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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
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Amos Bairoch

PROSITE entry PS00876


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PURL: https://purl.expasy.org/prosite/signature/PS00876

Direct ScanProsite submission
General information about the entry

Entry name [info] IDO_1
Accession [info] PS00876
Entry type [info] PATTERN
Date [info] 01-OCT-1993 CREATED;
01-NOV-1995 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00684

Name and characterization of the entry

Description [info] Indoleamine 2,3-dioxygenase signature 1.
Pattern [info] 
G-G-S-[AN]-[GA]-Q-S-S-x(2)-Q.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 11 in 11 different sequences
Number of true positive hits 10 in 10 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 3
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 90.91 %
Recall (true positives / (true positives + false negatives)) 76.92 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 10 sequences 

ACDA_ASPCN  (A0A2I2F272), I23O1_HUMAN (P14902), I23O1_MOUSE (P28776), 

I23O1_RAT   (Q9ERD9), I23O_YEAST  (P47125), MYG_HALDV   (Q01966), 
MYG_HALMK   (P51537), NANC_ASPNN  (A0A6G9KIF9), QULI_PENCI  (P0DUR8), 
TPZB_ASPTN  (Q0CG33)
» more

UniProtKB/Swiss-Prot
False negative sequences		 3 sequences 

I23O2_HUMAN (Q6ZQW0), I23O2_MOUSE (Q8R0V5), I23O2_RAT   (F1LV46)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			1 sequence
			


			
PER_DRONE   (P91686)


				
	

	

		PDB
[Detailed view]		
		
			75 PDB
			


			pdb_00002d0t; pdb_00002d0u; pdb_00004pk5; pdb_00004pk6; pdb_00004u72; pdb_00005ek2; pdb_00005ek3; pdb_00005ek4; pdb_00005etw; pdb_00005whr; pdb_00005wmu; pdb_00005wmv; 
			
				pdb_00005wmw; pdb_00005wmx; pdb_00005wn8; pdb_00005xe1; pdb_00006azu; pdb_00006azv; pdb_00006azw; pdb_00006cxu; pdb_00006cxv; pdb_00006dpq; pdb_00006dpr; pdb_00006e35; 
				pdb_00006e40; pdb_00006e41; pdb_00006e42; pdb_00006e43; pdb_00006e44; pdb_00006e45; pdb_00006e46; pdb_00006f0a; pdb_00006kof; pdb_00006kps; pdb_00006kw7; pdb_00006mq6; 
				pdb_00006o3i; pdb_00006pu7; pdb_00006pz1; pdb_00006r63; pdb_00006ubp; pdb_00006v52; pdb_00006wjy; pdb_00006wpe; pdb_00006x5y; pdb_00007a62; pdb_00007ah4; pdb_00007ah5; 
				pdb_00007ah6; pdb_00007b1o; pdb_00007e0o; pdb_00007e0p; pdb_00007e0q; pdb_00007e0s; pdb_00007e0t; pdb_00007e0u; pdb_00007m63; pdb_00007m7d; pdb_00007nge; pdb_00007p0n; 
				pdb_00007p0r; pdb_00007rrb; pdb_00007rrc; pdb_00007rrd; pdb_00007yxt; pdb_00007z2l; pdb_00007zv3; pdb_00008abx; pdb_00008fur; pdb_00008i7l; pdb_00008u5i; pdb_00009esb; 
				pdb_00009esc; pdb_00009ese; pdb_00009esg
			
			

			» more