PROSITE entry PS00623

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PURL: https://purl.expasy.org/prosite/signature/PS00623

Direct ScanProsite submission

General information about the entry

Entry name [info]	GMC_OXRED_1
Accession [info]	PS00623
Entry type [info]	PATTERN
Date [info]	01-JUN-1992 CREATED; 01-APR-2006 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00543

Name and characterization of the entry

Description [info]	GMC oxidoreductases signature 1.
Pattern [info]	[GA]-[RKNC]-x-[LIVW]-G(2)-[GST](2)-x-[LIVM]-[NH]-x(3)-[FYWA]-x(2)-[PAG]- x(5)-[DNESHQA].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.

Total number of hits	161 in 161 different sequences
Number of true positive hits	161 in 161 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	45
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	78.16 %

Comments [info]

Taxonomic range [info]	Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info]	1
Version [info]	2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

161 sequences

ALKJ_ECTOL  (Q00593), ALKJ_PSEPU  (Q9WWW2), ALOX1_KOMPC (F2QY27),

ALOX1_KOMPG (P04842), ALOX2_KOMPC (F2R038), ALOX2_KOMPG (C4R702), 
ALOX_CANBO  (Q00922), ALOX_PICAN  (P04841), ASC9_DIDFA  (A0A5C1RDA6), 
BETA1_CHRSD (Q1QXE1), BETA2_CHRSD (Q9L4K0), BETA_ACIAD  (Q6FDF9), 
BETA_ACIB3  (B7GYG5), BETA_ACIB5  (B7I895), BETA_ACIBC  (B2HV79), 
BETA_ACIBS  (B0VST3), BETA_ACIBY  (B0V945), BETA_AGRFC  (Q8UH55), 
BETA_BRUA4  (A6X2G7), BETA_BRUC2  (A9M9H8), BETA_BRUME  (Q8YFY2), 
BETA_BRUO2  (A5VPA6), BETA_BRUSI  (B0CKN4), BETA_BRUSU  (Q8G1Z8), 
BETA_BURA4  (B1Z034), BETA_BURCH  (A0B2F7), BETA_BURCJ  (B4EHJ2), 
BETA_BURCM  (Q0B711), BETA_BURL3  (Q39A44), BETA_BURM1  (A9AMZ9), 
BETA_BURMA  (Q62CH8), BETA_BURO0  (B1K707), BETA_BURO1  (Q1BQE2), 
BETA_BURP1  (Q3JLL7), BETA_BURPS  (Q63KK7), BETA_BURTA  (Q2T6D0), 
BETA_BURVG  (A4JJG6), BETA_CITK8  (A8AJN0), BETA_CROS8  (A7MFA8), 
BETA_ECO24  (A7ZI50), BETA_ECO27  (B7UJG4), BETA_ECO45  (B7MCD0), 
BETA_ECO55  (B7L439), BETA_ECO57  (Q8X6C6), BETA_ECO5E  (B5Z1R0), 
BETA_ECO8A  (B7M2V5), BETA_ECODH  (B1XE52), BETA_ECOHS  (A7ZWV4), 
BETA_ECOL5  (Q0TKW1), BETA_ECOL6  (Q8FKI9), BETA_ECOLC  (B1J0W6), 
BETA_ECOLI  (P17444), BETA_ECOLU  (B7N8L3), BETA_ECOSE  (B6I074), 
BETA_ECOSM  (B1LIJ7), BETA_ECOUT  (Q1RFM3), BETA_ECTM1  (A4XPI5), 
BETA_KLEP3  (B5Y008), BETA_KLEP7  (A6T613), BETA_PARP8  (B2JS89), 
BETA_PARPJ  (B2TCJ8), BETA_PARXL  (Q13NG7), BETA_PECAS  (Q6D6D9), 
BETA_PECCP  (C6DKY4), BETA_PHOPR  (Q6LGH5), BETA_PROMH  (B4EX94), 
BETA_PSE14  (Q48CM7), BETA_PSEA8  (B7V5R3), BETA_PSEAB  (Q02DZ0), 
BETA_PSEAE  (Q9HTJ2), BETA_PSEE4  (Q1IG70), BETA_PSEF5  (Q4K4K7), 
BETA_PSEFS  (C3K3D3), BETA_PSEP1  (A5WA97), BETA_PSEP7  (A6VEI3), 
BETA_PSEPF  (Q3K5H3), BETA_PSEPG  (B0KN19), BETA_PSEPK  (Q88CW6), 
BETA_PSESM  (Q88AE7), BETA_PSEU2  (Q4ZM63), BETA_RHIE6  (B3PTE0), 
BETA_RHIEC  (Q2KB43), BETA_RHIJ3  (Q1MJU4), BETA_RHILO  (Q985M5), 
BETA_RHILW  (B5ZUG2), BETA_RHIME  (P54223), BETA_RHIR8  (B9JBA2), 
BETA_SERP5  (A8GBX9), BETA_SHIF8  (Q0T7N0), BETA_SINFN  (C3MIE4), 
BETA_SINMW  (A6U6Y8), BETA_STAA1  (A7X6Z3), BETA_STAA2  (A6U4Z2), 
BETA_STAA3  (Q2FDP9), BETA_STAA8  (Q2FV11), BETA_STAA9  (A5IW37), 
BETA_STAAB  (Q2YWJ5), BETA_STAAC  (Q5HCU1), BETA_STAAE  (A6QK99), 
BETA_STAAM  (P60336), BETA_STAAN  (P60337), BETA_STAAR  (Q6GDJ1), 
BETA_STAAS  (Q6G664), BETA_STAAT  (A8Z5A4), BETA_STAAW  (Q8NUM0), 
BETA_STAEQ  (Q5HL11), BETA_STAES  (Q8CMY2), BETA_STAHJ  (Q4L9D7), 
BETA_STAS1  (Q4A0Q1), BETA_STAXY  (Q9X2M2), BETA_STRM5  (B4SHV9), 
BETA_STRMK  (B2FQ89), BETA_VIBC1  (A7N2P9), BETA_VIBVU  (Q8D3K2), 
BETA_VIBVY  (Q7MF12), BETA_XANAC  (Q8PPG8), BETA_XANC8  (Q4UYN5), 
BETA_XANCB  (B0RNU9), BETA_XANCP  (Q8P5D7), BETA_XANE5  (Q3BXK8), 
BETA_YERP3  (A7FKL6), BETA_YERPA  (Q1C932), BETA_YERPB  (B2K8U4), 
BETA_YERPE  (Q8ZGW0), BETA_YERPN  (Q1CFR7), BETA_YERPP  (A4TNP2), 
BETA_YERPS  (Q66D54), BETA_YERPY  (B1JSR0), CDH_PHACH   (Q01738), 
CHDH_HUMAN  (Q8NE62), CHDH_MOUSE  (Q8BJ64), CHDH_RAT(Q6UPE0), 
CHOD_BREST  (P22637), CHOD_STRS0  (P12676), CITC_MONPU  (A0A142PTM2), 
CITC_MONRU  (A0A161CEV4), DHGL_DROME  (P18173), DHGL_DROPS  (P18172), 
EO_BOMMO(H6AGY0), ERIK_HERER  (P0DO29), GMCH_MALS4  (M5EAX2), 
GMCH_MALSM  (Q5GMY3), GOX2_PENEN  (A0A0A2K2F6), GOX_ASPC5   (A0A1R3RM75), 
GOX_ASPNG   (P13006), GOX_PENAG   (P81156), GOX_TALFL   (Q92452), 
GOX_TALVA   (Q70FC9), MDL1_PRUDU  (O24243), MDL1_PRUSE  (P52706), 
MDL2_PRUDU  (Q945K2), MDL2_PRUSE  (O50048), MDL3_PRUSE  (P52707), 
MDLL_ARATH  (Q9SSM2), PNO_MICLT   (Q9AJD6), SDH_GLUOY   (Q47944), 
Y1279_MYCTO (P9WMV4), Y1279_MYCTU (P9WMV5), Y1310_MYCBO (P64264), 
Y4NJ_SINFN  (P55582), YTH2_RHOER  (P46371)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

