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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS00551


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PURL: https://purl.expasy.org/prosite/signature/PS00551

Direct ScanProsite submission
General information about the entry

Entry name [info] MOLYBDOPTERIN_PROK_1
Accession [info] PS00551
Entry type [info] PATTERN
Date [info] 01-DEC-1991 CREATED;
01-NOV-1997 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00392

Name and characterization of the entry

Description [info] Prokaryotic molybdopterin oxidoreductases signature 1.
Pattern [info] 
[STAN]-x-[CH]-x(2,3)-C-[STAG]-[GSTVMF]-x-C-x-[LIVMFYW]-x-[LIVMA]-x(3,4)-
[DENQKHT].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 187 in 187 different sequences
Number of true positive hits 173 in 173 different sequences
Number of 'unknown' hits 0
Number of false positive hits 14 in 14 different sequences
Number of false negative sequences 41
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 92.51 %
Recall (true positives / (true positives + false negatives)) 80.84 %

Comments [info]

Taxonomic range [info] Archaea, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 173 sequences 

DMSA_ECOLI  (P18775), DMSA_HAEIN  (P45004), FDHA1_METMP (Q6LXQ1), 

FDHA2_METMP (F1SVN3), FDHA_MEGGA  (Q934F5), FDHA_METFO  (P06131), 
FDHA_METJA  (P61159), FDHA_MOOTH  (P77908), FDHF_ECOLI  (P07658), 
FDHL_STAA3  (Q2FEI5), FDHL_STAA8  (Q2FVV9), FDHL_STAAB  (Q2YYT1), 
FDHL_STAAC  (Q5HDP9), FDHL_STAAM  (Q931G2), FDHL_STAAN  (Q99RW4), 
FDHL_STAAR  (Q6GEC4), FDHL_STAAS  (Q6G711), FDHL_STAAW  (Q7A057), 
FDHL_STAHJ  (Q4L8G8), FDHL_STAS1  (Q49ZN0), FDNGA_NITV2 (Q727P3), 
FDNG_ECOLI  (P24183), FDOG_ECOLI  (P32176), FDXG_HAEIN  (P46448), 
NAPA1_PHOPR (Q6LTV9), NAPA2_PHOPR (Q6LQJ3), NAPA_ACTP2  (A3N277), 
NAPA_ACTP7  (B3H2D1), NAPA_ACTPJ  (B0BR28), NAPA_ACTSZ  (A6VQY7), 
NAPA_AERHH  (A0KIM1), NAPA_AERS4  (A4SPG7), NAPA_AGGAC  (Q8VL02), 
NAPA_AGRFC  (Q8U7P1), NAPA_ALIF1  (Q5E3J6), NAPA_ALIFM  (B5FGW1), 
NAPA_BORBR  (Q7WIQ1), NAPA_BORPA  (Q7W733), NAPA_BORPD  (A9I7M5), 
NAPA_BRADU  (Q89EN5), NAPA_BRASB  (A5ED21), NAPA_BRASO  (A4Z0A1), 
NAPA_CAMC1  (A7ZCK4), NAPA_CAMC5  (A7GZP5), NAPA_CAMFF  (A0RQ36), 
NAPA_CAMHC  (A7I3Y7), NAPA_CAMJ8  (A8FLJ3), NAPA_CAMJE  (Q9PPD9), 
NAPA_CAMJJ  (A1VZC8), NAPA_CAMJR  (Q5HV12), NAPA_CAMLR  (B9KCQ2), 
NAPA_CERS4  (Q53176), NAPA_CITK8  (A8AE11), NAPA_COLP3  (Q487G4), 
NAPA_CUPNH  (P39185), NAPA_CUPPJ  (Q46RX3), NAPA_CUPTR  (B3R8B4), 
NAPA_DECAR  (Q47A87), NAPA_DINSH  (A8LLY9), NAPA_ECO24  (A7ZP28), 
