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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
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Amos Bairoch

PROSITE entry PS00839


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PURL: https://purl.expasy.org/prosite/signature/PS00839

Direct ScanProsite submission
General information about the entry

Entry name [info] SUMT_1
Accession [info] PS00839
Entry type [info] PATTERN
Date [info] 01-OCT-1993 CREATED;
01-JUL-1998 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00656

Name and characterization of the entry

Description [info] Uroporphyrin-III C-methyltransferase signature 1.
Pattern [info]
[LIVM]-[GS]-[STAL]-G-P-G-x(3)-[LIVMFY]-[LIVM]-T-[LIVM]-[KRHQG]-[AG].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 130 in 130 different sequences
Number of true positive hits 130 in 130 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 43
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 75.14 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
130 sequences

CBIF_METJA  (Q58973), CBIF_PRIMG  (O87696), CBIF_SALTI  (P0A2H0), 
CBIF_SALTY  (P0A2G9), CBIL_SALTY  (Q05593), COBIJ_MYCBO (P66878), 
COBIJ_MYCTO (P9WGB2), COBIJ_MYCTU (P9WGB3), COBI_SINSX  (P21639), 
COBM_MYCTO  (P9WGB0), COBM_MYCTU  (P9WGB1), COBM_PSEAE  (Q9HZP9), 
COBM_RHOCB  (O68100), COBM_RHOER  (Q53138), COBM_SINSX  (P21922), 
CYSG1_AERS4 (A4SHL4), CYSG1_CROS8 (A7MJ67), CYSG1_KLEP7 (A6TD45), 
CYSG1_PECAS (Q6D1A4), CYSG1_SERP5 (A8G9Y3), CYSG1_YERE8 (A1JJS8), 
CYSG1_YERP3 (A7FLY4), CYSG1_YERPN (Q1CLS2), CYSG1_YERPP (A4TGU8), 
CYSG1_YERPS (Q66EC9), CYSG2_AERHH (A0KP37), CYSG2_AERS4 (A4SRH0), 
CYSG2_CROS8 (A7MKK9), CYSG2_KLEP7 (A6TF07), CYSG2_PECAS (Q6CZS0), 
CYSG2_SERP5 (A8GKQ1), CYSG2_YERE8 (A1JSB7), CYSG2_YERP3 (A7FNS9), 
CYSG2_YERPN (Q1CCP6), CYSG2_YERPP (A4TPZ1), CYSG2_YERPS (Q664M6), 
CYSG3_AERHH (A0KQJ4), CYSG_ACIAD  (Q6F8G6), CYSG_ACTP7  (B3GZA0), 
CYSG_ACTPJ  (B0BTC2), CYSG_ACTSZ  (A6VPZ6), CYSG_ALKEH  (Q0A812), 
CYSG_BAUCH  (Q1LTP4), CYSG_BLOFL  (Q7VQG9), CYSG_BLOPB  (Q493N1), 
CYSG_BORA1  (Q2KWB0), CYSG_BORBR  (Q7WMM4), CYSG_BORPA  (Q7WB57), 
CYSG_BORPD  (A9HZV6), CYSG_BORPE  (Q7VZ77), CYSG_BUCAI  (P57500), 
CYSG_CITK8  (A8AQS4), CYSG_ECO24  (A7ZSP4), CYSG_ECO27  (B7UK79), 
CYSG_ECO45  (B7MCY5), CYSG_ECO55  (B7L4P2), CYSG_ECO57  (P0AEA9), 
CYSG_ECO5E  (B5YTS6), CYSG_ECO7I  (B7NMD7), CYSG_ECO81  (B7N1F1), 
CYSG_ECO8A  (B7M1S1), CYSG_ECOBW  (C4ZUM4), CYSG_ECODH  (B1X716), 
CYSG_ECOHS  (A8A5H5), CYSG_ECOK1  (A1AGQ2), CYSG_ECOL5  (Q0TC92), 
CYSG_ECOL6  (Q8FCW8), CYSG_ECOLC  (B1IP96), CYSG_ECOLI  (P0AEA8), 
CYSG_ECOLU  (B7NDX8), CYSG_ECOSE  (B6I2S7), CYSG_ECOSM  (B1LHG9), 
CYSG_ECOUT  (Q1R5R3), CYSG_EDWI9  (C5BGP8), CYSG_ENT38  (A4WFH1), 
CYSG_ESCF3  (B7LS75), CYSG_GLUDA  (A9H259), CYSG_GLUOX  (Q5FP95), 
CYSG_MANSM  (Q65T49), CYSG_METCA  (Q606C9), CYSG_NEIM0  (A9LZ77), 
CYSG_NEIMA  (P57001), CYSG_NEIMB  (P95370), CYSG_NEIMF  (A1KU10), 
CYSG_PHOLL  (Q7N8L2), CYSG_PHOPR  (Q6LM67), CYSG_PSET1  (Q3ILQ9), 
CYSG_PSYIN  (A1SRP9), CYSG_SALA4  (B5F8J0), CYSG_SALAR  (A9MME5), 
CYSG_SALCH  (Q57IZ5), CYSG_SALDC  (B5FJQ1), CYSG_SALEP  (B5R2C7), 
CYSG_SALG2  (B5R7N6), CYSG_SALHS  (B4TKQ4), CYSG_SALNS  (B4SVI1), 
CYSG_SALPA  (Q5PLV8), CYSG_SALPB  (A9MT45), CYSG_SALPC  (C0Q0F3), 
CYSG_SALPK  (B5BH22), CYSG_SALSV  (B4TY38), CYSG_SALTI  (Q8Z201), 
CYSG_SALTY  (P25924), CYSG_SHIB3  (B2U3H4), CYSG_SHIBS  (Q31VS0), 
CYSG_SHIDS  (Q32AZ8), CYSG_SHIF8  (Q0SZU8), CYSG_SHIFL  (Q83JB3), 
CYSG_SHISS  (Q3YWQ3), CYSG_SODGM  (Q2NVN0), CYSG_TOLAT  (C4LAG5), 
CYSG_YERPA  (Q1C2P9), CYSG_YERPE  (Q74Y23), CYSG_ZYMMO  (Q5NRM4), 
HEM4_RUMJO  (Q59294), NASF_BACSU  (P42437), NIRE_PARDP  (Q51701), 
SUMT_BACSU  (O34744), SUMT_CYACA  (O19889), SUMT_METBF  (Q46BL0), 
SUMT_METIV  (P29564), SUMT_METJA  (Q58375), SUMT_PRIMG  (P29928), 
SUMT_PSEAE  (Q9I2W4), SUMT_PSEFL  (P37725), SUMT_SINSX  (P21631), 
SUMT_SYNE7  (P42451), SUMT_SYNY3  (Q55749), SUMT_YEAST  (P36150), 
UPM1_ARATH  (Q42606)
» more

