PROSITE logo

PROSITE entry PS00721


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] FTHFS_1
Accession [info] PS00721
Entry type [info] PATTERN
Date [info] 01-DEC-1992 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00595

Name and characterization of the entry

Description [info] Formate--tetrahydrofolate ligase signature 1.
Pattern [info]
[GN]-[LIVMS]-K-G-[GST]-[AG]-[AST]-G-[GAS]-G-[YLHRKF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 297 in 297 different sequences
Number of true positive hits 297 in 297 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 16
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 94.89 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
297 sequences

C1TC_DROME  (O96553), C1TC_HUMAN  (P11586), C1TC_MOUSE  (Q922D8), 
C1TC_PONAB  (Q5R8P0), C1TC_RAT(P27653), C1TC_SCHPO  (Q8WZJ7), 
C1TC_SPOFR  (Q27772), C1TC_YEAST  (P07245), C1TM_BOVIN  (Q0VCR7), 
C1TM_HUMAN  (Q6UB35), C1TM_MOUSE  (Q3V3R1), C1TM_SCHPO  (O43007), 
C1TM_YEAST  (P09440), FTHS1_DESHY (Q251P8), FTHS1_LACAC (Q5FJY2), 
FTHS1_RUBXD (Q1AXZ4), FTHS1_STRP1 (Q99ZI9), FTHS1_STRP3 (P0DF90), 
FTHS1_STRP6 (Q5XC12), FTHS1_STRP8 (Q8P0X5), FTHS1_STRPB (Q1JBM0), 
FTHS1_STRPC (Q1JLK2), FTHS1_STRPD (Q1JGN8), FTHS1_STRPF (Q1J6F7), 
FTHS1_STRPG (A2REC4), FTHS1_STRPM (Q48TE8), FTHS1_STRPQ (P0DF91), 
FTHS1_STRSV (A3CL27), FTHS2_DESHY (Q24ZZ8), FTHS2_LACAC (Q5FIU5), 
FTHS2_RUBXD (Q1AVP8), FTHS2_STRP1 (Q99XR2), FTHS2_STRP3 (P0DF92), 
FTHS2_STRP6 (Q5X9K7), FTHS2_STRP8 (Q8NZ49), FTHS2_STRPB (Q1J9F2), 
FTHS2_STRPC (Q1JJK1), FTHS2_STRPD (Q1JEK4), FTHS2_STRPF (Q1J4C0), 
FTHS2_STRPG (A2RGS2), FTHS2_STRPM (Q48QZ2), FTHS2_STRPQ (P0DF93), 
FTHS2_STRSV (A3CN49), FTHS3_RUBXD (Q1AT39), FTHS_ACET2  (A3DI22), 
FTHS_ACTP2  (A3MZI4), FTHS_ACTP7  (B3GX43), FTHS_AERHH  (A0KIN9), 
FTHS_AERS4  (A4SPE5), FTHS_AGARV  (C4ZBG8), FTHS_ALIF1  (Q5E3V8), 
FTHS_ALIFM  (B5FG96), FTHS_ALISL  (B6EIJ9), FTHS_ALKOO  (A8MIN1), 
FTHS_ALLAM  (B9JZN5), FTHS_ARATH  (Q9SPK5), FTHS_ARTS2  (A0JZ10), 
