Home  |  Contact
Entry: PS00720

General information about the entry

Entry name [info] RASGEF
Accession [info] PS00720
Entry type [info] PATTERN
Date [info] 01-DEC-1992 CREATED;
01-APR-2003 DATA UPDATE;
02-JUN-2021 INFO UPDATE.
PROSITE Doc. [info] PDOC00594

Name and characterization of the entry

Description [info] Ras Guanine-nucleotide exchange factors domain signature.
Pattern [info] 
[VI]-P-[FYWVI]-x-[GPSV]-x(2)-[LIVMFYK]-x-[DNE]-[LIVM]-x(13,35)-[IVL]-N-
[FYME]-x-K.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2021_03 which contains 565'254 sequence entries.


Total number of hits 67 in 67 different sequences
Number of true positive hits 67 in 67 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 68
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 49.63 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 67 sequences 

BUD5_YEAST  (P25300    ), C3G_DROME   (O77086    ), CDC25_CANAL (P43069    ), 

CDC25_LACKL (Q02342    ), CDC25_YEAST (P04821    ), GEFB_DICDI  (Q8IS21    ), 
GEFC_DICDI  (Q8IS20    ), GEFK_DICDI  (Q54FF3    ), GEFS_DICDI  (Q8SSW7    ), 
GEFV_DICDI  (Q55FD8    ), GEFW_DICDI  (Q55GH9    ), GNDS_HUMAN  (Q12967    ), 
GNDS_MOUSE  (Q03385    ), GNDS_RAT    (Q03386    ), LTE1_ASHGO  (Q75BH9    ), 
LTE1_CANGA  (Q6FT12    ), LTE1_KLULA  (Q6CY10    ), LTE1_YEAST  (P07866    ), 
RG1BA_DANRE (Q6DHR3    ), RG1BB_DANRE (Q6DBW1    ), RGF1B_BOVIN (A4IFE4    ), 
RGF1B_HUMAN (Q0VAM2    ), RGF1B_MOUSE (Q8JZL7    ), RGF1B_PONAB (Q5RC04    ), 
RGF1B_XENTR (Q28EC1    ), RGF1C_HUMAN (Q8N431    ), RGF1C_MACFA (Q95KH6    ), 
RGF1C_MOUSE (Q9D300    ), RGL1_DANRE  (Q6P112    ), RGL1_HUMAN  (Q9NZL6    ), 
RGL1_MOUSE  (Q60695    ), RGL2_CANLF  (Q5TJE5    ), RGL2_HUMAN  (O15211    ), 
RGL2_MOUSE  (Q61193    ), RGL3_HUMAN  (Q3MIN7    ), RGL3_MOUSE  (Q3UYI5    ), 
RGRF1_HUMAN (Q13972    ), RGRF1_MOUSE (P27671    ), RGRF1_RAT   (P28818    ), 
RGRF2_DANRE (A2CEA7    ), RGRF2_HUMAN (O14827    ), RGRF2_MOUSE (P70392    ), 
RGRF2_RAT   (Q99JE4    ), RPGF1_CAEEL (P34578    ), RPGF1_HUMAN (Q13905    ), 
RPGF3_HUMAN (O95398    ), RPGF3_MOUSE (Q8VCC8    ), RPGF3_RAT   (Q9Z1C8    ), 
RPGF4_HUMAN (Q8WZA2    ), RPGF4_MOUSE (Q9EQZ6    ), RPGF4_RAT   (Q9Z1C7    ), 
RPGF5_HUMAN (Q92565    ), RPGF5_MOUSE (Q8C0Q9    ), RPGF5_RAT   (P83900    ), 
RPGF_CAEEL  (G5EDB9    ), SDC25_YEAS1 (B3LTF3    ), SDC25_YEAS6 (B5VMS9    ), 
SDC25_YEAS7 (A7A0P0    ), SDC25_YEAS8 (C8ZCV7    ), SDC25_YEASX (P0CF32    ), 
SOS1_HUMAN  (Q07889    ), SOS1_MOUSE  (Q62245    ), SOS2_HUMAN  (Q07890    ), 
SOS2_MOUSE  (Q02384    ), SOS_DROME   (P26675    ), STE6_SCHPO  (P26674    ), 
YL016_YEAST (P0CF34    )
» more

