; pdb_00005vs4; pdb_00005vz7; pdb_00005vz8; pdb_00005vz9; pdb_00005vza; pdb_00005vzb; pdb_00005vzc; 
				pdb_00005vzd; pdb_00005vze; pdb_00005vzf; pdb_00005vzg; pdb_00005vzh; pdb_00005vzi; pdb_00005wnx; pdb_00005wny; pdb_00005wnz; pdb_00005wo0; pdb_00005xm8; pdb_00005xma; 
				pdb_00005zlc; pdb_00006aec; pdb_00006aeh; pdb_00006ak5; pdb_00006ak6; pdb_00006ak8; pdb_00006ak9; pdb_00006akh; pdb_00006bel; pdb_00006bem; pdb_00006bte; pdb_00006btf; 
				pdb_00006cly; pdb_00006cpq; pdb_00006cr3; pdb_00006cr4; pdb_00006cr5; pdb_00006cr6; pdb_00006cr7; pdb_00006cr8; pdb_00006cr9; pdb_00006crb; pdb_00006crc; pdb_00006crh; 
				pdb_00006cti; pdb_00006ctj; pdb_00006ctk; pdb_00006ctl; pdb_00006ctm; pdb_00006ctn; pdb_00006cto; pdb_00006ctp; pdb_00006ctq; pdb_00006ctr; pdb_00006ctt; pdb_00006ctu; 
				pdb_00006ctv; pdb_00006ctw; pdb_00006ctx; pdb_00006cu9; pdb_00006cua; pdb_00006cub; pdb_00006dia; pdb_00006dic; pdb_00006e3r; pdb_00006e3v; pdb_00006e3w; pdb_00006e3x; 
				pdb_00006g2q; pdb_00006go3; pdb_00006go4; pdb_00006go5; pdb_00006go6; pdb_00006go7; pdb_00006ipd; pdb_00006ipe; pdb_00006ipf; pdb_00006ipg; pdb_00006iph; pdb_00006ipi; 
				pdb_00006ipj; pdb_00006ipk; pdb_00006ipl; pdb_00006ipm; pdb_00006ipn; pdb_00006mr7; pdb_00006mr8; pdb_00006n2r; pdb_00006n2s; pdb_00006n2t; pdb_00006nkr; pdb_00006nks; 
				pdb_00006nkt; pdb_00006nku; pdb_00006nkv; pdb_00006nkw; pdb_00006nkx; pdb_00006nky; pdb_00006nkz; pdb_00006nl0; pdb_00006p1m; pdb_00006p1n; pdb_00006p1o; pdb_00006p1p; 
				pdb_00006p1q; pdb_00006p1r; pdb_00006p1s; pdb_00006p1t; pdb_00006p1u; pdb_00006p1v; pdb_00006p1w; pdb_00006ph5; pdb_00006ph6; pdb_00006pkz; pdb_00006u2o; pdb_00006u6b; 
				pdb_00006uok; pdb_00006uol; pdb_00006uom; pdb_00006vez; pdb_00006vf0; pdb_00006vf1; pdb_00006vf2; pdb_00006vf3; pdb_00006vf4; pdb_00006vf5; pdb_00006vf6; pdb_00006vf7; 
				pdb_00006vf8; pdb_00006vf9; pdb_00006vfa; pdb_00006vfb; pdb_00006vfc; pdb_00006w2m; pdb_00006wic; pdb_00006wid; pdb_00006wie; pdb_00007co6; pdb_00007co8; pdb_00007co9; 
				pdb_00007coa; pdb_00007cob; pdb_00007coc; pdb_00007cod; pdb_00007cpw; pdb_00007ice; pdb_00007icf; pdb_00007icg; pdb_00007ich; pdb_00007ici; pdb_00007icj; pdb_00007ick; 
				pdb_00007icl; pdb_00007icm; pdb_00007icn; pdb_00007ico; pdb_00007icp; pdb_00007icq; pdb_00007icr; pdb_00007ics; pdb_00007ict; pdb_00007icu; pdb_00007icv; pdb_00007k96; 