45 sequences

4PADH_RHILO (Q988C9), AFLK_ASPPU  (Q12062), CGLYO_ARTG1 (H0QPM2),

CGLYO_MICSX (P0DXE4), CGLYO_MICTR (A0A0M2HFA3), CHOD_MYCTO  (P9WMV8), 
CHOD_MYCTU  (P9WMV9), CHOX_ARTGO  (Q7X2H8), FAO1_ARATH  (Q9ZWB9), 
FAO1_LOTJA  (B5WWZ8), FAO2_LOTJA  (B5WWZ9), FAO3_ARATH  (Q9LW56), 
FAO4A_ARATH (O65709), FAO4B_ARATH (Q94BP3), FAP_CHLRE   (A8JHB7), 
FAP_CHLVA   (A0A248QE08), FDHL_GLUJA  (M1VMF7), GADH1_PANCY (O34214), 
HTH_ARATH   (Q9S746), LIVQ_STRLV  (Q2MF66), MDL4_PRUSE  (O82784), 
MPDB_MYCAO  (Q3YAT3), NEOG_STRFR  (Q53U15), NINAG_DROME (Q9VGP2), 
P2OX_EMENI  (Q5B2E9), P2OX_LYOSH  (Q75ZP8), P2OX_PENSG  (Q8J136), 
P2OX_PHACH  (Q6QWR1), P2OX_PHLGI  (Q6UG02), P2OX_TRAHI  (P59097), 
P2OX_TRAPU  (Q5G234), P2OX_TRAVE  (P79076), P2OX_TRIMT  (Q8J2V8), 
PDH1_AGABI  (Q3L1D1), PDH1_AGACM  (V5NDL4), PDH1_AGAXA  (V5NC32), 
PDH1_LEUMG  (Q3L245), PDH2_LEUMG  (Q3L243), PDH3_LEUMG  (Q0R4L2), 
Y492_MYCTO  (P9WMV6), Y492_MYCTU  (P9WMV7), YL128_MIMIV (Q5UPK7), 
YL894_MIMIV (Q5UQZ1), YR135_MIMIV (Q5UPL2), YR832_MIMIV (Q5UQH9)

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PDB
[Detailed view]

46 PDB

1B4V; 1B8S; 1CBO; 1CC2; 1CF3; 1COY; 1GAL; 1GPE; 1IJH; 1JU2; 1KDG; 1MXT; 1N1P; 1N4U; 1N4V; 1N4W; 1NAA; 2GEW; 3B3R; 3B6D; 3CNJ; 3COX; 3GDN; 3GDP; 3GYI; 3GYJ; 3QVP; 3QVR; 4REK; 4U2L; 4U2S; 4U2T; 4XWR; 4XXG; 5EB4; 5EB5; 5HSA; 5I68; 5KWF; 5NIT; 5NIW; 6JBY; 6LQY; 6LR8; 7BWP; 7CGS
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