PROSITE logo

PROSITE entry PS00860


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] GTP_CYCLOHYDROL_1_2
Accession [info] PS00860
Entry type [info] PATTERN
Date [info] 01-OCT-1993 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00672

Name and characterization of the entry

Description [info] GTP cyclohydrolase I signature 2.
Pattern [info] 
[SA]-x-[RK]-x-Q-[LIVMT]-Q-E-[RNAK]-[LIM]-[TSNV].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_06 which contains 572'619 sequence entries.


Total number of hits 310 in 310 different sequences
Number of true positive hits 308 in 308 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 65
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 99.35 %
Recall (true positives / (true positives + false negatives)) 82.57 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 308 sequences 

GCH11_NOSS1 (Q8YLL1), GCH11_PSEAE (Q9HYG8), GCH11_PSEPK (Q88LV4), 

GCH11_PSESM (Q887V1), GCH12_NOSS1 (Q8YN49), GCH12_PSEAE (Q9I351), 
GCH12_PSEPK (Q88JY1), GCH12_PSESM (Q884Q3), GCH1_AERHH  (A0KIN6), 
GCH1_AERS4  (A4SPE8), GCH1_ALIF1  (Q5E4E4), GCH1_ALIFM  (B5FF36), 
GCH1_ALISL  (B6EGN8), GCH1_ALKEH  (Q0A939), GCH1_AQUAE  (O66603), 
GCH1_AZOVD  (C1DHG2), GCH1_BACAA  (C3P598), GCH1_BACAC  (C3L8S8), 
GCH1_BACAH  (A0RBW5), GCH1_BACAN  (Q81SW2), GCH1_BACC0  (B7JGZ6), 
GCH1_BACC1  (Q73AY4), GCH1_BACC2  (B7IP89), GCH1_BACC3  (C1EN08), 
GCH1_BACC4  (B7HHR5), GCH1_BACC7  (B7HL21), GCH1_BACCN  (A7GN48), 
GCH1_BACCQ  (B9IVN3), GCH1_BACCR  (Q81FQ8), GCH1_BACCZ  (Q63DM1), 
GCH1_BACFN  (Q5L925), GCH1_BACFR  (Q64P85), GCH1_BACHK  (Q6HL44), 
GCH1_BACMK  (A9VMC0), GCH1_BACP2  (A8FEL2), GCH1_BACSU  (P19465), 
GCH1_BACTN  (Q8A0U0), GCH1_BACVZ  (A7Z630), GCH1_BARHE  (Q6G3J8), 
GCH1_BAUCH  (Q1LT77), GCH1_BEII9  (B2IBC4), GCH1_BIFLD  (B3DR12), 
GCH1_BIFLO  (Q8G3S1), GCH1_BLOFL  (Q7VRX3), GCH1_BLOPB  (Q492J7), 
GCH1_BREBN  (C0ZCC7), GCH1_BUCAP  (Q8KA05), GCH1_CAEEL  (Q19980), 
GCH1_CALS4  (Q8R7N2), GCH1_CARHZ  (Q3ADI2), GCH1_CHESB  (Q11JM4), 
GCH1_CHICK  (P50141), GCH1_CHLCH  (Q3ATN0), GCH1_CHLPM  (A4SF37), 
GCH1_CHLTE  (Q8KEA8), GCH1_CHRSD  (Q1QV64), GCH1_CITK8  (A8AE79), 
GCH1_CLOD6  (Q18BW7), GCH1_CLOK1  (B9E092), GCH1_CLOK5  (A5N6S3), 
GCH1_CLONN  (A0Q2L7), GCH1_CLOP1  (Q0TRM0), GCH1_CLOPE  (Q8XLM2), 
GCH1_CLOPS  (Q0STY9), GCH1_CORA7  (C3PJE8), GCH1_COREF  (Q8FMG3), 
GCH1_CORGB  (A4QH94), GCH1_CORGL  (Q8NM84), GCH1_COXBN  (A9KFF3), 
GCH1_COXBR  (A9NDB3), GCH1_COXBU  (Q83DE3), GCH1_DEIRA  (Q9RYB4), 
GCH1_DESRM  (A4J5D0), GCH1_DICDI  (Q94465), GCH1_DROME  (P48596), 
GCH1_ECO24  (A7ZNX6), GCH1_ECO27  (B7UFG9), GCH1_ECO45  (B7MF66), 
