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PROSITE entry PS00572


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PURL: https://purl.expasy.org/prosite/signature/PS00572

Direct ScanProsite submission
General information about the entry

Entry name [info] GLYCOSYL_HYDROL_F1_1
Accession [info] PS00572
Entry type [info] PATTERN
Date [info] 01-DEC-1991 CREATED;
01-DEC-1992 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00495
Associated ProRule [info] PRU10055

Name and characterization of the entry

Description [info] Glycosyl hydrolases family 1 active site.
Pattern [info] 
[LIVMFSTC]-[LIVFYS]-[LIV]-[LIVMST]-E-N-G-[LIVMFAR]-[CSAGN].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 175 in 172 different sequences
Number of true positive hits 110 in 107 different sequences
Number of 'unknown' hits 0
Number of false positive hits 65 in 65 different sequences
Number of false negative sequences 100
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 62.86 %
Recall (true positives / (true positives + false negatives)) 52.38 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Site [info] active_site at position 5
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 107 sequences 

ABGA_CLOLO  (Q46130), ARBB_DICCH  (P26206), ASCB_ECOLI  (P24240), 

BGAL_PYRWO  (O52629), BGAL_SACS2  (P22498), BGAL_SACSH  (P50388), 
BGAL_SULAC  (P14288), BGL1B_PHACH (Q25BW4), BGL29_ORYSJ (A3C053), 
BGL34_ARATH (Q8GRX1), BGL35_ARATH (Q3ECS3), BGL37_ARATH (Q9C5C2), 
BGL38_ARATH (P37702), BGL45_ARATH (O80689), BGL46_ARATH (O80690), 
BGL47_ARATH (Q9SVS1), BGLA_ACET2  (P26208), BGLA_BACSU  (P42973), 
BGLA_ECOLI  (Q46829), BGLA_ENTAG  (Q59437), BGLA_NIACI  (Q03506), 
BGLA_PAEPO  (P22073), BGLA_THEMA  (Q08638), BGLA_THENE  (P0C946), 
BGLA_THENN  (B9K7M5), BGLB_ECOLI  (P11988), BGLB_PAEPO  (P22505), 
