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Entry: PS00606

General information about the entry

Entry name [info] B_KETOACYL_SYNTHASE
Accession [info] PS00606
Entry type [info] PATTERN
Date [info] 01-DEC-1991 CREATED;
01-APR-2006 DATA UPDATE;
02-JUN-2021 INFO UPDATE.
PROSITE Doc. [info] PDOC00529
Associated ProRule [info] PRU10022

Name and characterization of the entry

Description [info] Beta-ketoacyl synthases active site.
Pattern [info] 
G-{A}-{KGR}-x(2)-[LIVMFTAP]-{R}-x-[AGC]-C-[STA](2)-[STAG]-x(2)-{LI}-
[LIVMF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2021_03 which contains 565'254 sequence entries.


Total number of hits 355 in 344 different sequences
Number of true positive hits 346 in 335 different sequences
Number of 'unknown' hits 0
Number of false positive hits 9 in 9 different sequences
Number of false negative sequences 14
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 97.46 %
Recall (true positives / (true positives + false negatives)) 96.11 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Site [info] active_site at position 9
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 335 sequences 

5MOAS_ASPTN (Q0CRQ5    ), ACE1_MAGO7  (G4MVZ2    ), ACRA_ASPA1  (A0A1L9WQM9), 

ACRS2_ALTAL (R4WH05    ), ACTI1_STRCO (Q02059    ), ACTS3_ALTAL (D9N1A1    ), 
ACUA_ASPA1  (A0A1L9WN37), ADAA_ASPNC  (A2QX22    ), ADAA_ASPNG  (G3KLH6    ), 
ADRD_PENRO  (A0A1Y0BRF1), ADRD_PENRW  (B6HV32    ), AF161_ALTAL (V5Y0F7    ), 
AFLA_ASPPU  (Q8TGA2    ), AFOE_EMENI  (Q5BEJ6    ), AFVB_ASPFN  (B8N8R0    ), 
AGPKS_PAEDI (A0A411PQP9), ALB1_ASPFU  (Q4WZA8    ), ALBA_ASPBC  (A0A1L9UCG2), 
ALBA_ASPNA  (G3XLL5    ), ALBA_ASPNC  (A2QUI2    ), ALNA_EMENI  (C8VJR7    ), 
ALT1_ALTAL  (A0A3G9H990), ALT5_ALTSO  (Q5KTM9    ), ANDM_EMEVA  (A0A097ZPE0), 
APDA_EMENI  (Q5ATG8    ), APF5_GIBF5  (S0DL59    ), APTA_EMENI  (Q5B0D0    ), 
AR283_ARTOA (G1XU04    ), ARMB_ARMGA  (A0A2H3CTK0), ARMB_ARMME  (I3ZNU9    ), 
ARMB_ARMOS  (A0A284RE13), ASC5_DIDFA  (A0A5C1RD96), ASC7_DIDFA  (A0A5C1RDA3), 
ASCC_ACREG  (A0A455R5P9), AT325_ASPTN (Q0D159    ), ATNF_EMENI  (Q5AV00    ), 
ATNH_ARTSZ  (A0A455LLX1), ATX_ASPTN   (Q0CJ59    ), AURA_CALAK  (A0A0M4L8I7), 
AUSA_EMENI  (Q5ATJ7    ), AZAB_ASPNA  (G3XMD1    ), AZPB2_ASPTN (Q0CF73    ), 
BET1_PLEBE  (A0A0C6E0I7), BIK1_GIBF5  (S0DZM7    ), BOA6_BOTFB  (B1GVX7    ), 
BUAA_ASPBU  (A0A411L027), CALA_PENDC  (A0A1V6PAF7), CAZM_CHAGB  (A0A0K0MCJ4), 
CCSA_ASPCL  (A1CLY8    ), CEM1_YEAST  (P39525    ), CHEA_CHAGB  (Q2HEW5    ), 
