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Entry: PS00760

General information about the entry

Entry name [info] SPASE_I_2
Accession [info] PS00760
Entry type [info] PATTERN
Date [info] 01-DEC-1992 CREATED;
01-DEC-2004 DATA UPDATE;
02-JUN-2021 INFO UPDATE.
PROSITE Doc. [info] PDOC00418
Associated ProRule [info] PRU10098

Name and characterization of the entry

Description [info] Signal peptidases I lysine active site.
Pattern [info] 
K-R-[LIVMSTA](2)-[GA]-x-[PG]-G-[DEQ]-x-[LIVM]-x-[LIVMFY].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2021_03 which contains 565'254 sequence entries.


Total number of hits 46 in 46 different sequences
Number of true positive hits 44 in 44 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 22
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 95.65 %
Recall (true positives / (true positives + false negatives)) 66.67 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 44 sequences 

IMP1_SCHPO  (O74800    ), IMP1_YEAST  (P28627    ), LEP1_BACAM  (P41026    ), 

LEP1_SYNY3  (P72660    ), LEP2_BACAM  (P41025    ), LEP2_SYNY3  (P73157    ), 
LEPP_BACNA  (P37943    ), LEPQ_BACNA  (Q57350    ), LEPS_BACSU  (P28628    ), 
LEPT_BACSU  (P71013    ), LEPU_BACSU  (P42959    ), LEPV_BACSU  (O07560    ), 
LEP_AQUAE   (O67088    ), LEP_BACCL   (P41027    ), LEP_BACLI   (P42668    ), 
LEP_BUCAI   (P57347    ), LEP_BUCAP   (Q8K9R0    ), LEP_BUCBP   (Q89AM6    ), 
LEP_ECOLI   (P00803    ), LEP_HAEIN   (P44454    ), LEP_PHOLA   (Q51876    ), 
LEP_PSEAE   (Q9I5G7    ), LEP_PSEFL   (P26844    ), LEP_RICAH   (A8GM78    ), 
LEP_RICB8   (A8GYE1    ), LEP_RICBR   (Q1RHA1    ), LEP_RICCK   (A8EXI2    ), 
LEP_RICCN   (Q92JB1    ), LEP_RICFE   (Q4UKA7    ), LEP_RICM5   (A8F0M1    ), 
LEP_RICPR   (Q9ZE32    ), LEP_RICRS   (A8GQT7    ), LEP_RICTY   (Q8L2J7    ), 
LEP_SALTI   (P0A1W3    ), LEP_SALTY   (P0A1W2    ), LEP_STAAC   (Q5HHB9    ), 
LEP_STAAM   (P0A067    ), LEP_STAAN   (P0A068    ), LEP_STAAR   (Q6GIC3    ), 
LEP_STAAS   (Q6GAW1    ), LEP_STAAU   (P0A070    ), LEP_STAAW   (P0A069    ), 
LEP_STRPN   (O07344    ), LEP_STRR6   (P59662    )
» more

UniProtKB/Swiss-Prot
False negative sequences		 22 sequences 

IMP1L_HUMAN (Q96LU5    ), IMP1L_MOUSE (Q9CQU8    ), IMP1L_XENTR (Q28I39    ), 

IMP2L_BOVIN (Q2KI92    ), IMP2L_DANRE (Q6AZD4    ), IMP2L_HUMAN (Q96T52    ), 
IMP2L_MOUSE (Q8BPT6    ), IMP2L_SCHPO (Q9UST2    ), IMP2L_XENLA (Q5PQ63    ), 
IMP2_YEAST  (P46972    ), LEPH_STAAC  (Q5HHC0    ), LEPH_STAAM  (P0A063    ), 
LEPH_STAAN  (P0A064    ), LEPH_STAAR  (Q6GIC4    ), LEPH_STAAS  (Q6GAW2    ), 
LEPH_STAAU  (P0A066    ), LEPH_STAAW  (P0A065    ), LEP_HELPJ   (Q9ZLQ5    ), 
LEP_HELPY   (O25300    ), LEP_MYCLE   (O33021    ), LEP_MYCTO   (P9WKA0    ), 
LEP_MYCTU   (P9WKA1    )
» more

UniProtKB/Swiss-Prot
False positive sequences		 2 sequences 

RL18_THEAN  (Q4UFD5    ), RL18_THEPA  (Q4N438    )


				
	

	

		PDB
[Detailed view]		
		
			10 PDB
			


			1B12; 1KN9; 1T7D; 3IIQ; 3S04; 4WVG; 4WVH; 4WVI; 4WVJ; 6B88
				
	





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