BGLB_THEBI  (P38645), BGLC_BACSU  (P42403), BGLFU_BIFBR (P94248), 
BGLH_BACSU  (P40740), BGLS_AGRSA  (P12614), BGLS_CALSA  (P10482), 
BGLS_TRIRP  (P26204), BGLT_TRIRP  (P26205), CASB_KLEOX  (Q48409), 
COX1_OSTNU  (Q9B840), GH1A_CALOW  (E4Q361), GMUD_BACSU  (O05508), 
HGGL1_MAIZE (P49235), HGGL2_MAIZE (Q41761), HGGL_SECCE  (Q9FYS3), 
HGL1A_WHEAT (Q1XIR9), HGL1B_WHEAT (Q1XH05), HGL1C_WHEAT (Q1XH04), 
HGL1D_WHEAT (D5MTF8), LACG2_STRPN (Q97QL9), LACG2_STRR6 (Q8DPP6), 
LACG_CLOAB  (Q97EZ2), LACG_LACAI  (P50977), LACG_LACCA  (P14696), 
LACG_LACCB  (B3W7I3), LACG_LACLL  (P11546), LACG_LACRH  (Q29ZJ1), 
LACG_LEPBD  (C7N8L9), LACG_STAA1  (A7X569), LACG_STAA2  (A6U3R9), 
LACG_STAA3  (Q2FEU3), LACG_STAA8  (Q2G2D5), LACG_STAA9  (A5IUX8), 
LACG_STAAB  (Q2YYJ9), LACG_STAAC  (Q5HE16), LACG_STAAE  (A6QJ33), 
LACG_STAAM  (P67767), LACG_STAAN  (P67768), LACG_STAAR  (Q6GEP0), 
LACG_STAAS  (Q6G7C5), LACG_STAAT  (A8YYF6), LACG_STAAU  (P11175), 
LACG_STAAW  (P67769), LACG_STAEQ  (Q5HM41), LACG_STAES  (Q8CNF8), 
LACG_STAHJ  (Q4L868), LACG_STRA3  (Q8E4S2), LACG_STREM  (B4U1G6), 
LACG_STRGC  (Q9EV38), LACG_STRMU  (P50978), LACG_STRP1  (Q99Y18), 
LACG_STRP3  (P0DB40), LACG_STRP6  (Q5X9Y7), LACG_STRP8  (Q8NZE1), 
LACG_STRPB  (Q1J9V2), LACG_STRPC  (Q1JK01), LACG_STRPD  (Q1JEZ3), 
LACG_STRPF  (Q1J4Q7), LACG_STRPG  (A2RGE8), LACG_STRPJ  (B8ZQ59), 
LACG_STRPM  (Q48RC8), LACG_STRPQ  (P0DB41), LACG_STRS7  (C0MDS5), 
LACG_STRSV  (A3CPH0), LACG_STRU0  (B9DU98), LACG_STRZJ  (C1CEE7), 
LCTL_HUMAN  (Q6UWM7), LPH_HUMAN   (P09848), LPH_RABIT   (P09849), 
LPH_RAT (Q02401), LPH_SHEEP   (W5PLZ6), MYR1_SINAL  (P29737), 
MYR2_SINAL  (P29738), MYR3_SINAL  (P29092), MYRA_SINAL  (P29736), 
MYRO_BRANA  (Q00326), SFR2_ARATH  (Q93Y07), SFR2_ORYSJ  (Q8L6H7), 
VICHY_VICSN (A2SY66), Y997_RICBR  (Q1RHT6)
» more