CITS_MONPU  (Q65Z23    ), CITS_MONRU  (A0A161CEU9), CLA3_CLACD  (A0A125R003), 
CLZ14_COCLU (A0A345BJN0), CM3B_CORMM  (G3J453    ), CNSI_PENEN  (A0A0A2JW91), 
CPAS_ASPOZ  (B6F209    ), CTB1_CERBT  (A0A2G5IC96), CTB1_CERNC  (Q6DQW3    ), 
CTVA_ASPTN  (Q0C9L7    ), CURS2_ASPTE (L7XAV2    ), DEP5_ALTBR  (D2E9X0    ), 
DEP5_FUSLA  (A0A0N0DCA3), DHC5_ALTCI  (A0A0N7D745), DPASA_ARTSH (P9WEX0    ), 
DPCHA_COLHI (A0A1B7YCC9), DPFGA_GIBZE (I1RL11    ), DPMAA_METAN (P9WEX6    ), 
DPMPA_MACPH (K2QVI8    ), EASB_EMENI  (Q5BA83    ), ELCA_PHANO  (Q0UI00    ), 
EQXS_FUSHE  (S4W172    ), EQXS_GIBF5  (S0DS59    ), ERYA1_SACER (Q03131    ), 
ERYA2_SACER (Q03132    ), ERYA3_SACER (Q03133    ), EUPA_PHOSX  (A0A4P8GHJ1), 
FABB_BUCAI  (P57193    ), FABB_BUCAP  (Q8KA28    ), FABB_BUCBP  (Q89AY4    ), 
FABB_ECOL6  (P0A954    ), FABB_ECOLI  (P0A953    ), FABB_HAEIN  (P43710    ), 
FABB_PSEAB  (Q02K94    ), FABF_BACSU  (O34340    ), FABF_COXBU  (Q83E37    ), 
FABF_ECO57  (P0AAI7    ), FABF_ECOL6  (P0AAI6    ), FABF_ECOLI  (P0AAI5    ), 
FABF_RHIME  (P56902    ), FABF_SHIFL  (P0AAI8    ), FABF_STAAC  (Q5HHA1    ), 
FABF_STAAM  (Q99VA6    ), FABF_STAAN  (Q7A6F8    ), FABF_STAAR  (Q6GIA3    ), 
FABF_STAAS  (Q6GAU2    ), FABF_STAAU  (Q5TKS0    ), FABF_STAAW  (Q8NXE1    ), 
FABF_SYNY3  (P73283    ), FABF_VIBCH  (Q9KQH9    ), FABF_VIBHA  (P55338    ), 
FAS2_CANAX  (P43098    ), FAS2_CANPC  (G8BAW7    ), FAS2_EMEND  (P78615    ), 
FAS2_LACKL  (Q765N2    ), FAS2_PENPA  (P15368    ), FAS2_SCHPO  (Q10289    ), 
FAS2_USTMA  (A0A0D1DNX1), FAS2_YEAST  (P19097    ), FAS_ANSAN   (P36189    ), 
FAS_BOVIN   (Q71SP7    ), FAS_CHICK   (P12276    ), FAS_HUMAN   (P49327    ), 
FAS_MOUSE   (P19096    ), FAS_RAT     (P12785    ), FGNA_ASPFU  (Q4WKW9    ), 
FLUP_ASPFN  (B8NYX0    ), FMAB_ASPFU  (Q4WAY3    ), FSA1_FUSSF  (A0A0E4AZP0), 
FSDS_FUSHE  (Q5SBL6    ), FSL1_GIBZE  (I1S166    ), FSR1_GIBF5  (S0DTP6    ), 
FUB1_FUSO4  (A0A0D2YG10), FUB1_GIBF5  (S0DRI1    ), FUB1_GIBM7  (W7MT31    ), 
FUJ1_GIBF5  (S0EET5    ), FUM1_GIBM7  (W7LKX1    ), FUS1_GIBF5  (S0EEY3    ), 
FUS1_GIBM7  (W7MLD7    ), FUSA1_GIBZE (I1RVD8    ), GEDC_ASPTN  (Q0CCY3    ), 
GLOL_GLAL2  (S3D9F1    ), GRA1_CLAGR  (E9KMQ2    ), GRA9_GIBZE  (I1R9A6    ), 
GSFA_PENAE  (D7PI15    ), HEXA_DOTSN  (M2YJJ3    ), HIMA_ASPJA  (A0A2Z5TM64), 
HPM3_HYPSB  (B3FWS8    ), HPS1_DOTSN  (M2YKT6    ), ICCA_TALVA  (A0A482N9V7), 
ILIA_NEOS2  (P0DO30    ), KAS1_STRCM  (P41175    ), KAS1_STRCN  (Q02578    ), 
KAS1_STRCO  (P23155    ), KAS1_STRGA  (P16538    ), KAS1_STRHA  (Q05356    ), 
