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PROSITE entry PS00536


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PURL: https://purl.expasy.org/prosite/signature/PS00536

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General information about the entry

Entry name [info] UBIQUITIN_ACTIVAT_1
Accession [info] PS00536
Entry type [info] PATTERN
Date [info] 01-DEC-1991 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00463

Name and characterization of the entry

Description [info] Ubiquitin-activating enzyme signature 1.
Pattern [info] 
K-[AI]-[CL]-S-G-K-[FI]-x-[PQ].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 15 in 15 different sequences
Number of true positive hits 15 in 15 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 14
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 51.72 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 15 sequences 

SAE2_HUMAN  (Q9UBT2), SAE2_MOUSE  (Q9Z1F9), UBA1Y_MOUSE (P31254), 

UBA1_BOVIN  (A3KMV5), UBA1_DICDI  (Q55C16), UBA1_HUMAN  (P22314), 
UBA1_MOUSE  (Q02053), UBA1_RABIT  (Q29504), UBA1_RAT(Q5U300), 
UBA1_YEAST  (P22515), UBE11_ARATH (P93028), UBE11_WHEAT (P20973), 
UBE12_ARATH (P92974), UBE12_WHEAT (P31251), UBE13_WHEAT (P31252)
» more

UniProtKB/Swiss-Prot
False negative sequences		 14 sequences 

SAE2A_XENLA (Q642Q1), SAE2B_XENLA (Q7ZY60), SAE2_DANRE  (Q7SXG4), 

SAE2_XENTR  (Q28GH3), UBA1_SCHPO  (O94609), UBA3_DICDI  (Q54QG9), 
UBA3_HUMAN  (Q8TBC4), UBA3_MOUSE  (Q8C878), UBA3_RAT(Q99MI7), 
UBA3_SCHPO  (Q09765), UBA3_YEAST  (Q99344), UBA6_HUMAN  (A0AVT1), 
UBA6_MOUSE  (Q8C7R4), UBA7_HUMAN  (P41226)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 2 sequences 

UBA1_CANAW  (P52495), UBE1Y_OSPRU (P31255)


				
	

	

		PDB
[Detailed view]		
		
			24 PDB
			


			pdb_00001y8q; pdb_00001y8r; pdb_00003cmm; pdb_00003kyc; pdb_00003kyd; pdb_00004nnj; pdb_00004p22; pdb_00005l6h; pdb_00005l6i; pdb_00005l6j; pdb_00005tr4; pdb_00006cwy; 
			
				pdb_00006cwz; pdb_00006dc6; pdb_00006nya; pdb_00006xog; pdb_00006xoh; pdb_00006xoi; pdb_00006zhs; pdb_00006zht; pdb_00006zhu; pdb_00006zqh; pdb_00007k5j; pdb_00007zh9
			
			

			» more