PROSITE entry PS00839

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS00839
Entry name [info]	SUMT_1
Accession [info]	PS00839
Entry type [info]	PATTERN
Date [info]	01-OCT-1993 CREATED; 01-JUL-1998 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00656

Name and characterization of the entry

Description [info]	Uroporphyrin-III C-methyltransferase signature 1.
Pattern [info]	[LIVM]-[GS]-[STAL]-G-P-G-x(3)-[LIVMFY]-[LIVM]-T-[LIVM]-[KRHQG]-[AG].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	130 in 130 different sequences
Number of true positive hits	130 in 130 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	43
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	75.14 %

Comments [info]

Taxonomic range [info]	Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

130 sequences

CBIF_METJA  (Q58973), CBIF_PRIMG  (O87696), CBIF_SALTI  (P0A2H0),

CBIF_SALTY  (P0A2G9), CBIL_SALTY  (Q05593), COBIJ_MYCBO (P66878), 
COBIJ_MYCTO (P9WGB2), COBIJ_MYCTU (P9WGB3), COBI_SINSX  (P21639), 
COBM_MYCTO  (P9WGB0), COBM_MYCTU  (P9WGB1), COBM_PSEAE  (Q9HZP9), 
COBM_RHOCB  (O68100), COBM_RHOER  (Q53138), COBM_SINSX  (P21922), 
CYSG1_AERS4 (A4SHL4), CYSG1_CROS8 (A7MJ67), CYSG1_KLEP7 (A6TD45), 
CYSG1_PECAS (Q6D1A4), CYSG1_SERP5 (A8G9Y3), CYSG1_YERE8 (A1JJS8), 
CYSG1_YERP3 (A7FLY4), CYSG1_YERPN (Q1CLS2), CYSG1_YERPP (A4TGU8), 
CYSG1_YERPS (Q66EC9), CYSG2_AERHH (A0KP37), CYSG2_AERS4 (A4SRH0), 
CYSG2_CROS8 (A7MKK9), CYSG2_KLEP7 (A6TF07), CYSG2_PECAS (Q6CZS0), 
CYSG2_SERP5 (A8GKQ1), CYSG2_YERE8 (A1JSB7), CYSG2_YERP3 (A7FNS9), 
CYSG2_YERPN (Q1CCP6), CYSG2_YERPP (A4TPZ1), CYSG2_YERPS (Q664M6), 
CYSG3_AERHH (A0KQJ4), CYSG_ACIAD  (Q6F8G6), CYSG_ACTP7  (B3GZA0), 
CYSG_ACTPJ  (B0BTC2), CYSG_ACTSZ  (A6VPZ6), CYSG_ALKEH  (Q0A812), 
CYSG_BAUCH  (Q1LTP4), CYSG_BLOFL  (Q7VQG9), CYSG_BLOPB  (Q493N1), 
CYSG_BORA1  (Q2KWB0), CYSG_BORBR  (Q7WMM4), CYSG_BORPA  (Q7WB57), 
CYSG_BORPD  (A9HZV6), CYSG_BORPE  (Q7VZ77), CYSG_BUCAI  (P57500), 
CYSG_CITK8  (A8AQS4), CYSG_ECO24  (A7ZSP4), CYSG_ECO27  (B7UK79), 
CYSG_ECO45  (B7MCY5), CYSG_ECO55  (B7L4P2), CYSG_ECO57  (P0AEA9), 
CYSG_ECO5E  (B5YTS6), CYSG_ECO7I  (B7NMD7), CYSG_ECO81  (B7N1F1), 
CYSG_ECO8A  (B7M1S1), CYSG_ECOBW  (C4ZUM4), CYSG_ECODH  (B1X716), 
CYSG_ECOHS  (A8A5H5), CYSG_ECOK1  (A1AGQ2), CYSG_ECOL5  (Q0TC92), 
CYSG_ECOL6  (Q8FCW8), CYSG_ECOLC  (B1IP96), CYSG_ECOLI  (P0AEA8), 
CYSG_ECOLU  (B7NDX8), CYSG_ECOSE  (B6I2S7), CYSG_ECOSM  (B1LHG9), 
CYSG_ECOUT  (Q1R5R3), CYSG_EDWI9  (C5BGP8), CYSG_ENT38  (A4WFH1), 
CYSG_ESCF3  (B7LS75), CYSG_GLUDA  (A9H259), CYSG_GLUOX  (Q5FP95), 
CYSG_MANSM  (Q65T49), CYSG_METCA  (Q606C9), CYSG_NEIM0  (A9LZ77), 
CYSG_NEIMA  (P57001), CYSG_NEIMB  (P95370), CYSG_NEIMF  (A1KU10), 
CYSG_PHOLL  (Q7N8L2), CYSG_PHOPR  (Q6LM67), CYSG_PSET1  (Q3ILQ9), 
CYSG_PSYIN  (A1SRP9), CYSG_SALA4  (B5F8J0), CYSG_SALAR  (A9MME5), 
CYSG_SALCH  (Q57IZ5), CYSG_SALDC  (B5FJQ1), CYSG_SALEP  (B5R2C7), 
CYSG_SALG2  (B5R7N6), CYSG_SALHS  (B4TKQ4), CYSG_SALNS  (B4SVI1), 
CYSG_SALPA  (Q5PLV8), CYSG_SALPB  (A9MT45), CYSG_SALPC  (C0Q0F3), 
CYSG_SALPK  (B5BH22), CYSG_SALSV  (B4TY38), CYSG_SALTI  (Q8Z201), 
CYSG_SALTY  (P25924), CYSG_SHIB3  (B2U3H4), CYSG_SHIBS  (Q31VS0), 
CYSG_SHIDS  (Q32AZ8), CYSG_SHIF8  (Q0SZU8), CYSG_SHIFL  (Q83JB3), 
CYSG_SHISS  (Q3YWQ3), CYSG_SODGM  (Q2NVN0), CYSG_TOLAT  (C4LAG5), 
CYSG_YERPA  (Q1C2P9), CYSG_YERPE  (Q74Y23), CYSG_ZYMMO  (Q5NRM4), 
HEM4_RUMJO  (Q59294), NASF_BACSU  (P42437), NIRE_PARDP  (Q51701), 
SUMT_BACSU  (O34744), SUMT_CYACA  (O19889), SUMT_METBF  (Q46BL0), 
SUMT_METIV  (P29564), SUMT_METJA  (Q58375), SUMT_PRIMG  (P29928), 
SUMT_PSEAE  (Q9I2W4), SUMT_PSEFL  (P37725), SUMT_SINSX  (P21631), 
SUMT_SYNE7  (P42451), SUMT_SYNY3  (Q55749), SUMT_YEAST  (P36150), 
UPM1_ARATH  (Q42606)

