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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS00537


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PURL: https://purl.expasy.org/prosite/signature/PS00537

Direct ScanProsite submission
General information about the entry

Entry name [info] CYTOCHROME_B559
Accession [info] PS00537
Entry type [info] PATTERN
Date [info] 01-DEC-1991 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00464

Name and characterization of the entry

Description [info] Cytochrome b559 subunits heme-binding site signature.
Pattern [info] 
[LIV]-x-[ST]-[LIVF]-R-[FYW]-x(2)-[IVL]-H-[STGAV]-[LIV]-[STGA]-[IV]-P.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 300 in 300 different sequences
Number of true positive hits 300 in 300 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 19
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 94.04 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] heme at position 9
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 300 sequences 

PSBE_ACAM1  (B0C6T2), PSBE_ACOCL  (Q3V518), PSBE_ADICA  (Q85FK5), 

PSBE_AGRST  (A1EA25), PSBE_AMBTC  (Q70XY9), PSBE_ANTAG  (Q85C42), 
PSBE_ARATH  (P56779), PSBE_ATRBE  (P59702), PSBE_BETVU  (P69382), 
PSBE_BIGNA  (Q06J11), PSBE_CALFG  (Q7YJV8), PSBE_CHAGL  (Q8M9W8), 
PSBE_CHAVU  (Q1ACI7), PSBE_CHLRE  (P48268), PSBE_CHLVU  (P56309), 
PSBE_CITSI  (Q09MG1), PSBE_COFAR  (A0A352), PSBE_CROS5  (B1WVS0), 
PSBE_CUCSA  (Q4VZH5), PSBE_CUSGR  (Q8MAV7), PSBE_CUSRE  (A7M969), 
PSBE_CYACA  (Q9TM20), PSBE_CYAM1  (Q85FQ2), PSBE_CYAP4  (B8HVD7), 
PSBE_CYAPA  (P19152), PSBE_DAUCA  (Q0G9U5), PSBE_DRIGR  (Q06GY0), 
PSBE_EMIHU  (Q4G380), PSBE_EUCGG  (Q49KY2), PSBE_EUGGR  (P05333), 
PSBE_GINBI  (Q9THZ3), PSBE_GLOC7  (B7KH62), PSBE_GOSBA  (A0ZZ52), 
PSBE_GOSHI  (Q2L925), PSBE_GRATL  (Q6B8K4), PSBE_GUITH  (O78466), 
PSBE_HELAN  (Q1KXU2), PSBE_HORVU  (P69390), PSBE_HUPLU  (Q5SD43), 
PSBE_JASNU  (Q06RB5), PSBE_LACSA  (Q332W1), PSBE_LIRTU  (Q0G9K2), 
PSBE_LOTJA  (Q9BBR5), PSBE_MAIZE  (P69388), PSBE_MARPO  (P06851), 
PSBE_MESCR  (P36442), PSBE_MESVI  (Q9MUQ0), PSBE_MICAN  (B0JLV1), 
PSBE_MORIN  (Q09X00), PSBE_NEPOL  (Q9TKY1), PSBE_NICSY  (Q3C1L3), 
PSBE_NICTO  (Q76IC3), PSBE_NOSP7  (B2J6T0), PSBE_NOSS1  (Q8YQI2), 
PSBE_NYMAL  (Q6EW36), PSBE_OENBE  (P05170), PSBE_OENEH  (Q9MTK5), 
PSBE_OLTVI  (Q20EW2), PSBE_ORYNI  (Q6ENF6), PSBE_ORYSA  (P0C368), 
PSBE_ORYSI  (P0C369), PSBE_ORYSJ  (P0C370), PSBE_OSTTA  (Q0P3N6), 
PSBE_PANGI  (Q68RY9), PSBE_PEA(P13554), PSBE_PELHO  (Q06FK9), 
PSBE_PHAAO  (Q3BAM3), PSBE_PHATC  (A0T0A3), PSBE_PHYPA  (Q6YXL9), 
PSBE_PICP2  (Q8RSW3), PSBE_PINKO  (P59703), PSBE_PINTH  (P41615), 
PSBE_PIPCE  (Q06GP3), PSBE_POPAL  (Q14FE0), PSBE_POPDE  (P69385), 
PSBE_PORPU  (P51391), PSBE_PSINU  (Q8WI04), PSBE_PYRYE  (Q1XD96), 
PSBE_RIPO1  (B7K626), PSBE_SACHY  (Q6L383), PSBE_SACOF  (Q6ENU7), 
PSBE_SECCE  (P69387), PSBE_SOLBU  (Q2MIH0), PSBE_SOLLC  (Q2MI83), 
PSBE_SOLTU  (Q2VEG1), PSBE_SORBI  (A1E9U1), PSBE_SOYBN  (Q2PMR7), 
PSBE_SPIOL  (P69383), PSBE_STAPU  (Q32RX7), PSBE_STIHE  (Q06SG1), 
PSBE_SYNE7  (Q8KPP3), PSBE_SYNJA  (Q2JS34), PSBE_SYNJB  (Q2JLF0), 
PSBE_SYNP6  (Q5N556), PSBE_SYNY3  (P09190), PSBE_TETOB  (Q1KVR5), 
PSBE_THAPS  (A0T0U2), PSBE_THEVB  (Q8DIP0), PSBE_THEVL  (P12238), 
PSBE_TOBAC  (P69384), PSBE_TRICV  (P49473), PSBE_TRIEI  (Q10YT0), 
PSBE_TRIV2  (Q3MC09), PSBE_TUPAK  (Q3ZJ22), PSBE_VITVI  (Q0ZJ03), 
PSBE_WHEAT  (P69386), PSBE_ZYGCR  (Q32RJ5), PSBF_ACOCL  (Q7J1C5), 
PSBF_ADICA  (Q85FK6), PSBF_AGARO  (Q6EYW3), PSBF_AGRST  (A1EA24), 
PSBF_ALLTE  (Q67HC1), PSBF_AMBTC  (P60248), PSBF_ANACO  (Q67HN7), 
PSBF_ANTAG  (P60249), PSBF_ARATH  (P62095), PSBF_ARIMA  (Q6EYV9), 
PSBF_ASACA  (Q7J1C2), PSBF_ASPOF  (Q67HB3), PSBF_ATRBE  (P60250), 
PSBF_BETVU  (P46613), PSBF_BIGNA  (Q06J12), PSBF_BOWSE  (Q71L83), 
PSBF_BUTUM  (Q67HR9), PSBF_CABCA  (Q7J1C1), PSBF_CALFG  (Q7HKX7), 