UniProtKB/Swiss-Prot
False negative sequences
43 sequences

COBI_PSEAE  (Q9HZU3), CYSG1_AERHH (A0KLD7), CYSG1_HALHL (A1WWP8), 
CYSG2_HALHL (A1WYD5), CYSG_ALCBS  (Q0VQ05), CYSG_AZOVD  (C1DKY7), 
CYSG_CHRVO  (Q7NZV7), CYSG_ECTM1  (A4XUX3), CYSG_HAHCH  (Q2SJB7), 
CYSG_HYDCU  (Q31GG8), CYSG_METFK  (Q1H3L5), CYSG_NITEC  (Q0AHC1), 
CYSG_NITEU  (Q820Q4), CYSG_NITMU  (Q2Y6L7), CYSG_NITOC  (Q3JCS0), 
CYSG_PSE14  (Q48H75), CYSG_PSEA6  (Q15YU1), CYSG_PSEA8  (B7UW11), 
CYSG_PSEAB  (Q02NA3), CYSG_PSEAE  (Q9I0M7), CYSG_PSEE4  (Q1IBC9), 
CYSG_PSEF5  (Q4K9V8), CYSG_PSEFS  (C3JY53), CYSG_PSEP1  (A5W1H7), 
CYSG_PSEP7  (A6V4H6), CYSG_PSEPF  (Q3KA85), CYSG_PSEPK  (Q88FT3), 
CYSG_PSEPW  (B1JBD9), CYSG_PSESM  (Q87ZT0), CYSG_PSEU2  (Q4ZRL6), 
CYSG_PSYA2  (Q4FSU1), CYSG_PSYCK  (Q1QAX7), CYSG_PSYWF  (A5WEG6), 
CYSG_RUTMC  (A1AVU5), CYSG_SACD2  (Q21K21), CYSG_STUS1  (A4VLU6), 
CYSG_THIDA  (Q3SG32), CYSG_THISH  (B8GUD3), CYSG_VESOH  (A5CXE4), 
CYSG_XYLF2  (B2I985), CYSG_XYLFA  (Q9PF46), CYSG_XYLFM  (B0U4X0), 
CYSG_XYLFT  (Q87AI5)
» more

PDB
[Detailed view]
20 PDB

pdb_00001cbf; pdb_00001pjq; pdb_00001pjs; pdb_00001pjt; pdb_00001s4d; pdb_00002cbf; pdb_00003ndc; pdb_00003nei; pdb_00006p5x; pdb_00006p5z; pdb_00006p7c; pdb_00006p7d; pdb_00006pqz; pdb_00006pr0; pdb_00006pr1; pdb_00006pr2; pdb_00006pr3; pdb_00006pr4; pdb_00006ulu; pdb_00006veb
» more