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PROSITE entry PS00761


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General information about the entry

Entry name [info] SPASE_I_3
Accession [info] PS00761
Entry type [info] PATTERN
Date [info] 01-DEC-1992 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00418

Name and characterization of the entry

Description [info] Signal peptidases I signature 3.
Pattern [info]
[LIVMFYW](2)-{NLPA}-{T}-G-D-[NH]-{PIEW}-x(2)-[SND]-x(2)-[SG].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 112 in 112 different sequences
Number of true positive hits 90 in 90 different sequences
Number of 'unknown' hits 0
Number of false positive hits 22 in 22 different sequences
Number of false negative sequences 61
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 80.36 %
Recall (true positives / (true positives + false negatives)) 59.60 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
90 sequences

IMP1A_ARATH (Q6NLT8), IMP2L_BOVIN (Q2KI92), IMP2L_DANRE (Q6AZD4), 
IMP2L_HUMAN (Q96T52), IMP2L_MOUSE (Q8BPT6), IMP2L_XENLA (Q5PQ63), 
IMP2_YEAST  (P46972), LEP1_BACAM  (P41026), LEP1_SYNY3  (P72660), 
LEP2_BACAM  (P41025), LEP2_SYNY3  (P73157), LEPP_BACNA  (P37943), 
LEPQ_BACNA  (Q57350), LEPS_BACSU  (P28628), LEPT_BACSU  (P71013), 
LEPU_BACSU  (P42959), LEPV_BACSU  (O07560), LEP_AQUAE   (O67088), 
LEP_BACCL   (P41027), LEP_BACLI   (P42668), LEP_BUCAI   (P57347), 
LEP_BUCAP   (Q8K9R0), LEP_BUCBP   (Q89AM6), LEP_ECOLI   (P00803), 
LEP_HAEIN   (P44454), LEP_HELPJ   (Q9ZLQ5), LEP_HELPY   (O25300), 
LEP_MYCLE   (O33021), LEP_MYCTO   (P9WKA0), LEP_MYCTU   (P9WKA1), 
LEP_PHOLA   (Q51876), LEP_PSEAE   (Q9I5G7), LEP_PSEFL   (P26844), 
LEP_RICAH   (A8GM78), LEP_RICB8   (A8GYE1), LEP_RICBR   (Q1RHA1), 
LEP_RICCK   (A8EXI2), LEP_RICCN   (Q92JB1), LEP_RICFE   (Q4UKA7), 
LEP_RICM5   (A8F0M1), LEP_RICPR   (Q9ZE32), LEP_RICRS   (A8GQT7), 
LEP_RICTY   (Q8L2J7), LEP_SALTI   (P0A1W3), LEP_SALTY   (P0A1W2), 
LEP_STAAC   (Q5HHB9), LEP_STAAM   (P0A067), LEP_STAAN   (P0A068), 
LEP_STAAR   (Q6GIC3), LEP_STAAS   (Q6GAW1), LEP_STAAU   (P0A070), 
LEP_STAAW   (P0A069), PLSP1_ARATH (Q8H0W1), SC11A_BOVIN (P67810), 
SC11A_CANLF (P67811), SC11A_HUMAN (P67812), SC11A_MOUSE (Q9R0P6), 
SC11A_PONAB (Q5R9C7), SC11A_RAT   (P42667), SC11B_HUMAN (P0C7V7), 
SC11C_CANLF (P13679), SC11C_HUMAN (Q9BY50), SC11C_MOUSE (Q9D8V7), 
SC11C_PONAB (Q5RC30), SC11C_RAT   (Q9WTR7), SEC11_CANAL (Q5A869), 
SEC11_CANAW (C4YNJ0), SEC11_CANDC (B9WKT4), SEC11_CANTT (C5M4J6), 
SEC11_CLAL4 (C4Y3D4), SEC11_DEBHA (Q6BP15), SEC11_KOMPG (C4QXP7), 
SEC11_LODEL (A5DS09), SEC11_PICGU (A5DIZ8), SEC11_PICST (A3LXS1), 
SEC11_PLAF7 (Q8IE14), SEC11_SCHCM (D8Q7Q5), SEC11_YARLI (Q6CAG9), 
SEC11_YEAS1 (B3LTI7), SEC11_YEAS2 (C7GLT4), SEC11_YEAS7 (A6ZVU2), 
SEC11_YEAS8 (C8ZAS4), SEC11_YEASA (E7KDY6), SEC11_YEASB (E7Q587), 
SEC11_YEASL (E7KQ01), SEC11_YEAST (P15367), SEC11_YEASV (E7LVX4), 
SEC11_YEASZ (E7QG89), TPP1_ARATH  (O04348), TPP2_ARATH  (Q9M9Z2)
» more

