 |
|
| Entry: PS00606 |
General information about the entry
| Entry name [info] | B_KETOACYL_SYNTHASE |
| Accession [info] | PS00606 |
| Entry type [info] | PATTERN |
| Date [info] |
01-DEC-1991 CREATED;
01-APR-2006 DATA UPDATE; 07-APR-2021 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00529 |
| Associated ProRule [info] | PRU10022 |
Name and characterization of the entry
| Description [info] | Beta-ketoacyl synthases active site. |
| Pattern [info] |
G-{A}-{KGR}-x(2)-[LIVMFTAP]-{R}-x-[AGC]-C-[STA](2)-[STAG]-x(2)-{LI}-
[LIVMF].
|
Numerical results [info]
| Total number of hits | 346 in 336 different sequences |
| Number of true positive hits | 337 in 327 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 9 in 9 different sequences |
| Number of false negative sequences | 14 |
| Number of 'partial' sequences | 2 |
| Precision (true positives / (true positives + false positives)) | 97.40 % |
| Recall (true positives / (true positives + false negatives)) | 96.01 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes, Prokaryotes (Bacteria) |
| Maximum number of repetitions [info] | 2 |
| Site [info] | active_site at position 9 |
| Version [info] | 2 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
327 sequences
5MOAS_ASPTN (Q0CRQ5 ), ACE1_MAGO7 (G4MVZ2 ), ACRA_ASPA1 (A0A1L9WQM9), ACRS2_ALTAL (R4WH05 ), ACTI1_STRCO (Q02059 ), ACTS3_ALTAL (D9N1A1 ), ACUA_ASPA1 (A0A1L9WN37), ADAA_ASPNC (A2QX22 ), ADAA_ASPNG (G3KLH6 ), ADRD_PENRO (A0A1Y0BRF1), ADRD_PENRW (B6HV32 ), AF161_ALTAL (V5Y0F7 ), AFLA_ASPPU (Q8TGA2 ), AFOE_EMENI (Q5BEJ6 ), AFVB_ASPFN (B8N8R0 ), AGPKS_PAEDI (A0A411PQP9), ALB1_ASPFU (Q4WZA8 ), ALBA_ASPBC (A0A1L9UCG2), ALBA_ASPNA (G3XLL5 ), ALBA_ASPNC (A2QUI2 ), ALNA_EMENI (C8VJR7 ), ALT1_ALTAL (A0A3G9H990), ALT5_ALTSO (Q5KTM9 ), ANDM_EMEVA (A0A097ZPE0), APDA_EMENI (Q5ATG8 ), APF5_GIBF5 (S0DL59 ), APTA_EMENI (Q5B0D0 ), AR283_ARTOA (G1XU04 ), ARMB_ARMGA (A0A2H3CTK0), ARMB_ARMME (I3ZNU9 ), ARMB_ARMOS (A0A284RE13), ASC5_DIDFA (A0A5C1RD96), ASC7_DIDFA (A0A5C1RDA3), ASCC_ACREG (A0A455R5P9), AT325_ASPTN (Q0D159 ), ATNF_EMENI (Q5AV00 ), ATX_ASPTN (Q0CJ59 ), AURA_CALAK (A0A0M4L8I7), AUSA_EMENI (Q5ATJ7 ), AZAB_ASPNA (G3XMD1 ), AZPB2_ASPTN (Q0CF73 ), BET1_PLEBE (A0A0C6E0I7), BIK1_GIBF5 (S0DZM7 ), BOA6_BOTFB (B1GVX7 ), BUAA_ASPBU (A0A411L027), CALA_PENDC (A0A1V6PAF7), CAZM_CHAGB (A0A0K0MCJ4), CCSA_ASPCL (A1CLY8 ), CEM1_YEAST (P39525 ), CHG2_CHAGB (Q2HEW5 ), CITS_MONPU (Q65Z23 ), CITS_MONRU (A0A161CEU9), CLA3_CLACD (A0A125R003), CM3B_CORMM (G3J453 ), CNSI_PENEN (A0A0A2JW91), CPAS_ASPOZ (B6F209 ), CTB1_CERBT (A0A2G5IC96), CTB1_CERNC (Q6DQW3 ), CTVA_ASPTN (Q0C9L7 ), CURS2_ASPTE (L7XAV2 ), DEP5_ALTBR (D2E9X0 ), DEP5_FUSLA (A0A0N0DCA3), DHC5_ALTCI (A0A0N7D745), DPASA_ARTSH (P9WEX0 ), DPCHA_COLHI (A0A1B7YCC9), DPFGA_GIBZE (I1RL11 ), DPMAA_METAN (P9WEX6 ), DPMPA_MACPH (K2QVI8 ), EASB_EMENI (Q5BA83 ), ELCA_PHANO (Q0UI00 ), EQXS_FUSHE (S4W172 ), EQXS_GIBF5 (S0DS59 ), ERYA1_SACER (Q03131 ), ERYA2_SACER (Q03132 ), ERYA3_SACER (Q03133 ), EUPA_PHOSX (A0A4P8GHJ1), FABB_BUCAI (P57193 ), FABB_BUCAP (Q8KA28 ), FABB_BUCBP (Q89AY4 ), FABB_ECOL6 (P0A954 ), FABB_ECOLI (P0A953 ), FABB_HAEIN (P43710 ), FABB_PSEAB (Q02K94 ), FABF_BACSU (O34340 ), FABF_COXBU (Q83E37 ), FABF_ECO57 (P0AAI7 ), FABF_ECOL6 (P0AAI6 ), FABF_ECOLI (P0AAI5 ), FABF_RHIME (P56902 ), FABF_SHIFL (P0AAI8 ), FABF_STAAC (Q5HHA1 ), FABF_STAAM (Q99VA6 ), FABF_STAAN (Q7A6F8 ), FABF_STAAR (Q6GIA3 ), FABF_STAAS (Q6GAU2 ), FABF_STAAU (Q5TKS0 ), FABF_STAAW (Q8NXE1 ), FABF_SYNY3 (P73283 ), FABF_VIBCH (Q9KQH9 ), FABF_VIBHA (P55338 ), FAS2_CANAX (P43098 ), FAS2_CANPC (G8BAW7 ), FAS2_EMEND (P78615 ), FAS2_LACKL (Q765N2 ), FAS2_PENPA (P15368 ), FAS2_SCHPO (Q10289 ), FAS2_YEAST (P19097 ), FAS_ANSAN (P36189 ), FAS_BOVIN (Q71SP7 ), FAS_CHICK (P12276 ), FAS_HUMAN (P49327 ), FAS_MOUSE (P19096 ), FAS_RAT (P12785 ), FGNA_ASPFU (Q4WKW9 ), FLUP_ASPFN (B8NYX0 ), FMAB_ASPFU (Q4WAY3 ), FSA1_FUSSF (A0A0E4AZP0), FSDS_FUSHE (Q5SBL6 ), FSL1_GIBZE (I1S166 ), FSR1_GIBF5 (S0DTP6 ), FUB1_FUSO4 (A0A0D2YG10), FUB1_GIBF5 (S0DRI1 ), FUB1_GIBM7 (W7MT31 ), FUJ1_GIBF5 (S0EET5 ), FUM1_GIBM7 (W7LKX1 ), FUS1_GIBF5 (S0EEY3 ), FUS1_GIBM7 (W7MLD7 ), FUSA1_GIBZE (I1RVD8 ), GEDC_ASPTN (Q0CCY3 ), GLOL_GLAL2 (S3D9F1 ), GRA1_CLAGR (E9KMQ2 ), GRA9_GIBZE (I1R9A6 ), GSFA_PENAE (D7PI15 ), HEXA_DOTSN (M2YJJ3 ), HIMA_ASPJA (A0A2Z5TM64), HPM3_HYPSB (B3FWS8 ), HPS1_DOTSN (M2YKT6 ), ICCA_TALVA (A0A482N9V7), KAS1_STRCM (P41175 ), KAS1_STRCN (Q02578 ), KAS1_STRCO (P23155 ), KAS1_STRGA (P16538 ), KAS1_STRHA (Q05356 ), KAS1_STRRM (P43678 ), KAS1_STRVN (P16540 ), KASC1_ARATH (P52410 ), KASC1_HORVU (P23902 ), KASC2_ARATH (Q9C9P4 ), KASM_ARATH (Q8L3X9 ), LCSC_PURLI (A0A179H0J7), LOVB_ASPTE (Q9Y8A5 ), LOVB_ASPTN (Q0C8M3 ), LOVF_ASPTE (Q9Y7D5 ), LOVF_ASPTN (Q0C8L6 ), MCAS_MYCBO (Q02251 ), MLCA_PENCI (Q8J0F7 ), MLCB_PENCI (Q8J0F5 ), MLNS_PHANO (A0A0A0RM07), MOKA_MONPI (Q3S2T9 ), MOKB_MONPI (Q3S2U6 ), MPAC2_PENBR (A0A0B5KU17), MPAC_PENBR (F1DBA9 ), MPAC_PENRF (W6QL47 ), MPAS_CLAUC (A0A0R8YWJ7), MSAS_PENPA (P22367 ), MSL3_MYCTU (A0A089QRB9), MSL7_MYCBO (Q7TXK8 ), MSL7_MYCMM (B2HIL7 ), MYCA_BACIU (Q9R9J1 ), MYCA_MYCTT (G2Q9A5 ), NODE_RHILT (P04684 ), NODE_RHILV (P04683 ), NODE_RHIME (P06230 ), NODE_RHIS3 (P72331 ), NOE4_RHIML (P06231 ), NSCA_ARTBC (D4AWH3 ), NSCA_ARTGP (E4V2N2 ), NSCA_ARTOC (C5FM57 ), NSCA_ASPFU (Q4WA61 ), NSCA_NEOFI (A1D8I9 ), NSCA_TRIEC (F2PWS5 ), NSCA_TRIRC (F2T0M0 ), NSCA_TRIT1 (F2S6Z9 ), NSCA_TRIVH (D4CZZ2 ), OL56_STRAT (Q07017 ), OPS1_BEAB2 (J4UHQ6 ), ORSA_EMENI (Q5AUX1 ), OTA1_ASPC5 (A0A1R3RGK0), OTA1_ASPNC (A2R6H1 ), OXSM_BOVIN (Q0VCA7 ), OXSM_HUMAN (Q9NWU1 ), OXSM_MOUSE (Q9D404 ), PATK_ASPCL (A1CFL8 ), PATK_PENEN (A0A075TRC0), PFMAE_PESFW (W3X7U2 ), PHAS_MYCBO (Q7TVK8 ), PHAS_MYCBP (A1KQG0 ), PHAS_MYCTA (A5U9F4 ), PHAS_MYCTO (P9WQE8 ), PHAS_MYCTU (P9WQE9 ), PHNA_PENHR (A0A142C799), PIG15_CLAP2 (M1WG96 ), PIKA1_STRVZ (Q9ZGI5 ), PIKA2_STRVZ (Q9ZGI4 ), PIKA3_STRVZ (Q9ZGI3 ), PIKA4_STRVZ (Q9ZGI2 ), PKFA_EMENI (Q5B8A0 ), PKGA_EMENI (Q5AXA9 ), PKHA_EMENI (Q5BBP8 ), PKIB_EMENI (Q5B7V0 ), PKS10_DICDI (B0G103 ), PKS12_GIBZE (I1RF58 ), PKS12_MYCTU (I6XD69 ), PKS13_DICDI (Q559A9 ), PKS13_MYCTU (I6X8D2 ), PKS14_DICDI (Q558Y6 ), PKS15_MYCTU (P96284 ), PKS16_DICDI (Q869W9 ), PKS17_DICDI (Q869X2 ), PKS18_DICDI (Q54TW0 ), PKS19_DICDI (Q54T36 ), PKS19_MAGO7 (G4N296 ), PKS19_PHANO (A0A0H4ADX3), PKS1_DICDI (Q55E72 ), PKS1_ELSFA (A7UMW1 ), PKS1_METAF (A0A0B4FTU6), PKS1_METAQ (A0A2U8NEV6), PKS1_METAS (A0A2U8NET4), PKS1_METBS (A0A0B4ESU9), PKS1_METGA (A0A0B4G9F9), PKS1_METMF (A0A0B4H4F0), PKS1_METRA (E9F646 ), PKS1_SARSH (A5PHD6 ), PKS1_ZYMTI (F9XMW3 ), PKS21_DICDI (B0G138 ), PKS22_DICDI (Q54QD3 ), PKS23_DICDI (Q54QD1 ), PKS24_DICDI (Q54KU5 ), PKS25_DICDI (Q54KU3 ), PKS27_ASPFN (B8MYS6 ), PKS27_DICDI (Q54G30 ), PKS28_DICDI (B0G170 ), PKS29_DICDI (Q54FQ3 ), PKS2_COCH4 (N4WHA7 ), PKS2_DICDI (Q55DM7 ), PKS2_METAF (A0A0B4FLB2), PKS2_METAQ (E9EHG2 ), PKS2_METBS (A0A0B4H8J1), PKS2_METGA (A0A0B4I1L1), PKS2_METMF (A0A0B4I1J8), PKS2_METRA (E9ET39 ), PKS30_DICDI (Q54FQ2 ), PKS31_DICDI (Q54FQ1 ), PKS32_DICDI (Q54FP8 ), PKS33_DICDI (Q54FN7 ), PKS34_DICDI (Q54FN2 ), PKS38_DICDI (Q54FD2 ), PKS39_DICDI (Q54FC8 ), PKS3_DICDI (Q55CN6 ), PKS40_DICDI (Q54ED7 ), PKS41_DICDI (Q54ED6 ), PKS42_DICDI (Q54D44 ), PKS44_DICDI (Q54B51 ), PKS5_DICDI (Q86JI5 ), PKS5_MYCS2 (A0R1E8 ), PKS5_MYCTU (O53901 ), PKS6_DICDI (B0G0Z9 ), PKS7_DICDI (B0G100 ), PKS81_PSEFD (M3A326 ), PKS8_DICDI (B0G101 ), PKS9_DICDI (Q86AE3 ), PKSJ_BACSU (P40806 ), PKSL_BACSU (Q05470 ), PKSM_BACSU (P40872 ), PKSN_BACSU (O31782 ), PKSR_BACSU (O31784 ), PPSA_MYCBO (Q7TXM0 ), PPSA_MYCTO (P9WQE6 ), PPSA_MYCTU (P9WQE7 ), PPSB_ASPOR (Q2UB00 ), PPSB_MYCBO (Q7TXL9 ), PPSB_MYCTO (P9WQE4 ), PPSB_MYCTU (P9WQE5 ), PPSC_MYCBO (Q7TXL8 ), PPSC_MYCTU (P96202 ), PPSD_MYCBO (Q7TXL7 ), PPSD_MYCTO (P9WQE2 ), PPSD_MYCTU (P9WQE3 ), PPSE_MYCBO (Q7TXL6 ), PPSE_MYCTO (P9WQE0 ), PPSE_MYCTU (P9WQE1 ), PRHL_PENBI (A0A1E1FFN8), PRLS_FUNXX (A0A089FSA4), PSOA_ASPFU (Q4WAZ9 ), PTAA_PESFW (A0A067XNI2), PYR2_ASPFU (Q4WLD4 ), PYTA_ASPTE (P9WEZ4 ), PYTA_ASPTN (Q0CZH1 ), RADS2_FLOCH (C5H882 ), RDC1_METCM (B3FWT6 ), SDGA_EMENI (A0A1U8QN18), SOL1_ALTSO (D7UQ44 ), SORB_HYPJQ (G0R6S9 ), SPKS1_STRTC (A0A384XH94), SQHKS_PHOSM (A0A3G1DJF3), SRDA_NEUCR (Q7SHI6 ), STBA_STABI (A0A193PS74), STCJ_EMENI (Q00681 ), STHA_PHANO (Q0UK48 ), STLB_DICDI (Q54FI3 ), SUBA_METRA (E9F5E7 ), TAS1_MAGO7 (G4N137 ), TERA_ASPTN (Q0D1N9 ), TPCC_ASPFU (Q4WQZ5 ), TROPA_TALSN (B8M9J9 ), TRT4_ASPTN (Q0C8A4 ), TWMB_TALWO (A0A2L0P0K3), USTP_USTVR (A0A1B5L6A0), VALA_ASPTE (P9WEV0 ), VDTA1_BYSSP (A0A443HK81), VIRA_HYPVG (G9N4B2 ), VRTA_PENAE (D7PHZ2 ), W4931_FUSPC (K3VA96 ), WA_EMENI (Q03149 ), YANA_ASPNA (G3Y419 ), ZEA1_GIBZE (A0A098D6U0), ZEA2_GIBZE (A0A098D8A0)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
14 sequences
BEKAS_PSEAE (Q9HYV7 ), KASA_MYCBO (P63455 ), KASA_MYCLE (Q9CBS7 ), KASA_MYCTE (H8ESN0 ), KASA_MYCTO (P9WQD8 ), KASA_MYCTU (P9WQD9 ), KASB_MYCBO (P63457 ), KASB_MYCLE (O69473 ), KASB_MYCTO (P9WQD6 ), KASB_MYCTU (P9WQD7 ), ORYA_ASPOR (Q2TXF0 ), PIGJ_SERS3 (Q5W262 ), PKS26_DICDI (Q54IX3 ), PKS45_DICDI (Q54B49 )» more |
| UniProtKB/Swiss-Prot 'Partial' sequences |
2 sequences
FAS_CAPHI (P08757 ), FAS_RABIT (P07855 ) |
| UniProtKB/Swiss-Prot False positive sequences |
9 sequences
GLPB_HAEDU (Q7VM49 ), KDSB_MYXXD (Q1DDB3 ), MDH_PSYIN (A1SRP8 ), MNMG_ERYLH (Q2N6I8 ), NEUA_BOVIN (Q3SZM5 ), NEUA_HUMAN (Q8NFW8 ), NEUA_PONAB (Q5R6R5 ), PUS5_ORYSJ (Q0DST9 ), Y1105_ARATH (O04086 )» more |
| PDB [Detailed view] |
71 PDB
1B3N; 1DD8; 1E5M; 1FJ4; 1FJ8; 1G5X; 1H4F; 1KAS; 1TQY; 1W0I; 2AQ7; 2AQB; 2BUH; 2BUI; 2BYW; 2BYX; 2BYY; 2BYZ; 2BZ3; 2BZ4; 2C9H; 2CDH; 2GFW; 2GFY; 2GQD; 2HG4; 2IWY; 2IWZ; 2IX4; 2PFF; 2QO3; 2UV8; 2VB7; 2VB8; 2VB9; 2VBA; 2VKZ; 3HHD; 3HMJ; 4JRH; 4JRM; 4LS5; 4LS6; 4LS7; 4LS8; 4NA1; 5BP1; 5KOF; 5MY0; 5MY2; 6C9U; 6FIJ; 6FIK; 6JSH; 6JSI; 6KOG; 6OKC; 6OKF; 6OKG; 6OLT; 6QL5; 6QL6; 6QL7; 6QL9; 6ROP; 6TA1; 6U5V; 6U5W; 6WC7; 7CPX; 7CPY » more |
View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission