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PROSITE entry PS00860


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General information about the entry

Entry name [info] GTP_CYCLOHYDROL_1_2
Accession [info] PS00860
Entry type [info] PATTERN
Date [info] 01-OCT-1993 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00672

Name and characterization of the entry

Description [info] GTP cyclohydrolase I signature 2.
Pattern [info] 
[SA]-x-[RK]-x-Q-[LIVMT]-Q-E-[RNAK]-[LIM]-[TSNV].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 310 in 310 different sequences
Number of true positive hits 308 in 308 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 65
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 99.35 %
Recall (true positives / (true positives + false negatives)) 82.57 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 308 sequences 

GCH11_NOSS1 (Q8YLL1), GCH11_PSEAE (Q9HYG8), GCH11_PSEPK (Q88LV4), 

GCH11_PSESM (Q887V1), GCH12_NOSS1 (Q8YN49), GCH12_PSEAE (Q9I351), 
GCH12_PSEPK (Q88JY1), GCH12_PSESM (Q884Q3), GCH1_AERHH  (A0KIN6), 
GCH1_AERS4  (A4SPE8), GCH1_ALIF1  (Q5E4E4), GCH1_ALIFM  (B5FF36), 
GCH1_ALISL  (B6EGN8), GCH1_ALKEH  (Q0A939), GCH1_AQUAE  (O66603), 
GCH1_AZOVD  (C1DHG2), GCH1_BACAA  (C3P598), GCH1_BACAC  (C3L8S8), 
GCH1_BACAH  (A0RBW5), GCH1_BACAN  (Q81SW2), GCH1_BACC0  (B7JGZ6), 
GCH1_BACC1  (Q73AY4), GCH1_BACC2  (B7IP89), GCH1_BACC3  (C1EN08), 
GCH1_BACC4  (B7HHR5), GCH1_BACC7  (B7HL21), GCH1_BACCN  (A7GN48), 
GCH1_BACCQ  (B9IVN3), GCH1_BACCR  (Q81FQ8), GCH1_BACCZ  (Q63DM1), 
GCH1_BACFN  (Q5L925), GCH1_BACFR  (Q64P85), GCH1_BACHK  (Q6HL44), 
GCH1_BACMK  (A9VMC0), GCH1_BACP2  (A8FEL2), GCH1_BACSU  (P19465), 
GCH1_BACTN  (Q8A0U0), GCH1_BACVZ  (A7Z630), GCH1_BARHE  (Q6G3J8), 
GCH1_BAUCH  (Q1LT77), GCH1_BEII9  (B2IBC4), GCH1_BIFLD  (B3DR12), 
GCH1_BIFLO  (Q8G3S1), GCH1_BLOFL  (Q7VRX3), GCH1_BLOPB  (Q492J7), 
GCH1_BREBN  (C0ZCC7), GCH1_BUCAP  (Q8KA05), GCH1_CAEEL  (Q19980), 
GCH1_CALS4  (Q8R7N2), GCH1_CARHZ  (Q3ADI2), GCH1_CHESB  (Q11JM4), 
GCH1_CHICK  (P50141), GCH1_CHLCH  (Q3ATN0), GCH1_CHLPM  (A4SF37), 
GCH1_CHLTE  (Q8KEA8), GCH1_CHRSD  (Q1QV64), GCH1_CITK8  (A8AE79), 
GCH1_CLOD6  (Q18BW7), GCH1_CLOK1  (B9E092), GCH1_CLOK5  (A5N6S3), 
GCH1_CLONN  (A0Q2L7), GCH1_CLOP1  (Q0TRM0), GCH1_CLOPE  (Q8XLM2), 
GCH1_CLOPS  (Q0STY9), GCH1_CORA7  (C3PJE8), GCH1_COREF  (Q8FMG3), 
GCH1_CORGB  (A4QH94), GCH1_CORGL  (Q8NM84), GCH1_COXBN  (A9KFF3), 
GCH1_COXBR  (A9NDB3), GCH1_COXBU  (Q83DE3), GCH1_DEIRA  (Q9RYB4), 
GCH1_DESRM  (A4J5D0), GCH1_DICDI  (Q94465), GCH1_DROME  (P48596), 
