PROSITE entry PS00892

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS00892
Entry name [info]	HIT_1
Accession [info]	PS00892
Entry type [info]	PATTERN
Date [info]	01-OCT-1993 CREATED; 01-APR-2006 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00694

Name and characterization of the entry

Description [info]	HIT domain signature.
Pattern [info]	[NQAR]-x(4)-[GSAVY]-x-[QFLPA]-x-[LIVMY]-x-[HWYRQ]-[LIVMFYST]-H-[LIVMFT]- H-[LIVMF]-[LIVMFPT]-[PSGAWN].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	87 in 87 different sequences
Number of true positive hits	87 in 87 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	12
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	87.88 %

Comments [info]

Taxonomic range [info]	Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Version [info]	2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

87 sequences

APH1_SCHPO  (P49776), APTX_BOVIN  (Q7YRZ2), APTX_CANLF  (P61797),

APTX_CHICK  (P61798), APTX_CIOIN  (P61802), APTX_DANRE  (P61799), 
APTX_DROME  (Q8MSG8), APTX_HUMAN  (Q7Z2E3), APTX_MACFA  (Q9BGQ0), 
APTX_MOUSE  (Q7TQC5), APTX_PIG(Q7YRZ1), APTX_RAT(Q8K4H4), 
APTX_TAKRU  (P61800), APTX_XENLA  (Q7T287), APTX_XENTR  (P61801), 
BH140_ARATH (Q9M041), DCPS_BOVIN  (Q8MJJ7), DCPS_HUMAN  (Q96C86), 
DCPS_MOUSE  (Q9DAR7), DCPS_PIG(Q8MIZ3), DCPS_RAT(Q8K4F7), 
DCPS_YEAST  (Q06151), DCS2_YEAST  (Q12123), FHIT_ARATH  (F4KEV7), 
FHIT_BOVIN  (Q1KZG4), FHIT_DICDI  (Q86KK2), FHIT_HUMAN  (P49789), 
FHIT_MOUSE  (O89106), FHIT_RAT(Q9JIX3), HINT1_ARATH (Q8GUN2), 
HINT1_BOVIN (P62958), HINT1_HUMAN (P49773), HINT1_MOUSE (P70349), 
HINT1_PONAB (Q5RF69), HINT1_RABIT (P80912), HINT1_RAT   (P62959), 
HINT2_BOVIN (Q8SQ21), HINT2_HUMAN (Q9BX68), HINT2_MOUSE (Q9D0S9), 
HINT3_ARATH (F4K1R2), HINT_CAEEL  (P53795), HINT_ECO57  (P0ACE8), 
HINT_ECOLI  (P0ACE7), HINT_HAEIN  (P44956), HINT_SHIFL  (P0ACE9), 
HITA_NEIGO  (O07817), HIT_BACSU   (O07513), HIT_ENTH1   (C4LYI2), 
HNT1_CANAL  (Q59WG0), HNT1_SCHPO  (O94586), HNT1_YEAST  (Q04344), 
HNT2_YEAS1  (B3LFZ1), HNT2_YEAS2  (C7GQV5), HNT2_YEAS6  (B5VGI4), 
HNT2_YEAS7  (A6ZYQ3), HNT2_YEAS8  (C8Z5L6), HNT2_YEAST  (P49775), 
NFT1_CAEEL  (O76463), NFT1_DROME  (O76464), PKIA_DICDI  (Q23921), 
Y1390_SYNE7 (P32084), Y664_CHLMU  (Q9PK09), Y866_METJA  (Q58276), 
YHI1_MYCBO  (P0A5B6), YHI1_MYCLE  (P49774), YHI1_MYCTO  (P9WML2), 
YHI1_MYCTU  (P9WML3), YHI2_MYCTO  (P9WML0), YHI2_MYCTU  (P9WML1), 
YHIT_AQUAE  (O66536), YHIT_AZOBR  (P26724), YHIT_BORBU  (P94252), 
YHIT_BUCAI  (P57438), YHIT_BUCAP  (Q8K9I9), YHIT_BUCBP  (Q89AG5), 
YHIT_CHLPN  (Q9Z863), YHIT_CHLTR  (O84390), YHIT_HELPJ  (P64383), 
YHIT_HELPY  (P64382), YHIT_MESHY  (P32083), YHIT_MYCGE  (P47378), 
YHIT_MYCPN  (P75504), YHIT_RICPR  (Q9ZDL1), YHIT_SACS2  (P95937), 
YHIT_SYNY3  (P73481), ZB14_BRAJU  (P42855), ZB14_MAIZE  (P42856)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

12 sequences

AP4A_MYCTO  (P9WMK8), AP4A_MYCTU  (P9WMK9), APTX_YEAST  (Q08702),

HINT3_BOVIN (Q2YDJ4), HINT3_DANRE (Q5PNN8), HINT3_HUMAN (Q9NQE9), 
HINT3_MOUSE (Q9CPS6), HINT3_PONAB (Q5R9L4), HINT3_RAT   (Q8K3P7), 
HINT3_XENTR (Q28BZ2), HINT4_ARATH (Q84VV6), Y2839_DICDI (Q558W0)

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PDB
[Detailed view]

96 PDB

1AV5; 1EMS; 1FHI; 1FIT; 1KPA; 1KPB; 1KPC; 1KPE; 1KPF; 1RZY; 1VLR; 1XML; 1XMM; 1Y23; 2FIT; 3BL7; 3BL9; 3BLA; 3FIT; 3N1S; 3O1C; 3O1X; 3O1Z; 3OJ7; 3OMF; 3OXK; 3QGZ; 3RHN; 3TW2; 4EQE; 4EQG; 4EQH; 4FIT; 4INC; 4INI; 4NDF; 4NDG; 4NDH; 4NDI; 4QDE; 4QDV; 4QEB; 4RHN; 4ZGL; 4ZKL; 4ZKV; 5ED3; 5EMT; 5FIT; 5I2E; 5I2F; 5IPD; 5IPE; 5KLZ; 5KM0; 5KM1; 5KM2; 5KM3; 5KM4; 5KM5; 5KM8; 5KM9; 5KMC; 5O8I; 5OSY; 5RHN; 5WAA; 6B42; 6CVO; 6CVP; 6CVQ; 6CVR; 6CVS; 6FIT; 6G9Z; 6IQ1; 6J53; 6J58; 6N3V; 6N3W; 6N3X; 6N3Y; 6RHN; 6YI0; 6YPR; 6YPX; 6YQD; 6YQM; 6YVP; 7Q2U; 8P8P; 8PA6; 8PA9; 8PAF; 8PAI; 8PWK
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