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PROSITE entry PS00663


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00663
Entry name [info] VINCULIN_1
Accession [info] PS00663
Entry type [info] PATTERN
Date [info] 01-JUN-1992 CREATED;
01-JUN-1994 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00568

Name and characterization of the entry

Description [info] Vinculin family talin-binding region signature.
Pattern [info] 
[KR]-x-[LIVMF]-x(3)-[LIVMA]-x(2)-[LIVM]-x(6)-R-Q-Q-E-L.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 18 in 18 different sequences
Number of true positive hits 18 in 18 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 6
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 75.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 18 sequences 

CTNA1_BOVIN (Q3MHM6), CTNA1_DANRE (Q9PVF8), CTNA1_HUMAN (P35221), 

CTNA1_MOUSE (P26231), CTNA1_RABIT (Q59I72), CTNA2_CHICK (P30997), 
CTNA2_HUMAN (P26232), CTNA2_MOUSE (Q61301), CTNA2_PONAB (Q5R416), 
CTNA2_XENLA (Q6GLP0), CTNA2_XENTR (A4IGI7), CTNA_DROME  (P35220), 
VINC_CAEEL  (P19826), VINC_CHICK  (P12003), VINC_HUMAN  (P18206), 
VINC_MOUSE  (Q64727), VINC_PIG(P26234), VINC_RAT(P85972)
» more

UniProtKB/Swiss-Prot
False negative sequences		 6 sequences 

CTNA2_DANRE (B7ZC77), CTNA3_HUMAN (Q9UI47), CTNA3_MOUSE (Q65CL1), 

VINC_BRUMA  (Q17162), VINC_DICDI  (Q54MH2), VINC_DROME  (O46037)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

VINC_XENLA  (Q04615)


				
	

	

		PDB
[Detailed view]		
		
			44 PDB
			


			1DOV; 1DOW; 1RKC; 1RKE; 1ST6; 1SYQ; 1T01; 1TR2; 1U6H; 1XWJ; 1YDI; 1ZVZ; 
			
				1ZW2; 1ZW3; 2GDC; 2GWW; 2HSQ; 2IBF; 3RF3; 3S90; 3TJ5; 3TJ6; 3ZDL; 4DJ9; 
				4E17; 4E18; 4EHP; 4IGG; 4K1N; 4ONS; 4P9T; 5Y04; 6FQ4; 6FUY; 6NR7; 6O3E; 
				6UPV; 6UPW; 7KTT; 7KTU; 7KTV; 7KTW; 7UTJ; 9DVA
			
			

			» more