KAS1_STRRM  (P43678    ), KAS1_STRVN  (P16540    ), KASC1_ARATH (P52410    ), 
KASC1_HORVU (P23902    ), KASC2_ARATH (Q9C9P4    ), KASM_ARATH  (Q8L3X9    ), 
LCSC_PURLI  (A0A179H0J7), LOVB_ASPTE  (Q9Y8A5    ), LOVB_ASPTN  (Q0C8M3    ), 
LOVF_ASPTE  (Q9Y7D5    ), LOVF_ASPTN  (Q0C8L6    ), MCAS_MYCBO  (Q02251    ), 
MLCA_PENCI  (Q8J0F7    ), MLCB_PENCI  (Q8J0F5    ), MLNS_PHANO  (A0A0A0RM07), 
MOKA_MONPI  (Q3S2T9    ), MOKB_MONPI  (Q3S2U6    ), MPAC2_PENBR (A0A0B5KU17), 
MPAC_PENBR  (F1DBA9    ), MPAC_PENRF  (W6QL47    ), MPAS_CLAUC  (A0A0R8YWJ7), 
MSAS_PENPA  (P22367    ), MSL3_MYCTU  (A0A089QRB9), MSL7_MYCBO  (Q7TXK8    ), 
MSL7_MYCMM  (B2HIL7    ), MYCA_BACIU  (Q9R9J1    ), MYCA_MYCTT  (G2Q9A5    ), 
NODE_RHILT  (P04684    ), NODE_RHILV  (P04683    ), NODE_RHIME  (P06230    ), 
NODE_RHIS3  (P72331    ), NOE4_RHIML  (P06231    ), NSCA_ARTBC  (D4AWH3    ), 
NSCA_ARTGP  (E4V2N2    ), NSCA_ARTOC  (C5FM57    ), NSCA_ASPFU  (Q4WA61    ), 
NSCA_NEOFI  (A1D8I9    ), NSCA_TRIEC  (F2PWS5    ), NSCA_TRIRC  (F2T0M0    ), 
NSCA_TRIT1  (F2S6Z9    ), NSCA_TRIVH  (D4CZZ2    ), NTNH_NECSZ  (A0A455M2Y3), 
NVFA_ASPN1  (A0A2I1BSV9), OL56_STRAT  (Q07017    ), OPS1_BEAB2  (J4UHQ6    ), 
ORSA_EMENI  (Q5AUX1    ), OTA1_ASPC5  (A0A1R3RGK0), OTA1_ASPNC  (A2R6H1    ), 
OXSM_BOVIN  (Q0VCA7    ), OXSM_HUMAN  (Q9NWU1    ), OXSM_MOUSE  (Q9D404    ), 
PATK_ASPCL  (A1CFL8    ), PATK_PENEN  (A0A075TRC0), PFMAE_PESFW (W3X7U2    ), 
PHAS_MYCBO  (Q7TVK8    ), PHAS_MYCBP  (A1KQG0    ), PHAS_MYCTA  (A5U9F4    ), 
PHAS_MYCTO  (P9WQE8    ), PHAS_MYCTU  (P9WQE9    ), PHNA_PENHR  (A0A142C799), 
PIG15_CLAP2 (M1WG96    ), PIKA1_STRVZ (Q9ZGI5    ), PIKA2_STRVZ (Q9ZGI4    ), 
PIKA3_STRVZ (Q9ZGI3    ), PIKA4_STRVZ (Q9ZGI2    ), PKFA_EMENI  (Q5B8A0    ), 
PKGA_EMENI  (Q5AXA9    ), PKHA_EMENI  (Q5BBP8    ), PKIB_EMENI  (Q5B7V0    ), 
PKS10_DICDI (B0G103    ), PKS12_GIBZE (I1RF58    ), PKS12_MYCTU (I6XD69    ), 
PKS13_DICDI (Q559A9    ), PKS13_MYCTU (I6X8D2    ), PKS14_DICDI (Q558Y6    ), 
PKS15_MYCTU (P96284    ), PKS16_DICDI (Q869W9    ), PKS17_DICDI (Q869X2    ), 
PKS18_DICDI (Q54TW0    ), PKS19_DICDI (Q54T36    ), PKS19_MAGO7 (G4N296    ), 
PKS19_PHANO (A0A0H4ADX3), PKS1_DICDI  (Q55E72    ), PKS1_ELSFA  (A7UMW1    ), 
PKS1_METAF  (A0A0B4FTU6), PKS1_METAQ  (A0A2U8NEV6), PKS1_METAS  (A0A2U8NET4), 
PKS1_METBS  (A0A0B4ESU9), PKS1_METGA  (A0A0B4G9F9), PKS1_METMF  (A0A0B4H4F0), 
PKS1_METRA  (E9F646    ), PKS1_SARSH  (A5PHD6    ), PKS1_ZYMTI  (F9XMW3    ), 
PKS21_DICDI (B0G138    ), PKS22_DICDI (Q54QD3    ), PKS23_DICDI (Q54QD1    ), 
PKS24_DICDI (Q54KU5    ), PKS25_DICDI (Q54KU3    ), PKS27_ASPFN (B8MYS6    ), 
PKS27_DICDI (Q54G30    ), PKS28_DICDI (B0G170    ), PKS29_DICDI (Q54FQ3    ), 
PKS2_COCH4  (N4WHA7    ), PKS2_DICDI  (Q55DM7    ), PKS2_METAF  (A0A0B4FLB2), 
PKS2_METAQ  (E9EHG2    ), PKS2_METBS  (A0A0B4H8J1), PKS2_METGA  (A0A0B4I1L1), 
PKS2_METMF  (A0A0B4I1J8), PKS2_METRA  (E9ET39    ), PKS30_DICDI (Q54FQ2    ), 
PKS31_DICDI (Q54FQ1    ), PKS32_DICDI (Q54FP8    ), PKS33_DICDI (Q54FN7    ), 
PKS34_DICDI (Q54FN2    ), PKS38_DICDI (Q54FD2    ), PKS39_DICDI (Q54FC8    ), 
PKS3_DICDI  (Q55CN6    ), PKS40_DICDI (Q54ED7    ), PKS41_DICDI (Q54ED6    ), 
PKS42_DICDI (Q54D44    ), PKS44_DICDI (Q54B51    ), PKS5_DICDI  (Q86JI5    ), 
PKS5_MYCS2  (A0R1E8    ), PKS5_MYCTU  (O53901    ), PKS6_DICDI  (B0G0Z9    ), 
PKS7_DICDI  (B0G100    ), PKS81_PSEFD (M3A326    ), PKS8_DICDI  (B0G101    ), 
PKS9_DICDI  (Q86AE3    ), PKSJ_BACSU  (P40806    ), PKSL_BACSU  (Q05470    ), 
PKSM_BACSU  (P40872    ), PKSN_BACSU  (O31782    ), PKSR_BACSU  (O31784    ), 
PPSA_MYCBO  (Q7TXM0    ), PPSA_MYCTO  (P9WQE6    ), PPSA_MYCTU  (P9WQE7    ), 
PPSB_ASPOR  (Q2UB00    ), PPSB_MYCBO  (Q7TXL9    ), PPSB_MYCTO  (P9WQE4    ), 
PPSB_MYCTU  (P9WQE5    ), PPSC_MYCBO  (Q7TXL8    ), PPSC_MYCTU  (P96202    ), 
PPSD_MYCBO  (Q7TXL7    ), PPSD_MYCTO  (P9WQE2    ), PPSD_MYCTU  (P9WQE3    ), 
PPSE_MYCBO  (Q7TXL6    ), PPSE_MYCTO  (P9WQE0    ), PPSE_MYCTU  (P9WQE1    ), 
PRHL_PENBI  (A0A1E1FFN8), PRLS_FUNXX  (A0A089FSA4), PSOA_ASPFU  (Q4WAZ9    ), 
PTAA_PESFW  (A0A067XNI2), PYR2_ASPFU  (Q4WLD4    ), PYTA_ASPTE  (P9WEZ4    ), 
PYTA_ASPTN  (Q0CZH1    ), PYVA_ASPV1  (A0A2V5GX43), RADS2_FLOCH (C5H882    ), 
RDC1_METCM  (B3FWT6    ), SDGA_EMENI  (A0A1U8QN18), SOL1_ALTSO  (D7UQ44    ), 
SORB_HYPJQ  (G0R6S9    ), SPKS1_STRTC (A0A384XH94), SQHKS_PHOSM (A0A3G1DJF3), 
SRDA_NEUCR  (Q7SHI6    ), STBA_STABI  (A0A193PS74), STCJ_EMENI  (Q00681    ), 
STHA_PHANO  (Q0UK48    ), STLB_DICDI  (Q54FI3    ), SUBA_METRA  (E9F5E7    ), 
TAS1_MAGO7  (G4N137    ), TERA_ASPTN  (Q0D1N9    ), THAG_BURTA  (Q2T4N1    ), 
TPCC_ASPFU  (Q4WQZ5    ), TROPA_TALSN (B8M9J9    ), TRT4_ASPTN  (Q0C8A4    ), 
TWMB_TALWO  (A0A2L0P0K3), USTP_USTVR  (A0A1B5L6A0), VALA_ASPTE  (P9WEV0    ), 
VDTA1_BYSSP (A0A443HK81), VIRA_HYPVG  (G9N4B2    ), VRTA_PENAE  (D7PHZ2    ), 
W4931_FUSPC (K3VA96    ), WA_EMENI    (Q03149    ), YANA_ASPNA  (G3Y419    ), 
ZEA1_GIBZE  (A0A098D6U0), ZEA2_GIBZE  (A0A098D8A0)
» more

