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PROSITE entry PS00659


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General information about the entry

Entry name [info] GLYCOSYL_HYDROL_F5
Accession [info] PS00659
Entry type [info] PATTERN
Date [info] 01-JUN-1992 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00565

Name and characterization of the entry

Description [info] Glycosyl hydrolases family 5 signature.
Pattern [info]
[LIV]-[LIVMFYWGA](2)-[DNEQG]-[LIVMGST]-{SENR}-N-E-[PV]-[RHDNSTLIVFY].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 190 in 190 different sequences
Number of true positive hits 85 in 85 different sequences
Number of 'unknown' hits 0
Number of false positive hits 105 in 105 different sequences
Number of false negative sequences 73
Number of 'partial' sequences 5
Precision (true positives / (true positives + false positives)) 44.74 %
Recall (true positives / (true positives + false negatives)) 53.80 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site(?) at position 7
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
85 sequences

CELDZ_THESZ (A0A0U4EBH5), CELE_ACET2  (P10477), EG5A_PHACH  (Q66NB7), 
EGCR1_ASPFM (H1AE13), EGCSE_CYANO (Q9GV16), EGCSE_HYDVU (Q6L6S1), 
EGH1_YEAST  (P40566), EXG1_CANAL  (P29717), EXG1_SCHPO  (Q9URU6), 
EXG1_WICAO  (O93939), EXG1_YEAST  (P23776), EXG2_CANAL  (Q5AIA1), 
EXG2_WICAO  (O93983), EXG2_YEAST  (P52911), EXG3_SCHPO  (O74799), 
EXG_CANOL   (Q8NKF9), EXG_KLULA   (Q12628), EXG_LACK1   (Q875R9), 
EXG_PICAN   (Q12626), EXG_SACU7   (Q876J3), EXG_SCHOC   (Q12700), 
EXG_YARLI   (Q12725), GUN1_ACIC1  (P54583), GUN1_BACIU  (P07983), 
GUN1_BUTFI  (P20847), GUN1_EVAC2  (P06566), GUN1_RUMAL  (P16216), 
GUN1_SAIFL  (Q04469), GUN2_BACSU  (P10475), GUN2_EVAC2  (P06565), 
GUN2_HYPJE  (P07982), GUN2_HYPJR  (A0A024SH20), GUN3_BACIU  (P23549), 
GUN3_EVAC2  (P19570), GUN3_FIBSS  (P14250), GUN4_RUMAL  (Q07940), 
GUN5_MICS2  (A0A8A1G1R1), GUN5_SALAG  (O85465), GUN5_THEFU  (Q01786), 
GUNA_BUTFI  (P22541), GUNA_CLOLO  (P54937), GUNA_PAEBA  (O08342), 
GUNA_RUMAL  (P23660), GUNA_RUMCH  (P17901), GUNA_RUMFL  (P16169), 
GUNA_STRLI  (P27035), GUNA_XANCP  (P19487), GUNB_ACET2  (P04956), 
GUNB_CALSA  (P10474), GUNB_CLOC7  (P28621), GUNB_NEOPA  (Q12647), 
GUNB_PAELA  (P23550), GUNB_RUMAL  (P23661), GUNC_ACET2  (A3DJ77), 
GUNC_ACETH  (P0C2S3), GUNC_CELJU  (P27033), GUNC_CLOSF  (P23340), 
GUND_CELFI  (P50400), GUND_CLOC7  (P28623), GUND_RUMCH  (P25472), 
GUNG_ACET2  (Q05332), GUNH_ACET2  (P16218), GUNN_PECAT  (Q59394), 
GUNV_PECCC  (Q47096), GUNW_PECPM  (Q59395), GUNZ_DICD3  (P07103), 
GUN_BACS6   (P19424), GUN_CLOSA   (P15704), GUN_HALA3   (P06564), 
GUN_MAREN   (A0A023VXA2), GUN_PAEPO   (P23548), GUN_RALN1   (P58599), 
GUN_RALSL   (P17974), GUN_ROBSP   (P23044), MAN1_ORYSJ  (Q0JKM9), 
MAN2_ORYSJ  (Q0JJD4), MAN5_CELJU  (B3PF24), MAN7_ORYSJ  (Q2RBB1), 
MAN8_ORYSJ  (Q0IQJ7), MANA_STRLI  (P51529), MANB_CALSA  (P22533), 
SPR1_SACU7  (Q876J2), SPR1_YEAST  (P32603), XYNA_THESA  (P36917), 
XYNX_ACETH  (P38535)
» more

