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PROSITE entry PS00729


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General information about the entry

Entry name [info] AP_NUCLEASE_F2_1
Accession [info] PS00729
Entry type [info] PATTERN
Date [info] 01-DEC-1992 CREATED;
01-DEC-2001 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00599

Name and characterization of the entry

Description [info] AP endonucleases family 2 signature 1.
Pattern [info]
H-[GSAD]-x-Y-[LIF]-[LIMN]-N-[LIVMFCAP]-[AGC].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 238 in 238 different sequences
Number of true positive hits 233 in 233 different sequences
Number of 'unknown' hits 0
Number of false positive hits 5 in 5 different sequences
Number of false negative sequences 44
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 97.90 %
Recall (true positives / (true positives + false negatives)) 84.12 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] zinc at position 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
233 sequences

APN1_CAEEL  (Q10002), APN1_PLABA  (A0A509ASK2), APN1_PLAF7  (Q8IE02), 
APN1_SCHPO  (P50525), APN1_YEAST  (P22936), END4_ACHLI  (A9NFH1), 
END4_ACTP2  (A3MZ76), END4_ACTP7  (B3H0M0), END4_ACTPJ  (B0BTA9), 
END4_AERHH  (A0KK26), END4_AERS4  (A4SMZ0), END4_ALIB4  (A8EWW1), 
END4_ANOFW  (B7GH81), END4_AQUAE  (O67551), END4_AYWBP  (Q2NJF9), 
END4_BACAA  (C3P8J1), END4_BACAC  (C3LKW3), END4_BACAH  (A0RIQ8), 
END4_BACAN  (Q81LV1), END4_BACC0  (B7JN09), END4_BACC2  (B7IYD6), 
END4_BACC3  (C1ES07), END4_BACC4  (B7HCQ9), END4_BACC7  (B7HPI4), 
END4_BACCN  (A7GSY1), END4_BACCQ  (B9IY53), END4_BACCR  (Q818H3), 
END4_BACCZ  (Q634Q3), END4_BACFN  (Q5LG28), END4_BACFR  (Q64WY5), 
END4_BACHK  (Q6HDN3), END4_BACLD  (Q65HA0), END4_BACMK  (A9VHR4), 
END4_BACSU  (P54476), END4_BACTN  (Q89YT0), END4_BACVZ  (A7Z6S8), 
END4_BUCA5  (B8D8T8), END4_BUCAI  (P57237), END4_BUCAP  (P59058), 
END4_BUCAT  (B8D742), END4_BUCBP  (P59496), END4_CAMC1  (A8Z6D9), 
END4_CAMC5  (A7GW36), END4_CAMHC  (A7I010), END4_CHLAA  (A9WII8), 
END4_CHLAB  (Q5L798), END4_CHLAD  (B8G418), END4_CHLCH  (Q3AT74), 
END4_CHLCV  (Q824X6), END4_CHLL2  (B3EEJ7), END4_CHLL3  (Q3B5R5), 
END4_CHLMU  (Q9PJB8), END4_CHLP8  (B3QQA9), END4_CHLPB  (B3ELV8), 
END4_CHLPM  (A4SDE2), END4_CHLPN  (Q9Z7H3), END4_CHLSY  (B9LAM9), 
END4_CHLT2  (B0B8K0), END4_CHLTA  (Q3KL70), END4_CHLTB  (B0BA79), 
END4_CHLTE  (Q8KFL0), END4_CHLTR  (O84630), END4_CITBB  (B5EAS8), 
END4_CITK8  (A8AE66), END4_DESAH  (C0QMG1), END4_DESOH  (A8ZSE7), 
END4_DESPS  (Q6ASE4), END4_DICDI  (Q966U0), END4_ECO24  (A7ZNY3), 
END4_ECO27  (B7UFH5), END4_ECO45  (B7MF74), END4_ECO55  (B7LAI2), 
END4_ECO57  (P0A6C2), END4_ECO5E  (B5YWV0), END4_ECO7I  (B7NMX3), 
END4_ECO81  (B7MX24), END4_ECO8A  (B7M507), END4_ECOBW  (C4ZU09), 
END4_ECODH  (B1X857), END4_ECOHS  (A8A222), END4_ECOK1  (A1AD18), 
END4_ECOL5  (Q0TFT1), END4_ECOL6  (Q8FFU0), END4_ECOLC  (B1IYB0), 
END4_ECOLI  (P0A6C1), END4_ECOLU  (B7N5C2), END4_ECOSE  (B6I8L0), 
END4_ECOSM  (B1LKQ6), END4_ECOUT  (Q1R9R2), END4_EDWI9  (C5BCN2), 
END4_ENT38  (A4WCJ5), END4_ENTFA  (Q834D0), END4_ERWT9  (B2VIH1), 
