PROSITE entry PS00754

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General information about the entry

Entry name [info]	NA_NEUROTRAN_SYMP_2
Accession [info]	PS00754
Entry type [info]	PATTERN
Date [info]	01-DEC-1992 CREATED; 01-DEC-2004 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00533

Name and characterization of the entry

Description [info]	Sodium:neurotransmitter symporter family signature 2.
Pattern [info]	[YF]-[LIVMFY]-x(2)-[SC]-[LIVMFY]-[STQV]-x(2)-[LVI]-P-W-x(2)-C-x(3,4)- [NWDS]-[GSTERHAK].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.

Total number of hits	82 in 82 different sequences
Number of true positive hits	82 in 82 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	15
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	84.54 %

Comments [info]

Taxonomic range [info]	Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Site [info]	disulfide(?) at position 12
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

82 sequences

DAT_DROME   (Q7K4Y6), NAAT1_DROER (B3NV41), NAAT1_DROME (Q9W4C5),

NAAT1_DROMO (B4L7U0), NAAT1_DROSI (B4R4T6), NAAT1_DROWI (B4NDL8), 
NAAT1_DROYA (B4PZQ4), NTDO_CAEEL  (Q03614), S620A_MOUSE (Q8VDB9), 
S620B_MOUSE (O88575), S6A11_HUMAN (P48066), S6A11_MOUSE (P31650), 
S6A11_RAT   (P31647), S6A12_CANLF (P27799), S6A12_HUMAN (P48065), 
S6A12_MOUSE (P31651), S6A12_RABIT (P48055), S6A12_RAT   (P48056), 
S6A13_BOVIN (A5PJX7), S6A13_HUMAN (Q9NSD5), S6A13_MACFA (Q2PG55), 
S6A13_MOUSE (P31649), S6A13_RAT   (P31646), S6A14_HUMAN (Q9UN76), 
S6A14_MOUSE (Q9JMA9), S6A15_BOVIN (Q9XS59), S6A15_HUMAN (Q9H2J7), 
S6A15_MOUSE (Q8BG16), S6A15_PONAB (Q5R9C2), S6A15_RAT   (Q08469), 
S6A16_HUMAN (Q9GZN6), S6A17_BOVIN (Q28001), S6A17_HUMAN (Q9H1V8), 
S6A17_MOUSE (Q8BJI1), S6A17_RAT   (P31662), S6A18_HUMAN (Q96N87), 
S6A18_MOUSE (O88576), S6A18_RAT   (Q62687), S6A20_HUMAN (Q9NP91), 
S6A20_RAT   (Q64093), SC6A1_HUMAN (P30531), SC6A1_MOUSE (P31648), 
SC6A1_MUSCO (P48057), SC6A1_RAT   (P23978), SC6A2_BOVIN (P51143), 
SC6A2_HUMAN (P23975), SC6A2_MOUSE (O55192), SC6A3_BOVIN (P27922), 
SC6A3_HUMAN (Q01959), SC6A3_MACFA (Q9GJT6), SC6A3_MOUSE (Q61327), 
SC6A3_RAT   (P23977), SC6A4_BOVIN (Q9XT49), SC6A4_CAVPO (O35899), 
SC6A4_DROME (P51905), SC6A4_HUMAN (P31645), SC6A4_MACMU (Q9MYX0), 
SC6A4_MOUSE (Q60857), SC6A4_RAT   (P31652), SC6A5_HUMAN (Q9Y345), 
SC6A5_MOUSE (Q761V0), SC6A5_RAT   (P58295), SC6A5_XENLA (A7Y2X0), 
SC6A6_BOVIN (Q9MZ34), SC6A6_CANLF (Q00589), SC6A6_HUMAN (P31641), 
SC6A6_MOUSE (O35316), SC6A6_RAT   (P31643), SC6A7_HUMAN (Q99884), 
SC6A7_MOUSE (Q6PGE7), SC6A7_RAT   (P28573), SC6A8_BOVIN (O18875), 
SC6A8_HUMAN (P48029), SC6A8_MOUSE (Q8VBW1), SC6A8_RABIT (P31661), 
SC6A8_RAT   (P28570), SC6A8_TORMA (Q91502), SC6A9_BOVIN (Q28039), 
SC6A9_HUMAN (P48067), SC6A9_MOUSE (P28571), SC6A9_RAT   (P28572), 
SNF6_CAEEL  (O76689)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

15 sequences

BDGED_DROME (Q0E961), INE_DROME   (Q9VR07), NAAT1_DROAN (B3MRS1),

NAAT1_DROGR (B4JMC1), NAAT1_DROPE (B4GVM9), NAAT1_DROPS (Q29GB8), 
NAAT1_DROVI (B4MEG2), SC6A9_XENLA (A7Y2W8), SNF3_CAEEL  (G5EBN9), 
SNF5_CAEEL  (G5EBM5), Y1319_METJA (Q58715), Y1690_HAEIN (P45320), 
Y736_HAEIN  (P44849), YHDH_BACSU  (O07577), YOCR_BACSU  (O34383)

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PDB
[Detailed view]

84 PDB

4M48; 4XNU; 4XNX; 4XP1; 4XP4; 4XP5; 4XP6; 4XP9; 4XPA; 4XPB; 4XPF; 4XPG; 4XPH; 4XPT; 5I6X; 5I6Z; 5I71; 5I73; 5I74; 5I75; 6AWN; 6AWO; 6AWP; 6AWQ; 6DZV; 6DZW; 6DZY; 6DZZ; 6M0F; 6M0Z; 6M2R; 6M38; 6M3Z; 6M47; 6VRH; 6VRK; 6VRL; 6W2B; 6W2C; 6ZBV; 6ZPL; 7LI6; 7LI7; 7LI8; 7LI9; 7LIA; 7LWD; 7MGW; 7SK2; 7TXT; 7WGD; 7WGT; 7WLW; 7Y75; 7Y76; 7Y7V; 7Y7W; 7Y7Y; 7Y7Z; 8GNK; 8HFE; 8HFF; 8HFG; 8HFI; 8HFL; 8I91; 8P2W; 8P2X; 8P2Y; 8P2Z; 8P30; 8P31; 8WFI; 8WFJ; 8WFK; 8WFL; 8Y8Z; 8Y90; 8Y91; 8Y92; 8Y93; 8Y94; 8Y95; 8YR2
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