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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS00850


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PURL: https://purl.expasy.org/prosite/signature/PS00850

Direct ScanProsite submission
General information about the entry

Entry name [info] GLY_RADICAL_1
Accession [info] PS00850
Entry type [info] PATTERN
Date [info] 01-OCT-1993 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00665

Name and characterization of the entry

Description [info] Glycine radical domain signature.
Pattern [info] 
[STIV]-x-R-[IVT]-[CSA]-G-Y-{GI}-[GACV].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 131 in 131 different sequences
Number of true positive hits 123 in 123 different sequences
Number of 'unknown' hits 0
Number of false positive hits 8 in 8 different sequences
Number of false negative sequences 9
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 93.89 %
Recall (true positives / (true positives + false negatives)) 93.18 %

Comments [info]

Taxonomic range [info] Bacteriophages, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] radical at position 6
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 123 sequences 

CUTC_OLEA2  (Q30W70), GRCA_ACTP2  (A3MZ79), GRCA_ACTP7  (B3H0M3), 

GRCA_ACTPJ  (B0BTB3), GRCA_ACTSZ  (A6VLV5), GRCA_ALIF1  (Q5E2Y6), 
GRCA_ALIFM  (B5FAJ9), GRCA_ALISL  (B6EKY5), GRCA_BPT4   (P13316), 
GRCA_CITK8  (A8AD08), GRCA_CROS8  (A7MH19), GRCA_ECO24  (A7ZQ24), 
GRCA_ECO27  (B7UH18), GRCA_ECO45  (B7MIR4), GRCA_ECO55  (B7LDH2), 
GRCA_ECO57  (P68067), GRCA_ECO5E  (B5Z153), GRCA_ECO7I  (B7NRN5), 
GRCA_ECO81  (B7MYL2), GRCA_ECO8A  (B7M8J4), GRCA_ECOBW  (C4ZYK2), 
GRCA_ECODH  (B1XBQ6), GRCA_ECOHS  (A8A391), GRCA_ECOK1  (A1AEA9), 
GRCA_ECOL5  (Q0TEQ9), GRCA_ECOL6  (Q8FF10), GRCA_ECOLC  (B1IVP8), 
GRCA_ECOLI  (P68066), GRCA_ECOLU  (B7N6H0), GRCA_ECOSE  (B6I5F4), 
GRCA_ECOSM  (B1LP92), GRCA_EDWI9  (C5BAK4), GRCA_ENT38  (A4WDE8), 
GRCA_ERWT9  (B2VED1), GRCA_ESCF3  (B7LUY6), GRCA_GLAP5  (B8F6C4), 
GRCA_HAEDU  (Q7VMC2), GRCA_HAEI8  (Q4QPM7), GRCA_HAEIE  (A5UBC1), 
GRCA_HAEIG  (A5UFJ0), GRCA_HAEIN  (P44455), GRCA_HISS1  (Q0I272), 
GRCA_HISS2  (B0UWA8), GRCA_KLEP3  (B5XNF9), GRCA_KLEP7  (A6TCJ1), 
GRCA_MANSM  (Q65VN1), GRCA_PASMU  (Q9CPH6), GRCA_PECAS  (Q6D209), 
GRCA_PECCP  (C6DC10), GRCA_PHOPR  (Q6LUP6), GRCA_PROMH  (B4F057), 
GRCA_PSYIN  (A1SUE3), GRCA_SALA4  (B5F227), GRCA_SALAR  (A9MGW0), 
GRCA_SALCH  (Q57L55), GRCA_SALDC  (B5FRD8), GRCA_SALEP  (B5QTW0), 
GRCA_SALG2  (B5RD61), GRCA_SALHS  (B4TE27), GRCA_SALNS  (B4T289), 
GRCA_SALPA  (Q5PLH7), GRCA_SALPB  (A9N0W4), GRCA_SALPC  (C0PVZ1), 
GRCA_SALPK  (B5BAR8), GRCA_SALSV  (B4TS28), GRCA_SALTI  (Q8XFE0), 
GRCA_SALTY  (Q7CQ05), GRCA_SERLI  (P18953), GRCA_SERP5  (A8GI38), 
GRCA_SHIB3  (B2TYK2), GRCA_SHIBS  (Q31XQ5), GRCA_SHIDS  (Q32CU0), 
GRCA_SHIF8  (Q0T1S7), GRCA_SHIFL  (Q83K21), GRCA_SHISS  (Q3YYT6), 
GRCA_VIBA3  (B7VJ50), GRCA_VIBC1  (A7MS83), GRCA_VIBC3  (A5F5R7), 
GRCA_VIBCH  (Q9KPK6), GRCA_VIBCM  (C3LQD3), GRCA_VIBPA  (Q87SC7), 
GRCA_VIBVU  (Q8DEP5), GRCA_VIBVY  (Q7MNR2), GRCA_YERE8  (A1JKI9), 
GRCA_YERP3  (A7FFS5), GRCA_YERPA  (Q1C569), GRCA_YERPB  (B2KA62), 
GRCA_YERPE  (Q8ZD84), GRCA_YERPG  (A9R3Y7), GRCA_YERPN  (Q1CKF7), 
GRCA_YERPP  (A4TKZ1), GRCA_YERPS  (Q667T8), GRCA_YERPY  (B1JRB2), 
GRE1_ECOLI  (P32674), GRE2_ECOLI  (P75793), HPSG_BILW3  (E5Y7I4), 
ISLA_BILW3  (E5Y378), ISLA_DESDA  (B8J0R1), ISLA_NITV2  (Q727N1), 
ISLA_OLEA2  (Q312S2), NRDD_BPT4   (P07071), NRDD_ECOLI  (P28903), 
NRDD_HAEIN  (P43752), NRDD_SALTY  (Q9L646), PFLB_ECOLI  (P09373), 
PFLB_HAEIN  (P43753), PFLB_STAA3  (Q2FK44), PFLB_STAA8  (Q2G1D8), 
PFLB_STAAB  (Q2YV53), PFLB_STAAC  (Q5HJF4), PFLB_STAAM  (Q99WZ7), 
PFLB_STAAN  (Q7A7X6), PFLB_STAAR  (Q6GK90), PFLB_STAAS  (Q6GCQ0), 
PFLB_STAAW  (Q7A1W9), PFLB_STAEQ  (Q5HKH9), PFLB_STAES  (Q8CTX6), 
PFL_CHLRE   (P37836), PFL_CLOPA   (Q46266), PFL_LACLA   (O32797), 
PFL_LACLM   (O32799), PFL_STRMU   (Q59934), TDCE_ECOLI  (P42632)
» more

