PROSITE logo
Black ribbon
We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS00763


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
PURL: https://purl.expasy.org/prosite/signature/PS00763

Direct ScanProsite submission
General information about the entry

Entry name [info] GLUTATHIONE_PEROXID_2
Accession [info] PS00763
Entry type [info] PATTERN
Date [info] 01-DEC-1992 CREATED;
01-NOV-1997 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00396

Name and characterization of the entry

Description [info] Glutathione peroxidases signature 2.
Pattern [info]
[LIV]-[AGD]-F-P-[CS]-[NG]-Q-F.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 105 in 105 different sequences
Number of true positive hits 105 in 105 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 7
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 93.75 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
105 sequences

BSAA_BACSU  (P52035), BSAA_HALH5  (Q9Z9N7), BSAA_STAAC  (Q5HGC7), 
BSAA_STAAM  (P64290), BSAA_STAAN  (P99097), BSAA_STAAR  (Q6GHD0), 
BSAA_STAAS  (Q6G9Q8), BSAA_STAAW  (P64291), BSAA_STAES  (Q8CSR9), 
BTUE_ECOLI  (P06610), GPO_LACLA   (Q9CFV1), GPO_LACLM   (O32770), 
GPX1_ARATH  (P52032), GPX1_BOVIN  (P00435), GPX1_CAEEL  (O02621), 
GPX1_CHLRE  (P83564), GPX1_HELAN  (O23970), GPX1_HUMAN  (P07203), 
GPX1_HYLLA  (Q4AEI2), GPX1_MACFU  (Q865R2), GPX1_MOUSE  (P11352), 
GPX1_PANTR  (Q0EFA0), GPX1_PEA(O24296), GPX1_PIG(Q8MJ14), 
GPX1_PONPY  (Q4AEI3), GPX1_RABIT  (P11909), GPX1_RAT(P04041), 
GPX1_SCHMA  (Q00277), GPX1_SCHPO  (O59858), GPX1_SYNY3  (P74250), 
GPX1_YEAST  (P36014), GPX2_ARATH  (O04922), GPX2_CAEEL  (O62327), 
GPX2_HUMAN  (P18283), GPX2_HYLLA  (Q4AEH9), GPX2_MACFU  (Q4AEH8), 
GPX2_MOUSE  (Q9JHC0), GPX2_PONPY  (Q4AEI0), GPX2_RAT(P83645), 
GPX2_SAPAP  (Q4AEH7), GPX2_YEAST  (P38143), GPX3_ARATH  (O22850), 
GPX3_BOVIN  (P37141), GPX3_CAEEL  (Q95003), GPX3_CANAL  (Q59WD3), 
GPX3_HUMAN  (P22352), GPX3_HYLLA  (Q4AEH5), GPX3_MACFU  (Q4AEH4), 
GPX3_MOUSE  (P46412), GPX3_PONPY  (Q5RFG3), GPX3_RAT(P23764), 
GPX3_SAPAP  (Q4AEH3), GPX3_YEAST  (P40581), GPX4_ARATH  (Q8L910), 
GPX4_BOVIN  (Q9N2J2), GPX4_CALJA  (Q32QL6), GPX4_CITSI  (Q06652), 
GPX4_GOSHI  (O49069), GPX4_HELAN  (O23968), GPX4_HUMAN  (P36969), 
GPX4_HYLLA  (Q4AEH1), GPX4_MACFU  (Q4AEH0), GPX4_MESCR  (Q9LEF0), 
GPX4_MOUSE  (O70325), GPX4_NICSY  (P30708), GPX4_PIG(P36968), 
GPX4_PINPS  (P81087), GPX4_PONPY  (Q4AEH2), GPX4_RAT(P36970), 
GPX4_SAPAP  (Q4AEG9), GPX4_SOLLC  (O24031), GPX4_SPIOL  (O23814), 
GPX4_TOBAC  (Q9FXS3), GPX5_ARATH  (Q9LYB4), GPX5_CANLF  (O46607), 
GPX5_CHLRE  (O22448), GPX5_HUMAN  (O75715), GPX5_MACFA  (P28714), 
GPX5_MOUSE  (P21765), GPX5_PIG(O18994), GPX5_RAT(P30710), 
GPX6_ARATH  (O48646), GPX6_HUMAN  (P59796), GPX6_MOUSE  (Q91WR8), 
GPX6_RAT(Q64625), GPX7_ARATH  (Q9SZ54), GPX7_BOVIN  (A6QLY2), 
GPX7_HUMAN  (Q96SL4), GPX7_MOUSE  (Q99LJ6), GPX8A_XENLA (Q6IRC8), 
GPX8B_XENLA (Q5U583), GPX8_ARATH  (Q8LBU2), GPX8_BOVIN  (Q2NL01), 
GPX8_HUMAN  (Q8TED1), GPX8_MOUSE  (Q9D7B7), GPXA_NEIMA  (P0A0T4), 
GPXA_NEIMB  (P0A0T5), GPXA_NEIMC  (P0C2T0), GPXA_NEIMF  (A1KV41), 
GPXC_BRUMA  (P67877), GPXC_BRUPA  (P67878), GPXC_DIRIM  (P52033), 
GPXC_WUCBA  (P35666), GPX_MCV1(Q98234), GPX_PROCL   (G9JJU2)
» more

UniProtKB/Swiss-Prot
False negative sequences
7 sequences

BSAA_STAEQ  (Q5HKZ3), GPWA_PSEWI  (O08368), GPX1_CALJA  (Q0EF99), 
GPX1_SAPAP  (Q4AEI1), GPX2_CALJA  (Q0EF98), GPX8_DANRE  (Q7ZV14), 
GPX8_TETNG  (Q4RSM6)
» more

PDB
[Detailed view]
34 PDB

pdb_00001gp1; pdb_00002f8a; pdb_00002gs3; pdb_00002he3; pdb_00002i3y; pdb_00002obi; pdb_00002p31; pdb_00002r37; pdb_00002v1m; pdb_00002wgr; pdb_00003cmi; pdb_00003cyn; pdb_00003kij; pdb_00005h5q; pdb_00005h5r; pdb_00005h5s; pdb_00005l71; pdb_00006elw; pdb_00006hkq; pdb_00006hn3; pdb_00007fc2; pdb_00007l8k; pdb_00007l8l; pdb_00007l8m; pdb_00007l8q; pdb_00007l8r; pdb_00007u4i; pdb_00007u4j; pdb_00007u4k; pdb_00007u4l; pdb_00007u4m; pdb_00007u4n; pdb_00008q8j; pdb_00008q8n
» more