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PROSITE entry PS00866


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00866
Entry name [info] CPSASE_1
Accession [info] PS00866
Entry type [info] PATTERN
Date [info] 01-OCT-1993 CREATED;
01-JUL-1998 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00676

Name and characterization of the entry

Description [info] Carbamoyl-phosphate synthase subdomain signature 1.
Pattern [info] 
[FYV]-[PS]-[LIVMC]-[LIVMA]-[LIVM]-[KR]-[PSA]-[STA]-x(3)-[SG]-G-x-[AG].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 502 in 311 different sequences
Number of true positive hits 501 in 310 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 25
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 99.80 %
Recall (true positives / (true positives + false negatives)) 95.25 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 310 sequences 

2OCS_HYDTT  (D3DJ42), ACACA_BOVIN (Q9TTS3), ACACA_HUMAN (Q13085), 

ACACA_MOUSE (Q5SWU9), ACACA_RAT   (P11497), ACACA_SHEEP (Q28559), 
ACACB_HUMAN (O00763), ACACB_MOUSE (E9Q4Z2), ACAC_CHICK  (P11029), 
ACAC_SCHPO  (P78820), ACAC_YEAST  (Q00955), ACCA1_MYCBO (P0A509), 
ACCA1_MYCTO (P9WPQ2), ACCA1_MYCTU (P9WPQ3), ACCA3_MYCLE (P46392), 
ACCC1_BACSU (P49787), ACCC1_POPTR (B9HBA8), ACCC2_BACSU (O34544), 
ACCC2_POPTR (B9N843), ACCC_ALLVD  (O52058), ACCC_ARATH  (O04983), 
ACCC_ECO57  (Q8X9B6), ACCC_ECOLI  (P24182), ACCC_HAEIN  (P43873), 
ACCC_HALH5  (Q9KDS9), ACCC_NOSS1  (Q06862), ACCC_PSEAE  (P37798), 
CARB1_AQUAE (O67869), CARB1_METJA (Q58773), CARB1_METKA (Q8TWX0), 
CARB2_AQUAE (O67233), CARB2_METJA (Q58776), CARB2_METKA (Q8TUT7), 
CARB_ACIC5  (C1F1S6), CARB_AGARV  (C4ZEK2), CARB_AGRFC  (Q8UDE9), 
CARB_ARATH  (Q42601), CARB_ARCFU  (O28994), CARB_ARTS2  (A0JX72), 
CARB_BACAA  (C3P656), CARB_BACAC  (C3L740), CARB_BACAH  (A0RHQ8), 
CARB_BACAN  (Q81WF2), CARB_BACC0  (B7JJX3), CARB_BACC1  (Q732I3), 
CARB_BACC2  (B7IUP6), CARB_BACC3  (C1EPQ0), CARB_BACC4  (B7H6M2), 
CARB_BACC7  (B7HLM0), CARB_BACCL  (P46537), CARB_BACCN  (A7GRL1), 
CARB_BACCQ  (B9IVW3), CARB_BACCR  (Q819S3), CARB_BACCZ  (Q636E0), 
CARB_BACHK  (Q6HES8), CARB_BACMK  (A9VTC6), CARB_BACSU  (P25994), 
CARB_BEUC1  (C5C687), CARB_BIFA0  (B8DTW3), CARB_BIFAA  (A1A0T4), 
CARB_BIFLD  (B3DQ32), CARB_BIFLO  (Q8G815), CARB_BIFLS  (B7GPW2), 
CARB_BRUME  (Q8YIC2), CARB_BRUSU  (Q8FZJ3), CARB_BUCAI  (P57244), 
CARB_BUCAP  (Q8K9Z7), CARB_CALS4  (Q8RBK0), CARB_CAMJE  (Q9PIL7), 
CARB_CLAM3  (A5CRX5), CARB_CLASE  (B0REV9), CARB_CLOAB  (Q97FT3), 
CARB_CLOB8  (A6LPD9), CARB_CLOBA  (B2UX86), CARB_CLOBB  (B2THH3), 
CARB_CLOBJ  (C1FNY3), CARB_CLOBL  (A7GE89), CARB_CLOBM  (B1KT07), 