PSBF_CALFL  (Q7J1B9), PSBF_CALSE  (Q7H8E7), PSBF_CANWI  (Q6EYV1), 
PSBF_CEDDE  (Q71L79), PSBF_CERDE  (Q7J1B8), PSBF_CERJA  (Q7J1B7), 
PSBF_CHAGL  (P60251), PSBF_CHAVU  (Q1ACI8), PSBF_CHLMO  (P46305), 
PSBF_CHLRE  (Q08363), PSBF_CHLVU  (P56310), PSBF_CITSI  (Q09MG2), 
PSBF_COECR  (Q67HH3), PSBF_COFAR  (A0A351), PSBF_CONAR  (Q7H8E5), 
PSBF_CORMA  (Q6EYU4), PSBF_CRETR  (Q7H8A5), PSBF_CROS5  (B1WVR8), 
PSBF_CUCSA  (Q4VZH6), PSBF_CUNLA  (Q6EYU0), PSBF_CUSEU  (Q8MAW5), 
PSBF_CUSGR  (Q7H823), PSBF_CUSJA  (Q7H834), PSBF_CUSPE  (Q7H825), 
PSBF_CYACA  (Q9TM21), PSBF_CYAM1  (Q85FQ3), PSBF_CYAP4  (B8HVD8), 
PSBF_CYAPA  (P19153), PSBF_CYCRE  (Q71L71), PSBF_DAUCA  (Q0G9U6), 
PSBF_DIOBU  (Q7J1B5), PSBF_DRIGR  (Q06GY1), PSBF_DRIWI  (Q7J1B3), 
PSBF_EMIHU  (Q4G381), PSBF_ENSVE  (Q67HM5), PSBF_EPHSI  (Q8HRZ6), 
PSBF_EUCGG  (Q49KY3), PSBF_EUGGR  (P05334), PSBF_EUOAL  (Q6EYT6), 
PSBF_GINBI  (Q7J1B1), PSBF_GLOC7  (B7KH61), PSBF_GLOVI  (Q7NMA9), 
PSBF_GNEGN  (Q9GFC3), PSBF_GOSBA  (A0ZZ51), PSBF_GOSHI  (Q2L918), 
PSBF_GRATL  (Q6B8K5), PSBF_GUITH  (O78465), PSBF_GUNCH  (Q7HIV1), 
PSBF_HELAN  (Q1KXU3), PSBF_HORVU  (P60126), PSBF_HOUCO  (Q6EYS6), 
PSBF_HUPLU  (Q5SD42), PSBF_HYDCA  (Q7HIV0), PSBF_HYDMC  (Q6EYS3), 
PSBF_ILLPA  (Q7J1A9), PSBF_IPOAL  (Q7H8J8), PSBF_IPOAQ  (Q7H8K9), 
PSBF_IPOBA  (Q7H8K0), PSBF_IPOCC  (Q7H8L6), PSBF_IPOOB  (Q7H8I8), 
PSBF_IPOQU  (Q7H8L3), PSBF_IPOSE  (Q7H8K7), PSBF_IPOWR  (Q7H8L1), 
PSBF_JASNU  (Q06RB6), PSBF_LACFR  (Q7J1A7), PSBF_LACSA  (Q332W2), 
PSBF_LILSU  (Q7HIU8), PSBF_LIRTU  (Q7J1A5), PSBF_LOTJA  (Q9BBR6), 
PSBF_MAGST  (Q7HIU6), PSBF_MAIRA  (Q67HA1), PSBF_MAIZE  (P69523), 
PSBF_MARPO  (P06853), PSBF_MESCR  (P69524), PSBF_MESVI  (Q9MUQ1), 
PSBF_METGY  (Q71L59), PSBF_MICAN  (B0JLV0), PSBF_MONCA  (Q7H828), 
PSBF_MORIN  (Q09X01), PSBF_MUIMA  (Q67H97), PSBF_MUSCM  (Q67H93), 
PSBF_NAREL  (Q67H89), PSBF_NELLU  (Q6EYS0), PSBF_NEPOL  (Q9TKY2), 
PSBF_NICGU  (Q2UVD8), PSBF_NICSY  (Q7HML6), PSBF_NICTO  (Q7HML5), 
