PROSITE entry PS00697
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General information about the entry
| PURL [info] | https://purl.expasy.org/prosite/signature/PS00697 |
| Entry name [info] | DNA_LIGASE_A1 |
| Accession [info] | PS00697 |
| Entry type [info] | PATTERN |
| Date [info] |
01-DEC-1992 CREATED;
01-APR-2006 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00295 |
| Associated ProRule [info] | PRU10135 |
Name and characterization of the entry
| Description [info] | ATP-dependent DNA ligase AMP-binding site. |
| Pattern [info] |
[EDQH]-{K}-K-{VEDI}-[DN]-G-{GLYN}-R-[GACIVM].
|
Numerical results [info]
| Total number of hits | 209 in 204 different sequences |
| Number of true positive hits | 157 in 157 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 52 in 47 different sequences |
| Number of false negative sequences | 15 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 75.12 % |
| Recall (true positives / (true positives + false negatives)) | 91.28 % |
Comments [info]
| Taxonomic range [info] | Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses |
| Maximum number of repetitions [info] | 4 |
| Site [info] | active_site(?) at position 3 |
| Version [info] | 2 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
157 sequences
DNLI1_ARATH (Q42572), DNLI1_CAEEL (Q27474), DNLI1_DICDI (Q869E1), DNLI1_DROME (Q9W1H4), DNLI1_HALWD (Q18HT7), DNLI1_HUMAN (P18858), DNLI1_KORCO (B1L3K8), DNLI1_METAC (Q8TSR7), DNLI1_METBF (Q46C04), DNLI1_METMA (Q8PVR7), DNLI1_MOUSE (P37913), DNLI1_SCHPO (P12000), DNLI1_XENLA (P51892), DNLI1_YEAST (P04819), DNLI2_HALWD (Q18GX5), DNLI2_KORCO (B1L3V2), DNLI2_METAC (Q8TMT1), DNLI2_METBF (Q46BA3), DNLI2_METMA (Q8PTK1), DNLI2_THEPD (A1RY72), DNLI3_DICDI (Q54QM4), DNLI3_HUMAN (P49916), DNLI3_MOUSE (P97386), DNLI3_SCHPO (Q9C1W9), DNLI4_ARATH (Q9LL84), DNLI4_ASPFU (Q4WVG8), DNLI4_ASPOR (Q2U6A1), DNLI4_CANAL (P52496), DNLI4_CANGA (Q6FVD8), DNLI4_CHICK (Q90YB1), DNLI4_COCIM (Q1DKE7), DNLI4_COPC7 (A8N936), DNLI4_COPCI (Q7Z7W5), DNLI4_CRIGR (G3GTP0), DNLI4_CRYNB (P0CN09), DNLI4_CRYNJ (P0CN08), DNLI4_EMENI (Q5BH83), DNLI4_EREGS (Q75CA4), DNLI4_HUMAN (P49917), DNLI4_MOUSE (Q8BTF7), DNLI4_NEUCR (Q7SB49), DNLI4_ORYSJ (Q7X7E9), DNLI4_PHANO (Q0UCI9), DNLI4_PONAB (Q5R6L3), DNLI4_SCHPO (O74833), DNLI4_YEAST (Q08387), DNLI_ACIAM (Q02093), DNLI_AERPE (Q9YD18), DNLI_ANAD2 (B8JBM1), DNLI_ANADE (Q2IH69), DNLI_ANADF (A7HID3), DNLI_ANASK (B4UIS1), DNLI_AQUAE (O67398), DNLI_ARCFU (O29632), DNLI_ASFB7 (P35970), DNLI_ASFK5 (P0C992), DNLI_ASFM2 (P26813), DNLI_ASFP4 (P0C990), DNLI_ASFWA (P0C991), DNLI_BEUC1 (C5BW79), DNLI_BPT3 (P07717), DNLI_BPT4 (P00970), DNLI_BPT6 (P19088), DNLI_BPT7 (P00969), DNLI_CALMQ (A8MDU6), DNLI_CENSY (A0RWD6), DNLI_DICT6 (B5YD88), DNLI_DICTD (B8DZX8), DNLI_FOWPN (Q67480), DNLI_HALLT (B9LUZ9), DNLI_HALMA (Q5V4R0), DNLI_HALS3 (B0R4C9), DNLI_HALSA (Q9HR35), DNLI_HALVD (D4GYZ4), DNLI_HYPBU (A2BJX6), DNLI_IGNH4 (A8AB20), DNLI_KINRD (A6WG40), DNLI_KORVE (Q1II25), DNLI_META3 (A6UVC4), DNLI_METBU (Q12X08), DNLI_METJA (Q57635), DNLI_METKA (Q8TWN3), DNLI_METM5 (A4FY19), DNLI_METM6 (A9AAX4), DNLI_METM7 (A6VFQ9), DNLI_METMP (Q6LYM1), DNLI_METS5 (A4YD25), DNLI_METST (Q2NHF9), DNLI_METTF (P54875), DNLI_METTH (Q50566), DNLI_METTP (A0B7F9), DNLI_METVS (A6UNY0), DNLI_MONPV (A0A7H0DNE6), DNLI_MYCA1 (A0QJL0), DNLI_MYCBO (Q7TTR7), DNLI_MYCBP (A1KN60), DNLI_MYCBT (C1AGI1), DNLI_MYCGI (A4TDS2), DNLI_MYCMM (B2HHE1), DNLI_MYCPA (Q73V97), DNLI_MYCS2 (A0QUP1), DNLI_MYCSJ (A3PXE2), DNLI_MYCSK (A1UDY9), DNLI_MYCSS (Q1BB26), DNLI_MYCTA (A5U776), DNLI_MYCTO (P9WNV4), DNLI_MYCTU (P9WNV5), DNLI_MYCUA (A0PTC0), DNLI_MYCVP (A1T6P2), DNLI_NATPD (Q3IPX0), DNLI_NITMS (A9A3K1), DNLI_NOCFA (Q5YNY7), DNLI_NOCSJ (A1SKL2), DNLI_NPVLD (Q9YMV2), DNLI_OPITP (B1ZZL9), DNLI_PERMH (C0QSL7), DNLI_PSECP (B8HCE1), DNLI_PYRAB (P0CL75), DNLI_PYRAE (O93723), DNLI_PYRAR (A4WH24), DNLI_PYRAY (P0CL74), DNLI_PYRCJ (A3MS62), DNLI_PYRFU (P56709), DNLI_PYRHO (O59288), DNLI_PYRIL (A1RTK4), DNLI_PYRNV (B1YA52), DNLI_RHOJR (Q0SG75), DNLI_RHOOB (C1AX87), DNLI_SACEN (A4F870), DNLI_SACS2 (Q980T8), DNLI_SACSH (Q9P9K9), DNLI_SORC5 (A9GU24), DNLI_STAMF (A3DP49), DNLI_STRAW (Q826P6), DNLI_STRCO (Q9FCB1), DNLI_STRGG (B1W5J2), DNLI_SULAC (Q4JAM1), DNLI_SULIA (C3MZR1), DNLI_SULIK (C4KIZ2), DNLI_SULIL (C3MJ14), DNLI_SULIM (C3MYD2), DNLI_SULIN (C3NF77), DNLI_SULIY (C3N834), DNLI_SULTO (Q976G4), DNLI_SULZI (D2CJS7), DNLI_THEFM (Q9HH07), DNLI_THEKO (Q9HHC4), DNLI_THEON (B6YTR4), DNLI_VACCA (O57250), DNLI_VACCC (P20492), DNLI_VACCW (P16272), DNLI_VAR67 (P0DOO3), DNLI_VARV (P0DOO4), LIG6_ARATH (F4HPZ9), LIGC1_MYCS2 (A0R5T2), ROQA_PENRW (B6HJU6), Y1287_AQUAE (O67319)» more