CARB_CLOP1  (Q0TM79), CARB_CLOPE  (Q8XHB3), CARB_CLOPS  (Q0SPY4), 
CARB_COREF  (Q8FT42), CARB_CORGL  (P58939), CARB_CUTAK  (Q6A914), 
CARB_CUTCT  (P46056), CARB_DEIGD  (Q1IWM0), CARB_DESAP  (B1I4M8), 
CARB_ECO57  (P63737), CARB_ECOL6  (Q8FLB0), CARB_ECOLI  (P00968), 
CARB_ENTFA  (Q834E2), CARB_EREGS  (Q75D66), CARB_EXIS2  (B1YIR9), 
CARB_EXISA  (C4L5W3), CARB_FUSNN  (Q8RG86), CARB_GEMAT  (C1A4I5), 
CARB_GEOSE  (O50302), CARB_HAEDU  (Q7VP67), CARB_HALER  (Q8RSS3), 
CARB_HALH5  (Q9K9V9), CARB_HALOH  (B8D1H3), CARB_HALSA  (Q9HP43), 
CARB_HYPBU  (A2BJL3), CARB_KINRD  (A6WCC6), CARB_KOCRD  (B2GI87), 
CARB_KORVE  (Q1IPK2), CARB_LACAC  (Q5FJC0), CARB_LACCB  (B3WEF5), 
CARB_LACDB  (Q047M8), CARB_LACH4  (A8YVZ3), CARB_LACJO  (Q74J34), 
CARB_LACLA  (Q9CFV2), CARB_LACLM  (O32771), CARB_LACLS  (Q02YG5), 
CARB_LACP3  (Q038Z2), CARB_LACP7  (A9KI94), CARB_LACPL  (P77886), 
CARB_LATSS  (Q38X24), CARB_LEPIC  (Q72NF1), CARB_LEPIN  (Q8F832), 
CARB_LEUCK  (B1MZ74), CARB_LEUMM  (Q03WW7), CARB_LIGS1  (Q1WVA9), 
CARB_LIMF3  (B2GD06), CARB_LIMRD  (A5VHN6), CARB_LIMRJ  (B2G564), 
CARB_LISIN  (Q92AH3), CARB_LISMC  (C1KWD4), CARB_LISMF  (Q71YI1), 
CARB_LISMH  (B8DDR7), CARB_LISMO  (Q8Y665), CARB_LISW6  (A0AJU0), 
CARB_LYSSC  (B1HQC1), CARB_MACCJ  (B9EB69), CARB_METAC  (Q8TNY4), 
CARB_METB6  (A7I6J1), CARB_METBA  (P13258), CARB_METBF  (Q469Z7), 
CARB_METHJ  (Q2FLD9), CARB_METLZ  (A2SQ53), CARB_METMA  (P58944), 
CARB_METMJ  (A3CU73), CARB_METPE  (B8GEA3), CARB_METS3  (A5UKG5), 
CARB_METTH  (O27077), CARB_METTP  (A0B8K9), CARB_MICLC  (C5CCF1), 
CARB_MYCBO  (Q7U054), CARB_MYCGI  (A4TBY6), CARB_MYCLE  (Q9CCR2), 
CARB_MYCSJ  (A3PZ65), CARB_MYCSK  (A1UFK4), CARB_MYCSS  (Q1B9F9), 
CARB_MYCTO  (P9WPK2), CARB_MYCTU  (P9WPK3), CARB_MYCVP  (A1T8H1), 
CARB_MYXXD  (Q1D6Y8), CARB_NATTJ  (B2A170), CARB_NEIGO  (Q59599), 
CARB_NEIMA  (Q9JW02), CARB_NEIMB  (Q9JXW8), CARB_NEUCR  (Q7SH52), 
CARB_NOSS1  (Q8YQL2), CARB_OENOB  (Q04H29), CARB_ORYSJ  (B9EXM2), 
CARB_PAEAT  (A1R6Z3), CARB_PASMU  (Q9CKV0), CARB_PEDPA  (Q03HB0), 
CARB_PELTS  (A5D508), CARB_PSEAE  (P38100), CARB_PSECP  (B8H8U5), 
CARB_PSELT  (A8F453), CARB_PSEPK  (Q88DU6), CARB_PSESM  (Q87WP4), 
CARB_PYRFU  (Q8U085), CARB_RALN1  (Q8XZ83), CARB_RENSM  (A9WSA8), 
CARB_RHILO  (Q98I87), CARB_RHIME  (Q92PZ4), CARB_RUBXD  (Q1AVY9), 
CARB_SALTI  (Q8Z9L7), CARB_SALTY  (P14846), CARB_SCHPO  (O94313), 
CARB_SHIFL  (P63738), CARB_STAA1  (A7X1F4), CARB_STAA2  (A6U122), 
CARB_STAA3  (Q2FHN5), CARB_STAA8  (Q2FZ72), CARB_STAA9  (A5IS88), 
CARB_STAAB  (Q2YXG5), CARB_STAAC  (Q5HGM9), CARB_STAAE  (A6QGA4), 