PSBF_NOSP7  (B2J6T1), PSBF_NOSS1  (Q8YQI1), PSBF_NYMAL  (Q6EW37), 
PSBF_NYMOD  (Q7IW40), PSBF_OENBE  (P62097), PSBF_OENEH  (P62098), 
PSBF_OLTVI  (Q20EW3), PSBF_ORYNI  (Q6ENF7), PSBF_ORYSA  (P0C399), 
PSBF_ORYSI  (P0C400), PSBF_ORYSJ  (P0C401), PSBF_OSTTA  (Q0P3N7), 
PSBF_PANGI  (Q68RZ0), PSBF_PARMW  (Q7U9Q0), PSBF_PEA(P62096), 
PSBF_PELHO  (Q06FL0), PSBF_PHAAO  (Q3BAM4), PSBF_PHATC  (A0T0A4), 
PSBF_PHOTN  (Q67HD7), PSBF_PHYAM  (Q6EYR0), PSBF_PHYPA  (Q6YXL8), 
PSBF_PICP2  (Q8RSW2), PSBF_PINKO  (Q85X32), PSBF_PINTH  (P41616), 
PSBF_PIPCE  (Q06GP4), PSBF_POPAL  (Q14FE1), PSBF_POPDE  (P62099), 
PSBF_PORPU  (P51390), PSBF_PROM0  (A3PB20), PSBF_PROM2  (A8G2V9), 
PSBF_PROM3  (A2CCQ1), PSBF_PROM4  (A9BDU5), PSBF_PROM5  (A2BUS9), 
PSBF_PROM9  (Q31CN4), PSBF_PROMA  (Q7VDN9), PSBF_PROMM  (Q7V4Q1), 
PSBF_PROMP  (Q7V2Z9), PSBF_PROMS  (A2BP98), PSBF_PSINU  (Q8WI05), 
PSBF_PYRYE  (Q1XD97), PSBF_RIPO1  (B7K625), PSBF_SACHY  (Q6L384), 
PSBF_SACOF  (Q6ENU8), PSBF_SAGLA  (Q7HIU1), PSBF_SARHE  (Q6EYP8), 
PSBF_SAUCE  (Q7J1A3), PSBF_SCHCH  (Q7HIT9), PSBF_SCIVE  (Q7HIT7), 
PSBF_SECCE  (P60127), PSBF_SISMO  (Q67HD3), PSBF_SOLBU  (Q2MIH1), 
PSBF_SOLLC  (Q3SC83), PSBF_SOLTU  (Q2VEG2), PSBF_SORBI  (A1E9U0), 
PSBF_SOYBN  (Q2PMR8), PSBF_SPAWA  (Q7HIT5), PSBF_SPIOL  (P60128), 
PSBF_STAER  (Q71L52), PSBF_STAPU  (Q32RX6), PSBF_STEPS  (Q6EYP2), 
PSBF_STIHE  (Q06SC5), PSBF_SYNE7  (Q8KPP2), PSBF_SYNJA  (Q2JS35), 
PSBF_SYNJB  (Q2JLE9), PSBF_SYNP6  (Q5N555), PSBF_SYNS9  (Q3B0C7), 
PSBF_SYNSC  (Q3AN57), PSBF_SYNY3  (P09191), PSBF_TAXBR  (Q6EYN1), 
PSBF_TETOB  (Q1KVX3), PSBF_THAPS  (A0T0U1), PSBF_THEVB  (Q8DIN9), 
PSBF_THEVL  (P12239), PSBF_THUPL  (Q6EYM7), PSBF_TOBAC  (P60124), 
PSBF_TRICV  (P49474), PSBF_TRIEI  (Q10YS9), PSBF_TRIV2  (Q3MC10), 
PSBF_TROAR  (Q7J1A2), PSBF_TUPAK  (Q3ZJ21), PSBF_TYPAN  (Q67HJ7), 
PSBF_VITVI  (Q0ZJ04), PSBF_WELMI  (Q6YLT4), PSBF_WHEAT  (P60125), 
PSBF_YUCGL  (Q67H85), PSBF_ZAMFU  (Q7IW43), PSBF_ZYGCR  (Q32RJ6)
» more

