We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
PROSITE entry PS00841
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PURL: https://purl.expasy.org/prosite/signature/PS00841
Direct ScanProsite submission
General information about the entry
| Entry name [info] | XPG_1 |
| Accession [info] | PS00841 |
| Entry type [info] | PATTERN |
| Date [info] |
01-OCT-1993 CREATED;
01-APR-2006 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00658 |
Name and characterization of the entry
| Description [info] | XPG protein signature 1. |
| Pattern [info] |
[VILT]-[KREIT]-[PV]-x-[FYIL]-[VI]-[FW]-D-G-x(2)-[PILHSTF]-x-[LVCQMFAKS]- K. |
Numerical results [info]
| Total number of hits | 189 in 189 different sequences |
| Number of true positive hits | 189 in 189 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 26 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 87.91 % |
Comments [info]
| Taxonomic range [info] | Archaea, Eukaryotes, Eukaryotic viruses |
| Maximum number of repetitions [info] | 1 |
| Version [info] | 2 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
189 sequences
DIN7_YEAST (Q12086), ERCC5_HUMAN (P28715), ERCC5_MOUSE (P35689), ERCC5_XENLA (P14629), EXO1_DANRE (Q803U7), EXO1_DROME (Q24558), EXO1_HUMAN (Q9UQ84), EXO1_MOUSE (Q9QZ11), EXO1_ORYSJ (Q60GC1), EXO1_SCHPO (P53695), EXO1_XENLA (Q9W6K2), EXO1_YEAST (P39875), FEN11_LACBS (B0DSN9), FEN11_ORYSI (B8AW67), FEN11_ORYSJ (Q9SXQ6), FEN11_PHYPA (A9S0B8), FEN11_SORBI (C5YUK3), FEN12_LACBS (B0E412), FEN12_ORYSI (B8AMS4), FEN12_ORYSJ (Q75LI2), FEN12_PHYPA (A9U328), FEN12_SORBI (C5WU23), FEN1A_DANRE (Q6TNU4), FEN1A_XENLA (P70040), FEN1B_XENLA (P70054), FEN1_AEDAE (Q178M1), FEN1_AJECH (C6HQJ2), FEN1_AJECN (A6QV55), FEN1_AJEDR (C5GPA7), FEN1_ANOFI (C3KJE6), FEN1_ANOGA (Q7Q323), FEN1_ARATH (O65251), FEN1_ARTOC (C5FZT5), FEN1_ASPCL (A1CJ75), FEN1_ASPFC (B0XZ33), FEN1_ASPFN (B8NV37), FEN1_ASPFU (Q4WWJ1), FEN1_ASPNC (A5ABU3), FEN1_ASPTN (Q0CBS0), FEN1_BLAGS (C5JVG7), FEN1_BOVIN (Q58DH8), FEN1_BRAFL (C3ZBT0), FEN1_BRUMA (A8QCH0), FEN1_CAEBR (A8XL25), FEN1_CAEEL (Q9N3T2), FEN1_CANAL (Q5A6K8), FEN1_CANAW (C4YLS2), FEN1_CANDC (B9WLQ5), FEN1_CANGA (Q6FM28), FEN1_CANTT (C5M2X8), FEN1_CHICK (Q5ZLN4), FEN1_CHLRE (A8J2Z9), FEN1_CLAL4 (C4YBJ8), FEN1_COPC7 (A8NQC2), FEN1_COPCI (Q76F73), FEN1_CRYMR (B6AFP1), FEN1_CRYNB (P0CS61), FEN1_CRYNJ (P0CS60), FEN1_CRYPI (A3FPN7), FEN1_DEBHA (Q6BLF4), FEN1_DICDI (Q54NU0), FEN1_DROAN (B3MDA3), FEN1_DROER (B3NP61), FEN1_DROGR (B4J6M4), FEN1_DROME (Q7K7A9), FEN1_DROMO (B4KNM1), FEN1_DROPE (B4GIM3), FEN1_DROPS (B5DUR8), FEN1_DROSE (B4HTA1), FEN1_DROSI (B4QIG6), FEN1_DROVI (B4LM90), FEN1_DROWI (B4MR84), FEN1_DROYA (B4P5U9), FEN1_EMENI (Q5B9L6), FEN1_ENTDS (B0EN90), FEN1_ENTH1 (C4M6G8), FEN1_EREGS (Q75DS8), FEN1_FUSV7 (C7Z125), FEN1_GLOMM (D3TQJ5), FEN1_HETP5 (D3BN56), FEN1_HUMAN (P39748), FEN1_KLULA (Q6CLH4), FEN1_KOMPG (C4QZ20), FEN1_LACTC (C5DGG4), FEN1_LEIBR (A4HFE4), FEN1_LEIIN (A4I2L4), FEN1_LEIMA (Q4FYU7), FEN1_LODEL (A5E121), FEN1_MACFA (Q4R5U5), FEN1_MAIZE (B4FHY0), FEN1_MICCC (C1E3X9), FEN1_MONBE (A9VB27), FEN1_MOUSE (P39749), FEN1_MYCMD (Q4P1V1), FEN1_NAEGR (D2V434), FEN1_NEMVE (A7RRJ0), FEN1_NEOFI (A1D8A4), FEN1_NEUCR (A7UW97), FEN1_OSMMO (C1BM18), FEN1_OSTLU (A4S1G4), FEN1_OSTTA (Q013G9), FEN1_PENRW (B6HEM2), FEN1_PHANO (Q0UZR3), FEN1_PHATC (B7G7Y7), FEN1_PHYIT (D0MY34), FEN1_PICGU (A5DCF5), FEN1_PICST (A3M056), FEN1_PLABA (Q4Z015), FEN1_PLACU (Q4XXP8), FEN1_PLAF7 (Q7K734), FEN1_PLAFA (Q9GZ01), FEN1_PLAKH (B3L014), FEN1_PLAVS (A5KAL1), FEN1_PLAYO (Q7RME3), FEN1_PYRO7 (A4QS18), FEN1_PYRTR (B2VTT3), FEN1_RAT(Q5XIP6), FEN1_SALSA (B9EMY6), FEN1_SCHJY (B6JYI7), FEN1_SCHPO (P39750), FEN1_SHEEP (C8BKD0), FEN1_SORMK (D1ZT73), FEN1_SOYBN (C6TEX6), FEN1_TALMQ (B6QT52), FEN1_TALSN (B8MNF2), FEN1_THAPS (B8C6S5), FEN1_TRIAD (B3RVF0), FEN1_TRYB2 (Q57WW6), FEN1_TRYB9 (C9ZKW4), FEN1_TRYCC (Q4DKQ5), FEN1_UNCRE (C4JDR3), FEN1_VANPO (A7TJ59), FEN1_XENTR (B1H158), FEN1_XIPMA (Q5I4H3), FEN1_YARLI (Q6C116), FEN1_YEAS1 (B3LQY3), FEN1_YEAS2 (C7GVJ8), FEN1_YEAS7 (A6ZZK4), FEN1_YEAS8 (C8ZC62), FEN1_YEAST (P26793), FEN1_ZYGRC (C5DZA9), FEN_AERPE (Q9YFY5), FEN_ARCFU (O29975), FEN_CALMQ (A8M9L3), FEN_CENSY (A0RU95), FEN_HALS3 (B0R5F5), FEN_HALSA (Q9HQ27), FEN_HALWD (Q18HK0), FEN_IGNH4 (A8AAC1), FEN_KORCO (B1L6R9), FEN_METAC (Q8TIY5), FEN_METB6 (A7IA59), FEN_METBF (Q46D63), FEN_METBU (Q12UT1), FEN_METHJ (Q2FNC9), FEN_METKA (Q8TXU4), FEN_METLZ (A2SQC6), FEN_METMA (Q8PYF6), FEN_METMJ (A3CWV2), FEN_METPE (B8GIA0), FEN_METS3 (A5UL52), FEN_METST (Q2NFD4), FEN_METTH (O27670), FEN_METTP (A0B9M7), FEN_NANEQ (P61942), FEN_NATPD (Q3IPG8), FEN_NITMS (A9A4B0), FEN_PICTO (Q6L2I9), FEN_PYRAB (Q9V0P9), FEN_PYRAE (Q8ZYN2), FEN_PYRAR (A4WNC4), FEN_PYRCJ (A3MY15), FEN_PYRFU (O93634), FEN_PYRHO (O50123), FEN_PYRIL (A1RSC7), FEN_PYRNV (B1YC46), FEN_SACS2 (Q980U8), FEN_SULAC (Q4JAN1), FEN_SULTO (Q976H6), FEN_THEAC (Q9HJD4), FEN_THEGJ (C5A639), FEN_THEKO (Q5JGN0), FEN_THEON (B6YWX4), FEN_THEPD (A1RWY2), FEN_THESM (C6A1U9), FEN_THEVO (Q97B98), RAD13_SCHPO (P28706), RAD2_YEAST (P07276), UVH3_ARATH (Q9ATY5)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
26 sequences
EXO1_ARATH (Q8L6Z7), FEN11_PARTE (A0CXT3), FEN12_PARTE (A0CYG2), FEN1B_DANRE (B0UXL7), FEN1_BABBO (A7AX58), FEN1_ENCCU (Q8SS91), FEN1_ENTBH (B7XHS8), FEN1_GIAIC (A8B672), FEN1_TETTS (A4VDN2), FEN1_THEAN (Q4UFP0), FEN1_THEPA (Q4N3S6), FEN_HALMA (Q5V5T7), FEN_HYPBU (A2BMI0), FEN_META3 (A6UX46), FEN_METAR (Q0W6I0), FEN_METJA (Q58839), FEN_STAMF (A3DMG2), GENL1_ARATH (Q9LPD2), GENL1_ORYSJ (Q64MA3), GENL2_ARATH (Q9M2Z3), GENL2_ORYSJ (Q8W5R1), GEN_DROME (Q9VRJ0), GEN_DROPS (Q29FC1), GEN_HUMAN (Q17RS7), GEN_MOUSE (Q8BMI4), VF369_IIV6 (Q91FF5)» more |
| PDB [Detailed view] |
60 PDB
pdb_00001b43; pdb_00001mc8; pdb_00001rxv; pdb_00001rxw; pdb_00001ul1; pdb_00002izo; pdb_00003q8k; pdb_00003q8l; pdb_00003q8m; pdb_00003qe9; pdb_00003qea; pdb_00003qeb; pdb_00004q0r; pdb_00004q0w; pdb_00004q0z; pdb_00004q10; pdb_00004wa8; pdb_00005fv7; pdb_00005k97; pdb_00005kse; pdb_00005uzv; pdb_00005v04; pdb_00005v05; pdb_00005v06; pdb_00005v07; pdb_00005v08; pdb_00005v09; pdb_00005v0a; pdb_00005v0b; pdb_00005v0c; pdb_00005v0d; pdb_00005v0e; pdb_00005zod; pdb_00005zoe; pdb_00005zof; pdb_00005zog; pdb_00006tnz; pdb_00006tur; pdb_00006tus; pdb_00006tuw; pdb_00006tux; pdb_00006vbh; pdb_00007mxq; pdb_00007mxr; pdb_00007mxs; pdb_00007mxt; pdb_00007mxu; pdb_00007mxv; pdb_00007mxw; pdb_00007mxx; pdb_00007qo1; pdb_00008yjh; pdb_00008yjl; pdb_00008yjq; pdb_00008yjr; pdb_00008yjs; pdb_00008yju; pdb_00008yjv; pdb_00008yjw; pdb_00008yjz » more |