PROSITE entry PS00720
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General information about the entry
| Entry name [info] | RASGEF |
| Accession [info] | PS00720 |
| Entry type [info] | PATTERN |
| Date [info] |
01-DEC-1992 CREATED;
01-APR-2003 DATA UPDATE; 08-NOV-2023 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00594 |
Name and characterization of the entry
| Description [info] | Ras Guanine-nucleotide exchange factors domain signature. |
| Pattern [info] |
[VI]-P-[FYWVI]-x-[GPSV]-x(2)-[LIVMFYK]-x-[DNE]-[LIVM]-x(13,35)-[IVL]-N- [FYME]-x-K. |
Numerical results [info]
| Total number of hits | 67 in 67 different sequences |
| Number of true positive hits | 67 in 67 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 68 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 49.63 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
67 sequences
BUD5_YEAST (P25300), C3G_DROME (O77086), CDC25_CANAL (P43069), CDC25_LACKL (Q02342), CDC25_YEAST (P04821), GEFB_DICDI (Q8IS21), GEFC_DICDI (Q8IS20), GEFK_DICDI (Q54FF3), GEFS_DICDI (Q8SSW7), GEFV_DICDI (Q55FD8), GEFW_DICDI (Q55GH9), GNDS_HUMAN (Q12967), GNDS_MOUSE (Q03385), GNDS_RAT(Q03386), LTE1_CANGA (Q6FT12), LTE1_EREGS (Q75BH9), LTE1_KLULA (Q6CY10), LTE1_YEAST (P07866), RG1BA_DANRE (Q6DHR3), RG1BB_DANRE (Q6DBW1), RGF1B_BOVIN (A4IFE4), RGF1B_HUMAN (Q0VAM2), RGF1B_MOUSE (Q8JZL7), RGF1B_PONAB (Q5RC04), RGF1B_XENTR (Q28EC1), RGF1C_HUMAN (Q8N431), RGF1C_MACFA (Q95KH6), RGF1C_MOUSE (Q9D300), RGL1_DANRE (Q6P112), RGL1_HUMAN (Q9NZL6), RGL1_MOUSE (Q60695), RGL2_CANLF (Q5TJE5), RGL2_HUMAN (O15211), RGL2_MOUSE (Q61193), RGL3_HUMAN (Q3MIN7), RGL3_MOUSE (Q3UYI5), RGRF1_HUMAN (Q13972), RGRF1_MOUSE (P27671), RGRF1_RAT (P28818), RGRF2_DANRE (A2CEA7), RGRF2_HUMAN (O14827), RGRF2_MOUSE (P70392), RGRF2_RAT (Q99JE4), RPGF1_CAEEL (P34578), RPGF1_HUMAN (Q13905), RPGF3_HUMAN (O95398), RPGF3_MOUSE (Q8VCC8), RPGF3_RAT (Q9Z1C8), RPGF4_HUMAN (Q8WZA2), RPGF4_MOUSE (Q9EQZ6), RPGF4_RAT (Q9Z1C7), RPGF5_HUMAN (Q92565), RPGF5_MOUSE (Q8C0Q9), RPGF5_RAT (P83900), RPGF_CAEEL (G5EDB9), SDC25_YEAS1 (B3LTF3), SDC25_YEAS6 (B5VMS9), SDC25_YEAS7 (A7A0P0), SDC25_YEAS8 (C8ZCV7), SDC25_YEASX (P0CF32), SOS1_HUMAN (Q07889), SOS1_MOUSE (Q62245), SOS2_HUMAN (Q07890), SOS2_MOUSE (Q02384), SOS_DROME (P26675), STE6_SCHPO (P26674), YL016_YEAST (P0CF34)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