UniProtKB/Swiss-Prot
False negative sequences
73 sequences

6GAL_HYPRU  (Q76FP5), EGCR1_CRYNH (H1AE12), EGCR1_RHIO9 (I1BTD7), 
EGCSE_RHOH1 (A0A3S5YBC7), EXG2_SCHPO  (Q10444), EXGA_ASPCL  (A1CRV0), 
EXGA_ASPFC  (B0XN12), EXGA_ASPFN  (B8N151), EXGA_ASPFU  (Q4WK60), 
EXGA_ASPNC  (A2RAR6), EXGA_ASPOR  (Q7Z9L3), EXGA_ASPTN  (Q0CR35), 
EXGA_EMENI  (Q5B5X8), EXGA_NEOFI  (A1D4Q5), EXGB_ASPFC  (B0XRX9), 
EXGB_ASPFN  (B8NBJ4), EXGB_ASPFU  (Q4X1N4), EXGB_ASPOR  (Q2TZQ9), 
EXGB_ASPTN  (Q0C8Z0), EXGB_EMENI  (Q5B6Q3), EXGB_NEOFI  (A1DGM6), 
EXGD_ASPCL  (A1CTI3), EXGD_ASPFC  (B0Y7W2), EXGD_ASPFN  (B8NNK9), 
EXGD_ASPFU  (Q4WMP0), EXGD_ASPNC  (A2QX52), EXGD_ASPOR  (Q2UMV7), 
EXGD_ASPTN  (Q0CHZ8), EXGD_EMENI  (Q5AVZ7), EXGD_NEOFI  (A1DMX4), 
EXG_BLUGR   (Q96V64), GUN3_HUMIN  (Q12624), MAN1_ARATH  (Q9FZ29), 
MAN1_SOLLC  (O48540), MAN2_ARATH  (Q7Y223), MAN2_SOLLC  (Q9FZ03), 
MAN3_ARATH  (Q9SG94), MAN3_ORYSJ  (Q0DM48), MAN3_SOLLC  (Q9FUQ6), 
MAN4_ARATH  (Q9SG95), MAN4_ORYSJ  (Q10B67), MAN4_SOLLC  (Q8L5J1), 
MAN5_ARATH  (Q9M0H6), MAN5_ORYSJ  (Q5W6G0), MAN5_SOLLC  (Q6YM50), 
MAN6_ARATH  (Q9LZV3), MAN6_ORYSJ  (Q0DCM5), MAN7_ARATH  (Q9FJZ3), 
MAN9_ORYSJ  (Q6Z310), MANA1_ASPTN (Q0CCD0), MANA2_ASPTN (Q0CUG5), 
MANA_ASPAC  (Q00012), MANA_ASPCL  (A1CGC6), MANA_ASPFN  (B8NVK8), 
MANA_ASPNC  (A2QKT4), MANA_ASPOR  (Q2TXJ2), MANA_CRYAT  (B4XC07), 
MANA_EMENI  (Q5B7X2), MANA_MYTED  (Q8WPJ2), MANA_NEOFI  (A1D8Y6), 
MANB_EMENI  (Q5B833), MANC_ASPTN  (Q0C8J3), MANC_EMENI  (Q5AZ53), 
MAND_EMENI  (Q5AVP1), MANF_ASPCL  (A1C8U0), MANF_ASPFC  (B0Y9E7), 
MANF_ASPFN  (B8NIV9), MANF_ASPFU  (Q4WBS1), MANF_ASPOR  (Q2U2I3), 
MANF_EMENI  (Q5AR04), MANF_NEOFI  (A1DBV1), MANP_ARATH  (Q9LW44), 
YBQ6_YEAST  (P38081)
» more

