PROSITE logo

PROSITE entry PS00865


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00865
Entry name [info] UBIQUITIN_ACTIVAT_2
Accession [info] PS00865
Entry type [info] PATTERN
Date [info] 01-OCT-1993 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00463
Associated ProRule [info] PRU10132

Name and characterization of the entry

Description [info] Ubiquitin-activating enzyme active site.
Pattern [info] 
P-[LIVMG]-C-T-[LIVM]-[KRHA]-x-[FTNM]-P.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 36 in 36 different sequences
Number of true positive hits 36 in 36 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 3
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 92.31 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] active_site at position 3
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 36 sequences 

SAE2A_XENLA (Q642Q1), SAE2B_XENLA (Q7ZY60), SAE2_CAEEL  (Q9NAN1), 

SAE2_DANRE  (Q7SXG4), SAE2_HUMAN  (Q9UBT2), SAE2_MOUSE  (Q9Z1F9), 
SAE2_XENTR  (Q28GH3), UBA1Y_MOUSE (P31254), UBA1_BOVIN  (A3KMV5), 
UBA1_CANAW  (P52495), UBA1_DICDI  (Q55C16), UBA1_HUMAN  (P22314), 
UBA1_MOUSE  (Q02053), UBA1_RABIT  (Q29504), UBA1_RAT(Q5U300), 
UBA1_SCHPO  (O94609), UBA1_YEAST  (P22515), UBA2_SCHPO  (O42939), 
UBA2_YEAST  (P52488), UBA3_ARATH  (O65041), UBA3_CAEEL  (Q19360), 
UBA3_DANRE  (Q7ZVX6), UBA3_DROME  (Q9V6U8), UBA3_HUMAN  (Q8TBC4), 
UBA3_MOUSE  (Q8C878), UBA3_PONAB  (Q5R4A0), UBA3_RAT(Q99MI7), 
UBA3_SCHPO  (Q09765), UBA3_YEAST  (Q99344), UBA7_HUMAN  (P41226), 
UBE11_ARATH (P93028), UBE11_WHEAT (P20973), UBE12_ARATH (P92974), 
UBE12_WHEAT (P31251), UBE13_WHEAT (P31252), UBE1Y_OSPRU (P31255)
» more

UniProtKB/Swiss-Prot
False negative sequences		 3 sequences 

UBA3_DICDI  (Q54QG9), UBA6_HUMAN  (A0AVT1), UBA6_MOUSE  (Q8C7R4)


				
	

	

		PDB
[Detailed view]		
		
			58 PDB
			


			1TT5; 1YOV; 1Z7L; 2NVU; 2PX9; 3CMM; 3GZN; 3KYC; 3KYD; 4II2; 4II3; 4NNJ; 
			
				5KNL; 5L6H; 5L6I; 5L6J; 5TR4; 6CWY; 6CWZ; 6NYA; 6O82; 6O83; 6XOG; 6XOH; 
				6XOI; 6ZHS; 6ZHT; 6ZHU; 6ZQH; 7K5J; 7ZH9; 8OIF; 8SE9; 8SEA; 8SEB; 8SV8; 
				9B5C; 9B5D; 9B5E; 9B5F; 9B5G; 9B5H; 9B5I; 9B5J; 9B5K; 9B5L; 9B5M; 9B5N; 
				9B5O; 9B5P; 9B5Q; 9B5R; 9B5S; 9B5T; 9B5U; 9B5V; 9B5W; 9B5X
			
			

			» more