PROSITE entry PS00764

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PURL: https://purl.expasy.org/prosite/signature/PS00764

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General information about the entry

Entry name [info]	ENDONUCLEASE_III_1
Accession [info]	PS00764
Entry type [info]	PATTERN
Date [info]	01-DEC-1992 CREATED; 01-DEC-2001 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00615

Name and characterization of the entry

Description [info]	Endonuclease III iron-sulfur binding region signature.
Pattern [info]	C-x(3)-[KRSN]-P-[KRAGL]-C-x(2)-C-x(5)-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.

Total number of hits	30 in 30 different sequences
Number of true positive hits	30 in 30 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	24
Number of 'partial' sequences	1

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	55.56 %

Comments [info]

Taxonomic range [info]	Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Site [info]	iron_sulfur at position 1
Site [info]	iron_sulfur at position 6
Site [info]	iron_sulfur at position 8
Site [info]	iron_sulfur at position 10
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	30 sequences END3_BACSU (P39788), END3_ECOL6 (P0AB84), END3_ECOLI (P0AB83), END3_HAEIN (P44319), END3_MYCBO (P63541), END3_MYCLE (Q9CB92), END3_MYCTO (P9WQ10), END3_MYCTU (P9WQ11), END3_RICPR (O05956), END3_SYNY3 (P73715), END3_THEMA (Q9WYK0), END3_TREPA (O83754), MIG_AERPE (Q9YDP0), MIG_METTF (P29588), MUTYH_HUMAN (Q9UIF7), MUTYH_MOUSE (Q99P21), MUTYH_RAT (Q8R5G2), MUTY_BUCAI (P57617), MUTY_BUCAP (Q8K926), MUTY_BUCBP (Q89A45), MUTY_ECOLI (P17802), MUTY_HAEIN (P44320), MUTY_SALTY (Q05869), MYH1_SCHPO (Q10159), NTH1_ARATH (Q9SIC4), NTH_BOVIN (Q2KID2), NTH_CAEEL (P54137), NTH_CHICK (A7M7B9), NTH_ENCCU (Q8SRB8), UVEN_MICLC (P46303) » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	24 sequences DG783_ARATH (F4JCQ3), DME_ARATH (Q8LK56), DML2_ARATH (Q9SR66), DML3_ARATH (O49498), END3_BUCAI (P57219), END3_BUCAP (Q8KA16), END3_BUCBP (Q89AW4), END3_METJA (Q58030), END3_RICCN (Q92GH4), END3_RICFE (Q4UK93), END3_RICTY (Q68W04), MIG_PYRAE (Q7LX22), MUTYH_ARATH (F4JRF4), MUTY_BACSU (O31584), MUTY_GEOSE (P83847), NTH1_YEAST (P31378), NTH2_ARATH (B9DFZ0), NTH2_YEAST (Q08214), NTH_EMENI (C8VC05), NTH_HUMAN (P78549), NTH_MOUSE (O35980), NTH_SCHPO (Q09907), ROS1_ARATH (Q9SJQ6), Y1434_METJA (Q58829) » more
UniProtKB/Swiss-Prot 'Partial' sequences	1 sequence MUTY_AERHY (P46230)
PDB [Detailed view]	18 PDB 1KEA; 1KG2; 1KG3; 1KG4; 1KG5; 1KG6; 1KG7; 1MUD; 1MUN; 1MUY; 1WEF; 1WEG; 1WEI; 2ABK; 3N5N; 7EF8; 7EF9; 8FAY » more