UniProtKB/Swiss-Prot
False negative sequences		 9 sequences 

BSSA_THAAR  (O87943), HPDL_CLOD6  (Q18CP5), HPDL_CLODC  (C9XIS5), 

HPDL_CLODI  (Q84F16), HPDL_CLODR  (C9YHW1), HPDL_CLOSL  (Q38HX4), 
HPFG_KLEOX  (A0A318FL05), HYPD_CLODI  (A0A031WDE4), IAD_TRASO   (A0A100YXA1)
» more

UniProtKB/Swiss-Prot
False positive sequences		 8 sequences 

AGLB1_ARCFU (O29918), AROB_THEFY  (Q47QY7), MAGI3_HUMAN (Q5TCQ9), 

PURA_PICTO  (Q6L2M3), VRTB_PENAE  (D7PHZ3), WHITE_LUCCU (Q05360), 
WRN_CAEEL   (Q19546), YR034_MIMIV (Q5UPB0)
» more

PDB
[Detailed view]		 22 PDB

pdb_00001cm5; pdb_00001h16; pdb_00001h17; pdb_00001h18; pdb_00001mzo; pdb_00002pfl; pdb_00003pfl; pdb_00005fau; pdb_00005fav; pdb_00005faw; pdb_00005fay; pdb_00005kdp; pdb_00005ymr; pdb_00006lon; pdb_00006nd3; pdb_00006owr; pdb_00006vue; pdb_00007kq3; pdb_00007kq4; pdb_00008id7; pdb_00008yjn; pdb_00008yjo
» more