FTHS_BACAA  (C3P858), FTHS_BACAC  (C3LKJ6), FTHS_BACAH  (A0RD97), 
FTHS_BACAN  (Q81RE1), FTHS_BACC0  (B7JLG8), FTHS_BACC1  (Q739F4), 
FTHS_BACC2  (B7IUA4), FTHS_BACC3  (C1ES77), FTHS_BACC7  (B7HP29), 
FTHS_BACCQ  (B9IYP4), FTHS_BACCR  (Q81E87), FTHS_BACCZ  (Q63C61), 
FTHS_BACFN  (Q5LD60), FTHS_BACFR  (Q64U80), FTHS_BACHK  (Q6HJK9), 
FTHS_BACLD  (Q65IA6), FTHS_BACP2  (A8FEC9), FTHS_BACTN  (Q8A9S8), 
FTHS_BART1  (A9IM41), FTHS_BIFLO  (Q8G700), FTHS_CALS4  (Q8R7L3), 
FTHS_CAMC1  (A8Z6G1), FTHS_CAMC5  (A7GZZ0), FTHS_CARHZ  (Q3A9K2), 
FTHS_CERS1  (A3PM52), FTHS_CERS4  (Q3J047), FTHS_CERS5  (A4WQ11), 
FTHS_CERSK  (B9KLK4), FTHS_CHESB  (Q11G79), FTHS_CHLAA  (A9WIW3), 
FTHS_CHLAD  (B8GC03), FTHS_CHLSY  (B9LKW0), FTHS_CLOAB  (Q97EB3), 
FTHS_CLOAC  (P13419), FTHS_CLOB1  (A7FZB0), FTHS_CLOB6  (C3KVU4), 
FTHS_CLOB8  (A6LPL1), FTHS_CLOBA  (B2UXU5), FTHS_CLOBB  (B2TI29), 
FTHS_CLOBH  (A5I7P9), FTHS_CLOBJ  (C1FND0), FTHS_CLOBK  (B1IGY1), 
FTHS_CLOBL  (A7GJB8), FTHS_CLOBM  (B1KTC6), FTHS_CLOCY  (Q07064), 
FTHS_CLOD6  (Q189R2), FTHS_CLOK1  (B9DYW1), FTHS_CLOK5  (A5N5B3), 
FTHS_CLONN  (A0PXN0), FTHS_CLOP1  (Q0TMI3), FTHS_CLOPE  (Q8XHL4), 
FTHS_CLOPS  (Q0SQ82), FTHS_CLOTE  (Q891R3), FTHS_CORDI  (Q6NH87), 
FTHS_CORJK  (Q4JVW2), FTHS_CUTAK  (Q6ABS5), FTHS_DEHM1  (Q3Z8K3), 
FTHS_DEHMC  (Q3ZX40), FTHS_DESAH  (C0QAX9), FTHS_DESDA  (B8J0C2), 
FTHS_DESPS  (Q6AL19), FTHS_DESRM  (A4J0S6), FTHS_DINSH  (A8LIR1), 
FTHS_ELUMP  (B2KDK9), FTHS_ENTFA  (Q834D6), FTHS_FERNB  (A7HLZ4), 
FTHS_FINM2  (B0S0G1), FTHS_FUSNN  (Q8RHF4), FTHS_GRABC  (Q0BW57), 
FTHS_HAEDU  (Q7VLW6), FTHS_HALMA  (Q5V5Y2), FTHS_HALOH  (B8D067), 
FTHS_HALWD  (Q18JB5), FTHS_HELMI  (B0TBP1), FTHS_HERA2  (A9B4H8), 
FTHS_HYPNA  (Q0BX04), FTHS_JANSC  (Q28TR4), FTHS_KOSOT  (C5CI89), 
FTHS_LACCB  (B3WEG3), FTHS_LACDA  (Q1GA94), FTHS_LACDB  (Q04AM0), 
FTHS_LACE2  (C4Z1V6), FTHS_LACGA  (Q043I0), FTHS_LACJO  (Q74JC1), 
FTHS_LACLA  (Q9CH07), FTHS_LACLM  (A2RLK1), FTHS_LACLS  (Q02ZS7), 
