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PROSITE entry PS00626


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General information about the entry

Entry name [info] RCC1_2
Accession [info] PS00626
Entry type [info] PATTERN
Date [info] 01-JUN-1992 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00544

Name and characterization of the entry

Description [info] Regulator of chromosome condensation (RCC1) signature 2.
Pattern [info]
[LIVMFA]-[STAGC](2)-G-x-{TAV}-H-[STAGLI]-[LIVMFA]-{KI}-[LIVM].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 382 in 313 different sequences
Number of true positive hits 133 in 64 different sequences
Number of 'unknown' hits 2 in 2 different sequences
Number of false positive hits 247 in 247 different sequences
Number of false negative sequences 18
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 35.00 %
Recall (true positives / (true positives + false negatives)) 88.08 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 5
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
64 sequences

ALS2_DROME  (Q9VNZ8), ALS2_HUMAN  (Q96Q42), ALS2_MOUSE  (Q920R0), 
ALS2_PANTR  (Q5BIW4), ALS2_RAT(P0C5Y8), ATS1_YEAST  (P31386), 
FMP25_YEAST (Q08023), GEFC_DICDI  (Q8IS20), HERC1_HUMAN (Q15751), 
HERC2_DROME (Q9VR91), HERC2_HUMAN (O95714), HERC2_MOUSE (Q4U2R1), 
HERC3_HUMAN (Q15034), HERC4_HUMAN (Q5GLZ8), HERC4_MOUSE (Q6PAV2), 
HERC4_RAT   (Q5PQN1), HERC5_HUMAN (Q9UII4), HERC6_HUMAN (Q8IVU3), 
HERC6_MOUSE (F2Z461), HIW_DROME   (Q9NB71), MYCB2_DANRE (F1RD40), 
MYCB2_HUMAN (O75592), MYCB2_MOUSE (Q7TPH6), NEK9_XENLA  (Q7ZZC8), 
PRAF1_ARATH (Q947D2), RCBT1_HUMAN (Q8NDN9), RCBT1_MOUSE (Q6NXM2), 
RCBT2_HUMAN (O95199), RCBT2_MOUSE (Q99LJ7), RCBT2_PONAB (Q5RCZ7), 
RCBT2_RAT   (Q6P798), RCC1L_HUMAN (Q96I51), RCC1_CAEEL  (Q18211), 
RCC1_CANAX  (P52499), RCC1_DROME  (P25171), RCC1_HUMAN  (P18754), 
RCC1_MESAU  (P23800), RCC1_MOUSE  (Q8VE37), RCC1_SCHPO  (P28745), 
RCC1_XENLA  (P25183), RCC1_YEAST  (P21827), RCC2_DANRE  (Q6NYE2), 
RCC2_HUMAN  (Q9P258), RCC2_MOUSE  (Q8BK67), RCC2_XENLA  (Q52KW8), 
RCCD1_HUMAN (A6NED2), RCCD1_MACFA (Q4R828), RCCD1_MOUSE (Q8BTU7), 
RCCDA_DICDI (Q54X24), RCCDB_DICDI (P0C7G9), RPGRH_CAEEL (Q5DX34), 
RPGR_CANLF  (Q9N1T2), RPGR_HUMAN  (Q92834), RPGR_MOUSE  (Q9R0X5), 
RPM1_CAEEL  (Q17551), RUG3_ARATH  (Q9FJG9), SAF1_YEAST  (P38352), 
SPKUL_DICDI (Q8SSY6), SRGEF_BOVIN (Q3MHW0), SRGEF_HUMAN (Q9UGK8), 
SRGEF_MOUSE (Q80YD6), TIRA_DICDI  (Q54HT1), UVR8_ARATH  (Q9FN03), 
YF94_SCHPO  (O42645)
» more

UniProtKB/Swiss-Prot
False negative sequences
18 sequences

BTB1_SCHPO  (O74881), FBX24_HUMAN (O75426), FBX24_MACFA (Q4R327), 
FBX24_MOUSE (Q9D417), GACGG_DICDI (Q54VW7), IBTK_HUMAN  (Q9P2D0), 
IBTK_MOUSE  (Q6ZPR6), IBTK_XENLA  (Q6NRS1), NEK8_DANRE  (Q90XC2), 
NEK8_HUMAN  (Q86SG6), NEK8_MOUSE  (Q91ZR4), NEK8_RAT(D3ZGQ5), 
NEK9_HUMAN  (Q8TD19), NEK9_MOUSE  (Q8K1R7), POF9_SCHPO  (O74381), 
RCC1L_MOUSE (Q9CYF5), RCCDC_DICDI (Q54Q89), TITIN_MOUSE (A2ASS6)
» more