UniProtKB/Swiss-Prot
False negative sequences
61 sequences

IMP1L_HUMAN (Q96LU5), IMP1L_MOUSE (Q9CQU8), IMP1L_XENTR (Q28I39), 
IMP1_YEAST  (P28627), IMP2L_SCHPO (Q9UST2), LEPH_STAAC  (Q5HHC0), 
LEPH_STAAM  (P0A063), LEPH_STAAN  (P0A064), LEPH_STAAR  (Q6GIC4), 
LEPH_STAAS  (Q6GAW2), LEPH_STAAU  (P0A066), LEPH_STAAW  (P0A065), 
LEP_STRPN   (O07344), LEP_STRR6   (P59662), SEC11_AJEC8 (F0UDD2), 
SEC11_AJECG (C0NKT8), SEC11_AJECH (C6HB29), SEC11_AJECN (A6QX24), 
SEC11_AJEDR (C5G8L5), SEC11_ARTBC (D4ALL0), SEC11_ARTGP (E4V4X0), 
SEC11_ARTOC (C5FQ45), SEC11_ASPCL (A1CL29), SEC11_ASPFC (B0XWT3), 
SEC11_ASPFU (Q4WYF4), SEC11_ASPOR (Q2UBW3), SEC11_ASPTN (Q0CQC5), 
SEC11_BLAGS (C5JJG5), SEC11_CHAGB (Q2H1P3), SEC11_COCP7 (C5PA33), 
SEC11_COCPS (E9CXH2), SEC11_COLGM (E3QXY4), SEC11_EMENI (Q5B8K4), 
SEC11_EREGS (Q759W4), SEC11_FUSV7 (C7ZHK5), SEC11_GROCL (F0XJH4), 
SEC11_KLULA (Q6CMR5), SEC11_LACBS (B0D4L0), SEC11_LACTC (C5DDH1), 
SEC11_LEPMJ (E5A8D2), SEC11_METAQ (E9E796), SEC11_METRA (E9F8V9), 
SEC11_NEOFI (A1D6D8), SEC11_NEUCR (Q7RY44), SEC11_OGAPD (E7R7C4), 
SEC11_PARBA (C1GU90), SEC11_PARBD (C1FYD2), SEC11_PARBP (C0S3S0), 
SEC11_PENRW (B6HC89), SEC11_PODAN (B2B3T2), SEC11_PYRO7 (A4RGA1), 
SEC11_PYRTR (B2WEL2), SEC11_PYRTT (E3RR70), SEC11_SCLS1 (A7E716), 
SEC11_TALMQ (B6Q5G0), SEC11_TALSN (B8M5K5), SEC11_TRIVH (D4D5I1), 
SEC11_TUBMM (D5GNC3), SEC11_UNCRE (C4JYM4), SEC11_VERA1 (C9S8G0), 
SEC11_ZYGRC (C5E3W1)
» more

UniProtKB/Swiss-Prot
False positive sequences
22 sequences

ACSA_PASMU  (Q9CMW1), ADPRL_MIMIV (Q5UQP4), C508D_DICDI (Q1ZXA4), 
CBIK_SALTY  (Q05592), CCDC9_MOUSE (Q8VC31), CT54_CONVE  (Q9BPF7), 
DGOK_ECOLI  (P31459), GLNA1_DICDI (Q86B00), HLDE_DICNV  (A5EWS4), 
MYO7B_MOUSE (Q99MZ6), NACA_DICDI  (Q54U07), OADC_PARXL  (Q13Q00), 
PILR3_ARATH (O65679), PUM8_ARATH  (Q9LM20), PURT_ACIAD  (Q6FAM6), 
RECA_IDILO  (Q5QUB8), SPT_CAUVN   (A0A0H3C7E9), SYR_OCEIH   (Q8EM45), 
TCPH_PLAF7  (O77323), THAL_ARATH  (Q8L3P4), UBP15_ORYSJ (Q0E2F9), 
Y309_MYCGE  (P47551)
» more

PDB
[Detailed view]
12 PDB

1B12; 1KN9; 1T7D; 3IIQ; 3S04; 4WVG; 4WVH; 4WVI; 4WVJ; 6B88; 7P2P; 7P2Q