				pdb_00007k97; pdb_00007kss; pdb_00007kst; pdb_00007ksu; pdb_00007ksv; pdb_00007ksw; pdb_00007ksx; pdb_00007ksy; pdb_00007ksz; pdb_00007kt0; pdb_00007kt1; pdb_00007kt2; 
				pdb_00007kt3; pdb_00007kt4; pdb_00007kt5; pdb_00007kt6; pdb_00007kt7; pdb_00007kt8; pdb_00007kt9; pdb_00007kta; pdb_00007ktb; pdb_00007ktc; pdb_00007ktd; pdb_00007kte; 
				pdb_00007ktf; pdb_00007ktg; pdb_00007kth; pdb_00007kti; pdb_00007ktj; pdb_00007ktk; pdb_00007ktl; pdb_00007ktm; pdb_00007ktn; pdb_00007m07; pdb_00007m08; pdb_00007m09; 
				pdb_00007m0a; pdb_00007m0b; pdb_00007m0c; pdb_00007m0d; pdb_00007m0e; pdb_00007m43; pdb_00007m44; pdb_00007m45; pdb_00007m46; pdb_00007m47; pdb_00007m48; pdb_00007m49; 
				pdb_00007m4a; pdb_00007m4b; pdb_00007m4c; pdb_00007m4d; pdb_00007m4e; pdb_00007m4f; pdb_00007m4g; pdb_00007m4h; pdb_00007m4i; pdb_00007m4j; pdb_00007m4k; pdb_00007m4l; 
				pdb_00007mz0; pdb_00007mz1; pdb_00007mz2; pdb_00007mz3; pdb_00007mz4; pdb_00007mz8; pdb_00007rbe; pdb_00007rbf; pdb_00007rbg; pdb_00007rbh; pdb_00007rbi; pdb_00007rbj; 
				pdb_00007rbk; pdb_00007rbl; pdb_00007rbm; pdb_00007rbn; pdb_00007rbo; pdb_00007s9j; pdb_00007s9k; pdb_00007s9l; pdb_00007s9m; pdb_00007s9n; pdb_00007s9o; pdb_00007s9p; 
				pdb_00007s9q; pdb_00007un7; pdb_00008e10; pdb_00008e11; pdb_00008e9a; pdb_00008ica; pdb_00008icb; pdb_00008icc; pdb_00008ice; pdb_00008icf; pdb_00008icg; pdb_00008ich; 
				pdb_00008ici; pdb_00008icj; pdb_00008ick; pdb_00008icl; pdb_00008icm; pdb_00008icn; pdb_00008ico; pdb_00008icp; pdb_00008icq; pdb_00008icr; pdb_00008ics; pdb_00008ict; 
				pdb_00008icu; pdb_00008icv; pdb_00008icw; pdb_00008icx; pdb_00008icy; pdb_00008icz; pdb_00008ild; pdb_00008ile; pdb_00008ilf; pdb_00008ilg; pdb_00008ilh; pdb_00008ili; 
				pdb_00008u0o; pdb_00008vf8; pdb_00008vf9; pdb_00008vfa; pdb_00008vfb; pdb_00008vfc; pdb_00008vfd; pdb_00008vfe; pdb_00008vff; pdb_00008vfg; pdb_00008vfh; pdb_00008vfi; 
				pdb_00008vfj; pdb_00009dwg; pdb_00009dwh; pdb_00009dwi; pdb_00009dwk; pdb_00009dwm; pdb_00009ica; pdb_00009icb; pdb_00009icc; pdb_00009ice; pdb_00009icf; pdb_00009icg; 
				pdb_00009ich; pdb_00009ici; pdb_00009icj; pdb_00009ick; pdb_00009icl; pdb_00009icm; pdb_00009icn; pdb_00009ico; pdb_00009icp; pdb_00009icq; pdb_00009icr; pdb_00009ics; 
				pdb_00009ict; pdb_00009icu; pdb_00009icv; pdb_00009icw; pdb_00009icx; pdb_00009icy
			
			

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