UniProtKB/Swiss-Prot
'Unknown' sequences
2 sequences

ATTY_CAEEL  (Q93703), YENB_YERET  (B6A880)

		
UniProtKB/Swiss-Prot
False positive sequences
247 sequences

095R_FRG3G  (Q6GZN0), ABRB_ABRPR  (Q06077), ACBM_ACTS5  (Q8RIS8), 
ACCD1_ROSS1 (A5UQC0), ACUK_AJECG  (C0NCM1), ACUK_AJECN  (A6R213), 
ACYP_PECAS  (Q6D6C4), ADPG1_ARATH (O23147), ADPG2_ARATH (Q8RY29), 
AGS_RHIRH   (P27875), AHPF_STAAM  (P66012), AHPF_STAAN  (P99118), 
AHPF_STAAR  (Q6GJR8), AHPF_STAAS  (Q6GC92), AHPF_STAAW  (P66013), 
ALAT_SCHPO  (Q10334), AQP1_RHIIR  (I3W9F6), AREL1_HUMAN (O15033), 
AREL1_MOUSE (Q8CHG5), ARK1_CAEEL  (G5EBZ8), AROA2_STRCO (Q9L213), 
AROC_LEIXX  (Q6AF97), AROC_STRMU  (Q8DUW1), AROC_STRP6  (Q5XCT6), 
AROC_STRP8  (Q8P1H5), AROC_STRPG  (A2RF78), AROC_STRSV  (A3CNV6), 
AROC_TROW8  (Q83HU6), AROC_TROWT  (Q83GD5), ARSB1_ECOLX (P08691), 
AT18C_ARATH (Q8GYD7), AT18D_ARATH (Q0WPK3), ATGT_SULTO  (Q975U5), 
ATTY_TRYCR  (P33447), AXE1_ASPAW  (Q92194), AXE1_ASPFI  (Q96W96), 
AXE1_ASPFU  (Q4WBW4), AXE1_ASPNC  (A2QZI3), AXE1_ASPTN  (Q0C8Z1), 
AXE1_NEOFI  (A1DBP9), BASB_HALS3  (B0R6I5), BCH_HAELA   (Q9SPK6), 
BOYB_DROME  (Q9VNP5), C508B_DICDI (Q54SK0), CLA2_CLACD  (A0A0Y0M151), 
CLH_DROME   (P29742), COBN_PSEAE  (Q9HZQ3), COPE2_ARATH (O64748), 
CSGE_ECO57  (P0AE97), CSGE_ECOL6  (P0AE96), CSGE_ECOLI  (P0AE95), 
CTAA_PARDP  (A1B8C2), CTAA_RUEPO  (Q5LRS1), CURS1_ASPTE (L7X8J4), 
CYLD_BOVIN  (Q1RMU2), DABA_HYDCU  (Q31HC3), DAPAT_NATTJ (B2A250), 
DDB1A_ARATH (Q9M0V3), DDB1B_ARATH (O49552), DDB1_ORYSJ  (Q6L4S0), 
DDB1_SOLCE  (Q6E7D1), DDB1_SOLLC  (Q6QNU4), DESA_SPHSK  (G2IJ05), 
DHC3_ALTCI  (A0A0N7D4P6), DLG5_HUMAN  (Q8TDM6), DLG5_MOUSE  (E9Q9R9), 
DNAJ_STRPN  (P95830), DNAJ_STRR6  (Q8CWT2), DTDA_HALS3  (B0R384), 
DTDA_HALSA  (Q9HS70), EGFL8_PIG   (A5A8Y8), EGTE_MYCTO  (Q7D515), 
EGTE_MYCTU  (O69668), EIF3E_YARLI (Q6C0Q2), ELCG_PHANO  (Q0UHZ8), 
ELP2_DROME  (Q7K4B3), FABH_STRLI  (Q9F6D4), FAP_CHLRE   (A8JHB7), 
GCSP_GLUOX  (Q5FRY0), GLGA2_NOSS1 (Q8Z0Q9), GLGA2_SYNY3 (P72623), 
GLGB_BURTA  (Q2T6R3), GOPC_HUMAN  (Q9HD26), GOPC_MOUSE  (Q8BH60), 
GOPC_PONAB  (Q5RD32), GOX_ASPNG   (P13006), GP183_RAT   (D4A7K7), 
GPMI_GLUOX  (Q5FU33), GPMI_RHOPA  (Q6NCX7), GPMI_STRCO  (Q9L214), 
GRA1_GIBZE  (A0A098D1P1), GRP1_PETHY  (P09789), HDA4_CAEEL  (O17323), 
HIS1_PROMM  (Q7V6G9), HIS4_DEIRA  (Q9RRJ5), HIS4_VIBCH  (Q9KSW9), 
HOX16_ORYSI (A2X980), HOX16_ORYSJ (Q6YWR4), ICE1_MOUSE  (E9Q286), 
IF61_TRYCC  (Q4E097), ILVD_MYCBO  (P65155), ILVD_MYCTO  (P9WKJ4), 
ILVD_MYCTU  (P9WKJ5), INT13_XENLA (Q6GLY5), INT13_XENTR (Q6DIK0), 
KATIP_XENLA (Q5XK85), KPR5_SCHPO  (P87171), LCKB2_ARATH (O82359), 
LRRK2_HUMAN (Q5S007), LRRK2_MOUSE (Q5S006), MALD1_HUMAN (Q9BSK0), 
MDV1_USTMA  (Q4P8R5), MEND_DECAR  (Q47DK0), MQO_AGRFC   (Q8UH73), 
MSBA_METCA  (Q60AA3), MURD_NOVAD  (Q2G997), NORG_STAA3  (Q2FKF1), 
NORG_STAA8  (Q2G1P1), NORG_STAAB  (Q2YUS3), NORG_STAAC  (Q5HJR1), 
NORG_STAAM  (Q99XA5), NORG_STAAN  (Q7A875), NORR_VIBVU  (Q8D4F9), 
NORR_VIBVY  (Q7MFY9), NUD24_ARATH (P0C026), PCBA_PROMP  (O07295), 
PDXK_TREPA  (O83153), PEPL1_HUMAN (Q8NDH3), PEPL1_MOUSE (Q6NSR8), 
PEPL1_PONAB (Q5R7G6), PGLR1_MAIZE (P26216), PGLR2_JUNAS (Q9FY19), 
PGLR2_MAIZE (P35338), PGLR3_MAIZE (P35339), PGLR4_ARATH (Q949Z1), 
PGLR_ACTDE  (P35336), PGLR_CUPSE  (C0HKB1), PGLR_GOSBA  (Q39766), 
PGLR_GOSHI  (Q39786), PGLR_MALDO  (P48978), PGLR_OENOR  (P24548), 
PGLR_PERAE  (Q02096), PGLR_PRUPE  (P48979), PGLR_SOLLC  (P05117), 
PGLR_TOBAC  (Q05967), PHNW_PSEAB  (Q02JF1), PHNW_PSEAE  (Q9I434), 
PHNW_PSEPF  (Q3K9Y3), POC1B_RAT   (D3ZW91), POLG_HAV88  (Q8V0N6), 
POLG_HAVCF  (Q5Y944), POLG_HAVCR  (P06442), POLG_HAVGB  (Q67825), 
POLG_HAVH2  (A3FMB2), POLG_HAVHA  (Q05794), POLG_HAVHM  (P08617), 
POLG_HAVJ8  (A5LGW7), POLG_HAVLA  (P06441), POLG_HAVMB  (P13901), 
POLG_HAVNO  (Q9DWR1), POLG_HAVS2  (P14553), POLG_HAVSC  (P31788), 
POLN_EOPV   (Q6UP17), PP16A_HUMAN (Q96I34), PP16A_MOUSE (Q923M0), 
PPE14_MYCTO (P9WI32), PPE14_MYCTU (P9WI33), PREU1_PREIS (P9WET8), 
PRO1_CAEBR  (A8WSU9), PRO1_CAEEL  (Q22006), PROF_TRYBB  (Q26734), 
PRPD1_CORGL (Q8NSH9), PULA_THEMA  (O33840), PYRE_COXBU  (Q45918), 
PYRE_ENTFA  (P0DH75), PYRE_ENTFO  (F2MMN7), PYRE_FUSNN  (P58856), 
PYRE_HALH5  (Q9K9W3), PYRE_LACJO  (Q74J27), PYRE_LACPL  (P77889), 
PYRE_LISIN  (Q92AH7), PYRE_LISMF  (Q71YI5), PYRE_LISMO  (Q8Y668), 
PYRE_MALP2  (Q8EUY4), PYRE_OCEIH  (Q8ER35), PYRE_STAAC  (Q5HGM7), 
PYRE_STAAM  (P65916), PYRE_STAAN  (P99144), PYRE_STAAR  (Q6GHN0), 
PYRE_STAAS  (Q6GA08), PYRE_STAAW  (Q8NX25), PYRE_STAEQ  (Q5HPY6), 
PYRE_STAES  (Q8CSW7), PYRE_STAHJ  (Q4L5Q7), PYRE_STAS1  (Q49WY6), 
QRT2_ARATH  (Q9SFB7), RAV1_SCHPO  (Q9Y817), RETST_HUMAN (Q6NUM9), 
RH13_ARATH  (Q93Y39), RIBA_PECAS  (Q6D5U5), RIBA_SALCH  (Q57NU9), 
RIBA_SALPA  (Q5PCY8), RIBA_SALTI  (P66031), RIBA_SALTY  (P66030), 
RIBA_YERPE  (Q8ZEF0), RIBA_YERPS  (Q66AI6), RL25_BORBR  (Q7WNY3), 
RL25_BORPA  (Q7W180), RL25_BORPE  (Q7VUH2), RL6_MYCS5   (Q4A5D6), 
RLMG_PSEE4  (Q1I4K4), RLMG_PSEPG  (B0KHQ8), RLMG_PSEPW  (B1J2W7), 
RNE_NOSS1   (Q8YP69), RS8_FRAAA   (Q0RRQ7), RTBDN_CANLF (Q4TUC0), 
SADH_MYCTO  (P9WGP8), SADH_MYCTU  (P9WGP9), SALK6_KALTU (W8P8Q3), 
SHBG_CROCR  (A0EQL2), SL11_ORYSI  (A2ZLU6), SL11_ORYSJ  (Q0IMG9), 
SYE_LEPBA   (B0SCM4), SYE_LEPBP   (B0SKQ2), T38B2_CAEEL (Q9NA73), 
TAF2_YEAST  (P23255), TAF5_YEAST  (P38129), TAZB_ASPTN  (Q0CS88), 
TRM82_VANPO (A7TEN6), TRPG_THEKO  (Q9YGB2), TSAD_ACET2  (A3DJ13), 
TSAD_CALS4  (Q8RC98), TUAE_BACSU  (O32270), UBR2_HUMAN  (Q8IWV8), 
UBR2_MOUSE  (Q6WKZ8), UGPA3_ARATH (F4IY62), USB1_DANRE  (Q6DEF6), 
VPC51_MYCTU (L0T5V6), WDR12_DICDI (Q54W52), WDR6_SCHPO  (Q9USZ0), 
Y1082_HAEIN (P45026), Y1534_ARATH (C0LGG7), Y2599_MYCTO (P9WL68), 
Y2599_MYCTU (P9WL69), Y5258_ARATH (Q9FK81), YTM1_PICGU  (A5DL92), 
ZD23B_DANRE (F1QX91)
» more

PDB
[Detailed view]
40 PDB

1A12; 1I2M; 3MVD; 3OF7; 4D4O; 4D4P; 4D4Q; 4D9S; 4DNU; 4DNV; 4DNW; 4IGL; 4JHN; 4JHP; 4NAA; 4NBM; 4NC4; 4O2W; 4QAM; 4X33; 5GWN; 5HQ2; 5KIS; 5T94; 5TBK; 5XGS; 6DD7; 6XZL; 6XZM; 6XZN; 7Q40; 7Q41; 7Q42; 7Q43; 7Q44; 7Q45; 7Q46; 7VGG; 8GQE; 8UX1
» more