PROSITE entry PS00598

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PURL: https://purl.expasy.org/prosite/signature/PS00598

Direct ScanProsite submission

General information about the entry

Entry name [info]	CHROMO_1
Accession [info]	PS00598
Entry type [info]	PATTERN
Date [info]	01-DEC-1991 CREATED; 01-JUL-1999 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00517

Name and characterization of the entry

Description [info]	Chromo domain signature.
Pattern [info]	[FYL]-x-[LIVMC]-[KR]-W-x-[GDNR]-[FYWLME]-x(5,6)-[ST]-W-[ESV]-[PSTDEN]- x(2,3)-[LIVMC].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.

Total number of hits	78 in 70 different sequences
Number of true positive hits	78 in 70 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	40
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	66.10 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	2
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

70 sequences

CBX1_HUMAN  (P83916), CBX1_MOUSE  (P83917), CBX2_HUMAN  (Q14781),

CBX2_MOUSE  (P30658), CBX3_HUMAN  (Q13185), CBX3_MOUSE  (P23198), 
CBX3_PONAB  (Q5R6X7), CBX4_HUMAN  (O00257), CBX4_MOUSE  (O55187), 
CBX5_HUMAN  (P45973), CBX5_MOUSE  (Q61686), CBX6_HUMAN  (O95503), 
CBX6_MOUSE  (Q9DBY5), CBX7_HUMAN  (O95931), CBX7_MOUSE  (Q8VDS3), 
CBX7_RAT(P60889), CBX8_HUMAN  (Q9HC52), CBX8_MOUSE  (Q9QXV1), 
CBXH1_CAEEL (G5EET5), CDY1_HUMAN  (Q9Y6F8), CDY2_HUMAN  (Q9Y6F7), 
CDYL2_HUMAN (Q8N8U2), CDYL2_MOUSE (Q9D5D8), CDYL_HUMAN  (Q9Y232), 
CDYL_MOUSE  (Q9WTK2), CDYL_RAT(Q6AYK9), CEC1_CAEEL  (P34618), 
CEC3_CAEEL  (P45968), CHD1_BOMMO  (A9X4T1), CHD1_CHICK  (B6ZLK2), 
CHD1_DROME  (Q7KU24), CHD1_HUMAN  (O14646), CHD1_MOUSE  (P40201), 
CHD1_YEAST  (P32657), CHD2_HUMAN  (O14647), CHD2_MOUSE  (E9PZM4), 
CHD3_HUMAN  (Q12873), CHD4_HUMAN  (Q14839), CHD4_MOUSE  (Q6PDQ2), 
CHP1_SCHPO  (Q10103), CLR4_SCHPO  (O60016), CMT1_ARATH  (O49139), 
CMT1_ORYSJ  (A0A0P0VUY4), CMT2_ORYSJ  (Q5KQL9), CMT3_ARATH  (Q94F88), 
HP1_DROME   (P05205), HP1_DROVI   (P29227), HRP3_SCHPO  (O14139), 
LHP1_ARATH  (Q946J8), LHP1_ORYSJ  (Q339W7), LHP1_SOLLC  (Q944N1), 
MPP8_HUMAN  (Q99549), MPP8_MOUSE  (Q3TYA6), MPP8_RAT(G3V8T1), 
PC_DROME(P26017), SUV39_DROME (P45975), SUV39_DROPS (Q294B9), 
SUV91_BOVIN (Q2NL30), SUV91_HUMAN (O43463), SUV91_MOUSE (O54864), 
SUV91_PONAB (Q5RB81), SUV92_BOVIN (Q32PH7), SUV92_CHICK (Q5F3W5), 
SUV92_HUMAN (Q9H5I1), SUV92_MACFA (Q4R3E0), SUV92_MOUSE (Q9EQQ0), 
SUV92_XENTR (Q28CQ7), SV91A_DANRE (Q6DGD3), SWI6_CRYNH  (J9VQZ0), 
SWI6_SCHPO  (P40381)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