UniProtKB/Swiss-Prot
False negative sequences		 19 sequences 

PSBE_GLOVI  (Q7NMB0), PSBE_PARMW  (Q7U9P9), PSBE_PROM0  (A3PB19), 

PSBE_PROM1  (A2C0D1), PSBE_PROM2  (A8G2V8), PSBE_PROM3  (A2CCQ0), 
PSBE_PROM4  (A9BDU4), PSBE_PROM5  (A2BUS8), PSBE_PROM9  (Q31CN5), 
PSBE_PROMA  (Q7VDP0), PSBE_PROMM  (Q7V4Q2), PSBE_PROMP  (Q7V300), 
PSBE_PROMS  (A2BP97), PSBE_PROMT  (Q46H81), PSBE_SYNPW  (A5GIB0), 
PSBE_SYNR3  (A5GQF4), PSBE_SYNS3  (Q0IDJ7), PSBE_SYNS9  (Q3B0C6), 
PSBE_SYNSC  (Q3AN56)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

PSBF_CAPAN  (Q03367)


				
	

	

		PDB
[Detailed view]		
		
			134 PDB
			


			pdb_00001izl; pdb_00001s5l; pdb_00001w5c; pdb_00002axt; pdb_00003a0b; pdb_00003a0h; pdb_00003jcu; pdb_00003kzi; pdb_00003wu2; pdb_00004fby; pdb_00004il6; pdb_00004ixq; 
			
				pdb_00004ixr; pdb_00004pbu; pdb_00004pj0; pdb_00004rvy; pdb_00004tnh; pdb_00004tni; pdb_00004tnj; pdb_00004tnk; pdb_00004ub6; pdb_00004ub8; pdb_00004v62; pdb_00004v82; 
				pdb_00004yuu; pdb_00005b5e; pdb_00005b66; pdb_00005e79; pdb_00005e7c; pdb_00005gth; pdb_00005gti; pdb_00005h2f; pdb_00005kaf; pdb_00005kai; pdb_00005mdx; pdb_00005mx2; 
				pdb_00005tis; pdb_00005v2c; pdb_00005ws5; pdb_00005ws6; pdb_00005xnl; pdb_00005xnm; pdb_00005zzn; pdb_00006dhe; pdb_00006dhf; pdb_00006dhg; pdb_00006dhh; pdb_00006dho; 
				pdb_00006dhp; pdb_00006jlj; pdb_00006jlk; pdb_00006jll; pdb_00006jlm; pdb_00006jln; pdb_00006jlo; pdb_00006jlp; pdb_00006kac; pdb_00006kad; pdb_00006kaf; pdb_00006w1o; 
				pdb_00006w1p; pdb_00006w1q; pdb_00006w1r; pdb_00006w1t; pdb_00006w1u; pdb_00006w1v; pdb_00006wj6; pdb_00006yp7; pdb_00007cji; pdb_00007cjj; pdb_00007cou; pdb_00007czl; 
				pdb_00007d1t; pdb_00007d1u; pdb_00007dxa; pdb_00007dxh; pdb_00007eda; pdb_00007n8o; pdb_00007nho; pdb_00007nhp; pdb_00007nhq; pdb_00007oui; pdb_00007rcv; pdb_00007rf1; 
				pdb_00007rf2; pdb_00007rf3; pdb_00007rf4; pdb_00007rf5; pdb_00007rf6; pdb_00007rf7; pdb_00007rf8; pdb_00007ymi; pdb_00007ymm; pdb_00007yq2; pdb_00007yq7; pdb_00008am5; 
				pdb_00008asl; pdb_00008bd3; pdb_00008ez5; pdb_00008f4c; pdb_00008f4d; pdb_00008f4e; pdb_00008f4f; pdb_00008f4g; pdb_00008f4h; pdb_00008f4i; pdb_00008f4j; pdb_00008f4k; 
				pdb_00008gn0; pdb_00008gn1; pdb_00008gn2; pdb_00008ir5; pdb_00008ir6; pdb_00008ir7; pdb_00008ir8; pdb_00008ir9; pdb_00008ira; pdb_00008irb; pdb_00008irc; pdb_00008ird; 
				pdb_00008ire; pdb_00008irf; pdb_00008irg; pdb_00008irh; pdb_00008iri; pdb_00008iwh; pdb_00008j5k; pdb_00008kde; pdb_00008r2i; pdb_00008tow; pdb_00008z9d; pdb_00008zee; 
				pdb_00009eh5; pdb_00009evx
			
			

			» more