PROSITE logo

PROSITE entry PS00663


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
PURL: https://purl.expasy.org/prosite/signature/PS00663

Direct ScanProsite submission
General information about the entry

Entry name [info] VINCULIN_1
Accession [info] PS00663
Entry type [info] PATTERN
Date [info] 01-JUN-1992 CREATED;
01-JUN-1994 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00568

Name and characterization of the entry

Description [info] Vinculin family talin-binding region signature.
Pattern [info] 
[KR]-x-[LIVMF]-x(3)-[LIVMA]-x(2)-[LIVM]-x(6)-R-Q-Q-E-L.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 18 in 18 different sequences
Number of true positive hits 18 in 18 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 6
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 75.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 18 sequences 

CTNA1_BOVIN (Q3MHM6), CTNA1_DANRE (Q9PVF8), CTNA1_HUMAN (P35221), 

CTNA1_MOUSE (P26231), CTNA1_RABIT (Q59I72), CTNA2_CHICK (P30997), 
CTNA2_HUMAN (P26232), CTNA2_MOUSE (Q61301), CTNA2_PONAB (Q5R416), 
CTNA2_XENLA (Q6GLP0), CTNA2_XENTR (A4IGI7), CTNA_DROME  (P35220), 
VINC_CAEEL  (P19826), VINC_CHICK  (P12003), VINC_HUMAN  (P18206), 
VINC_MOUSE  (Q64727), VINC_PIG(P26234), VINC_RAT(P85972)
» more

UniProtKB/Swiss-Prot
False negative sequences		 6 sequences 

CTNA2_DANRE (B7ZC77), CTNA3_HUMAN (Q9UI47), CTNA3_MOUSE (Q65CL1), 

VINC_BRUMA  (Q17162), VINC_DICDI  (Q54MH2), VINC_DROME  (O46037)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

VINC_XENLA  (Q04615)


				
	

	

		PDB
[Detailed view]		
		
			44 PDB
			


			pdb_00001dov; pdb_00001dow; pdb_00001rkc; pdb_00001rke; pdb_00001st6; pdb_00001syq; pdb_00001t01; pdb_00001tr2; pdb_00001u6h; pdb_00001xwj; pdb_00001ydi; pdb_00001zvz; 
			
				pdb_00001zw2; pdb_00001zw3; pdb_00002gdc; pdb_00002gww; pdb_00002hsq; pdb_00002ibf; pdb_00003rf3; pdb_00003s90; pdb_00003tj5; pdb_00003tj6; pdb_00003zdl; pdb_00004dj9; 
				pdb_00004e17; pdb_00004e18; pdb_00004ehp; pdb_00004igg; pdb_00004k1n; pdb_00004ons; pdb_00004p9t; pdb_00005y04; pdb_00006fq4; pdb_00006fuy; pdb_00006nr7; pdb_00006o3e; 
				pdb_00006upv; pdb_00006upw; pdb_00007ktt; pdb_00007ktu; pdb_00007ktv; pdb_00007ktw; pdb_00007utj; pdb_00009dva
			
			

			» more