PROSITE entry PS00836

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS00836
Entry name [info]	ALADH_PNT_1
Accession [info]	PS00836
Entry type [info]	PATTERN
Date [info]	01-OCT-1993 CREATED; 01-APR-2006 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00654

Name and characterization of the entry

Description [info]	Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1.
Pattern [info]	[GA]-[LIVM]-[PKV]-x(0,1)-E-x(3)-[NG]-E-x(1,3)-R-[VT]-[AG]-x-[ST]-P-x- [GSTVN]-[VA]-x(2)-[LI]-x-[KRHNGSED]-x-G.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	36 in 36 different sequences
Number of true positive hits	36 in 36 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	10
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	78.26 %

Comments [info]

Taxonomic range [info]	Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Version [info]	2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

36 sequences

DHA1_STAA3  (Q2FH00), DHA1_STAA8  (Q2FYJ2), DHA1_STAAC  (Q5HFY4),

DHA1_STAAM  (P63478), DHA1_STAAN  (P99151), DHA1_STAAR  (Q6GGW9), 
DHA1_STAAS  (Q6G9C3), DHA1_STAAW  (Q8NWQ3), DHA2_STAA3  (Q2FG29), 
DHA2_STAA8  (Q2FXL7), DHA2_STAAB  (Q2YTD1), DHA2_STAAC  (Q5HF65), 
DHA2_STAAM  (Q931P7), DHA2_STAAN  (Q99TF4), DHA2_STAAR  (Q6GFZ8), 
DHA2_STAAS  (Q6G8L8), DHA2_STAAW  (Q8NW54), DHA_BACSU   (Q08352), 
DHA_GEOSE   (P17557), DHA_LYSSH   (P17556), DHA_MYCS2   (A0QVQ8), 
DHA_MYCTO   (P9WQB0), DHA_MYCTU   (P9WQB1), DHA_OCEIH   (Q8CX61), 
DHA_STAEQ   (Q5HNJ6), DHA_STAES   (Q8CNW8), DHA_STAHJ   (Q4L750), 
NNTM_BOVIN  (P11024), NNTM_HUMAN  (Q13423), NNTM_MOUSE  (Q61941), 
NNTM_SHEEP  (W5PFI3), PNTAA_RHORT (Q2RSB2), PNTAA_RHORU (P0C186), 
PNTAA_RICPR (P41077), PNTA_ECOLI  (P07001), PNTA_HAEIN  (P43842)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

10 sequences

AASS_ARATH  (Q9SMZ4), AASS_BOVIN  (A8E657), AASS_HUMAN  (Q9UDR5),

AASS_MOUSE  (Q99K67), AASS_RAT(A2VCW9), DHA1_STAAB  (Q2YY66), 
DHA_HALED   (E1V931), DHA_METMP   (Q6LX40), DHA_STAS1   (Q49YD9), 
PNTA_CERSP  (Q9ALA2)

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PDB
[Detailed view]

30 PDB

1F8G; 1HZZ; 1L7D; 1L7E; 1NM5; 1PTJ; 1U28; 1U2D; 1U2G; 1X13; 1X14; 1X15; 1XLT; 2BRU; 2FR8; 2FRD; 2FSV; 2OO5; 2OOR; 2VHV; 2VHW; 2VHX; 2VHY; 2VHZ; 2VOE; 2VOJ; 6O7F; 6QTI; 6QUE; 6S59
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