NAPA_ECO27  (B7UFL9), NAPA_ECO45  (B7MFB8), NAPA_ECO55  (B7LAM9), 
NAPA_ECO57  (Q8XE47), NAPA_ECO5E  (B5YWZ7), NAPA_ECO7I  (B7NN18), 
NAPA_ECO81  (B7MXN6), NAPA_ECO8A  (B7M5P6), NAPA_ECOBW  (C4ZU48), 
NAPA_ECODH  (B1X8A2), NAPA_ECOHS  (A8A268), NAPA_ECOK1  (A1AD59), 
NAPA_ECOL5  (Q0TFN6), NAPA_ECOL6  (Q8CVW4), NAPA_ECOLC  (B1IY66), 
NAPA_ECOLI  (P33937), NAPA_ECOLU  (B7N5G7), NAPA_ECOSE  (B6I1A4), 
NAPA_ECOSM  (B1LKV2), NAPA_ECOUT  (Q1R9L3), NAPA_ECTM1  (A4XWM0), 
NAPA_EDWI9  (C5B7B9), NAPA_ESCF3  (B7LJU7), NAPA_GLAP5  (B8F7K2), 
NAPA_HAEDU  (Q7VPJ7), NAPA_HAEI8  (Q4QNJ6), NAPA_HAHCH  (Q2SGV7), 
NAPA_HELHP  (Q7VJT5), NAPA_HISS1  (Q0I5G9), NAPA_HISS2  (B0URQ3), 
NAPA_LEPCP  (B1Y6A6), NAPA_MANSM  (Q65Q72), NAPA_METS4  (B0UCB6), 
NAPA_NAUPA  (B9L8L4), NAPA_NITSB  (A6Q604), NAPA_PARPN  (Q56350), 
NAPA_PARXL  (Q13I15), NAPA_PASMU  (Q9CKL8), NAPA_PECAS  (Q6D5Z2), 
NAPA_PECCP  (C6DK59), NAPA_PSEA8  (B7UX15), NAPA_PSEAB  (Q02IZ4), 
NAPA_PSEAE  (Q9I4G3), NAPA_PSEP7  (A6V924), NAPA_PSYIN  (A1SWQ0), 
NAPA_RALPJ  (B2UBL7), NAPA_RHIME  (Q92Z36), NAPA_RHOPB  (Q21AR4), 
NAPA_SACD2  (Q21PN1), NAPA_SALA4  (B5EYU5), NAPA_SALAR  (A9MJZ6), 
NAPA_SALCH  (Q57M92), NAPA_SALDC  (B5FNQ2), NAPA_SALEP  (B5R233), 
NAPA_SALG2  (B5RC85), NAPA_SALHS  (B4TAT3), NAPA_SALNS  (B4SYT3), 
NAPA_SALPA  (Q5PI61), NAPA_SALPB  (A9N5G2), NAPA_SALPC  (C0Q0P2), 
NAPA_SALPK  (B5BDZ4), NAPA_SALSV  (B4TPE6), NAPA_SALTI  (Q8Z570), 
NAPA_SALTY  (Q8ZNH6), NAPA_SERP5  (A8GHJ4), NAPA_SHEDO  (Q12P44), 
NAPA_SHEHH  (B0TSW5), NAPA_SHIB3  (B2TV30), NAPA_SHIBS  (Q31Z29), 
NAPA_SHIDS  (Q32I06), NAPA_SHIF8  (Q0T2R8), NAPA_SHIFL  (Q83QV0), 
NAPA_SHISS  (Q3Z001), NAPA_STUS1  (A4VJ11), NAPA_STUST  (Q3HS05), 
NAPA_SYMTH  (Q67QZ1), NAPA_VIBA3  (B7VRL0), NAPA_VIBC1  (A7N7J3), 
NAPA_VIBC3  (A5EZX9), NAPA_VIBCH  (Q9KLR4), NAPA_VIBCM  (C3LVU3), 
NAPA_VIBPA  (Q87GW6), NAPA_VIBVU  (Q8D623), NAPA_VIBVY  (Q7MD44), 
NAPA_WOLSU  (Q7M962), NAPA_YERE8  (A1JL26), NAPA_YERP3  (A7FG75), 
NAPA_YERPA  (Q1C5S8), NAPA_YERPB  (B2K970), NAPA_YERPE  (Q8ZCF3), 
NAPA_YERPG  (A9QZL3), NAPA_YERPN  (Q1CK03), NAPA_YERPP  (A4TMK8), 
NAPA_YERPS  (Q668I0), NAPA_YERPY  (B1JSJ0), NARB_SHEFN  (O33732), 
NARB_SYNE7  (P39458), NARB_SYNY3  (P73448), NARG_BACSU  (P42175), 
NARG_ECOLI  (P09152), NARG_HALMT  (I3R9M9), NARG_MYCTO  (P9WJQ2), 
NARG_MYCTU  (P9WJQ3), NARX_MYCTO  (P9WJQ0), NARX_MYCTU  (P9WJQ1), 
NARZ_ECOLI  (P19319), NASA_KLEOX  (Q06457), NASC_BACSU  (P42434), 
PHSA_SALTY  (P37600), PSRA_WOLSU  (P31075), SRDA_MESS1  (A0A0A8X0K1), 
Y006_METJA  (Q60314), YNFF_ECOLI  (P77783)
» more