68 sequences
BCAR3_BOVIN (Q58DL5), BCAR3_HUMAN (O75815), BCAR3_MACFA (Q4R8R1), BCAR3_MOUSE (Q9QZK2), BCAR3_RAT (D3ZAZ5), BCAR3_XENLA (Q6INP9), BEM2_YEAST (P39960), EFC25_SCHPO (Q9USU1), GBPC_DICDI (Q8MVR1), GBPD_DICDI (Q54S40), GEFA_DICDI (Q54PQ4), GEFD_DICDI (Q8IS19), GEFE_DICDI (Q8IS18), GEFF_DICDI (Q54C94), GEFG_DICDI (Q8ST25), GEFH_DICDI (Q8IS16), GEFI_DICDI (Q8IS15), GEFJ_DICDI (Q8IS14), GEFL_DICDI (B0M0P8), GEFM_DICDI (Q8SSQ3), GEFN_DICDI (Q8IS12), GEFO_DICDI (Q8IS11), GEFP_DICDI (Q54TK8), GEFQ_DICDI (Q86G47), GEFR_DICDI (Q8SSQ0), GEFX_DICDI (Q55EC7), GEFY_DICDI (Q552M5), GRP1_HUMAN (O95267), GRP1_MOUSE (Q9Z1S3), GRP1_RAT(Q9R1K8), GRP1_XENLA (Q6NTL4), GRP1_XENTR (A4IJ06), GRP2A_XENLA (Q32N25), GRP2B_XENLA (Q6DCK3), GRP2_BOVIN (A6N9I4), GRP2_HUMAN (Q7LDG7), GRP2_MOUSE (Q9QUG9), GRP2_RAT(P0C643), GRP4_BOVIN (Q1LZ97), GRP4_HUMAN (Q8TDF6), GRP4_MOUSE (Q8BTM9), GRP4_RAT(Q8R5I4), KNDC1_HUMAN (Q76NI1), KNDC1_MOUSE (Q0KK55), PLCE1_HUMAN (Q9P212), PLCE1_MOUSE (Q8K4S1), PLCE1_RAT (Q99P84), RGDSR_HUMAN (Q8IZJ4), RGF1A_HUMAN (Q8N9B8), RGF1A_XENTR (A0JM95), RGPS1_CHICK (Q5ZJK0), RGPS1_DANRE (B0UXH6), RGPS1_HUMAN (Q5JS13), RGPS1_MOUSE (A2AR50), RGPS2_HUMAN (Q86X27), RGPS2_MACFA (Q4R7W3), RGPS2_MOUSE (Q9ERD6), RPGF2_BOVIN (F1MSG6), RPGF2_CANLF (F1PBJ0), RPGF2_HUMAN (Q9Y4G8), RPGF2_MOUSE (Q8CHG7), RPGF2_RAT (F1M386), RPGFL_HUMAN (Q9UHV5), RPGFL_MOUSE (Q68EF8), RPGFL_PONPY (Q5R9B2), SH2D3_HUMAN (Q8N5H7), SH2D3_MOUSE (Q9QZS8), SOS_CAEEL (Q9N5D3)» more |
| PDB [Detailed view] |
93 PDB
1BKD; 1NVU; 1NVV; 1NVW; 1NVX; 1XD2; 1XD4; 1XDV; 2BYV; 2II0; 2IJE; 3CF6; 3KSY; 4F7Z; 4JGW; 4MGI; 4MGK; 4MGY; 4MGZ; 4MH0; 4NYI; 4NYJ; 4NYM; 4URU; 4URV; 4URW; 4URX; 4URY; 4URZ; 4US0; 4US1; 4US2; 5CM8; 5CM9; 5OVD; 5OVE; 5OVF; 5OVG; 5OVH; 5OVI; 5WFO; 5WFP; 5WFQ; 5WFR; 6BVI; 6BVJ; 6BVK; 6BVL; 6BVM; 6CUO; 6CUP; 6CUR; 6D55; 6D56; 6D59; 6D5E; 6D5G; 6D5H; 6D5J; 6D5L; 6D5M; 6D5V; 6D5W; 6EIE; 6EPL; 6EPM; 6EPN; 6EPO; 6EPP; 6SCM; 6SFR; 6V94; 6V9F; 6V9J; 6V9L; 6V9M; 6V9N; 6V9O; 7AVI; 7AVL; 7AVS; 7AVT; 7AVU; 7AVV; 7KFZ; 7NZZ; 7UKR; 7UKS; 8BE6; 8BE7; 8BE8; 8BE9; 8BEA » more |