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PROSITE entry PS00524


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00524
Entry name [info] SMB_1
Accession [info] PS00524
Entry type [info] PATTERN
Date [info] 01-DEC-1991 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00453

Name and characterization of the entry

Description [info] Somatomedin B domain (SMB) signature.
Pattern [info] 
C-x-C-x(3)-C-x(5,6)-C-C-x-[DN]-[FY]-x(3)-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 59 in 37 different sequences
Number of true positive hits 59 in 37 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 1
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 98.33 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 2
Site [info] disulfide(?) at position 1
Site [info] disulfide(?) at position 3
Site [info] disulfide(?) at position 5
Site [info] disulfide(?) at position 7
Site [info] disulfide(?) at position 8
Site [info] disulfide(?) at position 13
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 37 sequences 

ENDOU_BOVIN (A6QLQ8), ENDOU_HUMAN (P21128), ENDOU_MOUSE (Q3V188), 

ENDOU_PAROL (Q9PTU6), ENPP1_HUMAN (P22413), ENPP1_MOUSE (P06802), 
ENPP1_RAT   (Q924C3), ENPP2_BOVIN (A1A4K5), ENPP2_HUMAN (Q13822), 
ENPP2_MOUSE (Q9R1E6), ENPP2_RAT   (Q64610), ENPP3_BOVIN (P15396), 
ENPP3_HUMAN (O14638), ENPP3_MOUSE (Q6DYE8), ENPP3_PONAB (Q5R5M5), 
ENPP3_RAT   (P97675), PDE1_CROAD  (J3SEZ3), PDE2_CROAD  (J3SBP3), 
PDE_CRODO   (P0DQQ4), PDE_MACLB   (W8E7D1), PDE_NAJAT   (A0A2D0TC04), 
PRG4_HUMAN  (Q92954), PRG4_MOUSE  (Q9JM99), SBSPO_BOVIN (Q32L50), 
SBSPO_HUMAN (Q8IVN8), SBSPO_MOUSE (Q3UPR9), SUSD2_HUMAN (Q9UGT4), 
SUSD2_MOUSE (Q9DBX3), TINAG_BOVIN (Q3SZI1), TINAG_HUMAN (Q9UJW2), 
TINAL_HUMAN (Q9GZM7), TINAL_MOUSE (Q99JR5), TINAL_RAT   (Q9EQT5), 
VTNC_HUMAN  (P04004), VTNC_MOUSE  (P29788), VTNC_PIG(P48819), 
VTNC_RABIT  (P22458)
» more

UniProtKB/Swiss-Prot
False negative sequences		 1 sequence 

YCF2E_CAEEL (P90850)


				
	

	

		PDB
[Detailed view]		
		
			284 PDB
			


			1OC0; 1S4G; 1SSU; 2CQW; 2JQ8; 2XR9; 2XRG; 2YS0; 3BT1; 3BT2; 3NKM; 3NKN; 
			
				3NKO; 3NKP; 3NKQ; 3NKR; 3WAV; 3WAW; 3WAX; 3WAY; 4B56; 4GTW; 4GTX; 4GTY; 
				4GTZ; 4K24; 4ZG6; 4ZG7; 4ZG9; 4ZGA; 5DLT; 5DLV; 5DLW; 5GZ4; 5GZ5; 5HRT; 
				5IJQ; 5IJS; 5INH; 5KXA; 5L0B; 5L0E; 5L0K; 5LIA; 5LQQ; 5M0D; 5M0E; 5M0M; 
				5M0S; 5M7M; 5MHP; 5OHI; 5OLB; 5S9L; 5S9M; 5S9N; 6C01; 6C02; 6G4G; 6LEH; 
				6WET; 6WEU; 6WEV; 6WEW; 6WFJ; 6XKD; 6Y5M; 7CBA; 7G2E; 7G2F; 7G2G; 7G2H; 
				7G2I; 7G2J; 7G2K; 7G2L; 7G2M; 7G2N; 7G2O; 7G2P; 7G2Q; 7G2R; 7G2S; 7G2T; 
				7G2U; 7G2V; 7G2W; 7G2X; 7G2Y; 7G2Z; 7G30; 7G31; 7G32; 7G33; 7G34; 7G35; 
				7G36; 7G37; 7G38; 7G39; 7G3A; 7G3B; 7G3C; 7G3D; 7G3E; 7G3F; 7G3G; 7G3H; 
				7G3I; 7G3J; 7G3K; 7G3L; 7G3M; 7G3N; 7G3O; 7G3P; 7G3Q; 7G3R; 7G3S; 7G3T; 
				7G3U; 7G3V; 7G3W; 7G3X; 7G3Y; 7G3Z; 7G40; 7G41; 7G42; 7G43; 7G44; 7G45; 
				7G46; 7G47; 7G48; 7G49; 7G4A; 7G4B; 7G4C; 7G4D; 7G4E; 7G4F; 7G4G; 7G4H; 
				7G4I; 7G4J; 7G4K; 7G4L; 7G4M; 7G4N; 7G4O; 7G4P; 7G4Q; 7G4R; 7G4S; 7G4T; 
				7G4U; 7G4V; 7G4W; 7G4X; 7G4Y; 7G4Z; 7G50; 7G51; 7G52; 7G53; 7G54; 7G55; 
				7G56; 7G57; 7G58; 7G59; 7G5A; 7G5B; 7G5C; 7G5D; 7G5E; 7G5F; 7G5G; 7G5H; 
				7G5I; 7G5J; 7G5K; 7G5L; 7G5M; 7G5N; 7G5O; 7G5P; 7G5Q; 7G5R; 7G5S; 7G5T; 
				7G5U; 7G5V; 7G5W; 7G5X; 7G5Y; 7G5Z; 7G60; 7G61; 7G62; 7G63; 7G64; 7G65; 
				7G66; 7G67; 7G68; 7G69; 7G6A; 7G6B; 7G6C; 7G6D; 7G6E; 7G6F; 7G6G; 7G6H; 
				7G6I; 7G6J; 7G6K; 7G6L; 7G6M; 7G6N; 7G6O; 7G6P; 7G6Q; 7G6R; 7G6S; 7G6T; 
				7G6U; 7G6V; 7G6W; 7G6X; 7G6Y; 7G6Z; 7G70; 7G71; 7G72; 7G73; 7G74; 7G75; 
				7G76; 7G77; 7G78; 7G79; 7G7A; 7G7B; 7G7C; 7G7D; 7G7E; 7G7F; 7G7G; 7G7H; 
				7G7I; 7G7J; 7G7K; 7G7L; 7G7M; 7G7N; 7G7O; 7G7P; 7G7Q; 7G7R; 7G7S; 7G7T; 
				7G7U; 7G7V; 7G7W; 7G7X; 7G7Y; 7G7Z; 7MFH; 7P0K; 7P4J; 7P4O; 7Z0N; 7Z3K; 
				7Z3L; 8C3O; 8C3P; 8C4W; 8C7R; 9ENT; 9EU5; 9FTW
			
			

			» more