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PROSITE entry PS00727


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General information about the entry

Entry name [info] AP_NUCLEASE_F1_2
Accession [info] PS00727
Entry type [info] PATTERN
Date [info] 01-DEC-1992 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00598

Name and characterization of the entry

Description [info] AP endonucleases family 1 signature 2.
Pattern [info]
D-[ST]-[FY]-[RP]-[KHQ]-x(7,8)-[FYWD]-[ST]-[FYW](2).

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 19 in 19 different sequences
Number of true positive hits 19 in 19 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 11
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 63.33 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
19 sequences

APEA_DICDI  (P51173), APEX1_BOVIN (P23196), APEX1_GORGO (A1YES6), 
APEX1_HUMAN (P27695), APEX1_MOUSE (P28352), APEX1_PANPA (A1YFZ3), 
APEX1_PANTR (A2T6Y4), APEX1_PONPY (A2T7I6), APEX1_RAT   (P43138), 
APN2_SCHPO  (P87175), ARP_ARATH   (P45951), EX3_ECOLI   (P09030), 
EX3_HAEIN   (P44318), EX3_SALTI   (P0A1B0), EX3_SALTY   (P0A1A9), 
EXOA_BACSU  (P37454), EXOA_STRPN  (P0A2X3), EXOA_STRR6  (P0A2X4), 
RRP1_DROME  (P27864)
» more

UniProtKB/Swiss-Prot
False negative sequences
11 sequences

APE1L_ARATH (Q5XF07), APE2_ARATH  (F4JNY0), APEX1_DANRE (A0MTA1), 
APEX2_BOVIN (Q5E9N9), APEX2_HUMAN (Q9UBZ4), APEX2_MOUSE (Q68G58), 
APEX2_XENLA (Q6DDT4), APEX_PLABA  (A0A509ADV9), APEX_PLAF7  (O97240), 
APN2_YEAST  (P38207), UREND_METTH (O26314)
» more

PDB
[Detailed view]
66 PDB

1AKO; 1BIX; 1DE8; 1DE9; 1DEW; 1E9N; 1HD7; 2ISI; 2O3H; 3U8U; 4IEM; 4LND; 4QH9; 4QHD; 4QHE; 5CFE; 5CFG; 5DFF; 5DFH; 5DFI; 5DFJ; 5DG0; 5WN0; 5WN1; 5WN2; 5WN4; 5WN5; 6BOQ; 6BOR; 6BOS; 6BOT; 6BOU; 6BOV; 6BOW; 6MK3; 6MKK; 6MKM; 6MKO; 6P93; 6P94; 6W0Q; 6W2P; 6W3L; 6W3N; 6W3Q; 6W3U; 6W43; 6W4I; 6W4T; 7CD5; 7CD6; 7LPG; 7LPH; 7LPI; 7LPJ; 7MCR; 7MEV; 7SUV; 7SVB; 7TC2; 7TC3; 7TR7; 7U50; 8KA3; 8KA4; 8KA5
» more