CARB_STAAM  (P63739), CARB_STAAN  (P63740), CARB_STAAR  (Q6GHN2), 
CARB_STAAS  (Q6GA10), CARB_STAAT  (A8Z3P0), CARB_STAAW  (P58940), 
CARB_STACT  (B9DPN2), CARB_STAEQ  (Q5HPY8), CARB_STAES  (Q8CPJ4), 
CARB_STAHJ  (Q4L5Q5), CARB_STAS1  (Q49WY4), CARB_STRA1  (Q3K150), 
CARB_STRA3  (Q8E5F5), CARB_STRA5  (Q8DZQ7), CARB_STRAW  (Q827Q7), 
CARB_STRCO  (Q9KXR6), CARB_STRE4  (C0M756), CARB_STRGC  (A8AX83), 
CARB_STRGG  (B1W463), CARB_STRMU  (Q8DUP3), CARB_STRP1  (Q9A0C6), 
CARB_STRP2  (Q04K48), CARB_STRP3  (P0DA14), CARB_STRP4  (B5E512), 
CARB_STRP6  (Q5XCR6), CARB_STRP7  (C1C7Q3), CARB_STRP8  (P58941), 
CARB_STRPG  (A2RF60), CARB_STRPI  (B1IC65), CARB_STRPJ  (B8ZJT9), 
CARB_STRPN  (Q97QE4), CARB_STRPQ  (P0DA15), CARB_STRPS  (B2IQ67), 
CARB_STRPZ  (B5XKW2), CARB_STRR6  (Q8CWR0), CARB_STRS7  (C0MEH1), 
CARB_STRSV  (A3CNI5), CARB_STRT1  (Q5M0W9), CARB_STRT2  (Q5M5F6), 
CARB_STRTD  (Q03LT8), CARB_STRU0  (B9DRV7), CARB_STRZJ  (C1CEM9), 
CARB_STRZP  (C1CL09), CARB_STRZT  (C1CR31), CARB_SULAC  (Q4J8E8), 
CARB_SULTO  (Q970U7), CARB_SYMTH  (Q67Q54), CARB_SYNY3  (Q55756), 
CARB_THEMA  (Q9WZ27), CARB_THENN  (B9KB91), CARB_THEP1  (A5IJL8), 
CARB_THEP3  (B0KBW4), CARB_THEPX  (B0K4D7), CARB_THERP  (B9KXM5), 
CARB_THESQ  (B1L8T8), CARB_THET2  (P96495), CARB_THET8  (Q5SKN1), 
CARB_VIBCH  (Q9KPH9), CARB_VIBPA  (Q87SF3), CARB_VIBVU  (Q8DEM2), 
CARB_VIBVY  (Q7MNU0), CARB_XANAC  (P58942), CARB_XANCP  (P58943), 
CARB_XYLFA  (Q9PEC1), CARB_XYLFT  (Q87EB8), CARB_YEAST  (P03965), 
CARB_YERPE  (Q8ZIL4), CARB_ZYMMO  (O50236), CARY_BACSU  (P18185), 
CARY_GEOSE  (Q9ZB63), CARY_HALH5  (Q9K8V7), CARY_LACPL  (Q9RLS9), 
CPSM_AQUCT  (Q91293), CPSM_HUMAN  (P31327), CPSM_MOUSE  (Q8C196), 
CPSM_RAT(P07756), DMXL1_CRYX8 (A0A4P8DJE6), DUR1_LACKL  (A5H0J2), 
DUR1_YEAST  (P32528), HFA1_YEAS1  (B3LM95), HFA1_YEAS2  (C7GRE4), 
HFA1_YEAS7  (A6ZMR9), HFA1_YEAS8  (C8ZF72), HFA1_YEAST  (P32874), 
LAMA_EMENI  (P38095), MCCA_ARATH  (Q42523), MCCA_ORYSJ  (Q2QMG2), 
MCCA_SOYBN  (Q42777), PCCA_CAEBR  (Q612F5), PCCA_CAEEL  (Q19842), 
PCCA_HUMAN  (P05165), PCCA_MOUSE  (Q91ZA3), PCCA_PIG(P0DTA4), 
PCCA_RAT(P14882), PCCA_RUEPO  (Q5LUF3), PYC1_YEAST  (P11154), 
PYC2_YEAST  (P32327), PYCA_ARCFU  (O30019), PYCA_METJA  (Q58626), 
PYCA_METTH  (O27939), PYC_ASPNG   (Q9HES8), PYC_ASPTE   (O93918), 
PYC_ASPTN   (Q0CLK1), PYC_BACSU   (Q9KWU4), PYC_PICAN   (Q8X1T3), 
PYC_PICPA   (P78992), PYC_STAAM   (A0A0H3JRU9), PYR1_CAEEL  (Q18990), 
PYR1_DICDI  (P20054), PYR1_DROME  (P05990), PYR1_EMENI  (O93937), 
PYR1_HUMAN  (P27708), PYR1_MESAU  (P08955), PYR1_MOUSE  (B2RQC6), 
PYR1_NEUCR  (Q7S8A6), PYR1_SCHPO  (Q09794), PYR1_SQUAC  (Q91437), 
PYR1_YEAST  (P07259)
» more

