PROSITE logo

PROSITE entry PS00726


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] AP_NUCLEASE_F1_1
Accession [info] PS00726
Entry type [info] PATTERN
Date [info] 01-DEC-1992 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00598

Name and characterization of the entry

Description [info] AP endonucleases family 1 signature 1.
Pattern [info]
[APF]-D-[LIVMF](2)-{T}-[LIVM]-Q-E-{G}-K.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 25 in 25 different sequences
Number of true positive hits 25 in 25 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 5
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 83.33 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] metal(?) at position 7
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
25 sequences

APEA_DICDI  (P51173), APEX1_BOVIN (P23196), APEX1_DANRE (A0MTA1), 
APEX1_GORGO (A1YES6), APEX1_HUMAN (P27695), APEX1_MOUSE (P28352), 
APEX1_PANPA (A1YFZ3), APEX1_PANTR (A2T6Y4), APEX1_PONPY (A2T7I6), 
APEX1_RAT   (P43138), APEX2_BOVIN (Q5E9N9), APEX2_HUMAN (Q9UBZ4), 
APEX2_MOUSE (Q68G58), APEX2_XENLA (Q6DDT4), APN2_SCHPO  (P87175), 
ARP_ARATH   (P45951), EX3_ECOLI   (P09030), EX3_HAEIN   (P44318), 
EX3_SALTI   (P0A1B0), EX3_SALTY   (P0A1A9), EXOA_BACSU  (P37454), 
EXOA_STRPN  (P0A2X3), EXOA_STRR6  (P0A2X4), RRP1_DROME  (P27864), 
UREND_METTH (O26314)
» more

UniProtKB/Swiss-Prot
False negative sequences
5 sequences

APE1L_ARATH (Q5XF07), APE2_ARATH  (F4JNY0), APEX_PLABA  (A0A509ADV9), 
APEX_PLAF7  (O97240), APN2_YEAST  (P38207)
» more

PDB
[Detailed view]
78 PDB

1AKO; 1BIX; 1DE8; 1DE9; 1DEW; 1E9N; 1HD7; 2ISI; 2O3C; 2O3H; 3FZI; 3G00; 3G0A; 3G0R; 3G1K; 3G2C; 3G2D; 3G38; 3G3C; 3G3Y; 3G4T; 3G8V; 3G91; 3GA6; 3U8U; 3W2X; 3W2Y; 4IEM; 4LND; 4QH9; 4QHD; 4QHE; 5CFE; 5CFG; 5DFF; 5DFH; 5DFI; 5DG0; 5WN0; 5WN1; 5WN3; 5WN4; 5WN5; 6BOQ; 6BOS; 6BOT; 6BOU; 6BOW; 6MK3; 6MKK; 6MKM; 6MKO; 6P94; 6W0Q; 6W2P; 6W3L; 6W3N; 6W3Q; 6W3U; 6W43; 6W4I; 6W4T; 6WCD; 7CD5; 7CD6; 7LPG; 7LPH; 7LPI; 7LPJ; 7MCR; 7MEV; 7TC2; 7TC3; 7TR7; 7U50; 8KA3; 8KA4; 8KA5
» more