GCH1_ECO24  (A7ZNX6), GCH1_ECO27  (B7UFG9), GCH1_ECO45  (B7MF66), 
GCH1_ECO55  (B7LAH4), GCH1_ECO57  (P0A6T7), GCH1_ECO5E  (B5YWU3), 
GCH1_ECO7I  (B7NMB8), GCH1_ECO81  (B7MXG6), GCH1_ECO8A  (B7M4Z9), 
GCH1_ECOBW  (C4ZU03), GCH1_ECODH  (B1X7P1), GCH1_ECOHS  (A8A214), 
GCH1_ECOK1  (A1AD13), GCH1_ECOL5  (Q0TFT7), GCH1_ECOL6  (P0A6T6), 
GCH1_ECOLC  (B1IYB6), GCH1_ECOLI  (P0A6T5), GCH1_ECOLU  (B7NCI3), 
GCH1_ECOSE  (B6I8K3), GCH1_ECOSM  (B1LKQ0), GCH1_ECOUT  (Q1R9R9), 
GCH1_EDWI9  (C5BCL9), GCH1_ENT38  (A4WCI8), GCH1_ERWT9  (B2VII2), 
GCH1_ESCF3  (B7LVB3), GCH1_EUGGR  (P51597), GCH1_FINM2  (B0S1R1), 
GCH1_FLAJ1  (A5FHM7), GCH1_FUSNN  (Q8RH43), GCH1_GEOKA  (Q5KXT7), 
GCH1_GEOSW  (C5D3E8), GCH1_GLOVI  (Q7NK98), GCH1_HAEI8  (Q4QKH4), 
GCH1_HAEIE  (A5UC59), GCH1_HAEIG  (A5UEW4), GCH1_HAEIN  (P43866), 
GCH1_HAHCH  (Q2SPJ2), GCH1_HALH5  (Q9KCC7), GCH1_HAMD5  (C4K3L4), 
GCH1_HELAH  (Q17WX5), GCH1_HELP2  (B6JME9), GCH1_HELPG  (B5Z7T2), 
GCH1_HELPH  (Q1CSU6), GCH1_HELPJ  (Q9ZKS2), GCH1_HELPS  (B2UU76), 
GCH1_HELPY  (P56462), GCH1_HISS1  (Q0I3F6), GCH1_HISS2  (B0UUA9), 
GCH1_HUMAN  (P30793), GCH1_HYDS0  (B4U640), GCH1_HYPBU  (A2BL58), 
GCH1_JANMA  (A6SZ52), GCH1_KLEP3  (B5XP57), GCH1_KLEP7  (A6TBN8), 
GCH1_LEIXX  (Q6ACQ1), GCH1_LEPBA  (B0S8X8), GCH1_LEPBJ  (Q04P36), 
GCH1_LEPBL  (Q056J8), GCH1_LEPBP  (B0SRX6), GCH1_LEPIC  (Q72LY8), 
GCH1_LEPIN  (Q8EYG1), GCH1_LISIN  (Q92A75), GCH1_LISMC  (C1KWN3), 
GCH1_LISMF  (Q71Y82), GCH1_LISMH  (B8DBZ3), GCH1_LISMO  (Q8Y5X1), 
GCH1_LISW6  (A0AK45), GCH1_LYSSC  (B1HTA3), GCH1_MANSM  (Q65TR0), 
GCH1_METCA  (Q607T5), GCH1_MOUSE  (Q05915), GCH1_MUCPU  (P51598), 
GCH1_MYCA1  (A0QA85), GCH1_MYCA9  (B1MGU9), GCH1_MYCBO  (P64208), 
GCH1_MYCBP  (A1KPU4), GCH1_MYCBT  (C1AI67), GCH1_MYCGI  (A4T5P2), 
GCH1_MYCLB  (B8ZU42), GCH1_MYCLE  (O69531), GCH1_MYCMM  (B2HJ53), 
GCH1_MYCPA  (Q743Z2), GCH1_MYCTA  (A5U8T4), GCH1_MYCTO  (P9WN56), 
GCH1_MYCTU  (P9WN57), GCH1_MYCUA  (A0PV57), GCH1_MYCVP  (A1TG42), 
GCH1_NEUCR  (P51599), GCH1_NITMU  (Q2Y6B3), GCH1_NOSP7  (B2J1L7), 
GCH1_ONCMY  (P51596), GCH1_OSTOS  (O61573), GCH1_PARD8  (A6LFE8), 
GCH1_PASMU  (P57865), GCH1_PECAS  (Q6D3N3), GCH1_PECCP  (C6DEM6), 
GCH1_PELTS  (A5D2D8), GCH1_PELUB  (Q4FL89), GCH1_PERMH  (C0QPU5), 
GCH1_PHOLL  (Q7N6K7), GCH1_PHOPR  (Q6LQL4), GCH1_PHYBL  (P51600), 
GCH1_PORG3  (B2RIJ1), GCH1_PORGI  (Q7MWI5), GCH1_RAT(P22288), 
GCH1_RHILO  (Q98LQ6), GCH1_RHIME  (Q92QB4), GCH1_RHOBA  (Q7UJJ7), 
GCH1_RICAE  (C3PNA0), GCH1_RICAH  (A8GN89), GCH1_RICB8  (A8GUB6), 
GCH1_RICBR  (Q1RID0), GCH1_RICCN  (Q92I93), GCH1_RICFE  (Q4ULX3), 
GCH1_RICM5  (A8F1F2), GCH1_RICPR  (Q9ZDE8), GCH1_RICPU  (C4K2D8), 
GCH1_RICRO  (B0BXB8), GCH1_RICRS  (A8GRW0), GCH1_RICTY  (Q68WZ4), 
GCH1_SACS2  (Q980E8), GCH1_SALA4  (B5EYP3), GCH1_SALAR  (A9MK63), 
GCH1_SALCH  (Q57ME6), GCH1_SALDC  (B5FNJ7), GCH1_SALEP  (B5R163), 
GCH1_SALG2  (B5RC32), GCH1_SALHS  (B4TAL5), GCH1_SALNS  (B4SY26), 
GCH1_SALPA  (Q5PE52), GCH1_SALPB  (A9N6K0), GCH1_SALPC  (C0Q0U7), 
GCH1_SALPK  (B5BE43), GCH1_SALSV  (B4TNQ0), GCH1_SALTI  (P64210), 
GCH1_SALTY  (P64209), GCH1_SCHPO  (O13774), GCH1_SERP5  (A8GC24), 
GCH1_SHEAM  (A1S2C7), GCH1_SHEB2  (B8E4J0), GCH1_SHEB5  (A3CZJ1), 
GCH1_SHEB8  (A6WIA1), GCH1_SHEB9  (A9KXZ9), GCH1_SHEDO  (Q12SG0), 
GCH1_SHELP  (A3QIQ4), GCH1_SHEON  (Q8E9L6), GCH1_SHEPC  (A4Y2K7), 
GCH1_SHESA  (A0L1S4), GCH1_SHESM  (Q0HE51), GCH1_SHESR  (Q0HZU8), 
GCH1_SHESW  (A1REU0), GCH1_SHIB3  (B2TVT9), GCH1_SHIBS  (Q31YW1), 
GCH1_SHIDS  (Q32EN8), GCH1_SHIF8  (Q0T2X1), GCH1_SHIFL  (P0A6T8), 
GCH1_SHISS  (Q3Z053), GCH1_SINFN  (C3MB45), GCH1_SINMW  (A6U8C2), 
GCH1_SODGM  (Q2NUE3), GCH1_STRA1  (Q3K0Y1), GCH1_STRA3  (Q8E549), 
GCH1_STRA5  (Q8DZI5), GCH1_STRAW  (Q82EE8), GCH1_STRCO  (Q9X8I3), 
GCH1_STRGC  (A8AZD8), GCH1_STRGG  (B1VSG4), GCH1_STRMU  (Q8DUG2), 
GCH1_STRP1  (P0C0C2), GCH1_STRP2  (Q04MF9), GCH1_STRP3  (P0DB30), 
GCH1_STRP4  (B5E6W5), GCH1_STRP6  (Q5XCA9), GCH1_STRP7  (C1CB65), 
GCH1_STRP8  (P0A3E9), GCH1_STRPG  (A2REL9), GCH1_STRPI  (B1I918), 
GCH1_STRPJ  (B8ZL26), GCH1_STRPN  (P51595), GCH1_STRPQ  (P0DB31), 
GCH1_STRPS  (B2ISL9), GCH1_STRPY  (P0C0C1), GCH1_STRPZ  (B5XLE8), 
GCH1_STRR6  (P59656), GCH1_STRS2  (A4W1S9), GCH1_STRSV  (A3CKF4), 
GCH1_STRSY  (A4VVH1), GCH1_STRT1  (Q5LYM8), GCH1_STRT2  (Q5M391), 
GCH1_STRZJ  (C1CC81), GCH1_STRZP  (C1CIH2), GCH1_STRZT  (C1CPG4), 
GCH1_SULAC  (Q4J8S2), GCH1_SULIA  (C3MZ97), GCH1_SULIK  (C4KIH5), 
GCH1_SULIL  (C3MR62), GCH1_SULIM  (C3MXF1), GCH1_SULIN  (C3NGB7), 
GCH1_SULIY  (C3N7B7), GCH1_SULSY  (B2V9P4), GCH1_SULTO  (Q971G9), 
GCH1_SYNE7  (Q54769), GCH1_SYNJA  (Q2JR69), GCH1_SYNJB  (Q2JPT8), 
GCH1_SYNP6  (Q5N623), GCH1_SYNY3  (Q55759), GCH1_THEFY  (Q47KU5), 
GCH1_THEP3  (B0KCE5), GCH1_THEPX  (B0K5C1), GCH1_THEVB  (Q8DJB8), 
GCH1_THEYD  (B5YJV0), GCH1_TOLAT  (C4LDE6), GCH1_VIBC1  (A7N6L2), 
GCH1_VIBCH  (Q9KLX5), GCH1_VIBPA  (Q87GZ6), GCH1_VIBVU  (Q8D6I7), 
GCH1_VIBVY  (Q7MDE5), GCH1_WIGBR  (Q8D2N7), GCH1_WOLSU  (Q7M933), 
GCH1_XANAC  (Q8PEP3), GCH1_XANCP  (Q8P3B0), GCH1_XANE5  (Q3BM80), 
GCH1_XYLF2  (B2I4L2), GCH1_XYLFA  (Q9PC02), GCH1_XYLFM  (B0U794), 
GCH1_XYLFT  (Q87D63), GCH1_YEAST  (P51601), GCH1_YERE8  (A1JU09), 
GCH1_YERP3  (A7FJL1), GCH1_YERPB  (B2JZ02), GCH1_YERPE  (Q8ZG15), 
GCH1_YERPG  (A9R1B1), GCH1_YERPY  (B1JQJ4)
» more

