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PROSITE entry PS00601


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General information about the entry

Entry name [info] IRF_1
Accession [info] PS00601
Entry type [info] PATTERN
Date [info] 01-DEC-1991 CREATED;
01-JUL-1998 DATA UPDATE;
03-MAY-2023 INFO UPDATE.
PROSITE Doc. [info] PDOC00522

Name and characterization of the entry

Description [info] IRF tryptophan pentad repeat DNA-binding domain signature.
Pattern [info] 
W-x-[DNH]-x(5)-[LIVF]-x-[IV]-P-W-x-H-x(9,10)-[DE]-x(2)-[LIVF]-F-[KRQ]-x-
[WR]-A.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2023_02 which contains 569'516 sequence entries.


Total number of hits 29 in 29 different sequences
Number of true positive hits 29 in 29 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 5
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 85.29 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 29 sequences 

IRF1_BOVIN  (Q3SZP0    ), IRF1_CHICK  (Q90876    ), IRF1_HUMAN  (P10914    ), 

IRF1_MOUSE  (P15314    ), IRF1_PIG    (A0FIN4    ), IRF1_RAT    (P23570    ), 
IRF2_CHICK  (Q98925    ), IRF2_HUMAN  (P14316    ), IRF2_MOUSE  (P23906    ), 
IRF2_SIGHI  (Q8R4E0    ), IRF3_CHICK  (Q90643    ), IRF3_HUMAN  (Q14653    ), 
IRF3_MOUSE  (P70671    ), IRF3_PIG    (Q764M6    ), IRF4_HUMAN  (Q15306    ), 
IRF4_MOUSE  (Q64287    ), IRF5_BOVIN  (Q58DJ0    ), IRF5_HUMAN  (Q13568    ), 
IRF5_MOUSE  (P56477    ), IRF6_BOVIN  (Q08DD6    ), IRF6_HUMAN  (O14896    ), 
IRF6_MOUSE  (P97431    ), IRF7_HUMAN  (Q92985    ), IRF7_MOUSE  (P70434    ), 
IRF8_CHICK  (Q90871    ), IRF8_HUMAN  (Q02556    ), IRF8_MOUSE  (P23611    ), 
IRF9_HUMAN  (Q00978    ), IRF9_MOUSE  (Q61179    )
» more

UniProtKB/Swiss-Prot
False negative sequences		 5 sequences 

IRF3_BOVIN  (Q4JF28    ), VIRF1_HHV8P (F5HF68    ), VIRF2_HHV8P (Q2HR71    ), 

VIRF3_HHV8P (F5HIC6    ), VIRF4_HHV8P (Q2HR73    )
» more

PDB
[Detailed view]		 16 PDB

1IF1; 1IRF; 1IRG; 1T2K; 2DLL; 2IRF; 2O61; 2O6G; 2PI0; 3QU3; 3QU6; 6TD4; 7JM4; 7O56; 7OGS; 7OOT
» more