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PROSITE entry PS00675


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General information about the entry

Entry name [info] SIGMA54_INTERACT_1
Accession [info] PS00675
Entry type [info] PATTERN
Date [info] 01-JUN-1992 CREATED;
01-NOV-1995 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00579

Name and characterization of the entry

Description [info] Sigma-54 interaction domain ATP-binding region A signature.
Pattern [info] 
[LIVMFY](3)-x-G-[DEQ]-[STE]-G-[STAV]-G-K-x(2)-[LIVMFY].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 393 in 393 different sequences
Number of true positive hits 137 in 137 different sequences
Number of 'unknown' hits 0
Number of false positive hits 256 in 256 different sequences
Number of false negative sequences 27
Number of 'partial' sequences 3
Precision (true positives / (true positives + false positives)) 34.86 %
Recall (true positives / (true positives + false negatives)) 83.54 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 137 sequences 

ACOR_CUPNH  (P28614), ALGB_PSEAE  (P23747), ALGB_PSEPK  (Q88RJ6), 

ALGB_PSESM  (Q88AQ2), ANFA_AZOVI  (P12626), ATOC_ECOLI  (Q06065), 
CHS5_PYRGI  (O93809), CHS6_PYRO7  (G4N0X4), DCTD_PSEAE  (Q9HU19), 
DCTD_RHILE  (P10046), DCTD_RHIME  (P13632), DHAR_CITFR  (P45512), 
DHAR_ECOLI  (P76016), FHLA_ECOLI  (P19323), FHLA_SALTS  (E1WAA4), 
FHLA_SALTY  (P0CL46), FLBD_CAUVC  (P17899), FLEQ_PSEAE  (G3XCV0), 
FLER_PSEAE  (Q9I4N3), FLGR_HELPY  (O25408), GLRR_ECOLI  (P0AFU4), 
HOXA_BRADU  (P31908), HOXA_CUPNH  (P29267), HRPR_PSESY  (P37930), 
HRPS_PSESH  (P26316), HYFR_ECOLI  (P71229), LIHY_GEOSE  (O85057), 
LUXO_VIBC3  (O87455), MDN1_ARATH  (A0A1P8AUY4), MDN1_DICDI  (Q869L3), 
MOPR_ACIGI  (Q43965), NIFA_AZOBR  (P30667), NIFA_AZOC5  (P09133), 
NIFA_AZOLI  (P54929), NIFA_AZOVI  (P09570), NIFA_BRADU  (P05407), 
NIFA_ENTAG  (P54930), NIFA_HERSE  (P27713), NIFA_KLEOX  (P56266), 
NIFA_KLEPN  (P03027), NIFA_RHIEC  (P54931), NIFA_RHILE  (P09828), 
NIFA_RHILT  (P24426), NIFA_RHIME  (P03028), NIFA_RHOCA  (P0CY94), 
NIFA_RHOCB  (D5ARW9), NIFA_SINFN  (Q53206), NORR1_CUPNH (Q9K4V0), 
NORR2_CUPNH (Q9K4U8), NORR_AERHH  (A0KEJ0), NORR_AERS4  (A4STH5), 
NORR_ALIF1  (Q5E3W8), NORR_CITK8  (A8ANR6), NORR_ECO24  (A7ZQD8), 
NORR_ECO27  (B7UHC1), NORR_ECO45  (B7MKH8), NORR_ECO55  (B7LEC0), 
NORR_ECO57  (Q8X854), NORR_ECO5E  (B5Z370), NORR_ECO7I  (B7NSI9), 
