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PROSITE entry PS00711


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PURL: https://purl.expasy.org/prosite/signature/PS00711

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General information about the entry

Entry name [info] LIPOXYGENASE_1
Accession [info] PS00711
Entry type [info] PATTERN
Date [info] 01-DEC-1992 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00077

Name and characterization of the entry

Description [info] Lipoxygenases iron-binding region signature 1.
Pattern [info] 
[HQ]-[EQ]-x(3)-H-x-[LMA]-[NEQHRCS]-[GSTA]-H-[LIVMSTAC](2)-x-E.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 70 in 70 different sequences
Number of true positive hits 70 in 70 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 2
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 97.22 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] iron at position 4
Site [info] iron at position 9
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 70 sequences 

ALOX8_MOUSE (O35936), AOSL_PLEHO  (O16025), LOX11_SOLTU (P37831), 

LOX12_HUMAN (P18054), LOX12_MOUSE (P39655), LOX12_RAT   (F1LQ70), 
LOX12_SOLTU (O24379), LOX13_SOLTU (Q43189), LOX14_SOLTU (Q43190), 
LOX15_BOVIN (P27479), LOX15_HUMAN (P16050), LOX15_MOUSE (P39654), 
LOX15_PIG   (P16469), LOX15_PONAB (Q5RBE8), LOX15_RABIT (P12530), 
LOX15_RAT   (Q02759), LOX15_SOLTU (Q43191), LOX16_SOLTU (Q41238), 
LOX17_SOLTU (O22507), LOX18_SOLTU (O22508), LOX1_ARATH  (Q06327), 
LOX1_HORVU  (P29114), LOX1_LENCU  (P38414), LOX1_ORYSJ  (Q76I22), 
LOX1_SOYBN  (P08170), LOX1_TANCI  (R9WTS6), LOX21_HORVU (P93184), 
LOX21_SOLTU (O24370), LOX22_HORVU (Q8GSM3), LOX23_HORVU (Q8GSM2), 
LOX2_ARATH  (P38418), LOX2_ORYSJ  (P29250), LOX2_PEA(P14856), 
LOX2_SOYBN  (P09439), LOX2_TANCI  (R9WS04), LOX31_SOLTU (O24371), 
LOX3_ARATH  (Q9LNR3), LOX3_ORYSJ  (Q7G794), LOX3_PEA(P09918), 
LOX3_SOYBN  (P09186), LOX4_ARATH  (Q9FNX8), LOX4_ORYSJ  (Q53RB0), 
LOX4_SOYBN  (P38417), LOX5_ARATH  (Q9LUW0), LOX5_HUMAN  (P09917), 
LOX5_MESAU  (P51399), LOX5_MOUSE  (P48999), LOX5_ORYSJ  (Q7XV13), 
LOX5_RAT(P12527), LOX6_ARATH  (Q9CAG3), LOX6_ORYSJ  (Q8H016), 
LOXA_PHAVU  (P27480), LOXA_PSEAE  (Q9I4G8), LOXA_SOLLC  (P38415), 
LOXB_PHAVU  (P27481), LOXB_SOLLC  (P38416), LOXC1_ORYSJ (P38419), 
LOXC2_ORYSJ (Q84YK8), LOXE3_HUMAN (Q9BYJ1), LOXE3_MOUSE (Q9WV07), 
LOXE3_RAT   (D3ZKX9), LOXX_SOYBN  (P24095), LOX_PSEAI   (Q8RNT4), 
LX12B_HUMAN (O75342), LX12B_MOUSE (O70582), LX12B_RAT   (Q2KMM4), 
LX12E_MOUSE (P55249), LX12E_RAT   (D3ZQF9), LX15B_HUMAN (O15296), 
LX15B_RAT   (Q8K4F2)
» more

UniProtKB/Swiss-Prot
False negative sequences		 2 sequences 

LILIP_NOSS1 (Q8YK97), MNLOX_ASPFU (Q4WA38)


				
	

	

		PDB
[Detailed view]		
		
			66 PDB
			


			1F8N; 1FGM; 1FGQ; 1FGR; 1FGT; 1HU9; 1IK3; 1JNQ; 1LNH; 1LOX; 1N8Q; 1NO3; 
			
				1ROV; 1RRH; 1RRL; 1Y4K; 1YGE; 2FNQ; 2IUK; 2P0M; 2SBL; 3BNB; 3BNC; 3BND; 
				3BNE; 3D3L; 3DY5; 3FG1; 3FG3; 3FG4; 3O8Y; 3PZW; 3RDE; 3V92; 3V98; 3V99; 
				4G32; 4G33; 4NRE; 4QWT; 4RPE; 4WFO; 4WHA; 5EEO; 5IR4; 5IR5; 5LC8; 5T5V; 
				5TQN; 5TQO; 5TQP; 5TR0; 6N2W; 6NCF; 7LAF; 7SOI; 7SOJ; 7TTJ; 7TTK; 7TTL; 
				8GHB; 8GHC; 8GHD; 8GHE; 8I6Y; 8VIY
			
			

			» more