» more

Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

43 sequences

COBI_PSEAE  (Q9HZU3), CYSG1_AERHH (A0KLD7), CYSG1_HALHL (A1WWP8),

CYSG2_HALHL (A1WYD5), CYSG_ALCBS  (Q0VQ05), CYSG_AZOVD  (C1DKY7), 
CYSG_CHRVO  (Q7NZV7), CYSG_ECTM1  (A4XUX3), CYSG_HAHCH  (Q2SJB7), 
CYSG_HYDCU  (Q31GG8), CYSG_METFK  (Q1H3L5), CYSG_NITEC  (Q0AHC1), 
CYSG_NITEU  (Q820Q4), CYSG_NITMU  (Q2Y6L7), CYSG_NITOC  (Q3JCS0), 
CYSG_PSE14  (Q48H75), CYSG_PSEA6  (Q15YU1), CYSG_PSEA7  (A6V4H6), 
CYSG_PSEA8  (B7UW11), CYSG_PSEAB  (Q02NA3), CYSG_PSEAE  (Q9I0M7), 
CYSG_PSEE4  (Q1IBC9), CYSG_PSEF5  (Q4K9V8), CYSG_PSEFS  (C3JY53), 
CYSG_PSEP1  (A5W1H7), CYSG_PSEPF  (Q3KA85), CYSG_PSEPK  (Q88FT3), 
CYSG_PSEPW  (B1JBD9), CYSG_PSESM  (Q87ZT0), CYSG_PSEU2  (Q4ZRL6), 
CYSG_PSYA2  (Q4FSU1), CYSG_PSYCK  (Q1QAX7), CYSG_PSYWF  (A5WEG6), 
CYSG_RUTMC  (A1AVU5), CYSG_SACD2  (Q21K21), CYSG_STUS1  (A4VLU6), 
CYSG_THIDA  (Q3SG32), CYSG_THISH  (B8GUD3), CYSG_VESOH  (A5CXE4), 
CYSG_XYLF2  (B2I985), CYSG_XYLFA  (Q9PF46), CYSG_XYLFM  (B0U4X0), 
CYSG_XYLFT  (Q87AI5)

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PDB
[Detailed view]

20 PDB

1CBF; 1PJQ; 1PJS; 1PJT; 1S4D; 2CBF; 3NDC; 3NEI; 6P5X; 6P5Z; 6P7C; 6P7D; 6PQZ; 6PR0; 6PR1; 6PR2; 6PR3; 6PR4; 6ULU; 6VEB
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