PROSITE entry PS00659

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS00659
Entry name [info]	GLYCOSYL_HYDROL_F5
Accession [info]	PS00659
Entry type [info]	PATTERN
Date [info]	01-JUN-1992 CREATED; 01-DEC-2004 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00565

Name and characterization of the entry

Description [info]	Glycosyl hydrolases family 5 signature.
Pattern [info]	[LIV]-[LIVMFYWGA](2)-[DNEQG]-[LIVMGST]-{SENR}-N-E-[PV]-[RHDNSTLIVFY].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	190 in 190 different sequences
Number of true positive hits	85 in 85 different sequences
Number of 'unknown' hits	0
Number of false positive hits	105 in 105 different sequences
Number of false negative sequences	73
Number of 'partial' sequences	5

Precision (true positives / (true positives + false positives))	44.74 %
Recall (true positives / (true positives + false negatives))	53.80 %

Comments [info]

Taxonomic range [info]	Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Site [info]	active_site(?) at position 7
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	85 sequences CELDZ_THESZ (A0A0U4EBH5), CELE_ACET2 (P10477), EG5A_PHACH (Q66NB7), EGCR1_ASPFM (H1AE13), EGCSE_CYANO (Q9GV16), EGCSE_HYDVU (Q6L6S1), EGH1_YEAST (P40566), EXG1_CANAL (P29717), EXG1_SCHPO (Q9URU6), EXG1_WICAO (O93939), EXG1_YEAST (P23776), EXG2_CANAL (Q5AIA1), EXG2_WICAO (O93983), EXG2_YEAST (P52911), EXG3_SCHPO (O74799), EXG_CANOL (Q8NKF9), EXG_KLULA (Q12628), EXG_LACK1 (Q875R9), EXG_PICAN (Q12626), EXG_SACU7 (Q876J3), EXG_SCHOC (Q12700), EXG_YARLI (Q12725), GUN1_ACIC1 (P54583), GUN1_BACIU (P07983), GUN1_BUTFI (P20847), GUN1_EVAC2 (P06566), GUN1_RUMAL (P16216), GUN1_SAIFL (Q04469), GUN2_BACSU (P10475), GUN2_EVAC2 (P06565), GUN2_HYPJE (P07982), GUN2_HYPJR (A0A024SH20), GUN3_BACIU (P23549), GUN3_EVAC2 (P19570), GUN3_FIBSS (P14250), GUN4_RUMAL (Q07940), GUN5_MICS2 (A0A8A1G1R1), GUN5_SALAG (O85465), GUN5_THEFU (Q01786), GUNA_BUTFI (P22541), GUNA_CLOLO (P54937), GUNA_PAEBA (O08342), GUNA_RUMAL (P23660), GUNA_RUMCH (P17901), GUNA_RUMFL (P16169), GUNA_STRLI (P27035), GUNA_XANCP (P19487), GUNB_ACET2 (P04956), GUNB_CALSA (P10474), GUNB_CLOC7 (P28621), GUNB_NEOPA (Q12647), GUNB_PAELA (P23550), GUNB_RUMAL (P23661), GUNC_ACET2 (A3DJ77), GUNC_ACETH (P0C2S3), GUNC_CELJU (P27033), GUNC_CLOSF (P23340), GUND_CELFI (P50400), GUND_CLOC7 (P28623), GUND_RUMCH (P25472), GUNG_ACET2 (Q05332), GUNH_ACET2 (P16218), GUNN_PECAT (Q59394), GUNV_PECCC (Q47096), GUNW_PECPM (Q59395), GUNZ_DICD3 (P07103), GUN_BACS6 (P19424), GUN_CLOSA (P15704), GUN_HALA3 (P06564), GUN_MAREN (A0A023VXA2), GUN_PAEPO (P23548), GUN_RALN1 (P58599), GUN_RALSL (P17974), GUN_ROBSP (P23044), MAN1_ORYSJ (Q0JKM9), MAN2_ORYSJ (Q0JJD4), MAN5_CELJU (B3PF24), MAN7_ORYSJ (Q2RBB1), MAN8_ORYSJ (Q0IQJ7), MANA_STRLI (P51529), MANB_CALSA (P22533), SPR1_SACU7 (Q876J2), SPR1_YEAST (P32603), XYNA_THESA (P36917), XYNX_ACETH (P38535) » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	73 sequences 6GAL_HYPRU (Q76FP5), EGCR1_CRYNH (H1AE12), EGCR1_RHIO9 (I1BTD7), EGCSE_RHOH1 (A0A3S5YBC7), EXG2_SCHPO (Q10444), EXGA_ASPCL (A1CRV0), EXGA_ASPFC (B0XN12), EXGA_ASPFN (B8N151), EXGA_ASPFU (Q4WK60), EXGA_ASPNC (A2RAR6), EXGA_ASPOR (Q7Z9L3), EXGA_ASPTN (Q0CR35), EXGA_EMENI (Q5B5X8), EXGA_NEOFI (A1D4Q5), EXGB_ASPFC (B0XRX9), EXGB_ASPFN (B8NBJ4), EXGB_ASPFU (Q4X1N4), EXGB_ASPOR (Q2TZQ9), EXGB_ASPTN (Q0C8Z0), EXGB_EMENI (Q5B6Q3), EXGB_NEOFI (A1DGM6), EXGD_ASPCL (A1CTI3), EXGD_ASPFC (B0Y7W2), EXGD_ASPFN (B8NNK9), EXGD_ASPFU (Q4WMP0), EXGD_ASPNC (A2QX52), EXGD_ASPOR (Q2UMV7), EXGD_ASPTN (Q0CHZ8), EXGD_EMENI (Q5AVZ7), EXGD_NEOFI (A1DMX4), EXG_BLUGR (Q96V64), GUN3_HUMIN (Q12624), MAN1_ARATH (Q9FZ29), MAN1_SOLLC (O48540), MAN2_ARATH (Q7Y223), MAN2_SOLLC (Q9FZ03), MAN3_ARATH (Q9SG94), MAN3_ORYSJ (Q0DM48), MAN3_SOLLC (Q9FUQ6), MAN4_ARATH (Q9SG95), MAN4_ORYSJ (Q10B67), MAN4_SOLLC (Q8L5J1), MAN5_ARATH (Q9M0H6), MAN5_ORYSJ (Q5W6G0), MAN5_SOLLC (Q6YM50), MAN6_ARATH (Q9LZV3), MAN6_ORYSJ (Q0DCM5), MAN7_ARATH (Q9FJZ3), MAN9_ORYSJ (Q6Z310), MANA1_ASPTN (Q0CCD0), MANA2_ASPTN (Q0CUG5), MANA_ASPAC (Q00012), MANA_ASPCL (A1CGC6), MANA_ASPFN (B8NVK8), MANA_ASPNC (A2QKT4), MANA_ASPOR (Q2TXJ2), MANA_CRYAT (B4XC07), MANA_EMENI (Q5B7X2), MANA_MYTED (Q8WPJ2), MANA_NEOFI (A1D8Y6), MANB_EMENI (Q5B833), MANC_ASPTN (Q0C8J3), MANC_EMENI (Q5AZ53), MAND_EMENI (Q5AVP1), MANF_ASPCL (A1C8U0), MANF_ASPFC (B0Y9E7), MANF_ASPFN (B8NIV9), MANF_ASPFU (Q4WBS1), MANF_ASPOR (Q2U2I3), MANF_EMENI (Q5AR04), MANF_NEOFI (A1DBV1), MANP_ARATH (Q9LW44), YBQ6_YEAST (P38081) » more
UniProtKB/Swiss-Prot 'Partial' sequences	5 sequences EXG_PSEMZ (P85924), GUN1_ACRSP (P82288), GUNA_GLOTR (P84194), GUNB_GLOTR (P84196), GUN_SCHCO (P81190) » more