40 sequences

CBXH2_CAEEL (G5EDE2), CEC4_CAEEL  (Q19972), CHD3_CAEEL  (Q22516),

CHD3_DROME  (O16102), CHD5_HUMAN  (Q8TDI0), CHD6_HUMAN  (Q8TD26), 
CHD7_CHICK  (Q06A37), CHD7_HUMAN  (Q9P2D1), CHD7_MOUSE  (A2AJK6), 
CHD8_DANRE  (B0R0I6), CHD8_HUMAN  (Q9HCK8), CHD8_MOUSE  (Q09XV5), 
CHD8_RAT(Q9JIX5), CHD8_XENTR  (B5DE69), CHD9_HUMAN  (Q3L8U1), 
CHD9_MOUSE  (Q8BYH8), CHDM_DROME  (O97159), CHP2_SCHPO  (O42934), 
CHR4_ARATH  (F4KBP5), CHR5_ARATH  (F4IV99), CHR7_ARATH  (F4JTF6), 
CMT1_MAIZE  (Q9AXT8), CMT2_ARATH  (Q94F87), CMT2_MAIZE  (Q9ARI6), 
CMT3_MAIZE  (Q8LPU5), CMT3_ORYSJ  (C0SQ89), DCAF1_HUMAN (Q9Y4B6), 
DCAF1_MOUSE (Q80TR8), DMT5_CRYNH  (J9VI03), ELF1_SCHPO  (O14134), 
HRP1_SCHPO  (Q9US25), LE418_CAEEL (G5EBZ4), MSL3_DROME  (P50536), 
MSL3_DROVI  (Q9NBL2), NEW1_YEAST  (Q08972), PKL_ARATH   (Q9S775), 
RHINO_DROME (Q7JXA8), SR43C_ARATH (O22265), SR43C_ORYSJ (Q8LSQ2), 
SUV91_XENLA (Q6NRE8)

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PDB
[Detailed view]

95 PDB

pdb_00001ap0; pdb_00001g6z; pdb_00001guw; pdb_00001kna; pdb_00001kne; pdb_00001pdq; pdb_00001pfb; pdb_00001q3l; pdb_00002b2t; pdb_00002b2u; pdb_00002b2v; pdb_00002b2w; pdb_00002b2y; pdb_00002d9u; pdb_00002dnt; pdb_00002dnv; pdb_00002dy7; pdb_00002dy8; pdb_00002ee1; pdb_00002h1e; pdb_00002k1b; pdb_00002k28; pdb_00002kvm; pdb_00002l11; pdb_00002l12; pdb_00002l1b; pdb_00002mj8; pdb_00002rsn; pdb_00002rso; pdb_00002rvl; pdb_00002rvm; pdb_00002rvn; pdb_00003dm1; pdb_00003f2u; pdb_00003fdt; pdb_00003g7l; pdb_00003gv6; pdb_00003h91; pdb_00003i8z; pdb_00003i90; pdb_00003i91; pdb_00003lwe; pdb_00003mts; pdb_00003mwy; pdb_00003qo2; pdb_00003r93; pdb_00003svm; pdb_00003tzd; pdb_00004hae; pdb_00004mn3; pdb_00004nw2; pdb_00004o42; pdb_00004o9i; pdb_00004x3k; pdb_00004x3s; pdb_00004x3t; pdb_00004x3u; pdb_00005afw; pdb_00005ejw; pdb_00005epj; pdb_00005epk; pdb_00005epl; pdb_00005eq0; pdb_00005jjz; pdb_00005o9g; pdb_00006asz; pdb_00006at0; pdb_00006d07; pdb_00006ftx; pdb_00006g0l; pdb_00006mha; pdb_00006q3m; pdb_00006ryr; pdb_00006ryu; pdb_00006v2d; pdb_00006v2h; pdb_00006v2r; pdb_00006v2s; pdb_00006v3n; pdb_00006v41; pdb_00006v8w; pdb_00007m5u; pdb_00007n27; pdb_00007nkx; pdb_00007tn2; pdb_00007vyw; pdb_00007vz2; pdb_00008sii; pdb_00008sp6; pdb_00008umg; pdb_00008uxq; pdb_00008xag; pdb_00009gd1; pdb_00009gd2; pdb_00009gd3
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