PROSITE entry PS00601
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General information about the entry
| PURL [info] | https://purl.expasy.org/prosite/signature/PS00601 |
| Entry name [info] | IRF_1 |
| Accession [info] | PS00601 |
| Entry type [info] | PATTERN |
| Date [info] |
01-DEC-1991 CREATED;
01-JUL-1998 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00522 |
Name and characterization of the entry
| Description [info] | IRF tryptophan pentad repeat DNA-binding domain signature. |
| Pattern [info] |
W-x-[DNH]-x(5)-[LIVF]-x-[IV]-P-W-x-H-x(9,10)-[DE]-x(2)-[LIVF]-F-[KRQ]-x- [WR]-A. |
Numerical results [info]
| Total number of hits | 29 in 29 different sequences |
| Number of true positive hits | 29 in 29 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 5 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 85.29 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes, Eukaryotic viruses |
| Maximum number of repetitions [info] | 1 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
29 sequences
IRF1_BOVIN (Q3SZP0), IRF1_CHICK (Q90876), IRF1_HUMAN (P10914), IRF1_MOUSE (P15314), IRF1_PIG(A0FIN4), IRF1_RAT(P23570), IRF2_CHICK (Q98925), IRF2_HUMAN (P14316), IRF2_MOUSE (P23906), IRF2_SIGHI (Q8R4E0), IRF3_CHICK (Q90643), IRF3_HUMAN (Q14653), IRF3_MOUSE (P70671), IRF3_PIG(Q764M6), IRF4_HUMAN (Q15306), IRF4_MOUSE (Q64287), IRF5_BOVIN (Q58DJ0), IRF5_HUMAN (Q13568), IRF5_MOUSE (P56477), IRF6_BOVIN (Q08DD6), IRF6_HUMAN (O14896), IRF6_MOUSE (P97431), IRF7_HUMAN (Q92985), IRF7_MOUSE (P70434), IRF8_CHICK (Q90871), IRF8_HUMAN (Q02556), IRF8_MOUSE (P23611), IRF9_HUMAN (Q00978), IRF9_MOUSE (Q61179)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
5 sequences
IRF3_BOVIN (Q4JF28), VIRF1_HHV8P (F5HF68), VIRF2_HHV8P (Q2HR71), VIRF3_HHV8P (F5HIC6), VIRF4_HHV8P (Q2HR73)» more |
| PDB [Detailed view] |
17 PDB
1IF1; 1IRF; 1IRG; 1T2K; 2DLL; 2IRF; 2O61; 2O6G; 2PI0; 3QU3; 3QU6; 6TD4; 7JM4; 7O56; 7OGS; 7OOT; 7RH2 » more |