NORR_ECO81  (B7MZ04), NORR_ECO8A  (B7M9E6), NORR_ECOBW  (C4ZYV4), 
NORR_ECODH  (B1XCN6), NORR_ECOHS  (A8A3I6), NORR_ECOK1  (A1AEP9), 
NORR_ECOL5  (Q0TEH1), NORR_ECOL6  (Q8FEN6), NORR_ECOLC  (B1IUX0), 
NORR_ECOLI  (P37013), NORR_ECOLU  (B7N6T9), NORR_ECOSE  (B6I695), 
NORR_ECOSM  (B1LQ27), NORR_ECOUT  (Q1R7Z1), NORR_ENT38  (A4WDR5), 
NORR_ESCF3  (B7LW25), NORR_KLEP3  (B5XVA2), NORR_KLEP7  (A6TCX4), 
NORR_PECAS  (Q6D8R9), NORR_SALA4  (B5F363), NORR_SALAR  (A9MFX7), 
NORR_SALCH  (Q57KT4), NORR_SALDC  (B5FSZ0), NORR_SALEP  (B5QV88), 
NORR_SALG2  (B5RDG4), NORR_SALHS  (B4TF23), NORR_SALNS  (B4T3B0), 
NORR_SALPA  (Q5PF20), NORR_SALPB  (A9N0D7), NORR_SALPC  (C0PWN2), 
NORR_SALSV  (B4TT16), NORR_SALTI  (Q8Z4C6), NORR_SALTY  (Q8ZMJ8), 
NORR_SERP5  (A8GG93), NORR_SHIBS  (Q31X73), NORR_SHIDS  (Q32CL9), 
NORR_SHIF8  (Q0T1D4), NORR_SHIFL  (P59402), NORR_SHISS  (Q3YYF5), 
NORR_VIBVU  (Q8D4F9), NORR_VIBVY  (Q7MFY9), NTRC_AZOC5  (Q04848), 
NTRC_BRASR  (P10576), NTRC_ECO57  (P0AFB9), NTRC_ECOLI  (P0AFB8), 
NTRC_KLEPN  (P03029), NTRC_PROHU  (P28787), NTRC_RHIME  (P10577), 
NTRC_RHOCB  (P09432), NTRC_SALTY  (P41789), PILR_PSEAE  (Q00934), 
QSEF_ECO57  (P0AFU5), RAB5B_PLAF7 (Q76NM7), RAC2A_ARATH (O49841), 
RAC2B_ARATH (Q9SF92), ROCR_BACSU  (P38022), SFNR_PSEPF  (Q3K999), 
SFNR_PSEPU  (Q845S7), SHS1_CANAL  (Q59VX8), STC_CLOBE   (P26047), 
TYRR_ECOLI  (P07604), TYRR_ENTAG  (Q9ZIB7), TYRR_HAEIN  (P44694), 
TYRR_SALTI  (P0A2D8), TYRR_SALTY  (P0A2D7), UACR_ECOLI  (Q46802), 
VASH_VIBCH  (Q9KN48), VNFA_AZOVI  (P12627), WTSA_PANSE  (P36219), 
XYLR_PSEPU  (P06519), YHYA_PSESN  (Q01265), YQIR_BACSU  (P54529), 
ZRAR_ECO57  (Q8X613), ZRAR_ECOLI  (P14375), ZRAR_KLEOX  (Q9APD9), 
ZRAR_SALTI  (Q8Z333), ZRAR_SALTY  (P25852)
» more

UniProtKB/Swiss-Prot
False negative sequences		 27 sequences 

ACOR_BACSU  (O31551), DGAR_SALT1  (D0ZLR9), HRPS_PSESY  (P37931), 

HUPR_RHOCA  (P26408), LEVR_BACSU  (P23914), LUXO_VIBC1  (A7MVC2), 
LUXO_VIBCH  (Q9KT84), LUXO_VIBHA  (P0C5S5), LUXO_VIBPA  (Q87MX7), 
LUXO_VIBVU  (Q8CWJ5), MIMR_MYCGD  (G3XGC1), MIMR_MYCS2  (A0QTU7), 
NTRC_AZOBR  (P45671), NTRXL_RICBR (Q1RJS1), NTRXL_RICCN (Q92HC2), 
NTRXL_RICFE (Q4UL27), NTRXL_RICPR (Q9ZCY9), NTRXL_RICTY (Q68WH4), 
NTRX_AZOC5  (Q04849), PGTA_SALTY  (P06184), PRPR_ECOLI  (P77743), 
PRPR_SALTY  (P74839), PSPF_ECOLI  (P37344), RTCR_ECOLI  (P38035), 
TYRR_CITBR  (O54426), Y4PA_SINFN  (P55610), YPLP_BACSU  (P54156)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 3 sequences 

