PROSITE entry PS00847

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PURL: https://purl.expasy.org/prosite/signature/PS00847

Direct ScanProsite submission

General information about the entry

Entry name [info]	MCM_1
Accession [info]	PS00847
Entry type [info]	PATTERN
Date [info]	01-OCT-1993 CREATED; 01-NOV-1997 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00662

Name and characterization of the entry

Description [info]	MCM family signature.
Pattern [info]	G-[IVT]-[LVAC](2)-[IVT]-D-[DE]-[FL]-[DNST].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.

Total number of hits	96 in 96 different sequences
Number of true positive hits	91 in 91 different sequences
Number of 'unknown' hits	0
Number of false positive hits	5 in 5 different sequences
Number of false negative sequences	21
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	94.79 %
Recall (true positives / (true positives + false negatives))	81.25 %

Comments [info]

Taxonomic range [info]	Archaea, Eukaryotes
Maximum number of repetitions [info]	1
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	91 sequences MC6ZA_XENLA (Q498J7), MC6ZB_XENLA (Q7ZY18), MCM2_ARATH (Q9LPD9), MCM2_DROME (P49735), MCM2_HUMAN (P49736), MCM2_MOUSE (P97310), MCM2_ORYSI (B8BKI8), MCM2_ORYSJ (Q2R482), MCM2_SCHPO (P40377), MCM2_XENLA (P55861), MCM2_XENTR (Q6DIH3), MCM2_YEAST (P29469), MCM31_MAIZE (Q43704), MCM32_MAIZE (Q9SX04), MCM33_MAIZE (Q9SX03), MCM3M_XENLA (P49739), MCM3Z_XENLA (Q7ZXZ0), MCM3Z_XENTR (Q28BS0), MCM3_ARATH (Q9FL33), MCM3_BOVIN (A4FUD9), MCM3_CHICK (Q5ZMN2), MCM3_DROME (Q9XYU1), MCM3_ENTH1 (Q24849), MCM3_HUMAN (P25205), MCM3_MOUSE (P25206), MCM3_ORYSI (B8AZ99), MCM3_ORYSJ (Q0DHC4), MCM3_PONAB (Q5R8G6), MCM3_SCHPO (P30666), MCM3_YEAST (P24279), MCM4A_XENLA (Q5XK83), MCM4B_XENLA (P30664), MCM4_ARATH (Q0WVF5), MCM4_CAEEL (Q95XQ8), MCM4_DROME (Q26454), MCM4_HUMAN (P33991), MCM4_MOUSE (P49717), MCM4_ORYSJ (Q5JKB0), MCM4_SCHPO (P29458), MCM4_XENTR (Q6GL41), MCM4_YEAST (P30665), MCM5A_XENLA (P55862), MCM5B_XENLA (Q6PCI7), MCM5_ARATH (O80786), MCM5_BOVIN (Q0V8B7), MCM5_CAEEL (Q21902), MCM5_DICDI (Q54CP4), MCM5_DROME (Q9VGW6), MCM5_HUMAN (P33992), MCM5_MOUSE (P49718), MCM5_ORYSI (B8AEH3), MCM5_ORYSJ (Q6KAJ4), MCM5_SCHPO (P41389), MCM5_XENTR (Q561P5), MCM5_YEAST (P29496), MCM6M_XENLA (Q5FWY4), MCM6M_XENTR (Q28CM3), MCM6Z_XENTR (Q6P1V8), MCM6_ANOGA (Q7Q0Q1), MCM6_ARATH (F4KAB8), MCM6_BOVIN (Q2KIZ8), MCM6_CAEBR (Q61J08), MCM6_CAEEL (P34647), MCM6_DICDI (Q86B14), MCM6_DROME (Q9V461), MCM6_DROPS (Q29JI9), MCM6_HUMAN (Q14566), MCM6_MOUSE (P97311), MCM6_ORYSI (B8AZX3), MCM6_ORYSJ (Q6F353), MCM6_RAT(Q62724), MCM6_SCHPO (P49731), MCM6_YEAST (P53091), MCM7A_XENLA (Q91876), MCM7B_XENLA (Q7ZXB1), MCM7_ARATH (P43299), MCM7_BOVIN (Q3ZBH9), MCM7_DROME (Q9XYU0), MCM7_HUMAN (P33993), MCM7_MOUSE (Q61881), MCM7_ORYSI (B8BMI1), MCM7_ORYSJ (Q2QNM1), MCM7_SCHPO (O75001), MCM7_XENTR (Q6NX31), MCM7_YEAST (P38132), MCM8_ORYSI (B8AZ14), MCM8_ORYSJ (B9FKM7), Y1489_METJA (Q58884), Y3513_METJA (Q60275), Y363_METJA (Q57809), Y961_METJA (Q58371) » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	21 sequences MCM8_ARATH (Q9SF37), MCM8_BOVIN (E1BPX4), MCM8_CHICK (I0IUP3), MCM8_HUMAN (Q9UJA3), MCM8_MOUSE (Q9CWV1), MCM8_RAT(D3ZVK1), MCM8_XENLA (Q5F310), MCM8_XENTR (Q0V9Q6), MCM9_ARATH (F4IFF3), MCM9_BOVIN (F1N2W9), MCM9_CHICK (I0IUP4), MCM9_DANRE (F1QDI9), MCM9_HUMAN (Q9NXL9), MCM9_MOUSE (Q2KHI9), MCM9_ORYSI (B8B406), MCM9_ORYSJ (Q69QA6), MCM9_RAT(F1M5F3), MCM9_XENLA (Q6NRM6), MCM9_XENTR (F6RIX4), MCMR_DROME (Q9VF30), MCM_SACS2 (Q9UXG1) » more
UniProtKB/Swiss-Prot False positive sequences	5 sequences SMC_MYCPA (Q73VM3), UGPC_BARHE (Q6G5J0), UGPC_BARQU (Q6G194), XGPT_AGRFC (Q8UEM6), XGPT_RHIEC (Q2K9D7) » more
PDB [Detailed view]	78 PDB pdb_00003ja8; pdb_00003jc5; pdb_00003jc6; pdb_00003jc7; pdb_00005bk4; pdb_00005u8s; pdb_00005u8t; pdb_00005v8f; pdb_00005xf8; pdb_00006eyc; pdb_00006f0l; pdb_00006hv9; pdb_00006ptj; pdb_00006ptn; pdb_00006pto; pdb_00006raw; pdb_00006rax; pdb_00006ray; pdb_00006raz; pdb_00006rqc; pdb_00006skl; pdb_00006sko; pdb_00006u0m; pdb_00006wgc; pdb_00006wgf; pdb_00006wgg; pdb_00006wgi; pdb_00006xtx; pdb_00006xty; pdb_00007p30; pdb_00007p5z; pdb_00007pfo; pdb_00007plo; pdb_00007pmk; pdb_00007pmn; pdb_00007pt6; pdb_00007pt7; pdb_00007qhs; pdb_00007v3u; pdb_00007v3v; pdb_00007w1y; pdb_00007w68; pdb_00007w8g; pdb_00007z13; pdb_00008b9a; pdb_00008b9b; pdb_00008b9c; pdb_00008b9d; pdb_00008kg6; pdb_00008kg8; pdb_00008kg9; pdb_00008ouw; pdb_00008p5e; pdb_00008p62; pdb_00008p63; pdb_00008q6o; pdb_00008q6p; pdb_00008rif; pdb_00008rig; pdb_00008rwv; pdb_00008s09; pdb_00008s0a; pdb_00008s0b; pdb_00008s0d; pdb_00008s0e; pdb_00008s0f; pdb_00008w0e; pdb_00008w0f; pdb_00008w0g; pdb_00008w0i; pdb_00008w7m; pdb_00008w7s; pdb_00008xgc; pdb_00009bcx; pdb_00009caq; pdb_00009gjp; pdb_00009gjw; pdb_00009gm5 » more