UniProtKB/Swiss-Prot
'Partial' sequences
5 sequences

EXG_PSEMZ   (P85924), GUN1_ACRSP  (P82288), GUNA_GLOTR  (P84194), 
GUNB_GLOTR  (P84196), GUN_SCHCO   (P81190)
» more

UniProtKB/Swiss-Prot
False positive sequences
105 sequences

AGAR_PSEAF  (P13734), AL4A1_DANRE (Q7SY23), AMPA_HELHP  (Q7VGF0), 
ARCA_PSEPK  (Q88P52), ARCA_PSEPU  (P41142), ASP39_ARATH (Q9S9K4), 
ATG4_EREGS  (Q75E61), ATPF1_NITHX (Q1QRI1), C27C1_AQUCT (P0DOX0), 
CDIN1_BOVIN (Q5E9S8), CDIN1_HUMAN (Q9Y2V0), CDIN1_MOUSE (Q3U4G0), 
CDIN1_XENLA (Q6NRW5), CDIN1_XENTR (Q28HL3), CNOT1_CAEEL (Q20937), 
COX1_BACP3  (P16262), CYAA_SCHPO  (P14605), F16A1_PARP8 (B2JEJ7), 
F16A1_PARXL (Q13V64), F16A3_PSET1 (Q3ICJ5), F16PA_ACIAD (Q6F982), 
F16PA_ACISJ (A1W9H6), F16PA_BURL3 (Q39IJ4), F16PA_CAUSK (B0T0R1), 
F16PA_CELJU (B3PGC8), F16PA_HERAR (A4G2P0), F16PA_HERSE (A2RQ29), 
F16PA_IDILO (Q5QVR9), F16PA_PARPJ (B2T699), F16PA_PSYA2 (Q4FUA6), 
F16PA_PSYCK (Q1QDE0), F16PA_RALN1 (Q8XXI7), F16PA_RALPJ (B2U8C4), 
F16PA_SHEAM (A1S351), F16PA_SHEB9 (A9L375), F16PA_SHEDO (Q12JW2), 
F16PA_SHEFN (Q088C3), F16PA_SHEHH (B0TTL6), F16PA_SHELP (A3QAZ7), 
F16PA_SHEON (Q8EAB6), F16PA_SHEPA (A8H0H1), F16PA_SHESA (A0KSW7), 
F16PA_SHESH (A8FRF1), F16PA_SHESM (Q0HMI8), F16PA_SHESR (Q0HRA0), 
F16PA_SHESW (A1RNR2), G6PI_PSEFL  (Q848I4), G6PI_PSEPF  (Q3K6Q4), 
GCSP_BACFN  (Q5LDN2), GCSP_BACFR  (Q64UQ7), HAP2_ARATH  (F4JP36), 
HEPHL_ACRMI (B3EWZ9), ILVB2_BRANA (P14874), JHD1_SCHPO  (O94603), 
K0754_HUMAN (O94854), K0754_MOUSE (Q69ZZ9), LTP_HHV7J   (P52362), 
L_TULV  (Q9YQR5), MACF1_HUMAN (Q9UPN3), MACF1_MOUSE (Q9QXZ0), 
MACF1_RAT   (D3ZHV2), MICA1_DANRE (E7F9T0), MLFA_ASPVC  (A0A319BQC1), 
MYOD_TOXGO  (Q9XYF6), NADL2_HUMAN (Q58DX5), OBSCN_HUMAN (Q5VST9), 
PAC_PRIMG   (Q60136), PAC_RHIVS   (P31956), PNPT1_HUMAN (Q8TCS8), 
PNPT1_MOUSE (Q8K1R3), PNPT1_PONAB (Q5RCW2), PROB_CLOAB  (Q97E63), 
PRUN1_BOVIN (Q5E9Y6), PRUN1_HUMAN (Q86TP1), PRUN1_MOUSE (Q8BIW1), 
PRUN1_RAT   (Q6AYG3), PSA_NAKMY   (C8XAQ3), PTCD3_DANRE (Q32LU7), 
PURL_SACS2  (Q9UX24), PXPA_BACSU  (P42963), PXPA_OCEIH  (Q8EN13), 
R213A_DANRE (A0A0R4IBK5), RECR_AZOC5  (A8IGX4), RFT1_CANGA  (Q6FPE8), 
RL25_RUEPO  (Q5LV90), RNH2_THEPD  (A1RYM0), RPPH_BORBR  (Q7WFP0), 
RPPH_BORPA  (Q7W482), RPPH_BORPE  (Q7VTZ7), RPPH_NITMU  (Q2YBW4), 
RUVC_THIDA  (Q3SGT0), SC15A_ARATH (Q9LXX6), SDK2_MOUSE  (Q6V4S5), 
SP100_MUSCR (O35893), SYFB_PROMP  (Q7V1J8), TAF14_ARATH (F4IPK2), 
TM1R_SOLLC  (A7M6E7), TM1S_SOLLC  (A7M6E8), Y1530_RUBXD (Q1AVT6), 
Y2148_CALS8 (A4XLE5), Y526_SYNWW  (Q0AZJ4), Y5392_ARATH (Q9FID6), 
YB0G_SCHPO  (P87157), YBX7_SCHPO  (Q10201), YL786_MIMIV (Q5UPR9)
» more

PDB
[Detailed view]
55 PDB

1A3H; 1CEC; 1CZ1; 1E5J; 1ECE; 1EDG; 1EGZ; 1EQC; 1EQP; 1G01; 1G0C; 1H11; 1H2J; 1H4P; 1H5V; 1HF6; 1OCQ; 1QHZ; 1QI0; 1QI2; 1VRX; 1W3K; 1W3L; 2A3H; 2CKR; 2CKS; 2PB1; 2PBO; 2PC8; 2PF0; 2V38; 3A3H; 3N9K; 3NDY; 3NDZ; 3O6A; 3PZT; 3PZU; 3PZV; 3QR3; 4A3H; 4IM4; 4M80; 4M81; 4M82; 4TUF; 4U3A; 4U5I; 4U5K; 5A3H; 5BYW; 5FIP; 6A3H; 7A3H; 8A3H
» more