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PROSITE entry PS00689


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00689
Entry name [info] GLYCO_HORMONE_BETA_2
Accession [info] PS00689
Entry type [info] PATTERN
Date [info] 01-JUN-1992 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00234

Name and characterization of the entry

Description [info] Glycoprotein hormones beta chain signature 2.
Pattern [info] 
[PA]-V-A-x(2)-C-x-C-x(2)-C-x(4)-[STDAI]-[DEY]-C-x(6,8)-[PGSTAVMI]-x(2)-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 108 in 108 different sequences
Number of true positive hits 108 in 108 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 3
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 97.30 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 5
Site [info] disulfide at position 7
Site [info] disulfide at position 9
Site [info] disulfide at position 13
Site [info] disulfide at position 17
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 108 sequences 

CGB1_HUMAN  (A6NKQ9), CGB2_HUMAN  (Q6NT52), CGB3_HUMAN  (P0DN86), 

CGB7_HUMAN  (P0DN87), CGHB_AOTNA  (Q3HRV3), CGHB_CALJA  (P51500), 
CGHB_PAPAN  (P07434), FSHB_AILME  (Q8WN19), FSHB_AOTNA  (Q3HRV4), 
FSHB_AQUCT  (Q9PS36), FSHB_BOVIN  (P04837), FSHB_BUBBU  (Q6SV86), 
FSHB_CAPHI  (Q8HY83), FSHB_CAVPO  (Q9JK69), FSHB_CERNI  (Q8HY84), 
FSHB_GORGO  (A1BN60), FSHB_HORSE  (P01226), FSHB_HUMAN  (P01225), 
FSHB_MACFA  (Q6EV79), FSHB_MASCO  (Q6SI68), FSHB_MERUN  (Q6U830), 
FSHB_MONDO  (Q95J82), FSHB_MOUSE  (Q60687), FSHB_PANTA  (Q9BDJ0), 
FSHB_PANTR  (Q2PUH2), FSHB_PHOSU  (Q9QYB0), FSHB_PIG(P01228), 
FSHB_PONPY  (A1BN61), FSHB_RABIT  (Q6IY73), FSHB_RAT(P18427), 
FSHB_SAIBB  (Q3YC02), FSHB_SHEEP  (P01227), FSHB_STRCA  (P80663), 
FSHB_TRIVU  (O46430), GTHB1_ANGJA (Q9YGK3), GTHB1_CARAU (Q98848), 
GTHB1_CORAU (P48250), GTHB1_CYPCA (O13050), GTHB1_FUNHE (P30971), 
GTHB1_ICTPU (Q9DG81), GTHB1_MORSA (Q91120), GTHB1_ONCKE (P10257), 
GTHB1_ONCMA (P48252), GTHB1_THUOB (P37205), GTHB1_TRITC (Q9PW99), 
GTHB2_ACALA (Q90225), GTHB2_ANGAN (P27767), GTHB2_CARAU (Q98849), 
GTHB2_CLAGA (P53543), GTHB2_CLUPA (Q9YGH2), GTHB2_CORAU (P48251), 
GTHB2_CTEID (P30984), GTHB2_CYPCA (P01235), GTHB2_FUNHE (P30972), 
GTHB2_HYPMO (P37038), GTHB2_ICTPU (Q9DG80), GTHB2_MORSA (Q91121), 
GTHB2_ONCKE (P10256), GTHB2_ONCMA (P48253), GTHB2_ONCTS (P07732), 
GTHB2_THUOB (P37206), GTHB2_TRITC (Q9PW98), GTHB_MURCI  (P12837), 
LSHB_AILFU  (Q8HZR9), LSHB_AILME  (Q8WN18), LSHB_AQUCT  (P80071), 
LSHB_BALAC  (P33088), LSHB_BOVIN  (P04651), LSHB_CANLF  (P18842), 
LSHB_CERSI  (O77835), LSHB_COTJA  (P45657), LSHB_EQUAS  (P19794), 
LSHB_EQUQB  (O46641), LSHB_FELCA  (O77805), LSHB_GORGO  (Q2Q1P1), 
LSHB_HORSE  (P08751), LSHB_HUMAN  (P01229), LSHB_MACFA  (Q6EV78), 
LSHB_MELGA  (P45646), LSHB_MONDO  (Q95J85), LSHB_MOUSE  (O09108), 
LSHB_OSPRU  (O46483), LSHB_PANTA  (Q9BDI9), LSHB_PANTR  (Q2Q1P2), 
LSHB_PHYMC  (P25330), LSHB_PIG(P01232), LSHB_PONPY  (Q2Q1P0), 
LSHB_RABIT  (Q6IY74), LSHB_RAT(P01230), LSHB_SHEEP  (P01231), 
LSHB_STRCA  (P80664), LSHB_TRIVU  (O46482), TSHB_ANGAN  (Q08127), 
TSHB_ANGJA  (Q7ZZV4), TSHB_BOVIN  (P01223), TSHB_CANLF  (P54828), 
TSHB_CHICK  (O57340), TSHB_FELCA  (Q52R90), TSHB_HORSE  (Q28376), 
TSHB_HUMAN  (P01222), TSHB_LAMGL  (P79357), TSHB_MONDO  (Q95J88), 
TSHB_MOUSE  (P12656), TSHB_ONCMY  (P37240), TSHB_PHOSU  (Q62590), 
TSHB_PIG(P01224), TSHB_RAT(P04652), TSHB_SALSA  (O73824)
» more

UniProtKB/Swiss-Prot
False negative sequences		 3 sequences 

CGHB_SAIBB  (Q3S2X5), GPHB5_HUMAN (Q86YW7), GPHB5_MOUSE (Q812B2)


				
	

	

		UniProtKB/Swiss-Prot
'Partial' sequences		
		
			1 sequence
			


			
LSHB_PHOSU  (Q9QYA9)


				
	

	

		PDB
[Detailed view]		
		
			15 PDB
			


			1FL7; 1HCN; 1HRP; 1QFW; 1XWD; 4AY9; 4MQW; 6P57; 7FIG; 7FIH; 7FII; 7T9I; 
			
				7UTZ; 7XW5; 8I2G
			
			

			» more