NIFA_AZOCH  (P56269), NTRC_VIBAL  (P19905), YFHA_KLEOX  (P21710)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			256 sequences
			


			
DNAA_TROW8  (Q83NZ5), DNAA_TROWT  (Q83N52), GEM1_KLULA  (Q6CY37), 

			
GEM1_YARLI  (Q6C2J1), GEM1_YEAST  (P39722), HPRK2_OCEIH (Q8EL04), 
HPRK_NITEU  (Q82Y30), HPRK_UREPA  (Q9PR69), ISTB_BACFR  (Q64NF1), 
LIIP1_ARATH (Q9C5J9), LIIP2_ARATH (F4KFD8), MDN1_YEAST  (Q12019), 
PEZT_STRPN  (Q97QZ1), PHNC2_HALWD (Q18H36), PHNC_HALSA  (Q9HNI8), 
PTLH_BORBR  (Q7WDT5), PTLH_BORPA  (Q7W2T7), PTLH_BORPE  (Q7VSX3), 
QKGA_DICDI  (Q8SSS9), RAA1A_ARATH (P28185), RAA1B_ARATH (Q39222), 
RAA1C_ARATH (Q9FK68), RAA1D_ARATH (Q9SN35), RAA1E_ARATH (O49513), 
RAA1F_ARATH (Q9FJH0), RAA1G_ARATH (Q9LK99), RAA1H_ARATH (Q1PEX3), 
RAA1I_ARATH (Q9S810), RAA2A_ARATH (O04486), RAA2B_ARATH (Q9LNW1), 
RAA2C_ARATH (Q96283), RAA2D_ARATH (Q9FIF9), RAB10_CAEEL (Q94148), 
RAB10_CANLF (P24409), RAB10_CHICK (Q5ZIT5), RAB10_DIPOM (P22127), 
RAB10_HUMAN (P61026), RAB10_MOUSE (P61027), RAB10_PONAB (Q5R5U1), 
RAB10_RAT   (P35281), RAB13_BOVIN (Q58DS5), RAB13_CANLF (F1PTE3), 
RAB13_DANRE (Q7T3A4), RAB13_HUMAN (P51153), RAB13_MESAU (Q5KTJ6), 
RAB13_MOUSE (Q9DD03), RAB13_RAT   (P35286), RAB15_BOVIN (Q1RMR4), 
RAB15_HUMAN (P59190), RAB15_MOUSE (Q8K386), RAB15_RAT   (P35289), 
RAB18_BOVIN (Q0IIG8), RAB18_CAEBR (P90726), RAB18_CAEEL (Q8MXS1), 
RAB18_CHICK (Q5ZLG1), RAB18_HUMAN (Q9NP72), RAB18_MOUSE (P35293), 
RAB18_PONAB (Q5R5H5), RAB18_RAT   (Q5EB77), RAB1A_ARATH (O23561), 
RAB1A_CANLF (P62822), RAB1A_DICDI (P34139), RAB1A_HUMAN (P62820), 
RAB1A_LYMST (Q05974), RAB1A_MOUSE (P62821), RAB1A_PIG   (Q52NJ2), 
RAB1A_RAT   (Q6NYB7), RAB1B_ARATH (Q38922), RAB1B_BOVIN (Q2HJH2), 
RAB1B_DICDI (P34140), RAB1B_HUMAN (Q9H0U4), RAB1B_MACFA (Q4R8X3), 
RAB1B_MOUSE (Q9D1G1), RAB1B_PIG   (Q06AU7), RAB1B_PONAB (Q5RE13), 
RAB1B_RAT   (P10536), RAB1C_ARATH (P92963), RAB1C_DICDI (O76173), 
RAB1C_HUMAN (Q92928), RAB1D_DICDI (Q54NU2), RAB1_DIPOM  (P22125), 
RAB1_THEAN  (Q4UB16), RAB1_THEPA  (Q9TVU5), RAB25_BOVIN (Q58DW6), 