END4_ESCF3  (B7LVB9), END4_EXIS2  (B1YL88), END4_GEODF  (B9M4N1), 
END4_GEOKA  (Q5KX27), END4_GEOSL  (Q74FS7), END4_GEOSM  (C6DYE3), 
END4_GEOSW  (C5D4R0), END4_GEOTN  (A4IR02), END4_GLAP5  (B8F7D1), 
END4_HAEDU  (Q7VMC4), END4_HALH5  (Q9KD33), END4_HALHL  (A1WXM0), 
END4_HALOH  (B8CW79), END4_HERA2  (A9B5N7), END4_KLEP3  (B5XP51), 
END4_KLEP7  (A6TBP4), END4_LACP7  (A9KNS9), END4_LACPL  (Q88VR2), 
END4_LISIN  (Q92BR0), END4_LISMC  (C1KV96), END4_LISMF  (Q71ZM1), 
END4_LISMO  (Q8Y756), END4_LISW6  (A0AIQ1), END4_LYSSC  (B1HTF6), 
END4_MAGMM  (A0L901), END4_MALP2  (Q8EWT2), END4_MESH2  (Q601Y6), 
END4_MESH7  (Q4A8V0), END4_MESHJ  (Q4AAX4), END4_METST  (Q2NFM3), 
END4_MYCBO  (P63536), END4_MYCBP  (A1KGF0), END4_MYCBT  (C1AL03), 
END4_MYCCT  (Q2ST57), END4_MYCGA  (Q7NBA9), END4_MYCGE  (P47477), 
END4_MYCLB  (B8ZSC5), END4_MYCLE  (P30770), END4_MYCMM  (B2HSJ8), 
END4_MYCMS  (Q6MUC7), END4_MYCPN  (P75457), END4_MYCPU  (Q98PU8), 
END4_MYCS5  (Q4A6S5), END4_MYCTA  (A5U056), END4_MYCTO  (P9WQ12), 
END4_MYCTU  (P9WQ13), END4_MYCUA  (A0PM27), END4_NAUPA  (B9L9K0), 
END4_NITSB  (A6Q1P1), END4_NITV2  (Q72CQ9), END4_NITV4  (A1VEI5), 
END4_OCEIH  (Q8EPZ2), END4_OLEA2  (Q30YP7), END4_ONYPE  (Q6YQC1), 
END4_PARD8  (A6LB99), END4_PARUW  (Q6MED0), END4_PECAS  (Q6D3L8), 
END4_PECCP  (C6DEL1), END4_PELPB  (B4SE58), END4_PETMO  (A9BJ15), 
END4_PHOLL  (Q7N364), END4_PHOPR  (Q6LUP5), END4_PHOV8  (A6L330), 
END4_PROA2  (B4S3I3), END4_PROMH  (B4ETA5), END4_SALA4  (B5EYQ5), 
END4_SALAR  (A9MK49), END4_SALCH  (Q57MD6), END4_SALDC  (B5FNK8), 
END4_SALEP  (B5R173), END4_SALG2  (B5RC42), END4_SALHS  (B4TAM6), 
END4_SALNS  (B4SY37), END4_SALPA  (Q5PE50), END4_SALPB  (A9N6I5), 
END4_SALPC  (C0Q0T7), END4_SALPK  (B5BE34), END4_SALSV  (B4TNR0), 
END4_SALTI  (Q8Z593), END4_SALTY  (Q8ZNK6), END4_SERP5  (A8GGT5), 
END4_SHIB3  (B2TVT4), END4_SHIBS  (Q31YW6), END4_SHIDS  (Q32EQ7), 
END4_SHIF8  (Q0T2W5), END4_SHIFL  (Q83QW6), END4_SHISS  (Q3Z047), 
END4_SHOC1  (Q5WHC2), END4_STAA1  (A7X2V2), END4_STAA2  (A6U229), 
END4_STAA3  (Q2FGG6), END4_STAA8  (Q2FY16), END4_STAA9  (A5IT85), 
END4_STAAB  (Q2YT22), END4_STAAC  (Q5HFK3), END4_STAAE  (A6QHA0), 
END4_STAAM  (P63537), END4_STAAN  (P63538), END4_STAAR  (Q6GGE2), 
END4_STAAS  (Q6G909), END4_STAAT  (A8Z497), END4_STAAW  (P63539), 
END4_STACT  (B9DNM8), END4_STAEQ  (Q5HNZ1), END4_STAES  (Q8CP25), 
END4_STAHJ  (Q4L6Q7), END4_STAS1  (Q49Y00), END4_STRAW  (Q82AG6), 
END4_STRCO  (Q9S2N2), END4_SULDN  (Q30PH2), END4_SULNB  (A6QCI0), 
END4_THEAB  (B7IDS7), END4_THEAC  (Q9HJS3), END4_THEM4  (A6LMU8), 
END4_THEMA  (Q9WYJ7), END4_THEP1  (A5IK54), END4_THESQ  (B1L9C6), 
END4_THEVO  (Q97A09), END4_TOLAT  (C4LD49), END4_TRIL1  (B3E325), 
END4_UREPA  (Q9PQI5), END4_UREU1  (B5ZBB4), END4_VIBC1  (A7MS84), 
END4_VIBC3  (A5F5R6), END4_VIBCH  (Q9KPK7), END4_VIBCM  (C3LQD2), 
END4_VIBPA  (Q87SC6), END4_VIBVU  (Q8DEP6), END4_VIBVY  (Q7MNR1), 
END4_WOLSU  (Q7M8B4), END4_YERE8  (A1JLX8), END4_YERP3  (A7FK62), 
END4_YERPA  (Q1C982), END4_YERPB  (B2K9J1), END4_YERPE  (Q8ZGJ1), 
END4_YERPG  (A9R4S1), END4_YERPN  (Q1CG79), END4_YERPP  (A4TNA4), 
END4_YERPS  (Q66CR5), END4_YERPY  (B1JRM5)
» more

