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PROSITE entry PS00832


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00832
Entry name [info] 25A_SYNTH_1
Accession [info] PS00832
Entry type [info] PATTERN
Date [info] 01-OCT-1993 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00653

Name and characterization of the entry

Description [info] 2'-5'-oligoadenylate synthases signature 1.
Pattern [info] 
G-S-x-[AG]-[KRN]-x-T-x-L-[KRN]-x(3)-[DE]-x-[DET]-[LM]-[VI]-x-F.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 16 in 13 different sequences
Number of true positive hits 16 in 13 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 4
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 80.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 3
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 13 sequences 

OAS1A_MOUSE (P11928), OAS1A_RAT   (Q05961), OAS1_HUMAN  (P00973), 

OAS1_PIG(Q29599), OAS2_HUMAN  (P29728), OAS2_MOUSE  (E9Q9A9), 
OAS2_RAT(Q5MYU0), OAS3_HUMAN  (Q9Y6K5), OAS3_MOUSE  (Q8VI93), 
OAS3_RAT(Q5MYT7), OASL2_MOUSE (Q9Z2F2), OASL2_RAT   (Q5MYT9), 
OASL_HUMAN  (Q15646)
» more

UniProtKB/Swiss-Prot
False negative sequences		 4 sequences 

OAS1B_MOUSE (Q60856), OAS2_BOVIN  (F1N3B8), OASL1_MOUSE (Q8VI94), 

OASL1_RAT   (G3V645)
» more

PDB
[Detailed view]		 8 PDB

1PX5; 4IG8; 4RWN; 4RWO; 4RWP; 4RWQ; 4S3N; 4XQ7