RAB25_CANLF (E2RQ15), RAB25_HUMAN (P57735), RAB25_MOUSE (Q9WTL2), 
RAB25_RABIT (P46629), RAB26_BOVIN (Q29RR0), RAB26_HUMAN (Q9ULW5), 
RAB26_MOUSE (Q504M8), RAB26_RAT   (P51156), RAB2A_CANLF (P61105), 
RAB2A_CHICK (Q90965), RAB2A_DICDI (P36409), RAB2A_HUMAN (P61019), 
RAB2A_MACFA (Q4R4X6), RAB2A_MAIZE (P49103), RAB2A_MOUSE (P53994), 
RAB2A_PONAB (Q5R6B6), RAB2A_RABIT (Q01971), RAB2A_RAT   (P05712), 
RAB2B_HUMAN (Q8WUD1), RAB2B_MAIZE (P49104), RAB2B_MOUSE (P59279), 
RAB2_LYMST  (Q05975), RAB35_HUMAN (Q15286), RAB35_MOUSE (Q6PHN9), 
RAB35_RAT   (Q5U316), RAB37_HUMAN (Q96AX2), RAB37_MOUSE (Q9JKM7), 
RAB7A_BOVIN (Q3T0F5), RAB7A_CANLF (P18067), RAB7A_DICDI (P36411), 
RAB7A_HUMAN (P51149), RAB7A_MOUSE (P51150), RAB7A_PAROT (Q95UJ0), 
RAB7A_PONAB (Q5R9Y4), RAB7A_RABIT (O97572), RAB7A_RAT   (P09527), 
RAB7B_PAROT (Q6DUB4), RAB7_CENCI  (Q40787), RAB7_EPICO  (H9BW96), 
RAB7_GIBZE  (I1RMF2), RAB7_GOSHI  (Q9XER8), RAB7_MESCR  (P93267), 
RAB7_NEUCR  (Q9C2L8), RAB7_PEA(P31022), RAB7_PRUAR  (O24461), 
RAB7_SOYBN  (Q43463), RAB7_VIGAC  (Q41640), RAB8A_BOVIN (A4FV54), 
RAB8A_CANLF (P61007), RAB8A_DICDI (P20790), RAB8A_HUMAN (P61006), 
RAB8A_MACFA (Q4R5P1), RAB8A_MOUSE (P55258), RAB8A_PONAB (Q5R4A3), 
RAB8A_RAT   (P35280), RAB8B_BOVIN (Q2HJI8), RAB8B_DICDI (P20791), 
RAB8B_HUMAN (Q92930), RAB8B_MOUSE (P61028), RAB8B_PONAB (Q5REC9), 
RAB8B_RAT   (P70550), RAB8_DIPOM  (P22128), RABA_DICDI  (P34141), 
RABC1_ARATH (O23657), RABC_DICDI  (P34143), RABF1_ARATH (Q9CB01), 
RABF1_DICDI (Q558I0), RABG1_ARATH (Q948K6), RABG2_ARATH (Q9SJ11), 
RABL3_BOVIN (Q32LJ6), RABL3_CHICK (Q5ZKR4), RABL3_DANRE (Q6TNS7), 
RABL3_HUMAN (Q5HYI8), RABL3_MOUSE (Q9D4V7), RABL3_XENLA (Q6GPS4), 
RABL3_XENTR (A4IHM6), RAD2A_ARATH (P28188), RAD2B_ARATH (Q9FPJ4), 
RAD2C_ARATH (Q9SEH3), RAE1A_ARATH (O24466), RAE1C_ARATH (P28186), 
RAE1D_ARATH (Q9LZD4), RAE1E_ARATH (Q9SF91), RAG3A_ARATH (Q948K8), 
RAG3B_ARATH (O04157), RAG3C_ARATH (Q9LW76), RAG3D_ARATH (Q9C820), 
