PROSITE logo

PROSITE entry PS00536


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00536
Entry name [info] UBIQUITIN_ACTIVAT_1
Accession [info] PS00536
Entry type [info] PATTERN
Date [info] 01-DEC-1991 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00463

Name and characterization of the entry

Description [info] Ubiquitin-activating enzyme signature 1.
Pattern [info] 
K-[AI]-[CL]-S-G-K-[FI]-x-[PQ].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 15 in 15 different sequences
Number of true positive hits 15 in 15 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 14
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 51.72 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 15 sequences 

SAE2_HUMAN  (Q9UBT2), SAE2_MOUSE  (Q9Z1F9), UBA1Y_MOUSE (P31254), 

UBA1_BOVIN  (A3KMV5), UBA1_DICDI  (Q55C16), UBA1_HUMAN  (P22314), 
UBA1_MOUSE  (Q02053), UBA1_RABIT  (Q29504), UBA1_RAT(Q5U300), 
UBA1_YEAST  (P22515), UBE11_ARATH (P93028), UBE11_WHEAT (P20973), 
UBE12_ARATH (P92974), UBE12_WHEAT (P31251), UBE13_WHEAT (P31252)
» more

UniProtKB/Swiss-Prot
False negative sequences		 14 sequences 

SAE2A_XENLA (Q642Q1), SAE2B_XENLA (Q7ZY60), SAE2_DANRE  (Q7SXG4), 

SAE2_XENTR  (Q28GH3), UBA1_SCHPO  (O94609), UBA3_DICDI  (Q54QG9), 
UBA3_HUMAN  (Q8TBC4), UBA3_MOUSE  (Q8C878), UBA3_RAT(Q99MI7), 
UBA3_SCHPO  (Q09765), UBA3_YEAST  (Q99344), UBA6_HUMAN  (A0AVT1), 
UBA6_MOUSE  (Q8C7R4), UBA7_HUMAN  (P41226)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 2 sequences 

UBA1_CANAW  (P52495), UBE1Y_OSPRU (P31255)


				
	

	

		PDB
[Detailed view]		
		
			24 PDB
			


			1Y8Q; 1Y8R; 3CMM; 3KYC; 3KYD; 4NNJ; 4P22; 5L6H; 5L6I; 5L6J; 5TR4; 6CWY; 
			
				6CWZ; 6DC6; 6NYA; 6XOG; 6XOH; 6XOI; 6ZHS; 6ZHT; 6ZHU; 6ZQH; 7K5J; 7ZH9
			
			

			» more