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PROSITE entry PS00868


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PURL: https://purl.expasy.org/prosite/signature/PS00868

Direct ScanProsite submission
General information about the entry

Entry name [info] CYS_MET_METAB_PP
Accession [info] PS00868
Entry type [info] PATTERN
Date [info] 01-OCT-1993 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00677

Name and characterization of the entry

Description [info] Cys/Met metabolism enzymes pyridoxal-phosphate attachment site.
Pattern [info] 
[DQ]-[LIVMFY]-x(3)-[STAGCN]-[STAGCIL]-T-K-[FYWQI]-[LIVMF]-x-G-[HQD]-
[SGNH].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 63 in 63 different sequences
Number of true positive hits 63 in 63 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 12
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 84.00 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] pyridoxal_phosphate at position 6
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 63 sequences 

ALGLR_THEMA (Q9X0Z7), CANGL_PSECO (P0DXC4), CANGL_RHILW (P0DXD3), 

CBL_MIMPU   (A0A0M3VI47), CBL_NEUCR   (Q1K8G0), CBL_SCHPO   (O94350), 
CGL2_CAEEL  (P55216), CGL_HUMAN   (P32929), CGL_MACFA   (Q60HG7), 
CGL_MOUSE   (Q8VCN5), CGL_PIG (Q19QT7), CGL_RAT (P18757), 
CGS1_ARATH  (P55217), CGS1_TOBAC  (Q9ZPL5), CGS2_ARATH  (Q9C876), 
CYS3_YEAST  (P31373), CYSA_STRCO  (Q59829), CYSD_EMENI  (P50125), 
CYSD_KLULA  (Q92441), CYSD_SCHPO  (O13326), CYSD_YEAST  (P06106), 
FUB7_FUSO4  (A0A0D2YG02), FUB7_GIBF5  (S0DUX5), FUB7_GIBM7  (W7MS09), 
LOLC1_EPIUN (Q8J0B2), LOLC2_EPIUN (Q5MNH8), MCCB_BACSU  (O05394), 
MEGL_FUSNN  (Q8RDT4), MEGL_PORGI  (Q7MX71), MEGL_PSEDM  (A0A0J6G7P5), 
MEGL_PSEPU  (P13254), MEGL_TREDE  (Q73KL7), MET7_SCHPO  (O74314), 
MET7_YEAST  (P47164), METB_ECOLI  (P00935), METB_HAEIN  (P44502), 
METB_HELPJ  (Q9ZMW7), METB_HELPX  (Q1M0P5), METB_HELPY  (P56069), 
METB_HERAU  (P24601), METB_MYCBO  (P66876), METB_MYCLE  (P46807), 
METB_MYCTO  (P9WGB6), METB_MYCTU  (P9WGB7), METC_ARATH  (P53780), 
METC_BACSU  (O31632), METC_BORAV  (Q07703), METC_COXBU  (Q83A83), 
METC_ECOLI  (P06721), METC_HAEIN  (P44527), METC_LACLA  (P0A4K2), 
METC_LACLC  (P0C2T9), METC_LACLM  (A2RM21), METC_SALTY  (P18949), 
METC_STAHJ  (Q4L332), METC_YEAST  (P43623), METI_BACSU  (O31631), 
METY_LEPME  (P94890), METY_THEMA  (Q9WZY4), METZ_PSEAE  (P55218), 
STR3_YEAST  (P53101), YFHE_SCHPO  (O42851), YHR2_YEAST  (P38716)
» more

UniProtKB/Swiss-Prot
False negative sequences		 12 sequences 

ALGLR_WOLPM (Q73GL9), BESB_STREN  (G8XHD7), IBOG1_AMAMK (A0A0C2WKN7), 

IBOG2_AMAMK (A0A0C2S258), MEGL_FUSNP  (Q8L0X4), MEGL_STRAW  (Q826W3), 
METC_RHIJ3  (Q52811), METZ_MYCTO  (P9WGB4), METZ_MYCTU  (P9WGB5), 
MGL_ARATH   (Q9SGU9), MIMOS_LEULE (A8CEI3), MIMOS_MIMPU (U6BYK3)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

METC_PAPLA  (P85217)


				
	

	

		PDB
[Detailed view]		
		
			50 PDB
			


			1CL1; 1CL2; 1CS1; 1GC0; 1GC2; 1I41; 1I43; 1I48; 1IBJ; 1N8P; 1PG8; 1QGN; 
			
				1UKJ; 2FQ6; 2GQN; 2NMP; 2O7C; 3COG; 3ELP; 3VK2; 3VK3; 3VK4; 4ITG; 4ITX; 
				4L0O; 5EIG; 5TSU; 5TT2; 5X2V; 5X2W; 5X2X; 5X2Y; 5X2Z; 5X30; 6LXU; 6NBA; 
				6OVG; 7BQW; 7F1P; 7F1U; 7F1V; 7KB0; 7KB1; 7YEO; 8EQW; 8ERB; 8ERJ; 8J6N; 
				8OVH; 9IZ5
			
			

			» more