GCH1_ECO55  (B7LAH4), GCH1_ECO57  (P0A6T7), GCH1_ECO5E  (B5YWU3), 
GCH1_ECO7I  (B7NMB8), GCH1_ECO81  (B7MXG6), GCH1_ECO8A  (B7M4Z9), 
GCH1_ECOBW  (C4ZU03), GCH1_ECODH  (B1X7P1), GCH1_ECOHS  (A8A214), 
GCH1_ECOK1  (A1AD13), GCH1_ECOL5  (Q0TFT7), GCH1_ECOL6  (P0A6T6), 
GCH1_ECOLC  (B1IYB6), GCH1_ECOLI  (P0A6T5), GCH1_ECOLU  (B7NCI3), 
GCH1_ECOSE  (B6I8K3), GCH1_ECOSM  (B1LKQ0), GCH1_ECOUT  (Q1R9R9), 
GCH1_EDWI9  (C5BCL9), GCH1_ENT38  (A4WCI8), GCH1_ERWT9  (B2VII2), 
GCH1_ESCF3  (B7LVB3), GCH1_EUGGR  (P51597), GCH1_FINM2  (B0S1R1), 
GCH1_FLAJ1  (A5FHM7), GCH1_FUSNN  (Q8RH43), GCH1_GEOKA  (Q5KXT7), 
GCH1_GEOSW  (C5D3E8), GCH1_GLOVI  (Q7NK98), GCH1_HAEI8  (Q4QKH4), 
GCH1_HAEIE  (A5UC59), GCH1_HAEIG  (A5UEW4), GCH1_HAEIN  (P43866), 
GCH1_HAHCH  (Q2SPJ2), GCH1_HALH5  (Q9KCC7), GCH1_HAMD5  (C4K3L4), 
GCH1_HELAH  (Q17WX5), GCH1_HELP2  (B6JME9), GCH1_HELPG  (B5Z7T2), 
GCH1_HELPH  (Q1CSU6), GCH1_HELPJ  (Q9ZKS2), GCH1_HELPS  (B2UU76), 
GCH1_HELPY  (P56462), GCH1_HISS1  (Q0I3F6), GCH1_HISS2  (B0UUA9), 
GCH1_HUMAN  (P30793), GCH1_HYDS0  (B4U640), GCH1_HYPBU  (A2BL58), 
GCH1_JANMA  (A6SZ52), GCH1_KLEP3  (B5XP57), GCH1_KLEP7  (A6TBN8), 
GCH1_LEIXX  (Q6ACQ1), GCH1_LEPBA  (B0S8X8), GCH1_LEPBJ  (Q04P36), 
GCH1_LEPBL  (Q056J8), GCH1_LEPBP  (B0SRX6), GCH1_LEPIC  (Q72LY8), 
GCH1_LEPIN  (Q8EYG1), GCH1_LISIN  (Q92A75), GCH1_LISMC  (C1KWN3), 
GCH1_LISMF  (Q71Y82), GCH1_LISMH  (B8DBZ3), GCH1_LISMO  (Q8Y5X1), 
GCH1_LISW6  (A0AK45), GCH1_LYSSC  (B1HTA3), GCH1_MANSM  (Q65TR0), 
GCH1_METCA  (Q607T5), GCH1_MOUSE  (Q05915), GCH1_MUCPU  (P51598), 
GCH1_MYCA1  (A0QA85), GCH1_MYCA9  (B1MGU9), GCH1_MYCBO  (P64208), 
GCH1_MYCBP  (A1KPU4), GCH1_MYCBT  (C1AI67), GCH1_MYCGI  (A4T5P2), 
GCH1_MYCLB  (B8ZU42), GCH1_MYCLE  (O69531), GCH1_MYCMM  (B2HJ53), 
GCH1_MYCPA  (Q743Z2), GCH1_MYCTA  (A5U8T4), GCH1_MYCTO  (P9WN56), 
GCH1_MYCTU  (P9WN57), GCH1_MYCUA  (A0PV57), GCH1_MYCVP  (A1TG42), 
GCH1_NEUCR  (P51599), GCH1_NITMU  (Q2Y6B3), GCH1_NOSP7  (B2J1L7), 
GCH1_ONCMY  (P51596), GCH1_OSTOS  (O61573), GCH1_PARD8  (A6LFE8), 
GCH1_PASMU  (P57865), GCH1_PECAS  (Q6D3N3), GCH1_PECCP  (C6DEM6), 
GCH1_PELTS  (A5D2D8), GCH1_PELUB  (Q4FL89), GCH1_PERMH  (C0QPU5), 
GCH1_PHOLL  (Q7N6K7), GCH1_PHOPR  (Q6LQL4), GCH1_PHYBL  (P51600), 
GCH1_PORG3  (B2RIJ1), GCH1_PORGI  (Q7MWI5), GCH1_RAT(P22288), 
GCH1_RHILO  (Q98LQ6), GCH1_RHIME  (Q92QB4), GCH1_RHOBA  (Q7UJJ7), 
GCH1_RICAE  (C3PNA0), GCH1_RICAH  (A8GN89), GCH1_RICB8  (A8GUB6), 
GCH1_RICBR  (Q1RID0), GCH1_RICCN  (Q92I93), GCH1_RICFE  (Q4ULX3), 
GCH1_RICM5  (A8F1F2), GCH1_RICPR  (Q9ZDE8), GCH1_RICPU  (C4K2D8), 
