PROSITE entry PS00523

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS00523
Entry name [info]	SULFATASE_1
Accession [info]	PS00523
Entry type [info]	PATTERN
Date [info]	01-DEC-1991 CREATED; 01-DEC-2004 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00117

Name and characterization of the entry

Description [info]	Sulfatases signature 1.
Pattern [info]	[SAPG]-[LIVMST]-[CS]-[STACG]-P-[STA]-R-x(2)-[LIVMFW](2)-[TAR]-G.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	62 in 62 different sequences
Number of true positive hits	61 in 61 different sequences
Number of 'unknown' hits	0
Number of false positive hits	1
Number of false negative sequences	20
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	98.39 %
Recall (true positives / (true positives + false negatives))	75.31 %

Comments [info]

Taxonomic range [info]	Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	61 sequences ARSA_BOVIN (Q08DD1), ARSA_HUMAN (P15289), ARSA_MOUSE (P50428), ARSB_FELCA (P33727), ARSB_HUMAN (P15848), ARSB_MOUSE (P50429), ARSB_RAT(P50430), ARSD_HUMAN (P51689), ARSF_HUMAN (P54793), ARSG_CANLF (Q32KH9), ARSG_HUMAN (Q96EG1), ARSG_MOUSE (Q3TYD4), ARSG_RAT(Q32KJ9), ARSH_CANLF (Q32KH8), ARSH_HUMAN (Q5FYA8), ARSI_CANLF (Q32KH7), ARSI_HUMAN (Q5FYB1), ARSI_MOUSE (Q32KI9), ARSI_RAT(Q32KJ8), ARSJ_HUMAN (Q5FYB0), ARSJ_MOUSE (Q8BM89), ARSL_HUMAN (P51690), ARSL_MACFA (Q60HH5), ARS_CHLRE (P14217), ARS_HEMPU (P14000), ARS_PSEAE (P51691), ARS_STRPU (P50473), ARS_VOLCA (Q10723), ASLA_ECOLI (P25549), ATSA_KLEAE (P20713), ATSA_KLEPN (Q9X759), BETC_RHIME (O69787), GALNS_CANLF (Q32KH5), GALNS_HUMAN (P34059), GALNS_MOUSE (Q571E4), GALNS_PIG (Q8WNQ7), GALNS_RAT (Q32KJ6), GALSF_BACTN (Q8A2H2), GLCSF_BACTN (Q89YS5), GNS_BOVIN (Q1LZH9), GNS_CAPHI (P50426), GNS_HUMAN (P15586), GNS_MOUSE (Q8BFR4), IDS_HUMAN (P22304), IDS_MOUSE (Q08890), PLH12_FORAG (T2KN71), PLH14_FORAG (T2KMG4), SPHM_HUMAN (P51688), STS_HUMAN (P08842), STS_MOUSE (P50427), STS_RAT (P15589), SULF1_CAEEL (Q21376), SULF1_COTCO (Q90XB6), SULF1_DROME (Q9VEX0), SULF1_HUMAN (Q8IWU6), SULF1_MOUSE (Q8K007), SULF1_RAT (Q8VI60), SULF2_HUMAN (Q8IWU5), SULF2_MOUSE (Q8CFG0), YDEN_ECOLI (P77318), YIDJ_ECOLI (P31447) » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	20 sequences AGL7_HALVD (D4GU60), ARSK_BOVIN (Q148F3), ARSK_CANLF (Q32KH0), ARSK_CHICK (Q5ZK90), ARSK_DANRE (Q08CJ7), ARSK_HUMAN (Q6UWY0), ARSK_MOUSE (Q9D2L1), ARSK_RAT(Q32KJ2), ARSK_XENLA (Q0IHJ2), ENDSF_BACTN (Q8A2F6), HEXSF_BACTN (Q8A7C8), PLH11_FORAG (T2KM04), PLH13_FORAG (T2KPJ9), PLH18_FORAG (T2KPK5), PLH19_FORAG (T2KMG7), PLH32_FORAG (T2KN90), PLH36_FORAG (T2KM26), SULF_CLOP1 (Q0TUK6), SULF_CLOPE (Q8XNV1), YHJ2_SCHPO (Q9C0V7) » more
UniProtKB/Swiss-Prot False positive sequences	1 sequence PSBP3_TOBAC (Q04127)
PDB [Detailed view]	11 PDB 1E1Z; 1E3C; 1N2K; 1N2L; 4MHX; 4MIV; 5G2V; 6FNY; 6S20; 7PTH; 7PTJ