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PROSITE entry PS00754


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PURL: https://purl.expasy.org/prosite/signature/PS00754

Direct ScanProsite submission
General information about the entry

Entry name [info] NA_NEUROTRAN_SYMP_2
Accession [info] PS00754
Entry type [info] PATTERN
Date [info] 01-DEC-1992 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00533

Name and characterization of the entry

Description [info] Sodium:neurotransmitter symporter family signature 2.
Pattern [info] 
[YF]-[LIVMFY]-x(2)-[SC]-[LIVMFY]-[STQV]-x(2)-[LVI]-P-W-x(2)-C-x(3,4)-
[NWDS]-[GSTERHAK].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 82 in 82 different sequences
Number of true positive hits 82 in 82 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 15
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 84.54 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] disulfide(?) at position 12
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 82 sequences 

DAT_DROME   (Q7K4Y6), NAAT1_DROER (B3NV41), NAAT1_DROME (Q9W4C5), 

NAAT1_DROMO (B4L7U0), NAAT1_DROSI (B4R4T6), NAAT1_DROWI (B4NDL8), 
NAAT1_DROYA (B4PZQ4), NTDO_CAEEL  (Q03614), S620A_MOUSE (Q8VDB9), 
S620B_MOUSE (O88575), S6A11_HUMAN (P48066), S6A11_MOUSE (P31650), 
S6A11_RAT   (P31647), S6A12_CANLF (P27799), S6A12_HUMAN (P48065), 
S6A12_MOUSE (P31651), S6A12_RABIT (P48055), S6A12_RAT   (P48056), 
S6A13_BOVIN (A5PJX7), S6A13_HUMAN (Q9NSD5), S6A13_MACFA (Q2PG55), 
S6A13_MOUSE (P31649), S6A13_RAT   (P31646), S6A14_HUMAN (Q9UN76), 
S6A14_MOUSE (Q9JMA9), S6A15_BOVIN (Q9XS59), S6A15_HUMAN (Q9H2J7), 
S6A15_MOUSE (Q8BG16), S6A15_PONAB (Q5R9C2), S6A15_RAT   (Q08469), 
S6A16_HUMAN (Q9GZN6), S6A17_BOVIN (Q28001), S6A17_HUMAN (Q9H1V8), 
S6A17_MOUSE (Q8BJI1), S6A17_RAT   (P31662), S6A18_HUMAN (Q96N87), 
S6A18_MOUSE (O88576), S6A18_RAT   (Q62687), S6A20_HUMAN (Q9NP91), 
S6A20_RAT   (Q64093), SC6A1_HUMAN (P30531), SC6A1_MOUSE (P31648), 
SC6A1_MUSCO (P48057), SC6A1_RAT   (P23978), SC6A2_BOVIN (P51143), 
SC6A2_HUMAN (P23975), SC6A2_MOUSE (O55192), SC6A3_BOVIN (P27922), 
SC6A3_HUMAN (Q01959), SC6A3_MACFA (Q9GJT6), SC6A3_MOUSE (Q61327), 
SC6A3_RAT   (P23977), SC6A4_BOVIN (Q9XT49), SC6A4_CAVPO (O35899), 
SC6A4_DROME (P51905), SC6A4_HUMAN (P31645), SC6A4_MACMU (Q9MYX0), 
SC6A4_MOUSE (Q60857), SC6A4_RAT   (P31652), SC6A5_HUMAN (Q9Y345), 
SC6A5_MOUSE (Q761V0), SC6A5_RAT   (P58295), SC6A5_XENLA (A7Y2X0), 
SC6A6_BOVIN (Q9MZ34), SC6A6_CANLF (Q00589), SC6A6_HUMAN (P31641), 
SC6A6_MOUSE (O35316), SC6A6_RAT   (P31643), SC6A7_HUMAN (Q99884), 
SC6A7_MOUSE (Q6PGE7), SC6A7_RAT   (P28573), SC6A8_BOVIN (O18875), 
SC6A8_HUMAN (P48029), SC6A8_MOUSE (Q8VBW1), SC6A8_RABIT (P31661), 
SC6A8_RAT   (P28570), SC6A8_TORMA (Q91502), SC6A9_BOVIN (Q28039), 
SC6A9_HUMAN (P48067), SC6A9_MOUSE (P28571), SC6A9_RAT   (P28572), 
SNF6_CAEEL  (O76689)
» more