UniProtKB/Swiss-Prot
False negative sequences		 41 sequences 

AHY_SYNAC   (Q71EW5), ARRA_CHRAT  (Q5Y818), ARRA_SHESA  (Q7WTU0), 

BISC_CERSP  (P54934), BISC_ECOLI  (P20099), CLRA_IDEDE  (P60068), 
DDHA_RHOSU  (Q8GPG4), DSTOR_CERSP (Q57366), DSTOR_RHOCA (Q52675), 
FDHL_BACSU  (Q795Y4), NAPA_DESDA  (P81186), NAPA_HAEIE  (A5UAE1), 
NAPA_LARHH  (C1D9G3), NAPA_PARM1  (Q2W3T1), NAPA_PARME  (Q93HX3), 
NAPA_SHEON  (Q8EIJ1), NASA_HALMT  (I3R634), PCRA_DECAR  (Q47CW6), 
QRCB_NITV2  (Q72E84), SERA_THASE  (Q9S1H0), TORA_ECO57  (P58360), 
TORA_ECOL6  (Q8CW73), TORA_ECOLI  (P33225), TORA_PASMU  (Q9CK41), 
TORA_SALTI  (Q8Z2M4), TORA_SALTY  (Q8ZKZ7), TORA_SHEMA  (O87948), 
TORA_SHEON  (Q8EHI9), TORA_VIBCH  (Q9KRF0), TORA_VIBPA  (Q87QI7), 
TORA_VIBVU  (Q8D8S3), TORA_VIBVY  (Q7MLQ2), TORZ_ECO57  (P58362), 
TORZ_ECOLI  (P46923), TORZ_HAEIN  (P44798), TTRA_ARCFU  (O30078), 
TTRA_SALTY  (Q9Z4S6), YJGC_BACSU  (O34720), YNFE_ECOLI  (P77374), 
YOAE_BACSU  (C0SP82), YYAE_BACSU  (P37519)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

NARG_BRASZ  (P85097)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			14 sequences
			


			
KR510_HUMAN (Q6L8G5), KR511_HUMAN (Q6L8G4), KRA51_HUMAN (Q6L8H4), 

			
KRA52_HUMAN (Q701N4), KRA54_HUMAN (Q6L8H1), KRA55_HUMAN (Q701N2), 
KRA56_HUMAN (Q6L8G9), KRA57_HUMAN (Q6L8G8), KRA58_HUMAN (O75690), 
KRUC_SHEEP  (P26372), MCT11_ARATH (O49435), NUOG2_RHIME (P56914), 
OR59A_DROME (P81923), POB3_EREGS  (Q756X6)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			22 PDB
			


			pdb_00001aa6; pdb_00001fdi; pdb_00001fdo; pdb_00001h0h; pdb_00001kqf; pdb_00001kqg; pdb_00001ogy; pdb_00001q16; pdb_00001r27; pdb_00001siw; pdb_00001y4z; pdb_00001y5i; 
			
				pdb_00001y5l; pdb_00001y5n; pdb_00002iv2; pdb_00002nya; pdb_00003egw; pdb_00003ir5; pdb_00003ir7; pdb_00003ml1; pdb_00003o5a; pdb_00007z0t
			
			

			» more