RAG3E_ARATH (Q9XI98), RAG3F_ARATH (Q9LS94), RB11A_BOVIN (Q2TA29), 
RB11A_CAEEL (O01803), RB11A_CANLF (P62490), RB11A_CHICK (Q5ZJN2), 
RB11A_DICDI (P36412), RB11A_HUMAN (P62491), RB11A_MOUSE (P62492), 
RB11A_PIG   (Q52NJ1), RB11A_PONAB (Q5R9M7), RB11A_RABIT (P62493), 
RB11A_RAT   (P62494), RB11A_TOBAC (Q40523), RB11B_BOVIN (Q3MHP2), 
RB11B_DICDI (Q54KM9), RB11B_DIPOM (P22129), RB11B_HUMAN (Q15907), 
RB11B_MOUSE (P46638), RB11B_RAT   (O35509), RB11B_TOBAC (Q40521), 
RB11C_LOTJA (Q40193), RB11D_LOTJA (Q40194), RB11E_LOTJA (Q40195), 
RB18A_LYMST (Q05976), RB18B_DANRE (Q6DHC1), RB1BV_BETVU (Q39433), 
RB2BV_BETVU (Q39434), REM2_HUMAN  (Q8IYK8), REM2_MOUSE  (Q8VEL9), 
REM2_RAT(Q9WTY2), RIC1_ORYSJ  (P40392), RIC2_ORYSJ  (P40393), 
RLGP2_ORYSJ (Q40723), ROC11_DICDI (Q6XHA5), ROCO4_DICDI (Q6XHB2), 
RSGA_STAAC  (Q9KX08), RSGA_STAAM  (P67681), RSGA_STAAN  (P67682), 
RSGA_STAAR  (Q6GHL4), RSGA_STAAS  (Q6G9Z2), RSGA_STAAW  (P67683), 
RSGA_STAEQ  (Q5HPX0), RSGA_STAES  (Q8CSV8), RSGA_STAHJ  (Q4L5S2), 
RYL1_YARLI  (P41924), SBCC_LACLA  (Q9CFZ0), SEC4_CANAL  (P0CY31), 
SEC4_CANAW  (C4YL11), SEC4_CANAX  (P0CY30), SEC4_CANGA  (O42819), 
SEC4_YEAST  (P07560), SPN1_SCHPO  (O36023), SUNT_BACSU  (P68579), 
SUNT_BPSPB  (P68580), V3_SPTNK(B4YNE3), VIRBB_BRUA2 (Q2YJ82), 
VIRBB_BRUAB (P0C534), VIRBB_BRUME (Q8YDY9), VIRBB_BRUSU (Q8FXK7), 
Y6523_BACAN (Q6F054), Y7407_DICDI (Q54KD0), Y8923_DICDI (Q54FZ8), 
YPT1_NEUCR  (P33723), YPT1_PHYIN  (Q01890), YPT1_SCHPO  (P11620), 
YPT2_SCHPO  (P17609), YPT31_YEAST (P38555), YPT32_YEAST (P51996), 
YPT3_NICPL  (Q01111), YPT71_SCHPO (Q9HDY0), YPT7_EMENI  (C8VQY7), 
YPT7_PYRO7  (G4MYS1), YPT7_SCHPO  (O94655), YPT7_YEAST  (P32939), 
YPTC1_CHLRE (Q39571), YPTC4_CHLRE (Q39570), YPTC5_CHLRE (Q39573), 
YPTC6_CHLRE (Q39572), YPTM2_MAIZE (Q05737), YPTV1_VOLCA (P31584), 
YPTV2_VOLCA (P36861), YPTV3_VOLCA (P36862), YPTV4_VOLCA (P36863), 
YPTV5_VOLCA (P36864)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			11 PDB
			


			1OJL; 5EXP; 5EXS; 5EXT; 5EXX; 6J7E; 6JDI; 6JDL; 7EJW; 8P53; 8PB9