UniProtKB/Swiss-Prot
False negative sequences		 65 sequences 

FOLKE_LACLA (Q9CGE3), FOLKE_LACLM (Q8GJP4), GCH1_ACET2  (A3DHH6), 

GCH1_ACTP2  (A3N0R3), GCH1_ACTP7  (B3GXP9), GCH1_ACTPJ  (B0BPI8), 
GCH1_AGRFC  (Q8UEK8), GCH1_ALLAM  (B9JWF1), GCH1_AZOC5  (A8HUG2), 
GCH1_BARBK  (A1USJ5), GCH1_BARQU  (Q6FZZ4), GCH1_BRADU  (Q89IW2), 
GCH1_BRUA1  (B2S5T0), GCH1_BRUA2  (Q2YQ03), GCH1_BRUA4  (A6X0X0), 
GCH1_BRUAB  (Q57D61), GCH1_BRUC2  (A9M586), GCH1_BRUMB  (C0RJ47), 
GCH1_BRUME  (Q8YH94), GCH1_BRUO2  (A5VQL0), GCH1_BRUSI  (B0CGM4), 
GCH1_BRUSU  (Q8G0L4), GCH1_CALMQ  (A8MC60), GCH1_CAMC1  (A7ZB36), 
GCH1_CAMC5  (A7GW42), GCH1_CAMJ8  (A8FJZ5), GCH1_CAMJD  (A7H1R1), 
GCH1_CAMJE  (P51594), GCH1_CAMJJ  (A1VXS2), GCH1_CAMJR  (Q5HWX4), 
GCH1_CAMLR  (B9KDZ8), GCH1_CAUVC  (Q9AAY3), GCH1_CHRVO  (Q7NYZ2), 
GCH1_CLOAB  (Q97D54), GCH1_CLOB1  (A7FU67), GCH1_CLOB6  (C3KVW3), 
GCH1_CLOB8  (A6LWG6), GCH1_CLOBH  (A5I231), GCH1_CLOBJ  (C1FN26), 
GCH1_CLOBK  (B1IL94), GCH1_CLOBL  (A7GDP1), GCH1_CLOBM  (B1L1S1), 
GCH1_DEHM1  (Q3Z782), GCH1_DEHMB  (A5FQD3), GCH1_DEHMC  (Q3ZYB5), 
GCH1_ENTFA  (Q82Z12), GCH1_HAEDU  (Q7VM90), GCH1_HELHP  (Q7VFG4), 
GCH1_HYPNA  (Q0BXB5), GCH1_LACPL  (Q88ST4), GCH1_LATSS  (Q38WN0), 
GCH1_MARMM  (Q0AM02), GCH1_METS4  (B0U881), GCH1_PSEA6  (Q15YG1), 
GCH1_PSET1  (Q3IF89), GCH1_PYRAE  (Q8ZWW5), GCH1_PYRNV  (B1YCT7), 
GCH1_RALN1  (Q8XZK8), GCH1_RHOP2  (Q2IY20), GCH1_RHOPA  (Q6N4E7), 
GCH1_RHOPB  (Q212N0), GCH1_RHOPS  (Q134L7), GCH1_RHOPT  (B3QE25), 
GCH1_RUMCH  (B8I184), GCH1_TERTT  (C5BL73)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

GCH1_BACPU  (P48063)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			2 sequences
			


			
EME2_XENTR  (Q0IHN5), HOT_DROME   (Q9W265)


				
	

	

		PDB
[Detailed view]		
		
			23 PDB
			


			1A8R; 1A9C; 1FB1; 1FBX; 1GTP; 1IS7; 1IS8; 1N3R; 1N3S; 1N3T; 1WPL; 4DU6; 
			
				4UQF; 6Z80; 6Z85; 6Z86; 6Z87; 6Z88; 6Z89; 7ALA; 7ALB; 7ALC; 7ALQ
			
			

			» more