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PROSITE entry PS00847


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General information about the entry

Entry name [info] MCM_1
Accession [info] PS00847
Entry type [info] PATTERN
Date [info] 01-OCT-1993 CREATED;
01-NOV-1997 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00662

Name and characterization of the entry

Description [info] MCM family signature.
Pattern [info]
G-[IVT]-[LVAC](2)-[IVT]-D-[DE]-[FL]-[DNST].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 96 in 96 different sequences
Number of true positive hits 91 in 91 different sequences
Number of 'unknown' hits 0
Number of false positive hits 5 in 5 different sequences
Number of false negative sequences 21
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 94.79 %
Recall (true positives / (true positives + false negatives)) 81.25 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
91 sequences

MC6ZA_XENLA (Q498J7), MC6ZB_XENLA (Q7ZY18), MCM2_ARATH  (Q9LPD9), 
MCM2_DROME  (P49735), MCM2_HUMAN  (P49736), MCM2_MOUSE  (P97310), 
MCM2_ORYSI  (B8BKI8), MCM2_ORYSJ  (Q2R482), MCM2_SCHPO  (P40377), 
MCM2_XENLA  (P55861), MCM2_XENTR  (Q6DIH3), MCM2_YEAST  (P29469), 
MCM31_MAIZE (Q43704), MCM32_MAIZE (Q9SX04), MCM33_MAIZE (Q9SX03), 
MCM3M_XENLA (P49739), MCM3Z_XENLA (Q7ZXZ0), MCM3Z_XENTR (Q28BS0), 
MCM3_ARATH  (Q9FL33), MCM3_BOVIN  (A4FUD9), MCM3_CHICK  (Q5ZMN2), 
MCM3_DROME  (Q9XYU1), MCM3_ENTH1  (Q24849), MCM3_HUMAN  (P25205), 
MCM3_MOUSE  (P25206), MCM3_ORYSI  (B8AZ99), MCM3_ORYSJ  (Q0DHC4), 
MCM3_PONAB  (Q5R8G6), MCM3_SCHPO  (P30666), MCM3_YEAST  (P24279), 
MCM4A_XENLA (Q5XK83), MCM4B_XENLA (P30664), MCM4_ARATH  (Q0WVF5), 
MCM4_CAEEL  (Q95XQ8), MCM4_DROME  (Q26454), MCM4_HUMAN  (P33991), 
MCM4_MOUSE  (P49717), MCM4_ORYSJ  (Q5JKB0), MCM4_SCHPO  (P29458), 
MCM4_XENTR  (Q6GL41), MCM4_YEAST  (P30665), MCM5A_XENLA (P55862), 
MCM5B_XENLA (Q6PCI7), MCM5_ARATH  (O80786), MCM5_BOVIN  (Q0V8B7), 
MCM5_CAEEL  (Q21902), MCM5_DICDI  (Q54CP4), MCM5_DROME  (Q9VGW6), 
MCM5_HUMAN  (P33992), MCM5_MOUSE  (P49718), MCM5_ORYSI  (B8AEH3), 
MCM5_ORYSJ  (Q6KAJ4), MCM5_SCHPO  (P41389), MCM5_XENTR  (Q561P5), 
MCM5_YEAST  (P29496), MCM6M_XENLA (Q5FWY4), MCM6M_XENTR (Q28CM3), 
MCM6Z_XENTR (Q6P1V8), MCM6_ANOGA  (Q7Q0Q1), MCM6_ARATH  (F4KAB8), 
MCM6_BOVIN  (Q2KIZ8), MCM6_CAEBR  (Q61J08), MCM6_CAEEL  (P34647), 
MCM6_DICDI  (Q86B14), MCM6_DROME  (Q9V461), MCM6_DROPS  (Q29JI9), 
MCM6_HUMAN  (Q14566), MCM6_MOUSE  (P97311), MCM6_ORYSI  (B8AZX3), 
MCM6_ORYSJ  (Q6F353), MCM6_RAT(Q62724), MCM6_SCHPO  (P49731), 
MCM6_YEAST  (P53091), MCM7A_XENLA (Q91876), MCM7B_XENLA (Q7ZXB1), 
MCM7_ARATH  (P43299), MCM7_BOVIN  (Q3ZBH9), MCM7_DROME  (Q9XYU0), 
MCM7_HUMAN  (P33993), MCM7_MOUSE  (Q61881), MCM7_ORYSI  (B8BMI1), 
MCM7_ORYSJ  (Q2QNM1), MCM7_SCHPO  (O75001), MCM7_XENTR  (Q6NX31), 
MCM7_YEAST  (P38132), MCM8_ORYSI  (B8AZ14), MCM8_ORYSJ  (B9FKM7), 
Y1489_METJA (Q58884), Y3513_METJA (Q60275), Y363_METJA  (Q57809), 
Y961_METJA  (Q58371)
» more

UniProtKB/Swiss-Prot
False negative sequences
21 sequences

MCM8_ARATH  (Q9SF37), MCM8_BOVIN  (E1BPX4), MCM8_CHICK  (I0IUP3), 
MCM8_HUMAN  (Q9UJA3), MCM8_MOUSE  (Q9CWV1), MCM8_RAT(D3ZVK1), 
MCM8_XENLA  (Q5F310), MCM8_XENTR  (Q0V9Q6), MCM9_ARATH  (F4IFF3), 
MCM9_BOVIN  (F1N2W9), MCM9_CHICK  (I0IUP4), MCM9_DANRE  (F1QDI9), 
MCM9_HUMAN  (Q9NXL9), MCM9_MOUSE  (Q2KHI9), MCM9_ORYSI  (B8B406), 
MCM9_ORYSJ  (Q69QA6), MCM9_RAT(F1M5F3), MCM9_XENLA  (Q6NRM6), 
MCM9_XENTR  (F6RIX4), MCMR_DROME  (Q9VF30), MCM_SACS2   (Q9UXG1)
» more

UniProtKB/Swiss-Prot
False positive sequences
5 sequences

SMC_MYCPA   (Q73VM3), UGPC_BARHE  (Q6G5J0), UGPC_BARQU  (Q6G194), 
XGPT_AGRFC  (Q8UEM6), XGPT_RHIEC  (Q2K9D7)
» more

PDB
[Detailed view]
60 PDB

3JA8; 3JC5; 3JC6; 3JC7; 5BK4; 5U8S; 5U8T; 5V8F; 5XF8; 6EYC; 6F0L; 6HV9; 6PTJ; 6PTN; 6PTO; 6RAW; 6RAX; 6RAY; 6RAZ; 6RQC; 6SKL; 6SKO; 6U0M; 6WGC; 6WGF; 6WGG; 6WGI; 6XTX; 6XTY; 7P30; 7P5Z; 7PFO; 7PLO; 7PMK; 7PMN; 7PT6; 7PT7; 7QHS; 7V3U; 7V3V; 7W1Y; 7W68; 7W8G; 7Z13; 8B9A; 8B9B; 8B9C; 8B9D; 8KG6; 8KG8; 8KG9; 8OUW; 8P5E; 8P62; 8P63; 8Q6O; 8Q6P; 8W7M; 8W7S; 8XGC
» more