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| UniProtKB/Swiss-Prot False negative sequences |
15 sequences
DNLI1_RAT (Q9JHY8), DNLI1_THEPD (A1RXA6), DNLI_HAEIN (P44121), DNLI_METAR (Q0W0X1), DNLI_METB6 (A7IAA9), DNLI_METHJ (Q2FTH4), DNLI_METLZ (A2SR38), DNLI_METMJ (A3CWP1), DNLI_METPE (B8GGB8), DNLI_METS3 (A5UKX2), DNLI_NANEQ (Q74M64), DNLI_PICTO (Q6L195), DNLI_THEAC (Q9HJ26), DNLI_THEVO (Q979A1), LIGD_BACSU (O34398)» more |
| UniProtKB/Swiss-Prot False positive sequences |
47 sequences
ACVS_AMYLA (P27743), ACVS_STRCL (Q01757), ALN_ORYSJ (B9FDB8), AMBB_PSEAE (Q9I1H0), BDP1_HUMAN (A6H8Y1), BDP1_MOUSE (Q571C7), BUAA_PETAA (A0A411L027), CCTN_TALIS (A0A0U1LQE6), CITS_BACSU (O34427), COX20_YEAST (Q04935), CPG1_PORG3 (B2RM93), DDHA_RHOSU (Q8GPG4), DHOM_LACLA (Q9CGD8), DHOM_LACLC (P52985), DLTA_LACLA (Q9CG49), DSBC_BORBR (Q7WEL4), DSBC_BORPA (Q7W396), DSBC_BORPE (Q7VU58), ERF99_ARATH (Q8L9K1), FABH_PROMM (Q7V4F6), FAU1_SULAC (Q4J9H1), FAU1_THEKO (Q5JHN3), FOLD_BUCAI (P57557), HAGA1_PORGI (P59915), HAGA2_PORGN (Q51845), HEPHL_ACRMI (B3EWZ9), HYUC_RHIML (Q6DTN4), INO80_MYCMD (Q4PGL2), KGP38_PORGN (P72194), KGP66_PORGN (P72197), KGP83_PORGN (Q51817), KGP_PORG3 (B2RLK2), KUP_ANADF (A7H902), LCSA_PURLI (A0A179H164), MNME_SULNB (A6QAL0), NLSA_EMENI (Q5BDY8), NRPS1_ASPFU (Q4WT66), NRPS4_GIBZE (I1RF49), NRPS8_ASPFU (Q4WVN4), PAL2_SOLTU (P31426), PDXB_PORGI (Q7MV70), PKS1_DICDI (Q55E72), QUEA_DEHM1 (Q3Z8C1), QUEA_STRGC (A8AYK5), RIMM_SYNR3 (A5GQ79), U518_AEDAE (Q17AI4), U518_ANOGA (Q7PZ36)» more |
| PDB [Detailed view] |
54 PDB
1A0I; 1X9N; 2CFM; 2HIV; 2HIX; 3GDE; 3L2P; 3VNN; 3W1B; 3W1G; 3W5O; 6BKF; 6BKG; 6DT1; 6IMJ; 6IMK; 6IML; 6IMN; 6P09; 6P0A; 6P0B; 6P0C; 6P0D; 6P0E; 6Q1V; 7KR3; 7KR4; 7L34; 7L35; 7LSY; 7LT3; 7NFC; 7NFE; 7QNZ; 7QO1; 7RPO; 7RPW; 7RPX; 7SUM; 7SX5; 7SXE; 8BH3; 8BHV; 8BHY; 8BOT; 8EZA; 8EZB; 8VDN; 8VDS; 8VDT; 8VZL; 8VZM; 9BS3; 9BS4 » more |