UniProtKB/Swiss-Prot
False negative sequences
44 sequences

APE_ASFB7   (Q65202), APE_ASFK5   (P0C9C8), APE_ASFM2   (Q65246), 
APE_ASFP4   (P0C9C6), APE_ASFWA   (P0C9C7), END4_AKKM8  (B2UQE3), 
END4_ALKOO  (A8ML82), END4_BIFLD  (B3DS13), END4_BIFLO  (Q8G689), 
END4_BIFLS  (B7GRN1), END4_CAMFF  (A0RRG4), END4_CARHZ  (Q3ABA7), 
END4_CENSY  (A0RYW7), END4_CLOB8  (A6LQV9), END4_CLOBA  (B2V158), 
END4_CLOBB  (B2TL64), END4_CLOD6  (Q189A4), END4_CROS8  (A7MLL2), 
END4_FINM2  (B0S196), END4_HALMA  (Q5V0S8), END4_HALS3  (B0R2U6), 
END4_HALSA  (Q9HSK7), END4_HALWD  (Q18KA6), END4_HELMI  (B0TD39), 
END4_LATSS  (Q38XB2), END4_MESFL  (Q6F1D3), END4_META1  (B3PMH1), 
END4_METLZ  (A2SPZ6), END4_METMJ  (A3CT71), END4_METPE  (B8GKX5), 
END4_MIMIV  (Q5UPY4), END4_MOOTA  (Q2RJF1), END4_MYCAP  (A5IYT8), 
END4_MYCM1  (Q6KH96), END4_NATPD  (Q3IMK8), END4_NATTJ  (B2A499), 
END4_NITMS  (A9A555), END4_PEDPA  (Q03F56), END4_PERMH  (C0QRI1), 
END4_SOLUE  (Q01TU5), END4_SULSY  (B2V7A4), END4_SYMTH  (Q67S99), 
END4_THENN  (B9KBS2), END4_THET2  (Q72KH8)
» more

UniProtKB/Swiss-Prot
'Partial' sequences
2 sequences

END4_THENE  (O86954), END4_YEREN  (P42691)

		
UniProtKB/Swiss-Prot
False positive sequences
5 sequences

EZH1_BOVIN  (A7E2Z2), EZH1_HUMAN  (Q92800), EZH1_MOUSE  (P70351), 
EZH1_PONAB  (Q5RDS6), GCP4_DROME  (Q9VKU7)
» more

PDB
[Detailed view]
12 PDB

1QTW; 1QUM; 1XP3; 2NQH; 2NQJ; 2X7V; 2X7W; 3AAL; 4HNO; 5ZHZ; 8AXY; 8EDD