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PROSITE entry PS00782


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00782
Entry name [info] TFIIB
Accession [info] PS00782
Entry type [info] PATTERN
Date [info] 01-DEC-1992 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00624

Name and characterization of the entry

Description [info] Transcription factor TFIIB repeat signature.
Pattern [info] 
G-[KR]-x(3)-[STAGN]-{S}-[LIVMYA]-[GSTA](2)-[CSAV]-[LIVM]-[LIVMFY]-
[LIVMA]-[GSA]-[STAC].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 128 in 73 different sequences
Number of true positive hits 125 in 70 different sequences
Number of 'unknown' hits 0
Number of false positive hits 3 in 3 different sequences
Number of false negative sequences 15
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 97.66 %
Recall (true positives / (true positives + false negatives)) 89.29 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 2
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 70 sequences 

TF2B1_ARATH (P48512), TF2B1_SACS2 (P58111), TF2B1_THEAC (Q9HJM7), 

TF2B1_THEKO (Q5JGN1), TF2B1_THEVO (Q979Q3), TF2B2_ARATH (Q9SS44), 
TF2B2_HALSA (Q9HRE6), TF2B2_HALVD (Q9YGA5), TF2B2_THEAC (Q9HJM2), 
TF2B2_THEKO (P58109), TF2B2_THEVO (Q979P7), TF2B3_HALSA (Q9HHK5), 
TF2B4_HALSA (Q9HR45), TF2B6_HALSA (Q9HSB3), TF2B7_HALSA (Q9HSF7), 
TF2B_AERPE  (Q9Y942), TF2B_ARCFU  (O28970), TF2B_BOVIN  (Q2KIN8), 
TF2B_CAEEL  (O16991), TF2B_CALMQ  (A8MCX6), TF2B_DICDI  (Q54FD6), 
TF2B_DROME  (P29052), TF2B_DROVI  (Q9NHP7), TF2B_ENCCU  (Q8SRP3), 
TF2B_HALVA  (P42198), TF2B_HUMAN  (Q00403), TF2B_IGNH4  (A8AC96), 
TF2B_KLULA  (Q05959), TF2B_MACFA  (Q4R3J5), TF2B_META3  (A6UW60), 
TF2B_METAC  (Q8TT29), TF2B_METB6  (A7IAR4), TF2B_METJA  (Q58192), 
TF2B_METKA  (Q8TX21), TF2B_METM5  (A4G0F2), TF2B_METM6  (A9A8Q0), 
TF2B_METM7  (A6VI28), TF2B_METMA  (P0CW15), TF2B_METMJ  (A3CSQ6), 
TF2B_METMP  (Q6M176), TF2B_METMZ  (P0CW14), TF2B_METPE  (B8GJQ9), 
TF2B_METS3  (A5UKA1), TF2B_METST  (Q2NEL6), TF2B_METTH  (O26971), 
TF2B_METTL  (Q9P9I7), TF2B_METTP  (A0B5T8), TF2B_MOUSE  (P62915), 
TF2B_ORYSJ  (Q8W0W3), TF2B_PONAB  (Q5R886), TF2B_PYRAB  (Q9V0V5), 
TF2B_PYRAE  (Q8ZWS3), TF2B_PYRAR  (A4WMA6), TF2B_PYRFU  (P61998), 
TF2B_PYRHO  (O59151), TF2B_PYRIL  (A1RV37), TF2B_PYRNV  (B1YCX0), 
TF2B_PYROC  (Q977X4), TF2B_PYRWO  (P61999), TF2B_RAT(P62916), 
TF2B_SACSH  (P50387), TF2B_SCHPO  (O13749), TF2B_SOYBN  (P48513), 
TF2B_SULAC  (Q9UWN6), TF2B_SULTO  (Q975S1), TF2B_XENLA  (P29054), 
TF2B_YEAST  (P29055), TF3B_CANAL  (P43072), TF3B_KLULA  (P46070), 
TF3B_YEAST  (P29056)
» more

UniProtKB/Swiss-Prot
False negative sequences		 15 sequences 

BRF2_BOVIN  (Q29S07), BRF2_DANRE  (A8KBY2), BRF2_HUMAN  (Q9HAW0), 

BRF2_MACFA  (Q4R318), BRF2_MOUSE  (Q3UAW9), BRF2_RAT(Q4V8D6), 
BRF2_XENLA  (Q66IW8), BRF2_XENTR  (A4QNR3), TF2B1_HALSA (Q9HNA2), 
TF2B2_SACS2 (P58110), TF2B5_HALSA (Q9HHH8), TF2B_MIMIV  (Q5UPT1), 
TF3B_HUMAN  (Q92994), TF3B_MOUSE  (Q8CFK2), TF3B_SCHPO  (Q9P6R0)
» more

UniProtKB/Swiss-Prot
False positive sequences		 3 sequences 

GPI11_YARLI (Q6C741), HXK6_ORYSJ  (Q8LQ68), KCRS_CHICK  (P11009)


				
	

	

		PDB
[Detailed view]		
		
			100 PDB
			


			1AIS; 1C9B; 1D3U; 1TFB; 1VOL; 2PHG; 3K7A; 4BBR; 4BBS; 4V1N; 4V1O; 5FMF; 
			
				5FYW; 5FZ5; 5IY6; 5IY7; 5IY8; 5IY9; 5IYA; 5IYB; 5IYC; 5IYD; 5OQJ; 5OQM; 
				5SVA; 5WH1; 6CNB; 6CNC; 6CND; 6CNF; 6EU0; 6F40; 6F41; 6F42; 6F44; 6GYK; 
				6GYL; 6GYM; 6O9L; 7EDX; 7EG7; 7EG8; 7EG9; 7EGA; 7EGB; 7EGC; 7ENA; 7ENC; 
				7LBM; 7ML0; 7ML1; 7ML2; 7ML4; 7NVR; 7NVS; 7NVT; 7NVU; 7NVY; 7NVZ; 7NW0; 
				7O4I; 7O4J; 7O72; 7O73; 7O75; 7Q5B; 7UI9; 7UIF; 7UIO; 7ZS9; 7ZSA; 7ZSB; 
				7ZWC; 7ZWD; 7ZX7; 7ZX8; 7ZXE; 8BVW; 8BYQ; 8BZ1; 8CEN; 8CEO; 8FFZ; 8GXQ; 
				8GXS; 8S51; 8S52; 8S5N; 8UMH; 8UMI; 8UOQ; 8UOT; 8WAK; 8WAL; 8WAN; 8WAO; 
				8WAP; 8WAQ; 8WAR; 8WAS
			
			

			» more