GCH1_RICRO  (B0BXB8), GCH1_RICRS  (A8GRW0), GCH1_RICTY  (Q68WZ4), 
GCH1_SACS2  (Q980E8), GCH1_SALA4  (B5EYP3), GCH1_SALAR  (A9MK63), 
GCH1_SALCH  (Q57ME6), GCH1_SALDC  (B5FNJ7), GCH1_SALEP  (B5R163), 
GCH1_SALG2  (B5RC32), GCH1_SALHS  (B4TAL5), GCH1_SALNS  (B4SY26), 
GCH1_SALPA  (Q5PE52), GCH1_SALPB  (A9N6K0), GCH1_SALPC  (C0Q0U7), 
GCH1_SALPK  (B5BE43), GCH1_SALSV  (B4TNQ0), GCH1_SALTI  (P64210), 
GCH1_SALTY  (P64209), GCH1_SCHPO  (O13774), GCH1_SERP5  (A8GC24), 
GCH1_SHEAM  (A1S2C7), GCH1_SHEB2  (B8E4J0), GCH1_SHEB5  (A3CZJ1), 
GCH1_SHEB8  (A6WIA1), GCH1_SHEB9  (A9KXZ9), GCH1_SHEDO  (Q12SG0), 
GCH1_SHELP  (A3QIQ4), GCH1_SHEON  (Q8E9L6), GCH1_SHEPC  (A4Y2K7), 
GCH1_SHESA  (A0L1S4), GCH1_SHESM  (Q0HE51), GCH1_SHESR  (Q0HZU8), 
GCH1_SHESW  (A1REU0), GCH1_SHIB3  (B2TVT9), GCH1_SHIBS  (Q31YW1), 
GCH1_SHIDS  (Q32EN8), GCH1_SHIF8  (Q0T2X1), GCH1_SHIFL  (P0A6T8), 
GCH1_SHISS  (Q3Z053), GCH1_SINFN  (C3MB45), GCH1_SINMW  (A6U8C2), 
GCH1_SODGM  (Q2NUE3), GCH1_STRA1  (Q3K0Y1), GCH1_STRA3  (Q8E549), 
GCH1_STRA5  (Q8DZI5), GCH1_STRAW  (Q82EE8), GCH1_STRCO  (Q9X8I3), 
GCH1_STRGC  (A8AZD8), GCH1_STRGG  (B1VSG4), GCH1_STRMU  (Q8DUG2), 
GCH1_STRP1  (P0C0C2), GCH1_STRP2  (Q04MF9), GCH1_STRP3  (P0DB30), 
GCH1_STRP4  (B5E6W5), GCH1_STRP6  (Q5XCA9), GCH1_STRP7  (C1CB65), 
GCH1_STRP8  (P0A3E9), GCH1_STRPG  (A2REL9), GCH1_STRPI  (B1I918), 
GCH1_STRPJ  (B8ZL26), GCH1_STRPN  (P51595), GCH1_STRPQ  (P0DB31), 
GCH1_STRPS  (B2ISL9), GCH1_STRPY  (P0C0C1), GCH1_STRPZ  (B5XLE8), 
GCH1_STRR6  (P59656), GCH1_STRS2  (A4W1S9), GCH1_STRSV  (A3CKF4), 
GCH1_STRSY  (A4VVH1), GCH1_STRT1  (Q5LYM8), GCH1_STRT2  (Q5M391), 
GCH1_STRZJ  (C1CC81), GCH1_STRZP  (C1CIH2), GCH1_STRZT  (C1CPG4), 
GCH1_SULAC  (Q4J8S2), GCH1_SULIA  (C3MZ97), GCH1_SULIK  (C4KIH5), 
GCH1_SULIL  (C3MR62), GCH1_SULIM  (C3MXF1), GCH1_SULIN  (C3NGB7), 
GCH1_SULIY  (C3N7B7), GCH1_SULSY  (B2V9P4), GCH1_SULTO  (Q971G9), 
GCH1_SYNE7  (Q54769), GCH1_SYNJA  (Q2JR69), GCH1_SYNJB  (Q2JPT8), 
GCH1_SYNP6  (Q5N623), GCH1_SYNY3  (Q55759), GCH1_THEFY  (Q47KU5), 
GCH1_THEP3  (B0KCE5), GCH1_THEPX  (B0K5C1), GCH1_THEVB  (Q8DJB8), 
GCH1_THEYD  (B5YJV0), GCH1_TOLAT  (C4LDE6), GCH1_VIBC1  (A7N6L2), 
GCH1_VIBCH  (Q9KLX5), GCH1_VIBPA  (Q87GZ6), GCH1_VIBVU  (Q8D6I7), 
GCH1_VIBVY  (Q7MDE5), GCH1_WIGBR  (Q8D2N7), GCH1_WOLSU  (Q7M933), 
GCH1_XANAC  (Q8PEP3), GCH1_XANCP  (Q8P3B0), GCH1_XANE5  (Q3BM80), 
GCH1_XYLF2  (B2I4L2), GCH1_XYLFA  (Q9PC02), GCH1_XYLFM  (B0U794), 
GCH1_XYLFT  (Q87D63), GCH1_YEAST  (P51601), GCH1_YERE8  (A1JU09), 
GCH1_YERP3  (A7FJL1), GCH1_YERPB  (B2JZ02), GCH1_YERPE  (Q8ZG15), 
GCH1_YERPG  (A9R1B1), GCH1_YERPY  (B1JQJ4)
» more

UniProtKB/Swiss-Prot
False negative sequences		 65 sequences 

FOLKE_LACLA (Q9CGE3), FOLKE_LACLM (Q8GJP4), GCH1_ACET2  (A3DHH6), 

GCH1_ACTP2  (A3N0R3), GCH1_ACTP7  (B3GXP9), GCH1_ACTPJ  (B0BPI8), 
GCH1_AGRFC  (Q8UEK8), GCH1_ALLAM  (B9JWF1), GCH1_AZOC5  (A8HUG2), 
GCH1_BARBK  (A1USJ5), GCH1_BARQU  (Q6FZZ4), GCH1_BRADU  (Q89IW2), 
GCH1_BRUA1  (B2S5T0), GCH1_BRUA2  (Q2YQ03), GCH1_BRUA4  (A6X0X0), 
GCH1_BRUAB  (Q57D61), GCH1_BRUC2  (A9M586), GCH1_BRUMB  (C0RJ47), 
GCH1_BRUME  (Q8YH94), GCH1_BRUO2  (A5VQL0), GCH1_BRUSI  (B0CGM4), 
GCH1_BRUSU  (Q8G0L4), GCH1_CALMQ  (A8MC60), GCH1_CAMC1  (A7ZB36), 
GCH1_CAMC5  (A7GW42), GCH1_CAMJ8  (A8FJZ5), GCH1_CAMJD  (A7H1R1), 
GCH1_CAMJE  (P51594), GCH1_CAMJJ  (A1VXS2), GCH1_CAMJR  (Q5HWX4), 
GCH1_CAMLR  (B9KDZ8), GCH1_CAUVC  (Q9AAY3), GCH1_CHRVO  (Q7NYZ2), 
GCH1_CLOAB  (Q97D54), GCH1_CLOB1  (A7FU67), GCH1_CLOB6  (C3KVW3), 
GCH1_CLOB8  (A6LWG6), GCH1_CLOBH  (A5I231), GCH1_CLOBJ  (C1FN26), 
GCH1_CLOBK  (B1IL94), GCH1_CLOBL  (A7GDP1), GCH1_CLOBM  (B1L1S1), 
GCH1_DEHM1  (Q3Z782), GCH1_DEHMB  (A5FQD3), GCH1_DEHMC  (Q3ZYB5), 
GCH1_ENTFA  (Q82Z12), GCH1_HAEDU  (Q7VM90), GCH1_HELHP  (Q7VFG4), 
GCH1_HYPNA  (Q0BXB5), GCH1_LACPL  (Q88ST4), GCH1_LATSS  (Q38WN0), 
GCH1_MARMM  (Q0AM02), GCH1_METS4  (B0U881), GCH1_PSEA6  (Q15YG1), 
GCH1_PSET1  (Q3IF89), GCH1_PYRAE  (Q8ZWW5), GCH1_PYRNV  (B1YCT7), 
GCH1_RALN1  (Q8XZK8), GCH1_RHOP2  (Q2IY20), GCH1_RHOPA  (Q6N4E7), 
GCH1_RHOPB  (Q212N0), GCH1_RHOPS  (Q134L7), GCH1_RHOPT  (B3QE25), 
GCH1_RUMCH  (B8I184), GCH1_TERTT  (C5BL73)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

GCH1_BACPU  (P48063)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			2 sequences
			


			
EME2_XENTR  (Q0IHN5), HOT_DROME   (Q9W265)


				
	

	

		PDB
[Detailed view]		
		
			23 PDB
			


			1A8R; 1A9C; 1FB1; 1FBX; 1GTP; 1IS7; 1IS8; 1N3R; 1N3S; 1N3T; 1WPL; 4DU6; 
			
				4UQF; 6Z80; 6Z85; 6Z86; 6Z87; 6Z88; 6Z89; 7ALA; 7ALB; 7ALC; 7ALQ
			
			

			» more