UniProtKB/Swiss-Prot
False negative sequences		 25 sequences 

ACAC_DICDI  (Q54J08), ACC1_ARATH  (Q38970), ACC1_ORYSJ  (Q8S6N5), 

ACC2_ARATH  (F4I1L3), ACC2_ORYSJ  (B9FK36), ACCA3_MYCTU (P96890), 
CARB_BUCBP  (P59448), CARB_CAUVC  (Q9A4D6), CARB_DEIDV  (C1CXR4), 
CARB_DEIRA  (Q9RWK0), CARB_HELPJ  (Q9ZKT2), CARB_HELPY  (O25577), 
CARB_PYRAE  (Q8ZY48), CARB_RHOBA  (Q7UJ58), CARB_SACS2  (Q59969), 
CARB_SULIA  (C3N664), CARB_SULIK  (C4KHM7), CARB_SULIL  (C3MQE3), 
CARB_SULIM  (C3MW21), CARB_SULIN  (C3NH23), CARB_SULIY  (C3NEM0), 
CARB_THEAC  (Q9HK17), CARB_THEVO  (Q97AJ3), MCCA_RAT(Q5I0C3), 
PYC1_CAEEL  (O17732)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

ACCC_POPEU  (P84546)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			1 sequence
			


			
PURT_DECAR  (Q47A50)


				
	

	

		PDB
[Detailed view]		
		
			89 PDB
			


			1A9X; 1BNC; 1BXR; 1C30; 1C3O; 1CE8; 1CS0; 1DV1; 1DV2; 1JDB; 1KEE; 1M6V; 
			
				1T36; 1W93; 1W96; 2C00; 2CQY; 2GPS; 2GPW; 2HJW; 2J9G; 2V58; 2V59; 2V5A; 
				2VQD; 2VR1; 2W6M; 2W6N; 2W6O; 2W6P; 2W6Q; 2W6Z; 2W70; 2W71; 2YL2; 3BG5; 
				3G8C; 3G8D; 3GID; 3GLK; 3HB9; 3HBL; 3HO8; 3JRW; 3JRX; 3JZF; 3JZI; 3N6R; 
				3RUP; 3RV3; 3RV4; 4HNT; 4HNU; 4HNV; 4HQ6; 4HR7; 4MV1; 4MV3; 4MV4; 4MV6; 
				4MV7; 4MV8; 4MV9; 4RZQ; 5CSK; 5CSL; 5DOT; 5DOU; 5KKN; 6G2D; 6G2H; 6G2I; 
				6OI8; 6OI9; 6OJH; 6UEL; 6W2J; 7KBL; 7KC7; 7KCT; 7YBU; 8UZ2; 8XKZ; 8XL0; 
				8XL1; 8XL2; 8XL3; 8XL4; 8XL5
			
			

			» more