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PROSITE entry PS00743


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00743
Entry name [info] BETA_LACTAMASE_B_1
Accession [info] PS00743
Entry type [info] PATTERN
Date [info] 01-DEC-1992 CREATED;
01-APR-2003 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00606

Name and characterization of the entry

Description [info] Beta-lactamases class B signature 1.
Pattern [info] 
[LI]-x-[STN]-[HN]-x-H-[GSTAD]-D-x(2)-G-[GP]-x(7,8)-[GS].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 27 in 27 different sequences
Number of true positive hits 23 in 23 different sequences
Number of 'unknown' hits 0
Number of false positive hits 4 in 4 different sequences
Number of false negative sequences 3
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 85.19 %
Recall (true positives / (true positives + false negatives)) 88.46 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] zinc at position 4
Site [info] zinc at position 6
Site [info] zinc at position 8
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 23 sequences 

BLA1_STEMA  (P52700), BLA2_BAC17  (P10425), BLA2_BACCE  (P04190), 

BLAB1_ELIME (O08498), BLAB2_ELIME (Q9RB01), BLAB3_ELIME (Q9K303), 
BLAB4_ELIME (Q9XBN7), BLAB5_ELIME (Q9KJA9), BLAB6_ELIME (Q9KJB0), 
BLAB7_ELIME (Q9KJA8), BLAB8_ELIME (Q9KJA7), BLAB_AERHY  (P26918), 
BLAB_BACCE  (P14488), BLAB_BACFG  (P25910), BLAB_PSEAI  (Q7WYA8), 
BLBI1_SERMA (P52699), BLBV7_PSEAI (Q840P9), NSCB_ARTBC  (D4AWH0), 
NSCB_ARTOC  (C5FM60), NSCB_TRIEC  (F2PWS8), NSCB_TRIRC  (F2T0M3), 
NSCB_TRIT1  (F2S702), NSCB_TRIVH  (D4CZZ5)
» more

UniProtKB/Swiss-Prot
False negative sequences		 3 sequences 

BLAN1_KLEPN (C7C422), DNHA_NOCS1  (A0A096ZEC9), DNHB_NOCS1  (A0A096ZED0)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			4 sequences
			


			
GLO2M_ARATH (O24495), GLO2_ANADE  (Q2IJC6), GLO2_METCA  (Q60BX0), 

			
GLO2_SYNS3  (Q0I8S8)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			123 PDB
			


			1A7T; 1A8T; 1BC2; 1BMC; 1BVT; 1DD6; 1DXK; 1HLK; 1KR3; 1M2X; 1MQO; 1SML; 
			
				1VGN; 1X8G; 1X8H; 1X8I; 1ZNB; 2AIO; 2BC2; 2BFK; 2BFL; 2BFZ; 2BG2; 2BG6; 
				2BG7; 2BG8; 2BGA; 2BMI; 2DOO; 2FM6; 2FU6; 2FU7; 2FU8; 2FU9; 2GFJ; 2GFK; 
				2GKL; 2H6A; 2HB9; 2M5C; 2M5D; 2NXA; 2NYP; 2NZE; 2NZF; 2QDS; 2QDT; 2Y87; 
				2Y8A; 2Y8B; 2ZNB; 3BC2; 3F9O; 3FAI; 3FCZ; 3I0V; 3I11; 3I13; 3I14; 3I15; 
				3IOF; 3IOG; 3KNR; 3KNS; 3SW3; 3T9M; 3ZNB; 4C09; 4C1C; 4C1F; 4C1G; 4C1H; 
				4D1T; 4D1V; 4D1W; 4NQ4; 4NQ5; 4NQ6; 4TYT; 4ZNB; 5DPX; 5EV6; 5EV8; 5EVB; 
				5EVD; 5EVK; 5EWA; 5FQA; 5FQB; 5HH4; 5HH5; 5HH6; 5JMX; 5W8W; 5Y5B; 6DJA; 
				6EUM; 6EWE; 6F2N; 6JED; 6JKA; 6LBL; 6R73; 6R79; 6RZR; 6RZS; 6S0H; 6YI4; 
				6ZYR; 6ZYS; 7A63; 7AFZ; 7BJ8; 7DTM; 7O0O; 7ZO2; 7ZO3; 7ZO4; 7ZO5; 7ZO6; 
				7ZO7; 8HXE; 8Z5L
			
			

			» more