UniProtKB/Swiss-Prot
False negative sequences		 15 sequences 

BDGED_DROME (Q0E961), INE_DROME   (Q9VR07), NAAT1_DROAN (B3MRS1), 

NAAT1_DROGR (B4JMC1), NAAT1_DROPE (B4GVM9), NAAT1_DROPS (Q29GB8), 
NAAT1_DROVI (B4MEG2), SC6A9_XENLA (A7Y2W8), SNF3_CAEEL  (G5EBN9), 
SNF5_CAEEL  (G5EBM5), Y1319_METJA (Q58715), Y1690_HAEIN (P45320), 
Y736_HAEIN  (P44849), YHDH_BACSU  (O07577), YOCR_BACSU  (O34383)
» more

PDB
[Detailed view]		 115 PDB

pdb_00004m48; pdb_00004xnu; pdb_00004xnx; pdb_00004xp1; pdb_00004xp4; pdb_00004xp5; pdb_00004xp6; pdb_00004xp9; pdb_00004xpa; pdb_00004xpb; pdb_00004xpf; pdb_00004xpg; pdb_00004xph; pdb_00004xpt; pdb_00005i6x; pdb_00005i6z; pdb_00005i71; pdb_00005i73; pdb_00005i74; pdb_00005i75; pdb_00006awn; pdb_00006awo; pdb_00006awp; pdb_00006awq; pdb_00006dzv; pdb_00006dzw; pdb_00006dzy; pdb_00006dzz; pdb_00006m0f; pdb_00006m0z; pdb_00006m2r; pdb_00006m38; pdb_00006m3z; pdb_00006m47; pdb_00006vrh; pdb_00006vrk; pdb_00006vrl; pdb_00006w2b; pdb_00006w2c; pdb_00006zbv; pdb_00006zpl; pdb_00007li6; pdb_00007li7; pdb_00007li8; pdb_00007li9; pdb_00007lia; pdb_00007lwd; pdb_00007mgw; pdb_00007sk2; pdb_00007txt; pdb_00007wgd; pdb_00007wgt; pdb_00007wlw; pdb_00007y75; pdb_00007y76; pdb_00007y7v; pdb_00007y7w; pdb_00007y7y; pdb_00007y7z; pdb_00008gnk; pdb_00008hfe; pdb_00008hff; pdb_00008hfg; pdb_00008hfi; pdb_00008hfl; pdb_00008i3v; pdb_00008i91; pdb_00008p2w; pdb_00008p2x; pdb_00008p2y; pdb_00008p2z; pdb_00008p30; pdb_00008p31; pdb_00008vby; pdb_00008wfi; pdb_00008wfj; pdb_00008wfk; pdb_00008wfl; pdb_00008wgr; pdb_00008wgx; pdb_00008wm3; pdb_00008wtu; pdb_00008wtv; pdb_00008wtw; pdb_00008wtx; pdb_00008wty; pdb_00008xb2; pdb_00008xb3; pdb_00008xb4; pdb_00008y2c; pdb_00008y2d; pdb_00008y2e; pdb_00008y2f; pdb_00008y2g; pdb_00008y8z; pdb_00008y90; pdb_00008y91; pdb_00008y92; pdb_00008y93; pdb_00008y94; pdb_00008y95; pdb_00008yr2; pdb_00008z1l; pdb_00008zoy; pdb_00008zp1; pdb_00008zp2; pdb_00008zpb; pdb_00009eo4; pdb_00009euo; pdb_00009eup; pdb_00009j8b; pdb_00009j8c; pdb_00009j8d; pdb_00009k7b; pdb_00009k7n
» more