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PROSITE entry PS00670


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00670
Entry name [info] D_2_HYDROXYACID_DH_2
Accession [info] PS00670
Entry type [info] PATTERN
Date [info] 01-JUN-1992 CREATED;
01-JUL-1998 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00063

Name and characterization of the entry

Description [info] D-isomer specific 2-hydroxyacid dehydrogenases signature 2.
Pattern [info] 
[LIVMFYWA]-[LIVFYWC]-x(2)-[SAC]-[DNQHR]-[IVFA]-[LIVF]-x-[LIVF]-[HNI]-x-
P-x(4)-[STN]-x(2)-[LIVMF]-x-[GSDN].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 138 in 138 different sequences
Number of true positive hits 138 in 138 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 263
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 34.41 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 138 sequences 

DDH1_SCHPO  (Q9P7P8), DDH2_SCHPO  (Q9P7Q1), DDH_HAEIN   (P44501),
» more

UniProtKB/Swiss-Prot
False negative sequences		 263 sequences 

2KGR_GLUOX  (Q5FTU6), CTBP1_CAEEL (Q20595), CTBP1_HUMAN (Q13363),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

YMP5_STRCH  (P43169)


				
	

	

		PDB
[Detailed view]		
		
			57 PDB
			


			1DXY; 1GDH; 1J49; 1J4A; 1PSD; 1SC6; 1YBA; 1YGY; 2DLD; 2FSS; 2G76; 2GO1; 
			
			

			» more