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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS00833


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PURL: https://purl.expasy.org/prosite/signature/PS00833

Direct ScanProsite submission
General information about the entry

Entry name [info] 25A_SYNTH_2
Accession [info] PS00833
Entry type [info] PATTERN
Date [info] 01-OCT-1993 CREATED;
01-JUL-1999 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00653

Name and characterization of the entry

Description [info] 2'-5'-oligoadenylate synthases signature 2.
Pattern [info] 
R-P-[VI]-I-L-D-P-x-[DE]-P-T.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 24 in 17 different sequences
Number of true positive hits 24 in 17 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 2
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 17 sequences 

OAS1A_MOUSE (P11928), OAS1A_RAT   (Q05961), OAS1B_MOUSE (Q60856), 

OAS1_HUMAN  (P00973), OAS1_PIG(Q29599), OAS2_BOVIN  (F1N3B8), 
OAS2_HUMAN  (P29728), OAS2_MOUSE  (E9Q9A9), OAS2_RAT(Q5MYU0), 
OAS3_HUMAN  (Q9Y6K5), OAS3_MOUSE  (Q8VI93), OAS3_RAT(Q5MYT7), 
OASL1_MOUSE (Q8VI94), OASL1_RAT   (G3V645), OASL2_MOUSE (Q9Z2F2), 
OASL2_RAT   (Q5MYT9), OASL_HUMAN  (Q15646)
» more

PDB
[Detailed view]		 8 PDB

pdb_00001px5; pdb_00004ig8; pdb_00004rwn; pdb_00004rwo; pdb_00004rwp; pdb_00004rwq; pdb_00004s3n; pdb_00004xq7