PROSITE entry PS00598

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS00598
Entry name [info]	CHROMO_1
Accession [info]	PS00598
Entry type [info]	PATTERN
Date [info]	01-DEC-1991 CREATED; 01-JUL-1999 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00517

Name and characterization of the entry

Description [info]	Chromo domain signature.
Pattern [info]	[FYL]-x-[LIVMC]-[KR]-W-x-[GDNR]-[FYWLME]-x(5,6)-[ST]-W-[ESV]-[PSTDEN]- x(2,3)-[LIVMC].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	78 in 70 different sequences
Number of true positive hits	78 in 70 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	40
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	66.10 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	2
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

70 sequences

CBX1_HUMAN  (P83916), CBX1_MOUSE  (P83917), CBX2_HUMAN  (Q14781),

CBX2_MOUSE  (P30658), CBX3_HUMAN  (Q13185), CBX3_MOUSE  (P23198), 
CBX3_PONAB  (Q5R6X7), CBX4_HUMAN  (O00257), CBX4_MOUSE  (O55187), 
CBX5_HUMAN  (P45973), CBX5_MOUSE  (Q61686), CBX6_HUMAN  (O95503), 
CBX6_MOUSE  (Q9DBY5), CBX7_HUMAN  (O95931), CBX7_MOUSE  (Q8VDS3), 
CBX7_RAT(P60889), CBX8_HUMAN  (Q9HC52), CBX8_MOUSE  (Q9QXV1), 
CBXH1_CAEEL (G5EET5), CDY1_HUMAN  (Q9Y6F8), CDY2_HUMAN  (Q9Y6F7), 
CDYL2_HUMAN (Q8N8U2), CDYL2_MOUSE (Q9D5D8), CDYL_HUMAN  (Q9Y232), 
CDYL_MOUSE  (Q9WTK2), CDYL_RAT(Q6AYK9), CEC1_CAEEL  (P34618), 
CEC3_CAEEL  (P45968), CHD1_BOMMO  (A9X4T1), CHD1_CHICK  (B6ZLK2), 
CHD1_DROME  (Q7KU24), CHD1_HUMAN  (O14646), CHD1_MOUSE  (P40201), 
CHD1_YEAST  (P32657), CHD2_HUMAN  (O14647), CHD2_MOUSE  (E9PZM4), 
CHD3_HUMAN  (Q12873), CHD4_HUMAN  (Q14839), CHD4_MOUSE  (Q6PDQ2), 
CHP1_SCHPO  (Q10103), CLR4_SCHPO  (O60016), CMT1_ARATH  (O49139), 
CMT1_ORYSJ  (A0A0P0VUY4), CMT2_ORYSJ  (Q5KQL9), CMT3_ARATH  (Q94F88), 
HP1_DROME   (P05205), HP1_DROVI   (P29227), HRP3_SCHPO  (O14139), 
LHP1_ARATH  (Q946J8), LHP1_ORYSJ  (Q339W7), LHP1_SOLLC  (Q944N1), 
MPP8_HUMAN  (Q99549), MPP8_MOUSE  (Q3TYA6), MPP8_RAT(G3V8T1), 
PC_DROME(P26017), SUV39_DROME (P45975), SUV39_DROPS (Q294B9), 
SUV91_BOVIN (Q2NL30), SUV91_HUMAN (O43463), SUV91_MOUSE (O54864), 
SUV91_PONAB (Q5RB81), SUV92_BOVIN (Q32PH7), SUV92_CHICK (Q5F3W5), 
SUV92_HUMAN (Q9H5I1), SUV92_MACFA (Q4R3E0), SUV92_MOUSE (Q9EQQ0), 
SUV92_XENTR (Q28CQ7), SV91A_DANRE (Q6DGD3), SWI6_CRYNH  (J9VQZ0), 
SWI6_SCHPO  (P40381)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

40 sequences

CBXH2_CAEEL (G5EDE2), CEC4_CAEEL  (Q19972), CHD3_CAEEL  (Q22516),

CHD3_DROME  (O16102), CHD5_HUMAN  (Q8TDI0), CHD6_HUMAN  (Q8TD26), 
CHD7_CHICK  (Q06A37), CHD7_HUMAN  (Q9P2D1), CHD7_MOUSE  (A2AJK6), 
CHD8_DANRE  (B0R0I6), CHD8_HUMAN  (Q9HCK8), CHD8_MOUSE  (Q09XV5), 
CHD8_RAT(Q9JIX5), CHD8_XENTR  (B5DE69), CHD9_HUMAN  (Q3L8U1), 
CHD9_MOUSE  (Q8BYH8), CHDM_DROME  (O97159), CHP2_SCHPO  (O42934), 
CHR4_ARATH  (F4KBP5), CHR5_ARATH  (F4IV99), CHR7_ARATH  (F4JTF6), 
CMT1_MAIZE  (Q9AXT8), CMT2_ARATH  (Q94F87), CMT2_MAIZE  (Q9ARI6), 
CMT3_MAIZE  (Q8LPU5), CMT3_ORYSJ  (C0SQ89), DCAF1_HUMAN (Q9Y4B6), 
DCAF1_MOUSE (Q80TR8), DMT5_CRYNH  (J9VI03), ELF1_SCHPO  (O14134), 
HRP1_SCHPO  (Q9US25), LE418_CAEEL (G5EBZ4), MSL3_DROME  (P50536), 
MSL3_DROVI  (Q9NBL2), NEW1_YEAST  (Q08972), PKL_ARATH   (Q9S775), 
RHINO_DROME (Q7JXA8), SR43C_ARATH (O22265), SR43C_ORYSJ (Q8LSQ2), 
SUV91_XENLA (Q6NRE8)

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PDB
[Detailed view]

95 PDB

1AP0; 1G6Z; 1GUW; 1KNA; 1KNE; 1PDQ; 1PFB; 1Q3L; 2B2T; 2B2U; 2B2V; 2B2W; 2B2Y; 2D9U; 2DNT; 2DNV; 2DY7; 2DY8; 2EE1; 2H1E; 2K1B; 2K28; 2KVM; 2L11; 2L12; 2L1B; 2MJ8; 2RSN; 2RSO; 2RVL; 2RVM; 2RVN; 3DM1; 3F2U; 3FDT; 3G7L; 3GV6; 3H91; 3I8Z; 3I90; 3I91; 3LWE; 3MTS; 3MWY; 3QO2; 3R93; 3SVM; 3TZD; 4HAE; 4MN3; 4NW2; 4O42; 4O9I; 4X3K; 4X3S; 4X3T; 4X3U; 5AFW; 5EJW; 5EPJ; 5EPK; 5EPL; 5EQ0; 5JJZ; 5O9G; 6ASZ; 6AT0; 6D07; 6FTX; 6G0L; 6MHA; 6Q3M; 6RYR; 6RYU; 6V2D; 6V2H; 6V2R; 6V2S; 6V3N; 6V41; 6V8W; 7M5U; 7N27; 7NKX; 7TN2; 7VYW; 7VZ2; 8SII; 8SP6; 8UMG; 8UXQ; 8XAG; 9GD1; 9GD2; 9GD3
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