PROSITE logo
Black ribbon
We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS00547


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
PURL: https://purl.expasy.org/prosite/signature/PS00547

Direct ScanProsite submission
General information about the entry

Entry name [info] TRANSGLUTAMINASES
Accession [info] PS00547
Entry type [info] PATTERN
Date [info] 01-DEC-1991 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00473
Associated ProRule [info] PRU10024

Name and characterization of the entry

Description [info] Transglutaminases active site.
Pattern [info]
[GT]-Q-[CA]-W-V-x-[SA]-[GAS]-[IVT]-x(2)-T-x-[LMSC]-R-[CSAG]-[LV]-G.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 31 in 31 different sequences
Number of true positive hits 31 in 31 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] active_site at position 3
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
31 sequences

ANNU_SCHAM  (P52183), EPB42_BOVIN (O46510), EPB42_HUMAN (P16452), 
EPB42_MOUSE (P49222), F13A_HUMAN  (P00488), F13A_MOUSE  (Q8BH61), 
F13A_RAT(O08619), TGM1_CANLF  (Q9GLK0), TGM1_HUMAN  (P22735), 
TGM1_MOUSE  (Q9JLF6), TGM1_RABIT  (P22758), TGM1_RAT(P23606), 
TGM2_BOVIN  (P51176), TGM2_CAVCU  (P08587), TGM2_CHICK  (Q01841), 
TGM2_HUMAN  (P21980), TGM2_MOUSE  (P21981), TGM2_PAGMA  (P52181), 
TGM2_RAT(Q9WVJ6), TGM3L_HUMAN (O95932), TGM3_BOVIN  (A6QP57), 
TGM3_HUMAN  (Q08188), TGM3_MOUSE  (Q08189), TGM3_RAT(D4A5U3), 
TGM4_HUMAN  (P49221), TGM4_MOUSE  (Q8BZH1), TGM4_RAT(Q99041), 
TGM5_HUMAN  (O43548), TGM5_MOUSE  (Q9D7I9), TGM7_HUMAN  (Q96PF1), 
TGMH_TACTR  (Q05187)
» more

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

F13A_BOVIN  (P12260)

		
PDB
[Detailed view]
53 PDB

pdb_00001evu; pdb_00001ex0; pdb_00001f13; pdb_00001fie; pdb_00001g0d; pdb_00001ggt; pdb_00001ggu; pdb_00001ggy; pdb_00001kv3; pdb_00001l9m; pdb_00001l9n; pdb_00001nud; pdb_00001nuf; pdb_00001nug; pdb_00001qrk; pdb_00002q3z; pdb_00003ly6; pdb_00003s3j; pdb_00003s3p; pdb_00003s3s; pdb_00004kty; pdb_00004pyg; pdb_00005mhl; pdb_00005mhm; pdb_00005mhn; pdb_00005mho; pdb_00006a8p; pdb_00006kzb; pdb_00007tvz; pdb_00007tw0; pdb_00007tw1; pdb_00007tw3; pdb_00007tw5; pdb_00007tw6; pdb_00007uzs; pdb_00007v0k; pdb_00007v0q; pdb_00008cmt; pdb_00008cmu; pdb_00008cs9; pdb_00008csl; pdb_00008csw; pdb_00008cte; pdb_00008oxv; pdb_00008oxw; pdb_00008oxx; pdb_00008oxy; pdb_00008rmx; pdb_00008rmy; pdb_00008tr9; pdb_00009bc2; pdb_00009bc3; pdb_00009bc4
» more