UniProtKB/Swiss-Prot
False negative sequences		 68 sequences 

BCAR3_BOVIN (Q58DL5    ), BCAR3_HUMAN (O75815    ), BCAR3_MACFA (Q4R8R1    ), 

BCAR3_MOUSE (Q9QZK2    ), BCAR3_RAT   (D3ZAZ5    ), BCAR3_XENLA (Q6INP9    ), 
BEM2_YEAST  (P39960    ), EFC25_SCHPO (Q9USU1    ), GBPC_DICDI  (Q8MVR1    ), 
GBPD_DICDI  (Q54S40    ), GEFA_DICDI  (Q54PQ4    ), GEFD_DICDI  (Q8IS19    ), 
GEFE_DICDI  (Q8IS18    ), GEFF_DICDI  (Q54C94    ), GEFG_DICDI  (Q8ST25    ), 
GEFH_DICDI  (Q8IS16    ), GEFI_DICDI  (Q8IS15    ), GEFJ_DICDI  (Q8IS14    ), 
GEFL_DICDI  (B0M0P8    ), GEFM_DICDI  (Q8SSQ3    ), GEFN_DICDI  (Q8IS12    ), 
GEFO_DICDI  (Q8IS11    ), GEFP_DICDI  (Q54TK8    ), GEFQ_DICDI  (Q86G47    ), 
GEFR_DICDI  (Q8SSQ0    ), GEFX_DICDI  (Q55EC7    ), GEFY_DICDI  (Q552M5    ), 
GRP1_HUMAN  (O95267    ), GRP1_MOUSE  (Q9Z1S3    ), GRP1_RAT    (Q9R1K8    ), 
GRP1_XENLA  (Q6NTL4    ), GRP1_XENTR  (A4IJ06    ), GRP2A_XENLA (Q32N25    ), 
GRP2B_XENLA (Q6DCK3    ), GRP2_BOVIN  (A6N9I4    ), GRP2_HUMAN  (Q7LDG7    ), 
GRP2_MOUSE  (Q9QUG9    ), GRP2_RAT    (P0C643    ), GRP4_BOVIN  (Q1LZ97    ), 
GRP4_HUMAN  (Q8TDF6    ), GRP4_MOUSE  (Q8BTM9    ), GRP4_RAT    (Q8R5I4    ), 
KNDC1_HUMAN (Q76NI1    ), KNDC1_MOUSE (Q0KK55    ), PLCE1_HUMAN (Q9P212    ), 
PLCE1_MOUSE (Q8K4S1    ), PLCE1_RAT   (Q99P84    ), RGDSR_HUMAN (Q8IZJ4    ), 
RGF1A_HUMAN (Q8N9B8    ), RGF1A_XENTR (A0JM95    ), RGPS1_CHICK (Q5ZJK0    ), 
RGPS1_DANRE (B0UXH6    ), RGPS1_HUMAN (Q5JS13    ), RGPS1_MOUSE (A2AR50    ), 
RGPS2_HUMAN (Q86X27    ), RGPS2_MACFA (Q4R7W3    ), RGPS2_MOUSE (Q9ERD6    ), 
RPGF2_BOVIN (F1MSG6    ), RPGF2_CANLF (F1PBJ0    ), RPGF2_HUMAN (Q9Y4G8    ), 
RPGF2_MOUSE (Q8CHG7    ), RPGF2_RAT   (F1M386    ), RPGFL_HUMAN (Q9UHV5    ), 
RPGFL_MOUSE (Q68EF8    ), RPGFL_PONPY (Q5R9B2    ), SH2D3_HUMAN (Q8N5H7    ), 
SH2D3_MOUSE (Q9QZS8    ), SOS_CAEEL   (Q9N5D3    )
» more

PDB
[Detailed view]		 78 PDB

1BKD; 1NVU; 1NVV; 1NVW; 1NVX; 1XD2; 1XD4; 1XDV; 2BYV; 2II0; 2IJE; 3CF6; 3KSY; 4F7Z; 4JGW; 4MGI; 4MGK; 4MGY; 4MGZ; 4MH0; 4NYI; 4NYJ; 4NYM; 4URU; 4URV; 4URW; 4URX; 4URY; 4URZ; 4US0; 4US1; 4US2; 5CM8; 5CM9; 5OVD; 5OVE; 5OVF; 5OVG; 5OVH; 5OVI; 5WFO; 5WFP; 5WFQ; 5WFR; 6BVI; 6BVJ; 6BVK; 6BVL; 6BVM; 6CUO; 6CUP; 6CUR; 6D55; 6D56; 6D59; 6D5E; 6D5G; 6D5H; 6D5J; 6D5L; 6D5M; 6D5V; 6D5W; 6EIE; 6EPL; 6EPM; 6EPN; 6EPO; 6EPP; 6SCM; 6SFR; 6V94; 6V9F; 6V9J; 6V9L; 6V9M; 6V9N; 6V9O
» more

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission