PROSITE entry PS00720
View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry
| PURL [info] | https://purl.expasy.org/prosite/signature/PS00720 |
| Entry name [info] | RASGEF |
| Accession [info] | PS00720 |
| Entry type [info] | PATTERN |
| Date [info] |
01-DEC-1992 CREATED;
01-APR-2003 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00594 |
Name and characterization of the entry
| Description [info] | Ras Guanine-nucleotide exchange factors domain signature. |
| Pattern [info] |
[VI]-P-[FYWVI]-x-[GPSV]-x(2)-[LIVMFYK]-x-[DNE]-[LIVM]-x(13,35)-[IVL]-N- [FYME]-x-K. |
Numerical results [info]
| Total number of hits | 67 in 67 different sequences |
| Number of true positive hits | 67 in 67 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 68 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 49.63 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
67 sequences
BUD5_YEAST (P25300), C3G_DROME (O77086), CDC25_CANAL (P43069), CDC25_LACKL (Q02342), CDC25_YEAST (P04821), GEFB_DICDI (Q8IS21), GEFC_DICDI (Q8IS20), GEFK_DICDI (Q54FF3), GEFS_DICDI (Q8SSW7), GEFV_DICDI (Q55FD8), GEFW_DICDI (Q55GH9), GNDS_HUMAN (Q12967), GNDS_MOUSE (Q03385), GNDS_RAT(Q03386), LTE1_CANGA (Q6FT12), LTE1_EREGS (Q75BH9), LTE1_KLULA (Q6CY10), LTE1_YEAST (P07866), RG1BA_DANRE (Q6DHR3), RG1BB_DANRE (Q6DBW1), RGF1B_BOVIN (A4IFE4), RGF1B_HUMAN (Q0VAM2), RGF1B_MOUSE (Q8JZL7), RGF1B_PONAB (Q5RC04), RGF1B_XENTR (Q28EC1), RGF1C_HUMAN (Q8N431), RGF1C_MACFA (Q95KH6), RGF1C_MOUSE (Q9D300), RGL1_DANRE (Q6P112), RGL1_HUMAN (Q9NZL6), RGL1_MOUSE (Q60695), RGL2_CANLF (Q5TJE5), RGL2_HUMAN (O15211), RGL2_MOUSE (Q61193), RGL3_HUMAN (Q3MIN7), RGL3_MOUSE (Q3UYI5), RGRF1_HUMAN (Q13972), RGRF1_MOUSE (P27671), RGRF1_RAT (P28818), RGRF2_DANRE (A2CEA7), RGRF2_HUMAN (O14827), RGRF2_MOUSE (P70392), RGRF2_RAT (Q99JE4), RPGF1_CAEEL (P34578), RPGF1_HUMAN (Q13905), RPGF3_HUMAN (O95398), RPGF3_MOUSE (Q8VCC8), RPGF3_RAT (Q9Z1C8), RPGF4_HUMAN (Q8WZA2), RPGF4_MOUSE (Q9EQZ6), RPGF4_RAT (Q9Z1C7), RPGF5_HUMAN (Q92565), RPGF5_MOUSE (Q8C0Q9), RPGF5_RAT (P83900), RPGF_CAEEL (G5EDB9), SDC25_YEAS1 (B3LTF3), SDC25_YEAS6 (B5VMS9), SDC25_YEAS7 (A7A0P0), SDC25_YEAS8 (C8ZCV7), SDC25_YEASX (P0CF32), SOS1_HUMAN (Q07889), SOS1_MOUSE (Q62245), SOS2_HUMAN (Q07890), SOS2_MOUSE (Q02384), SOS_DROME (P26675), STE6_SCHPO (P26674), YL016_YEAST (P0CF34)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
68 sequences
BCAR3_BOVIN (Q58DL5), BCAR3_HUMAN (O75815), BCAR3_MACFA (Q4R8R1), BCAR3_MOUSE (Q9QZK2), BCAR3_RAT (D3ZAZ5), BCAR3_XENLA (Q6INP9), BEM2_YEAST (P39960), EFC25_SCHPO (Q9USU1), GBPC_DICDI (Q8MVR1), GBPD_DICDI (Q54S40), GEFA_DICDI (Q54PQ4), GEFD_DICDI (Q8IS19), GEFE_DICDI (Q8IS18), GEFF_DICDI (Q54C94), GEFG_DICDI (Q8ST25), GEFH_DICDI (Q8IS16), GEFI_DICDI (Q8IS15), GEFJ_DICDI (Q8IS14), GEFL_DICDI (B0M0P8), GEFM_DICDI (Q8SSQ3), GEFN_DICDI (Q8IS12), GEFO_DICDI (Q8IS11), GEFP_DICDI (Q54TK8), GEFQ_DICDI (Q86G47), GEFR_DICDI (Q8SSQ0), GEFX_DICDI (Q55EC7), GEFY_DICDI (Q552M5), GRP1_HUMAN (O95267), GRP1_MOUSE (Q9Z1S3), GRP1_RAT(Q9R1K8), GRP1_XENLA (Q6NTL4), GRP1_XENTR (A4IJ06), GRP2A_XENLA (Q32N25), GRP2B_XENLA (Q6DCK3), GRP2_BOVIN (A6N9I4), GRP2_HUMAN (Q7LDG7), GRP2_MOUSE (Q9QUG9), GRP2_RAT(P0C643), GRP4_BOVIN (Q1LZ97), GRP4_HUMAN (Q8TDF6), GRP4_MOUSE (Q8BTM9), GRP4_RAT(Q8R5I4), KNDC1_HUMAN (Q76NI1), KNDC1_MOUSE (Q0KK55), PLCE1_HUMAN (Q9P212), PLCE1_MOUSE (Q8K4S1), PLCE1_RAT (Q99P84), RGDSR_HUMAN (Q8IZJ4), RGF1A_HUMAN (Q8N9B8), RGF1A_XENTR (A0JM95), RGPS1_CHICK (Q5ZJK0), RGPS1_DANRE (B0UXH6), RGPS1_HUMAN (Q5JS13), RGPS1_MOUSE (A2AR50), RGPS2_HUMAN (Q86X27), RGPS2_MACFA (Q4R7W3), RGPS2_MOUSE (Q9ERD6), RPGF2_BOVIN (F1MSG6), RPGF2_CANLF (F1PBJ0), RPGF2_HUMAN (Q9Y4G8), RPGF2_MOUSE (Q8CHG7), RPGF2_RAT (F1M386), RPGFL_HUMAN (Q9UHV5), RPGFL_MOUSE (Q68EF8), RPGFL_PONPY (Q5R9B2), SH2D3_HUMAN (Q8N5H7), SH2D3_MOUSE (Q9QZS8), SOS_CAEEL (Q9N5D3)» more |
| PDB [Detailed view] |
103 PDB
1BKD; 1NVU; 1NVV; 1NVW; 1NVX; 1XD2; 1XD4; 1XDV; 2BYV; 2II0; 2IJE; 3CF6; 3KSY; 4F7Z; 4JGW; 4MGI; 4MGK; 4MGY; 4MGZ; 4MH0; 4NYI; 4NYJ; 4NYM; 4URU; 4URV; 4URW; 4URX; 4URY; 4URZ; 4US0; 4US1; 4US2; 5CM8; 5CM9; 5OVD; 5OVE; 5OVF; 5OVG; 5OVH; 5OVI; 5WFO; 5WFP; 5WFQ; 5WFR; 6BVI; 6BVJ; 6BVK; 6BVL; 6BVM; 6CUO; 6CUP; 6CUR; 6D55; 6D56; 6D59; 6D5E; 6D5G; 6D5H; 6D5J; 6D5L; 6D5M; 6D5V; 6D5W; 6EIE; 6EPL; 6EPM; 6EPN; 6EPO; 6EPP; 6SCM; 6SFR; 6V94; 6V9F; 6V9J; 6V9L; 6V9M; 6V9N; 6V9O; 7AVI; 7AVL; 7AVS; 7AVT; 7AVU; 7AVV; 7KFZ; 7NZZ; 7UKR; 7UKS; 8BE2; 8BE4; 8BE5; 8BE6; 8BE7; 8BE8; 8BE9; 8BEA; 8T5G; 8T5M; 8T5R; 8UC9; 8UF2; 8UH0; 8XJJ » more |