FTHS_LACP3  (Q038Y4), FTHS_LACP7  (A9KNJ5), FTHS_LACPL  (Q88W76), 
FTHS_LATSS  (Q38X32), FTHS_LAWIP  (Q1MPZ9), FTHS_LEUMM  (Q03YB1), 
FTHS_LEVBA  (Q03S45), FTHS_LIGS1  (Q1WTW0), FTHS_LIMF3  (B2GF64), 
FTHS_LIMRD  (A5VHS9), FTHS_LIMRJ  (B2G5A9), FTHS_LISIN  (Q92AD2), 
FTHS_LISMC  (C1KWH6), FTHS_LISMF  (Q71YD9), FTHS_LISMH  (B8DDM6), 
FTHS_LISMO  (Q8Y624), FTHS_LISW6  (A0AJY2), FTHS_MALP2  (Q8EUQ1), 
FTHS_METC4  (B7L0A5), FTHS_METCA  (Q605Q9), FTHS_METEA  (Q83WS0), 
FTHS_METEP  (A9VZT0), FTHS_METFK  (Q1GZ16), FTHS_METLZ  (A2SS72), 
FTHS_METNO  (B8IBS4), FTHS_METPB  (B1ZJ88), FTHS_METPP  (A2SKX8), 
FTHS_METRJ  (B1M0D1), FTHS_METS4  (B0UQF5), FTHS_METSB  (B8EKB9), 
FTHS_MOOTA  (Q2RM91), FTHS_MOOTH  (P21164), FTHS_NATTJ  (B2A3Q6), 
FTHS_NEIG1  (Q5FAG1), FTHS_NEIG2  (B4RP08), FTHS_NEIM0  (A9M1J1), 
FTHS_NEIMA  (Q9JVY8), FTHS_NEIMB  (Q9JXY2), FTHS_NEIMF  (A1KS57), 
FTHS_NOCSJ  (A1SQH3), FTHS_OENOB  (Q04FS6), FTHS_PAEAT  (A1R8N9), 
FTHS_PARD8  (A6LAR6), FTHS_PARDP  (A1B1M8), FTHS_PEDPA  (Q03FM6), 
FTHS_PELUB  (Q4FL49), FTHS_PEPAC  (Q5XZD9), FTHS_PETMO  (A9BIV8), 
FTHS_PHOPR  (Q6LNJ0), FTHS_PHOV8  (A6L4P0), FTHS_PICTO  (Q6KZM3), 
FTHS_PORGI  (Q7MUZ8), FTHS_PROMH  (B4ET09), FTHS_PSELT  (A8F7D5), 
FTHS_PSYWF  (A5WI04), FTHS_RENSM  (A9WMW3), FTHS_RHIE6  (B3PV59), 
FTHS_RHIEC  (Q2K5P2), FTHS_RHIJ3  (Q1MDG4), FTHS_RHILO  (Q98HQ4), 
FTHS_RHILW  (B5ZYA2), FTHS_RHIME  (Q92N42), FTHS_RHIR8  (B9J7E8), 
FTHS_ROSCS  (A7NGQ9), FTHS_ROSDO  (Q160C2), FTHS_ROSS1  (A5UPV2), 
FTHS_RUEPO  (Q5LNV0), FTHS_RUMCH  (B8I3S9), FTHS_SACEN  (A4FL80), 
FTHS_SHEAM  (A1SAE2), FTHS_SHEB2  (B8ECE1), FTHS_SHEB5  (A3CZY6), 
FTHS_SHEB8  (A6WSY9), FTHS_SHEB9  (A9L3Z6), FTHS_SHELP  (A3QA17), 
FTHS_SHEON  (Q8EJA7), FTHS_SHEPC  (A4YAP3), FTHS_SHEPW  (B8CI99), 
FTHS_SHESA  (A0KSN0), FTHS_SHESH  (A8FQV1), FTHS_SHESM  (Q0HMS6), 
FTHS_SHESR  (Q0HR05), FTHS_SHESW  (A1RFN3), FTHS_SHEWM  (B1KJC0), 
FTHS_SINFN  (C3MFQ8), FTHS_SINMW  (A6UBV0), FTHS_SPHSK  (O66164), 
FTHS_SPIOL  (P28723), FTHS_STAA1  (A7X3G5), FTHS_STAA2  (A6U2J8), 