UniProtKB/Swiss-Prot False positive sequences	105 sequences AGAR_PSEAF (P13734), AL4A1_DANRE (Q7SY23), AMPA_HELHP (Q7VGF0), ARCA_PSEPK (Q88P52), ARCA_PSEPU (P41142), ASP39_ARATH (Q9S9K4), ATG4_EREGS (Q75E61), ATPF1_NITHX (Q1QRI1), C27C1_AQUCT (P0DOX0), CDIN1_BOVIN (Q5E9S8), CDIN1_HUMAN (Q9Y2V0), CDIN1_MOUSE (Q3U4G0), CDIN1_XENLA (Q6NRW5), CDIN1_XENTR (Q28HL3), CNOT1_CAEEL (Q20937), COX1_BACP3 (P16262), CYAA_SCHPO (P14605), F16A1_PARP8 (B2JEJ7), F16A1_PARXL (Q13V64), F16A3_PSET1 (Q3ICJ5), F16PA_ACIAD (Q6F982), F16PA_ACISJ (A1W9H6), F16PA_BURL3 (Q39IJ4), F16PA_CAUSK (B0T0R1), F16PA_CELJU (B3PGC8), F16PA_HERAR (A4G2P0), F16PA_HERSE (A2RQ29), F16PA_IDILO (Q5QVR9), F16PA_PARPJ (B2T699), F16PA_PSYA2 (Q4FUA6), F16PA_PSYCK (Q1QDE0), F16PA_RALN1 (Q8XXI7), F16PA_RALPJ (B2U8C4), F16PA_SHEAM (A1S351), F16PA_SHEB9 (A9L375), F16PA_SHEDO (Q12JW2), F16PA_SHEFN (Q088C3), F16PA_SHEHH (B0TTL6), F16PA_SHELP (A3QAZ7), F16PA_SHEON (Q8EAB6), F16PA_SHEPA (A8H0H1), F16PA_SHESA (A0KSW7), F16PA_SHESH (A8FRF1), F16PA_SHESM (Q0HMI8), F16PA_SHESR (Q0HRA0), F16PA_SHESW (A1RNR2), G6PI_PSEFL (Q848I4), G6PI_PSEPF (Q3K6Q4), GCSP_BACFN (Q5LDN2), GCSP_BACFR (Q64UQ7), HAP2_ARATH (F4JP36), HEPHL_ACRMI (B3EWZ9), ILVB2_BRANA (P14874), JHD1_SCHPO (O94603), K0754_HUMAN (O94854), K0754_MOUSE (Q69ZZ9), LTP_HHV7J (P52362), L_TULV (Q9YQR5), MACF1_HUMAN (Q9UPN3), MACF1_MOUSE (Q9QXZ0), MACF1_RAT (D3ZHV2), MICA1_DANRE (E7F9T0), MLFA_ASPVC (A0A319BQC1), MYOD_TOXGO (Q9XYF6), NADL2_HUMAN (Q58DX5), OBSCN_HUMAN (Q5VST9), PAC_PRIMG (Q60136), PAC_RHIVS (P31956), PNPT1_HUMAN (Q8TCS8), PNPT1_MOUSE (Q8K1R3), PNPT1_PONAB (Q5RCW2), PROB_CLOAB (Q97E63), PRUN1_BOVIN (Q5E9Y6), PRUN1_HUMAN (Q86TP1), PRUN1_MOUSE (Q8BIW1), PRUN1_RAT (Q6AYG3), PSA_NAKMY (C8XAQ3), PTCD3_DANRE (Q32LU7), PURL_SACS2 (Q9UX24), PXPA_BACSU (P42963), PXPA_OCEIH (Q8EN13), R213A_DANRE (A0A0R4IBK5), RECR_AZOC5 (A8IGX4), RFT1_CANGA (Q6FPE8), RL25_RUEPO (Q5LV90), RNH2_THEPD (A1RYM0), RPPH_BORBR (Q7WFP0), RPPH_BORPA (Q7W482), RPPH_BORPE (Q7VTZ7), RPPH_NITMU (Q2YBW4), RUVC_THIDA (Q3SGT0), SC15A_ARATH (Q9LXX6), SDK2_MOUSE (Q6V4S5), SP100_MUSCR (O35893), SYFB_PROMP (Q7V1J8), TAF14_ARATH (F4IPK2), TM1R_SOLLC (A7M6E7), TM1S_SOLLC (A7M6E8), Y1530_RUBXD (Q1AVT6), Y2148_CALS8 (A4XLE5), Y526_SYNWW (Q0AZJ4), Y5392_ARATH (Q9FID6), YB0G_SCHPO (P87157), YBX7_SCHPO (Q10201), YL786_MIMIV (Q5UPR9) » more
PDB [Detailed view]	55 PDB 1A3H; 1CEC; 1CZ1; 1E5J; 1ECE; 1EDG; 1EGZ; 1EQC; 1EQP; 1G01; 1G0C; 1H11; 1H2J; 1H4P; 1H5V; 1HF6; 1OCQ; 1QHZ; 1QI0; 1QI2; 1VRX; 1W3K; 1W3L; 2A3H; 2CKR; 2CKS; 2PB1; 2PBO; 2PC8; 2PF0; 2V38; 3A3H; 3N9K; 3NDY; 3NDZ; 3O6A; 3PZT; 3PZU; 3PZV; 3QR3; 4A3H; 4IM4; 4M80; 4M81; 4M82; 4TUF; 4U3A; 4U5I; 4U5K; 5A3H; 5BYW; 5FIP; 6A3H; 7A3H; 8A3H » more