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PROSITE entry PS00533
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Direct ScanProsite submission
General information about the entry
Entry name [info] | PORPHOBILINOGEN_DEAM |
Accession [info] | PS00533 |
Entry type [info] | PATTERN |
Date [info] |
01-DEC-1991 CREATED;
01-DEC-2004 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
PROSITE Doc. [info] | PDOC00461 |
Name and characterization of the entry
Description [info] | Porphobilinogen deaminase cofactor-binding site. |
Pattern [info] |
E-[KR]-x-[LIVMFAT]-x(3)-[LIVMFAC]-x-[GSALV]-[GSANHD]-C-x-[IVTACS]-[PLA]- [LIVMF]-[GSA]. |
Numerical results [info]
Total number of hits | 444 in 444 different sequences |
Number of true positive hits | 444 in 444 different sequences |
Number of 'unknown' hits | 0 |
Number of false positive hits | 0 |
Number of false negative sequences | 31 |
Number of 'partial' sequences | 2 |
Precision (true positives / (true positives + false positives)) | 100.00 % |
Recall (true positives / (true positives + false negatives)) | 93.47 % |
Comments [info]
Taxonomic range [info] | Archaea, Eukaryotes, Prokaryotes (Bacteria) |
Maximum number of repetitions [info] | 1 |
Site [info] | cofactor_binding at position 10 |
Version [info] | 1 |
Cross-references [info]
UniProtKB/Swiss-Prot True positive sequences |
444 sequences
HEM31_STRAW (Q82E76), HEM31_STRCO (Q9WX16), HEM32_STRAW (Q82P95), HEM32_STRCO (Q9KY00), HEM3_ACIAD (Q6FFA9), HEM3_ACIC1 (A0LRF1), HEM3_ACTSZ (A6VL87), HEM3_AERPE (Q9Y9J0), HEM3_AGRFC (Q8UC46), HEM3_ALCBS (Q0VM28), HEM3_ALIB4 (A8ERI4), HEM3_ALIF1 (Q5E8T5), HEM3_ALIFM (B5FF97), HEM3_ALISL (B6EPK1), HEM3_ALKEH (Q0A577), HEM3_ALKMQ (A6TJD5), HEM3_ALKOO (A8MGE4), HEM3_AQUAE (O66621), HEM3_ARATH (Q43316), HEM3_ARCFU (O29026), HEM3_BACAA (C3P9E9), HEM3_BACAC (C3L6Z5), HEM3_BACAH (A0RJ81), HEM3_BACAN (Q81LC7), HEM3_BACC0 (B7JQ57), HEM3_BACC1 (Q72ZW2), HEM3_BACC2 (B7IIX5), HEM3_BACC3 (C1ETR0), HEM3_BACC4 (B7HE96), HEM3_BACC7 (B7HQM4), HEM3_BACCN (A7GTE5), HEM3_BACCQ (B9IZ39), HEM3_BACCR (Q817R0), HEM3_BACCZ (Q633Y0), HEM3_BACHK (Q6HD62), HEM3_BACLD (Q65GK1), HEM3_BACMK (A9VIT8), HEM3_BACP2 (A8FFV2), HEM3_BACSU (P16616), HEM3_BACVZ (A7Z7A5), HEM3_BAUCH (Q1LU25), HEM3_BORBR (Q7WKM1), HEM3_BORPA (Q7W785), HEM3_BORPD (A9IKF3), HEM3_BORPE (Q7VVU9), HEM3_BOVIN (Q2KIN5), HEM3_BREBN (C0ZAH1), HEM3_BRUA1 (B2S842), HEM3_BRUA2 (Q2YLM5), HEM3_BRUA4 (A6WXJ2), HEM3_BRUAB (Q57B08), HEM3_BRUC2 (A9M8M2), HEM3_BRUMB (C0RFD1), HEM3_BRUME (Q8YJB0), HEM3_BRUO2 (A5VSL5), HEM3_BRUSI (B0CID9), HEM3_BRUSU (Q8FYI6), HEM3_BUCA5 (B8D8F3), HEM3_BUCAI (P57651), HEM3_BUCAT (B8D8B0), HEM3_BURCJ (B4E8C4), HEM3_BURCM (Q0BCU9), HEM3_BURM7 (A3MLK5), HEM3_BURM9 (A2SAH5), HEM3_BURMA (Q62LC0), HEM3_BURMS (A1V5U0), HEM3_BURO0 (B1JWR0), HEM3_BURP0 (A3NSN6), HEM3_BURP1 (Q3JUW3), HEM3_BURP6 (A3N700), HEM3_BURPS (Q63W73), HEM3_BURTA (Q2T071), HEM3_BURVG (A4JGV4), HEM3_CALMQ (A8MDU3), HEM3_CAMC1 (A7ZD37), HEM3_CAMC5 (A7GYU4), HEM3_CAMFF (A0RNT3), HEM3_CAMHC (A7I1S0), HEM3_CAMJ8 (A8FKW8), HEM3_CAMJD (A7H4J7), HEM3_CAMJE (Q9PHW9), HEM3_CAMJJ (A1VYQ4), HEM3_CAMJR (Q5HVM1), HEM3_CAMLR (B9KGA9), HEM3_CANAL (O94048), HEM3_CANGA (Q6FNR4), HEM3_CARHZ (Q3ACT3), HEM3_CAUSK (B0T287), HEM3_CAUVC (Q9ABZ8), HEM3_CAUVN (B8GXG1), HEM3_CHLCH (Q3AQF5), HEM3_CHLL2 (B3EIN1), HEM3_CHLL3 (Q3B2Z5), HEM3_CHLP8 (P28464), HEM3_CHLPB (B3EPK0), HEM3_CHLPD (A1BHD6), HEM3_CHLPM (A4SFJ8), HEM3_CHLT3 (B3QWI1), HEM3_CHLTE (Q8KCJ4), HEM3_CHRVO (Q7P207), HEM3_CITBB (B5EBG8), HEM3_CLOB8 (A6LSY5), HEM3_CLOBA (B2UXC4), HEM3_CLOBB (B2TPD7), HEM3_CLOD6 (Q180R9), HEM3_CLOK1 (B9DZL6), HEM3_CLONN (A0Q2B1), HEM3_CLOP1 (Q0TQG4), HEM3_CLOPE (Q8XKG4), HEM3_CLOPS (Q0ST16), HEM3_COLP3 (Q48AW8), HEM3_CORA7 (C3PKG2), HEM3_CORDI (Q6NJK0), HEM3_COREF (Q8FSF7), HEM3_CORGB (A4QB59), HEM3_CORGL (Q8NT90), HEM3_COXB1 (B6J6K0), HEM3_COXB2 (B6J3T6), HEM3_COXBN (A9KDC4), HEM3_COXBR (A9N910), HEM3_COXBU (Q83A37), HEM3_CROS8 (A7MQJ1), HEM3_CUTAK (Q6AB05), HEM3_DEBHA (Q6BM23), HEM3_DECAR (Q479S8), HEM3_DEIDV (C1CYD9), HEM3_DEIGD (Q1J288), HEM3_DEIRA (Q9RRY0), HEM3_DESAP (B1I4L8), HEM3_DESHD (B8G2M2), HEM3_DESHY (Q24VC8), HEM3_DESRM (A4J6H7), HEM3_DICDI (Q54P93), HEM3_DICNV (A5EW83), HEM3_ECO45 (B7MH66), HEM3_ECO55 (B7L959), HEM3_ECO57 (Q8XAP3), HEM3_ECO7I (B7NTE0), HEM3_ECO81 (B7N295), HEM3_ECO8A (B7M603), HEM3_ECOBW (C4ZZ69), HEM3_ECODH (B1XAH2), HEM3_ECOL6 (Q8FBP1), HEM3_ECOLI (P06983), HEM3_ECOLU (B7NFA7), HEM3_ECOSE (B6I4E0), HEM3_EHRCJ (Q3YSA8), HEM3_EHRCR (Q2GGC7), HEM3_ENT38 (A4WG12), HEM3_EREGS (Q75DY0), HEM3_ERWT9 (B2VG55), HEM3_ESCF3 (B7LU53), HEM3_EUGGR (P13446), HEM3_EXIS2 (B1YJV1), HEM3_EXISA (C4L4J6), HEM3_FRAP2 (B0TW04), HEM3_FRAT1 (Q14JI3), HEM3_FRATF (A7N9H6), HEM3_FRATH (Q2A5R3), HEM3_FRATM (B2SE34), HEM3_FRATN (A0Q481), HEM3_FRATO (Q0BP15), HEM3_FRATT (Q5NI31), HEM3_FRATW (A4IZY4), HEM3_FUSNN (Q8RFP5), HEM3_GEODF (B9M416), HEM3_GEOKA (Q5KWK6), HEM3_GEOMG (Q39QM7), HEM3_GEOSL (Q747I1), HEM3_GEOSM (C6DYY8), HEM3_GEOSW (C5D5K7), HEM3_GEOTN (A4IRG5), HEM3_GEOUR (A5GCW2), HEM3_GLOVI (Q7NGF7), HEM3_HAHCH (Q2SQ70), HEM3_HALH5 (Q9K8G0), HEM3_HALHL (A1WVT9), HEM3_HALSA (Q9HMY5), HEM3_HAMD5 (C4K4E3), HEM3_HELAH (Q17W61), HEM3_HELHP (Q7VFE9), HEM3_HELP2 (B6JKG8), HEM3_HELPG (B5ZA04), HEM3_HELPH (Q1CUR5), HEM3_HELPJ (Q9ZMJ7), HEM3_HELPS (B2US69), HEM3_HELPY (P56140), HEM3_HISS1 (Q0I178), HEM3_HISS2 (B0UWZ8), HEM3_HUMAN (P08397), HEM3_HYDCU (Q31JG5), HEM3_HYPBU (A2BL26), HEM3_HYPNA (Q0BX92), HEM3_IDILO (Q5QUS3), HEM3_IGNH4 (A8AAB4), HEM3_KLEP3 (B5XYL1), HEM3_KLEP7 (A6TGI8), HEM3_KLULA (Q6CT60), HEM3_KORVE (Q1INI6), HEM3_LARHH (C1D679), HEM3_LAWIP (Q1MPL2), HEM3_LEGPA (Q5X1F2), HEM3_LEGPH (Q5ZRY6), HEM3_LEGPL (Q5WT65), HEM3_LEIXX (Q6AHF1), HEM3_LISIN (Q92BF8), HEM3_LISMC (C1KVK3), HEM3_LISMF (Q71ZB2), HEM3_LISMH (B8DHJ2), HEM3_LISMO (Q8Y6X5), HEM3_LISW6 (A0AJ05), HEM3_LYSSC (B1HVD6), HEM3_MACCJ (B9E743), HEM3_MANSM (Q65VX7), HEM3_MARN8 (A1TXW9), HEM3_MARSD (C6BYB7), HEM3_METAC (Q8TT56), HEM3_METAR (Q0W5T2), HEM3_METBF (Q46CH0), HEM3_METBU (Q12WM8), HEM3_METCA (Q602K3), HEM3_METFK (Q1GXA1), HEM3_METJA (Q57989), HEM3_METMA (Q8PW57), HEM3_METS5 (A4YD92), HEM3_METTH (O26960), HEM3_MICLC (C5CB88), HEM3_MOUSE (P22907), HEM3_MYCA1 (A0QLI0), HEM3_MYCA9 (B1MHI5), HEM3_MYCBO (P64337), HEM3_MYCBP (A1KFY6), HEM3_MYCBT (C1AKJ0), HEM3_MYCGI (A4T340), HEM3_MYCLE (Q49808), HEM3_MYCMM (B2HRJ2), HEM3_MYCPA (Q73SS0), HEM3_MYCTA (A5TZP0), HEM3_MYCTO (P9WMP2), HEM3_MYCTU (P9WMP3), HEM3_MYCUA (A0PW29), HEM3_MYCVP (A1T3D3), HEM3_MYXXD (Q1D8Z8), HEM3_NATTJ (B2A1G7), HEM3_NEIMA (Q9JVS4), HEM3_NEIMB (Q9K0P6), HEM3_NEUCR (Q6MW51), HEM3_NITEU (Q82WS2), HEM3_NITHX (Q1QQP5), HEM3_NITSB (A6Q3S1), HEM3_NITV2 (Q72AV0), HEM3_NITV4 (A1VCX6), HEM3_NITV9 (B8DKW2), HEM3_NITWN (Q3SVF3), HEM3_NOCFA (Q5YP70), HEM3_NOSS1 (Q8YVU6), HEM3_OCEIH (Q8CXC0), HEM3_OLEA2 (Q30Y29), HEM3_ORYSJ (Q6H6D2), HEM3_PAEMA (O69110), HEM3_PARDP (A1B853), HEM3_PARMW (Q7U5C2), HEM3_PARP8 (B2JEN9), HEM3_PARPJ (B2T1D1), HEM3_PASMU (Q9CK24), HEM3_PEA(Q43082), HEM3_PECAS (Q6CZG3), HEM3_PECCP (C6DHC2), HEM3_PELPB (B4SFI2), HEM3_PELPD (A1AUE7), HEM3_PELTS (A5D3L5), HEM3_PHEZH (B4RC21), HEM3_PHOLL (Q7MYN1), HEM3_PROA2 (B4S922), HEM3_PROM0 (A3PBM0), HEM3_PROM1 (A2C0V4), HEM3_PROM2 (A8G3L1), HEM3_PROM3 (A2C7L8), HEM3_PROM4 (A9BEB6), HEM3_PROM5 (A2BVF7), HEM3_PROM9 (Q31C38), HEM3_PROMA (Q7VD89), HEM3_PROMH (B4F1X3), HEM3_PROMI (Q59684), HEM3_PROMM (Q7V697), HEM3_PROMP (Q7V2I1), HEM3_PROMS (A2BPX7), HEM3_PROMT (Q46GS7), HEM3_PSEA6 (Q15Z15), HEM3_PSEA7 (A6VE37), HEM3_PSEA8 (B7V5F0), HEM3_PSEAB (Q02EA3), HEM3_PSEAE (Q60169), HEM3_PSEE4 (Q1I316), HEM3_PSEF5 (Q4K3X3), HEM3_PSEFS (C3K424), HEM3_PSEP1 (A5VWX3), HEM3_PSEPF (Q3K4T0), HEM3_PSEPG (B0KH05), HEM3_PSEPK (Q88RE5), HEM3_PSEPW (B1J1V2), HEM3_PSESM (Q88B91), HEM3_PSEU2 (Q500N6), HEM3_PSYIN (A1T0R0), HEM3_PYRAE (Q8ZYW7), HEM3_PYRAR (A4WN24), HEM3_PYRCJ (A3MWV7), HEM3_PYRIL (A1RQK2), HEM3_PYRNV (B1YDP0), HEM3_RALN1 (Q8XWW3), HEM3_RAT(P19356), HEM3_RHILO (Q98EI7), HEM3_RHIME (Q92LH7), HEM3_RHOBA (Q7UPN0), HEM3_RICAE (C3PNS9), HEM3_RICAH (A8GNR5), HEM3_RICB8 (A8GXC8), HEM3_RICBR (Q1RJN7), HEM3_RICCK (A8EYJ9), HEM3_RICCN (Q92HR5), HEM3_RICFE (Q4ULA5), HEM3_RICM5 (A8F1Y8), HEM3_RICPR (Q9ZD77), HEM3_RICPU (C4K265), HEM3_RICRO (B0BY00), HEM3_RICRS (A8GSI6), HEM3_RICTY (Q68WR3), HEM3_ROSCS (A7NKU8), HEM3_ROSS1 (A5UU37), HEM3_RUBXD (Q1AUK3), HEM3_RUMCH (B8I0Q8), HEM3_RUMJO (Q59293), HEM3_RUTMC (A1AX51), HEM3_SACS2 (Q980U4), HEM3_SALAR (A9MJ10), HEM3_SALDC (B5FN93), HEM3_SALPA (Q5PKL7), HEM3_SALPC (C0Q3B3), HEM3_SALPK (B5BIU8), HEM3_SALSV (B4TNV3), HEM3_SALTI (P0A1Q9), HEM3_SALTY (P0A1Q8), HEM3_SCHPO (Q09899), HEM3_SERP5 (A8G848), HEM3_SHEB2 (B8E879), HEM3_SHEB5 (A3D9Q4), HEM3_SHEB8 (A6WTG0), HEM3_SHEB9 (A9L5G0), HEM3_SHEFN (Q088L3), HEM3_SHEHH (B0TJ54), HEM3_SHEON (Q8E9H0), HEM3_SHEPA (A8GZG4), HEM3_SHEPC (A4YBG2), HEM3_SHESA (A0KS60), HEM3_SHESH (A8G0W4), HEM3_SHESM (Q0HN99), HEM3_SHESR (Q0HQI7), HEM3_SHESW (A1RPD7), HEM3_SHEWM (B1KQC6), HEM3_SHIFL (Q83PH4), HEM3_SHOC1 (Q5WEP5), HEM3_SORC5 (A9FDP9), HEM3_SPHAL (Q1GP41), HEM3_STAA1 (A7X391), HEM3_STAA2 (A6U2D8), HEM3_STAA3 (Q2FG66), HEM3_STAA8 (O34090), HEM3_STAA9 (A5ITJ5), HEM3_STAAB (Q2YTB9), HEM3_STAAC (Q5HFA2), HEM3_STAAE (A6QHK4), HEM3_STAAM (P64340), HEM3_STAAN (P64341), HEM3_STAAR (Q6GG35), HEM3_STAAS (Q6G8Q5), HEM3_STAAT (A8Z2J1), HEM3_STAAW (Q8NW74), HEM3_STACT (B9DNE1), HEM3_STAEQ (Q5HNN3), HEM3_STAES (Q8CNY8), HEM3_STAHJ (Q4L709), HEM3_STAS1 (Q49YA2), HEM3_STRM5 (B4SJT8), HEM3_STRMK (B2FI06), HEM3_SULDN (Q30S90), HEM3_SULIA (C3MZR8), HEM3_SULIK (C4KIZ9), HEM3_SULIL (C3MJ21), HEM3_SULIM (C3MYD9), HEM3_SULIN (C3NF70), HEM3_SULIY (C3N841), HEM3_SULNB (A6Q7Y4), HEM3_SULTO (Q976H1), HEM3_SYNC1 (Q3A009), HEM3_SYNE7 (Q31PM2), HEM3_SYNFM (A0LN73), HEM3_SYNR3 (A5GSE0), HEM3_SYNS3 (Q0I8I3), HEM3_SYNS9 (Q3AWQ4), HEM3_SYNSC (Q3ALS9), HEM3_SYNWW (Q0AZ43), HEM3_SYNY3 (P73660), HEM3_THEAC (Q9HKM5), HEM3_THEFY (Q47LA7), HEM3_THET2 (Q72H57), HEM3_THET8 (Q5SLE8), HEM3_THEVB (Q8DIE4), HEM3_THEVO (Q97B26), HEM3_THIDA (Q3SFT5), HEM3_THISH (B8GSU8), HEM3_TRIL1 (B3E2H7), HEM3_VESOH (A5CW34), HEM3_VIBA3 (B7VMD9), HEM3_VIBC1 (A7MXU9), HEM3_VIBCH (Q9KVM1), HEM3_VIBPA (Q87KI9), HEM3_VIBVU (Q8DD85), HEM3_VIBVY (Q7MQC7), HEM3_WOLSU (Q7M8L2), HEM3_WOLWR (C0R2M3), HEM3_XANAC (Q8PPR3), HEM3_XANC8 (Q4UYZ4), HEM3_XANCB (B0RNI9), HEM3_XANCP (Q8P536), HEM3_XANE5 (Q3BXV3), HEM3_XANOM (Q2NYU4), HEM3_XANOP (B2SMV3), HEM3_XANOR (Q5GVL2), HEM3_XYLF2 (B2I5K8), HEM3_XYLFA (Q9PCX7), HEM3_XYLFM (B0U2W8), HEM3_XYLFT (Q87CC9), HEM3_YARLI (Q6C097), HEM3_YEAST (P28789), HEM3_YERE8 (A1JI86), HEM3_YERP3 (A7FD67), HEM3_YERPA (Q1CBN1), HEM3_YERPB (B2K065), HEM3_YERPE (P46355), HEM3_YERPG (A9R8K0), HEM3_YERPN (Q1CNI3), HEM3_YERPP (A4TRA8), HEM3_YERPS (Q66G00), HEM3_YERPY (B1JPE6)» more
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UniProtKB/Swiss-Prot False negative sequences |
31 sequences
HEM3_ACET2 (A3DIF0), HEM3_ACIF2 (B7JBH8), HEM3_ACIF5 (B5ERN6), HEM3_ALBFT (Q21XQ9), HEM3_BLOFL (Q7VRM4), HEM3_BLOPB (Q491Z6), HEM3_CALS8 (A4XK06), HEM3_CHLMU (Q9PK95), HEM3_CHLPN (Q9Z9C9), HEM3_CHLTR (O84301), HEM3_CLOAB (Q97MU4), HEM3_CLOB1 (A7FSG8), HEM3_CLOB6 (C3L2Z3), HEM3_CLOBH (A5I0B2), HEM3_CLOBJ (C1FVB9), HEM3_CLOBK (B1IHD1), HEM3_CLOBL (A7GBW3), HEM3_CLOBM (B1KY15), HEM3_CYTH3 (Q11XT5), HEM3_DESOH (A8ZWG5), HEM3_LACE2 (C4Z552), HEM3_LIMRD (A5VM67), HEM3_LIMRJ (B2G9H4), HEM3_METKA (Q8TXC8), HEM3_MOOTA (Q2RJ26), HEM3_NITMS (A9A1A1), HEM3_ORITB (A5CDH4), HEM3_ORITI (B3CUP9), HEM3_PICTO (Q6L2G8), HEM3_STRSV (A3CL78), HEM3_SYNAS (Q2LQU2)» more |
UniProtKB/Swiss-Prot 'Partial' sequences |
2 sequences
HEM3_DICCH (P40129), HEM3_YERIN (P30527) |
PDB [Detailed view] |
18 PDB
1AH5; 1GTK; 1PDA; 1YPN; 2YPN; 3ECR; 3EQ1; 4HTG; 5H6O; 5M6R; 5M7F; 7AAJ; 7AAK; 7CCX; 7CCY; 7CCZ; 7CD0; 8PND » more |