FTHS_STAA3  (Q2FG06), FTHS_STAA8  (Q2G296), FTHS_STAA9  (A5ITQ4), 
FTHS_STAAB  (Q2YTF6), FTHS_STAAC  (Q5HF42), FTHS_STAAE  (A6QHR5), 
FTHS_STAAM  (Q99TD2), FTHS_STAAN  (Q7A535), FTHS_STAAR  (Q6GFX6), 
FTHS_STAAS  (Q6G8J5), FTHS_STAAT  (A8Z2Q0), FTHS_STAAW  (Q8NW37), 
FTHS_STACT  (B9DN77), FTHS_STAEQ  (Q5HNH4), FTHS_STAES  (Q8CNV9), 
FTHS_STAHJ  (Q4L776), FTHS_STRA1  (Q3K138), FTHS_STRA3  (Q8E5E3), 
FTHS_STRA5  (Q8DZP5), FTHS_STRE4  (C0M9N3), FTHS_STREM  (B4U2T6), 
FTHS_STRMU  (Q59925), FTHS_STRP2  (Q04K90), FTHS_STRP4  (B5E4W4), 
FTHS_STRP7  (C1C7J4), FTHS_STRPI  (B1IC26), FTHS_STRPJ  (B8ZJQ0), 
FTHS_STRPN  (Q97QI2), FTHS_STRPS  (B2IPQ3), FTHS_STRR6  (Q8DPL5), 
FTHS_STRS2  (A4W0G0), FTHS_STRS7  (C0MFU5), FTHS_STRSY  (A4VU67), 
FTHS_STRT1  (Q5M083), FTHS_STRT2  (Q5M4U2), FTHS_STRTD  (Q03L41), 
FTHS_STRU0  (B9DS83), FTHS_STRZJ  (C1CEI6), FTHS_STRZP  (C1CKW9), 
FTHS_STRZT  (C1CR74), FTHS_SYMTH  (Q67JH9), FTHS_SYNAS  (Q2LU82), 
FTHS_SYNWW  (Q0AX38), FTHS_THEAB  (B7IG29), FTHS_THEAC  (Q9HI67), 
FTHS_THEM4  (A6LJS5), FTHS_THEMA  (Q9X287), FTHS_THEP1  (A5ILJ8), 
FTHS_THEP3  (B0KC36), FTHS_THEPX  (B0K5A5), FTHS_THESQ  (B1LAQ7), 
FTHS_THET2  (Q72GY9), FTHS_THEVO  (Q97CL3), FTHS_THEYD  (B5YJE1), 
FTHS_TREDE  (Q73RR6), FTHS_UREPA  (Q9PQS1), FTHS_VIBA3  (B7VSJ2), 
FTHS_VIBC1  (A7N5E9), FTHS_VIBCH  (Q9KLX7), FTHS_VIBPA  (Q87HX2), 
FTHS_VIBVU  (Q8D7D8), FTHS_VIBVY  (Q7MEE8), FTHS_ZYMMO  (Q5NQC7)
» more

UniProtKB/Swiss-Prot
False negative sequences
16 sequences

FTHS_ACHLI  (A9NE95), FTHS_ACICJ  (A5G276), FTHS_BEII9  (B2IC30), 
FTHS_BRAHW  (C0QX38), FTHS_CALBD  (B9MM59), FTHS_CALS8  (A4XIU2), 
FTHS_DESAL  (B8FGU7), FTHS_DESOH  (A8ZZJ0), FTHS_LEUCK  (B1MY45), 
FTHS_MARMM  (Q0APT3), FTHS_MYXXD  (Q1DFW5), FTHS_RUEST  (Q1GE26), 
FTHS_SHEHH  (B0TVP3), FTHS_SHEPA  (A8H8Z4), FTHS_SYNFM  (A0LLR3), 
FTHS_YERE8  (A1JMA3)
» more

PDB
[Detailed view]
14 PDB

1EG7; 1FP7; 1FPM; 3DO6; 3QUS; 4IOJ; 4IOK; 4IOL; 4IOM; 4JIM; 4JJK; 4JJZ; 4JKI; 7C11
» more