UniProtKB/Swiss-Prot
False negative sequences		 100 sequences 

BAGBG_DALNI (A3RF67), BGL01_ARATH (Q3ECW8), BGL01_ORYSJ (Q5QMT0), 

BGL02_ARATH (Q9FMD8), BGL02_ORYSJ (B7F8N7), BGL03_ARATH (O65458), 
BGL03_ORYSJ (Q8RZL1), BGL04_ARATH (Q9ZUI3), BGL04_ORYSJ (Q5N863), 
BGL05_ARATH (Q8RXN9), BGL05_ORYSJ (Q5JK35), BGL06_ARATH (Q682B4), 
BGL06_ORYSJ (Q8L7J2), BGL07_ARATH (Q9LZJ1), BGL07_ORYSJ (Q75I93), 
BGL08_ARATH (Q67XN2), BGL08_ORYSJ (Q75I94), BGL09_ARATH (Q9STP4), 
BGL09_ORYSJ (B7ECS8), BGL10_ARATH (Q93ZI4), BGL10_ORYSJ (Q7F9K4), 
BGL11_ARATH (B3H5Q1), BGL11_ORYSJ (Q7XKV5), BGL12_ARATH (Q9FH03), 
BGL12_ORYSI (B8AVF0), BGL12_ORYSJ (Q7XKV4), BGL13_ARATH (Q9LU02), 
BGL13_ORYSJ (Q7XKV2), BGL14_ARATH (Q9SLA0), BGL14_ORYSJ (Q7XPY7), 
BGL15_ARATH (O64879), BGL15_ORYSJ (Q7XPY5), BGL16_ARATH (Q9M1D0), 
BGL16_ORYSJ (Q7XSK2), BGL17_ARATH (O64882), BGL17_ORYSJ (Q7XSK1), 
BGL18_ARATH (Q9SE50), BGL18_ORYSJ (Q7XSK0), BGL19_ARATH (Q9LIF9), 
BGL19_ORYSJ (Q0DIT2), BGL1A_PHACH (Q25BW5), BGL20_ARATH (Q84WV2), 
BGL20_ORYSJ (B9FHH2), BGL21_ARATH (Q9C525), BGL21_ORYSJ (Q60DY1), 
BGL22_ARATH (Q9C8Y9), BGL22_ORYSJ (Q60DX8), BGL23_ARATH (Q9SR37), 
BGL23_ORYSJ (Q6L597), BGL24_ARATH (Q9LKR7), BGL24_ORYSJ (Q5Z9Z0), 
BGL25_ARATH (O82772), BGL25_ORYSJ (Q0DA21), BGL26_ARATH (O64883), 
BGL26_ORYSJ (A3BMZ5), BGL27_ARATH (Q9M1D1), BGL27_ORYSJ (Q84YK7), 
BGL28_ARATH (Q4V3B3), BGL28_ORYSJ (Q7EXZ4), BGL29_ARATH (Q8GXT2), 
BGL30_ARATH (Q9M1C9), BGL30_ORYSJ (Q0J0N4), BGL31_ARATH (Q9FLU9), 
BGL31_ORYSJ (B7F7K7), BGL32_ARATH (Q9FLU8), BGL32_ORYSJ (Q0J0G2), 
BGL33_ARATH (O48779), BGL33_ORYSJ (Q0J0G1), BGL34_ORYSJ (Q339X2), 
BGL35_ORYSJ (Q53NF0), BGL36_ARATH (Q9C8K1), BGL38_ORYSJ (Q2QSR8), 
BGL39_ARATH (Q3E8E5), BGL40_ARATH (Q9FZE0), BGL41_ARATH (Q9FIU7), 
BGL42_ARATH (Q9FIW4), BGL43_ARATH (Q9LV34), BGL44_ARATH (Q9LV33), 
BGLC_OLEEU  (Q8GVD0), FURH_VIBFR  (Q75W17), GBA3_CAVPO  (P97265), 
GBA3_HUMAN  (Q9H227), GBA3_PONAB  (Q5RF65), GLU1_CARIP  (B6ZKM3), 
GLU2_CARIP  (B6ZKM4), GLU3_CARIP  (B6ZKM5), GLU9_CARIP  (B6ZKN1), 
HIUH_SOYBN  (Q8S3J3), KLOTB_HUMAN (Q86Z14), KLOTB_MOUSE (Q99N32), 
KLOT_HUMAN  (Q9UEF7), KLOT_MACFA  (Q8WP17), KLOT_MOUSE  (O35082), 
KLOT_RAT(Q9Z2Y9), LACG1_STRPN (Q97SA9), LACG1_STRR6 (Q8DQZ1), 
LCTL_MOUSE  (Q8K1F9), MYRO1_BREBR (Q95X01), RG1_RAUSE   (Q9SPP9), 
SG1_RAUSE   (Q8GU20)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

MYRO2_BREBR (P83179)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			65 sequences
			


			
ACH1_NEUCR  (P15937), AKR2A_ARATH (Q9SAR5), AKR2B_ARATH (Q29Q26), 

			
APT_PSYIN   (A1SX04), ATC4_YEAST  (Q12675), BAMC_ECOLI  (P0A903), 
BAMC_SHIFL  (P0A904), CH10_STRA3  (P63768), CH10_STRA5  (P63769), 
COX1_CHOBI  (P50668), COX1_CHOFU  (P50669), COX1_CHOOC  (P67793), 
COX1_CHOPI  (P67794), COX1_CHRKN  (Q9B229), CRTN_METSP  (Q4VKV1), 
FBIB_MYCLE  (Q9CCK2), GYRA_AMICL  (D5ECW5), GYRA_BRAHW  (C0R046), 
GYRA_CLOAB  (P94605), GYRA_HELPJ  (Q9ZLD9), GYRA_HELPY  (P48370), 
GYRA_STRP1  (Q9L7Q5), GYRA_STRP3  (P0DG02), GYRA_STRP6  (Q5XC58), 
GYRA_STRP8  (Q8P116), GYRA_STRPQ  (P0DG03), HFLX_FLAPJ  (A6H294), 
HMA9_ORYSJ  (A0A0P0X004), HT1_IXOHO   (Q5UB45), KDISB_DANRE (Q7T163), 
LAC3_ARATH  (Q56YT0), MAP11_CAEEL (P91859), MBB1A_DANRE (Q6DRL5), 
MZT1_ASPCL  (A1CQI3), MZT1_BOTFB  (A6S6H9), MZT1_COCIM  (Q1DRC2), 
MZT1_EMENI  (Q5BDL9), MZT1_SCLS1  (A7EXZ2), NCAP_INCAA  (Q6I7C0), 
NCAP_INCCA  (P08028), NCAP_INCJH  (Q9IMP6), NRNA_BACSU  (O34600), 
NSE1_XENTR  (Q6P881), OTNK_ACTSZ  (A6VKK5), OTNK_HAEIN  (P44093), 
PII2_ARATH  (Q5PP26), RGYR_THEMA  (O51934), RIMS1_HUMAN (Q86UR5), 
RIMS1_MOUSE (Q99NE5), RIMS1_RAT   (Q9JIR4), RIMS3_HUMAN (Q9UJD0), 
RPO2C_METVS (P41557), RUVC_MYCLE  (P40834), SC24C_HUMAN (P53992), 
SFSA_ACTPJ  (B0BSG6), SPTCS_HUMAN (Q96JI7), SSTT_STRA1  (Q3JZQ1), 
SSTT_STRA3  (Q8E3S4), SSTT_STRA5  (Q8DY58), UBP5_YEAST  (P39944), 
URED_PROM1  (A2C4R9), URED_PROMT  (Q46IY6), VINT_BPL2   (P42540), 
YDGC_BACSU  (P96701), YI31_SCHPO  (Q9HE12)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			100 PDB
			


			pdb_00001bga; pdb_00001bgg; pdb_00001cbg; pdb_00001dwa; pdb_00001dwf; pdb_00001dwg; pdb_00001dwh; pdb_00001dwi; pdb_00001dwj; pdb_00001e1e; pdb_00001e1f; pdb_00001e4i; 
			
				pdb_00001e4l; pdb_00001e4m; pdb_00001e4n; pdb_00001e55; pdb_00001e56; pdb_00001e6q; pdb_00001e6s; pdb_00001e6x; pdb_00001e70; pdb_00001e71; pdb_00001e72; pdb_00001e73; 
				pdb_00001gow; pdb_00001h49; pdb_00001hxj; pdb_00001myr; pdb_00001od0; pdb_00001oif; pdb_00001oim; pdb_00001oin; pdb_00001pbg; pdb_00001qox; pdb_00001tr1; pdb_00001uwi; 
				pdb_00001uwq; pdb_00001uwr; pdb_00001uws; pdb_00001uwt; pdb_00001uwu; pdb_00001uyq; pdb_00001uz1; pdb_00001v08; pdb_00001w3j; pdb_00001w9b; pdb_00001w9d; pdb_00002cbu; 
				pdb_00002cbv; pdb_00002ceq; pdb_00002cer; pdb_00002ces; pdb_00002cet; pdb_00002dga; pdb_00002j75; pdb_00002j77; pdb_00002j78; pdb_00002j79; pdb_00002j7b; pdb_00002j7c; 
				pdb_00002j7d; pdb_00002j7e; pdb_00002j7f; pdb_00002j7g; pdb_00002j7h; pdb_00002jal; pdb_00002jie; pdb_00002o9p; pdb_00002o9r; pdb_00002o9t; pdb_00002pbg; pdb_00002vrj; 
				pdb_00002wbg; pdb_00002wc3; pdb_00002wc4; pdb_00002wxd; pdb_00002xhy; pdb_00002z1s; pdb_00003aiq; pdb_00003air; pdb_00003ais; pdb_00003aiu; pdb_00003aiv; pdb_00003aiw; 
				pdb_00003pbg; pdb_00004eam; pdb_00004ean; pdb_00004gxp; pdb_00005ixe; pdb_00005n6s; pdb_00005n6t; pdb_00005ogz; pdb_00005oss; pdb_00006qwi; pdb_00006r4k; pdb_00007uz1; 
				pdb_00007uz2; pdb_00007z1i; pdb_00008ivy; pdb_00009iqb
			
			

			» more