PROSITE entry PS00794

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PURL: https://purl.expasy.org/prosite/signature/PS00794

Direct ScanProsite submission

General information about the entry

Entry name [info]	HPPK
Accession [info]	PS00794
Entry type [info]	PATTERN
Date [info]	01-DEC-1992 CREATED; 01-JUL-1999 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00631

Name and characterization of the entry

Description [info]	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature.
Pattern [info]	[KRHD]-x-[GA]-[PSAE]-R-x(2)-D-[LIV]-D-[LIVM](2).

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.

Total number of hits	33 in 33 different sequences
Number of true positive hits	33 in 33 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	5
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	86.84 %

Comments [info]

Taxonomic range [info]	Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

33 sequences

FOL1_DICDI  (Q54YD9), FOL1_PNECA  (P29251), FOL1_YEAST  (P53848),

FOLC_ARATH  (Q1ENB6), FOLKE_LACLA (Q9CGE3), FOLKE_LACLM (Q8GJP4), 
FOLKP_CHLMU (P82602), FOLKP_CHLTR (O84619), FOLM_ARATH  (Q9SZV3), 
FOLM_PEA(O04862), HPPK_AQUAE  (O66550), HPPK_BACSU  (P29252), 
HPPK_CAMJE  (Q9PJ54), HPPK_ECOLI  (P26281), HPPK_HAEIN  (P43777), 
HPPK_HELPJ  (Q9ZM35), HPPK_HELPY  (O25680), HPPK_METEA  (P71512), 
HPPK_MYCBO  (P64144), HPPK_MYCLE  (O69528), HPPK_MYCTO  (P9WNC6), 
HPPK_MYCTU  (P9WNC7), HPPK_PSEAE  (Q9HV71), HPPK_PSEPU  (O87790), 
HPPK_STRP1  (P0C0G3), HPPK_STRP3  (P0DB10), HPPK_STRP6  (Q5XCA6), 
HPPK_STRP8  (Q8P151), HPPK_STRPQ  (P0DB11), HPPK_STRPY  (P0C0G2), 
HPPK_SYNY3  (P72736), SULD_STRPN  (P22291), SULD_STRR6  (P59657)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

5 sequences

FOL1_SCHPO  (Q4LB35), FOLKP_CHLCV (Q821E2), FOLKP_CHLPN (Q9Z7E8),

HPPK_PORG3  (B2RI92), HPPK_PORGI  (P0C936)

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PDB
[Detailed view]

56 PDB

pdb_00001cbk; pdb_00001dy3; pdb_00001eq0; pdb_00001eqm; pdb_00001ex8; pdb_00001hka; pdb_00001hq2; pdb_00001im6; pdb_00001q0n; pdb_00001rao; pdb_00001rb0; pdb_00001rtz; pdb_00001ru1; pdb_00001ru2; pdb_00001tmj; pdb_00001tmm; pdb_00002bmb; pdb_00002cg8; pdb_00002f63; pdb_00002f65; pdb_00003hcx; pdb_00003hd1; pdb_00003hd2; pdb_00003hsd; pdb_00003hsg; pdb_00003hsj; pdb_00003hsz; pdb_00003ht0; pdb_00003ip0; pdb_00003kue; pdb_00003kug; pdb_00003kuh; pdb_00003ud5; pdb_00003ude; pdb_00003udv; pdb_00004f7v; pdb_00004m5g; pdb_00004m5h; pdb_00004m5i; pdb_00004m5j; pdb_00004m5k; pdb_00004m5l; pdb_00004m5m; pdb_00004m5n; pdb_00005etk; pdb_00005etl; pdb_00005etm; pdb_00005etn; pdb_00005eto; pdb_00005etp; pdb_00006an4; pdb_00006an6; pdb_00007kdo; pdb_00007kdr; pdb_00007mpy; pdb_00008sif
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