UniProtKB/Swiss-Prot
False negative sequences		 14 sequences 

BEKAS_PSEAE (Q9HYV7    ), KASA_MYCBO  (P63455    ), KASA_MYCLE  (Q9CBS7    ), 

KASA_MYCTE  (H8ESN0    ), KASA_MYCTO  (P9WQD8    ), KASA_MYCTU  (P9WQD9    ), 
KASB_MYCBO  (P63457    ), KASB_MYCLE  (O69473    ), KASB_MYCTO  (P9WQD6    ), 
KASB_MYCTU  (P9WQD7    ), ORYA_ASPOR  (Q2TXF0    ), PIGJ_SERS3  (Q5W262    ), 
PKS26_DICDI (Q54IX3    ), PKS45_DICDI (Q54B49    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 2 sequences 

FAS_CAPHI   (P08757    ), FAS_RABIT   (P07855    )


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			9 sequences
			


			
GLPB_HAEDU  (Q7VM49    ), KDSB_MYXXD  (Q1DDB3    ), MDH_PSYIN   (A1SRP8    ), 

			
MNMG_ERYLH  (Q2N6I8    ), NEUA_BOVIN  (Q3SZM5    ), NEUA_HUMAN  (Q8NFW8    ), 
NEUA_PONAB  (Q5R6R5    ), PUS5_ORYSJ  (Q0DST9    ), Y1105_ARATH (O04086    )


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			71 PDB
			


			1B3N; 1DD8; 1E5M; 1FJ4; 1FJ8; 1G5X; 1H4F; 1KAS; 1TQY; 1W0I; 2AQ7; 2AQB; 
			
				2BUH; 2BUI; 2BYW; 2BYX; 2BYY; 2BYZ; 2BZ3; 2BZ4; 2C9H; 2CDH; 2GFW; 2GFY; 
				2GQD; 2HG4; 2IWY; 2IWZ; 2IX4; 2PFF; 2QO3; 2UV8; 2VB7; 2VB8; 2VB9; 2VBA; 
				2VKZ; 3HHD; 3HMJ; 4JRH; 4JRM; 4LS5; 4LS6; 4LS7; 4LS8; 4NA1; 5BP1; 5KOF; 
				5MY0; 5MY2; 6C9U; 6FIJ; 6FIK; 6JSH; 6JSI; 6KOG; 6OKC; 6OKF; 6OKG; 6OLT; 
				6QL5; 6QL6; 6QL7; 6QL9; 6ROP; 6TA1; 6U5V; 6U5W; 6WC7; 7CPX; 7CPY
			
			

			» more

				
	





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